Clinical Trials on Primary Open-angle Glaucoma (POAG)

Total 971 results

Alcon Research

Completed

Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent (COMPASS XXT)

Primary Open Angle Glaucoma | Cataract

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Efficacy Mydrane ® for Cataract Surgery in Patients With Concomitant Primary Open Angle Glaucoma. (MIGA)

Cataract Surgery

Italy
Whitecap Biosciences, LLC

Completed

Safety and IOP-Lowering Effects of WB007

Ocular Hypertension | Glaucoma, Primary Open Angle

United States
Qlaris Bio, Inc.

Completed

Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Comparing Xalacom And Xalatan In Patients With Primary Open Angle Glaucoma (POAG) Or Ocular Hypertension (OH).

Ocular Hypertension | Glaucoma

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United Kingdom, France, Australia, Thailand, Portugal, Pakistan, Czechia, Greece
Laboratoires Thea

Completed

Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit Dose

Primary Open Angle Glaucoma | Ocular Hypertension

France
Laboratorios Sophia S.A de C.V.

Terminated

Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension (COMPLIANCE)

Primary Open Angle Glaucoma | Ocular Hypertension

Mexico
Nephron Pharmaceuticals Corporation

Completed

Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

Glaucoma

United States, Singapore
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-

Primary Open Angle Glaucoma | Ocular Hypertension

Japan
Chong Kun Dang Pharmaceutical

Unknown

Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Daily

Ocular Hypertension | Glaucoma, Primary Open Angle

Korea, Republic of
Alcon Research
University of California, San Diego

Completed

Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
ForSight Vision5, Inc.

Completed

A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

Latvia
Azienda Socio Sanitaria Territoriale degli Spedali...
Aristotle University Of Thessaloniki

Completed

Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) (SAF-24H-IOP)

Primary Open Angle Glaucoma | Ocular Hypertension

Greece, Italy
Northwestern Ophthalmic Institute S.C.
Research to Prevent Blindness

Completed

Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Wills Eye
Tanta Medical School, Tanta University

Withdrawn

IOP and Medication Reduction in MIGS Procedures

Primary Open Angle Glaucoma | Open Angle Glaucoma | Pigmentary Glaucoma | Pseudoexfoliation Glaucoma in Both Eyes

United States
St. Erik Eye Hospital

Recruiting

Monitoring of the IOP After SLT Using iCare Home

Pseudo Exfoliation Syndrome | Glaucoma Open-Angle Primary

Sweden
Ocular Therapeutix, Inc.

Completed

A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert

Open Angle Glaucoma and Ocular Hypertension

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

Effect of MEMOPTIC on Visual Field of Patients Followed for a Chronic Open-angle Glaucoma (MEMO-GCAO)

Open-angle Glaucoma | Visual Field

France
Ivantis, Inc.

Completed

Comparing Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery

Primary Open Angle Glaucoma | Pseudoexfoliative Glaucoma | Pigmentary Dispersion Glaucoma

United States
The University of Hong Kong
Icare Finland Oy

Not yet recruiting

Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression

Primary Open Angle Glaucoma | Glaucoma | Intraocular Pressure
Betaliq, Inc.
Trial Runners, LLC; Summit Analytical, LLC

Completed

Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Glaukos Corporation

Completed

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent Inject) or Travoprost

Open-angle Glaucoma

Armenia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patients

Ocular Hypertension | Glaucoma | Open-angle Glaucoma

Germany
Allergan

Completed

Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States, Israel, Canada, Singapore, Philippines, Spain, Australia, Belgium, Brazil, Germany
Aerie Pharmaceuticals

Completed

Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Santen Inc.

Completed

Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension (SEE-1)

Ocular Hypertension | Open-angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension (Rocket-1)

Ocular Hypertension | Open-angle Glaucoma

United States
Aerie Pharmaceuticals

Completed

Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Mati Therapeutics Inc.

Completed

A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon, a Novartis Company

Completed

Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution

Ocular Hypertension | Open-Angle Glaucoma

Japan
Alcon Research

Completed

A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma
Ono Pharmaceutical Co. Ltd

Completed

A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG)

Ocular Hypertension | Open Angle-glaucoma

United States
Ophthalmic Consultants Centres, Canada
Alcon Research

Completed

A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma (DVX)

Ocular Hypertension | Open-Angle Glaucoma

Canada
Vistakon Pharmaceuticals

Completed

A Comfort Survey of Open-angle Glaucoma or Ocular Hypertension Patients Treated With 2 Drugs

Ocular Hypertension | Open-angle Glaucoma

United States
Allergan

Terminated

A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

China
Alcon Research

Completed

Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
University Hospital, Bordeaux

Completed

Corneal Biomechanics and Continuous IOP Monitoring Using Soft Contact Lenses in Glaucomatous Patients (BIOLENS)

Open Angle Glaucoma With a Progressive Visual Field

France
Alcon Research

Terminated

Safety and Intraocular Pressure (IOP) Lowering Effect of AL-59412C

Ocular Hypertension | Open-angle Glaucoma
Mati Therapeutics Inc.
QLT Inc.

Completed

A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)

Ocular Hypertension | Open-Angle Glaucoma

United States
University of Zurich

Unknown

IOP Lowering Effect of PLT Versus SLT in Naiv OAG Patients

Ocular Hypertension | Open Angle Glaucoma,

Switzerland
Alcon Research

Terminated

Study of TRAVATAN in Subjects With Iris Pigmentation Changes

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

China
Santen Oy

Completed

Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies

Ocular Hypertension | Open-angle Glaucoma

Finland
Alcon Research

Completed

Adjunctive Study of AL-37807 Ophthalmic Suspension

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Terminated

Phase 4 Study Comparing IOP Lowering in OAG or OH in Caucasian or Japanese Subjects C-02-32

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

Adherence Assessment With Travalert Dosing Aid

Ocular Hypertension | Open-angle Glaucoma

Spain

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