Clinical Trials on Primary Open-angle Glaucoma and Ocular Hypertension

Total 4248 results

Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United Kingdom, France, Australia, Thailand, Portugal, Pakistan, Czechia, Greece
Laboratoires Thea

Completed

Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit Dose

Primary Open Angle Glaucoma | Ocular Hypertension

France
Laboratorios Sophia S.A de C.V.

Terminated

Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension (COMPLIANCE)

Primary Open Angle Glaucoma | Ocular Hypertension

Mexico
Nephron Pharmaceuticals Corporation

Completed

Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

Glaucoma

United States, Singapore
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-

Primary Open Angle Glaucoma | Ocular Hypertension

Japan
Chong Kun Dang Pharmaceutical

Unknown

Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Daily

Ocular Hypertension | Glaucoma, Primary Open Angle

Korea, Republic of
Alcon Research
University of California, San Diego

Completed

Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
ForSight Vision5, Inc.

Completed

A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

Latvia
Azienda Socio Sanitaria Territoriale degli Spedali...
Aristotle University Of Thessaloniki

Completed

Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) (SAF-24H-IOP)

Primary Open Angle Glaucoma | Ocular Hypertension

Greece, Italy
Northwestern Ophthalmic Institute S.C.
Research to Prevent Blindness

Completed

Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Sensimed AG

Terminated

Intraocular Pressure (IOP) Patterns in Fast Versus Slow Visual Field (VF) Progression Patients

Primary Open-angle Glaucoma (POAG) Patient

United States
Vanak Eye Surgery Center

Completed

Re-Trabeculectomy Versus Ahmed Glaucoma Valve Implantation in Secondary Surgical Management of Patients With Refractory Glaucoma

Refractory Primary Open Angle Glaucoma

Iran, Islamic Republic of
Wills Eye

Recruiting

Caffeine Consumption in Glaucoma Patients and Healthy Subjects

Glaucoma, Primary Open Angle

United States
Sensimed AG

Completed

Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sensor

Primary Open Angle Glaucoma | Healthy Subjects

United States
Moorfields Eye Hospital NHS Foundation Trust

Completed

Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension (LIGHT)

Primary Open Angle Glaucoma | Ocular Hypertension

United Kingdom
Medical University of Vienna

Completed

Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Physiology | Retina

Austria
University of California, San Diego
National Eye Institute (NEI)

Recruiting

Diagnostic Innovations in Glaucoma Study (DIGS)

Primary Open Angle Glaucoma | Myopia

United States
Transcend Medical, Inc.

Completed

Safety and Performance Study of the CyPass System Applier Model 241 (RePASS)

Open Angle Glaucoma (OAG)

Germany
AbbVie

Recruiting

Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle Glaucoma

Open-Angle Glaucoma

United States, Australia
Ivantis, Inc.

Completed

Hydrus Microstent for Refractory Open-Angle Glaucoma (SUMMIT)

Open-angle Glaucoma

Spain, United States, United Kingdom, Philippines, Colombia
Glaukos Corporation

Completed

Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty

Open-angle Glaucoma

Armenia
Annexon, Inc.

Completed

Single-dose Study of ANX007 in Participants With Primary Open-angle Glaucoma

Open-angle Glaucoma

United States
Alcon Research

Terminated

Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®

Ocular Hypertension | Open-angle Glaucoma

United States
Alcon Research

Completed

SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)

Ocular Hypertension | Open-Angle Glaucoma

United States
Lv Yingjuan

Completed

The Expression of Matrix Metalloproteinase 13, Tissue Inhibitor of Metalloproteinases 3, and Calcium-sensing Receptor in Human Trabecular Meshwork

Open-angle Glaucoma

China
Wills Eye

Completed

Dose, Effects and Characteristics of Pilocarpine

Open-angle Glaucoma

United States
Vistakon Pharmaceuticals

Completed

Safety and Efficacy of a Drug Delivery System in Glaucoma

Ocular Hypertension | Open-angle Glaucoma

United States
Alcon Research

Completed

Efficacy of Changing to TRAVATAN® From Prior Therapy

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma

Open-angle Glaucoma

United States
Alcon Research

Completed

DuoTrav® Eye Drops As Replacement Therapy Program

Ocular Hypertension | Open-angle Glaucoma

China
Aeon Astron Europe B.V.

Unknown

Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Trabeculectomy: A Study in Germany

Open-angle Glaucoma

Germany
Santen Oy

Completed

Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops

Ocular Hypertension | Open-Angle Glaucoma

Finland
Glaukos Corporation

Completed

A Study of the Glaukos Trabecular Micro-Bypass Stent in Refractory Open Angle Glaucoma Subjects

Open-Angle Glaucoma

Spain, Germany, Italy, Netherlands
University Hospital, Basel, Switzerland

Completed

Influence of Prostaglandins on Ocular Blood Flow in Glaucoma Patients

Open-Angle Glaucoma

Switzerland
AbbVie

Active, not recruiting

Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States, Argentina, Australia, Bulgaria, Czechia, Denmark, Germany, Hungary, Ireland, Italy, New Zealand, Poland, Russian Federation, South Africa, Sweden, United Kingdom
AbbVie

Completed

A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Allergan

Completed

Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

China
Bausch & Lomb Incorporated

Completed

Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertension (LUNAR)

Ocular Hypertension | Open-Angle Glaucoma

United States
Bausch & Lomb Incorporated

Completed

Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension (APOLLO)

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research
Novartis Institute for BioMedical Research

Completed

A Three Part Study of MGV354 in Ocular Hypertension or Glaucoma

Ocular Hypertension | Open-Angle Glaucoma
Aerie Pharmaceuticals

Completed

Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Glaukos Corporation

Completed

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost

Open-angle Glaucoma

Armenia
Merck Sharp & Dohme LLC

Completed

Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED)

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Allergan

Completed

A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
FinnMedi Oy
Tampere University; The Laboratory and Pharmacy Public Utility of the Pirkanmaa...

Completed

The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma

Ocular Hypertension | Open-Angle Glaucoma

Finland
Alcon Research

Completed

A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Alcon Research

Completed

A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Safety and Efficacy of Travoprost/Timolol BAC-free

Ocular Hypertension | Open-Angle Glaucoma

Japan

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