Clinical Trials on Primary Osteosarcoma of Bone

Total 11697 results

Istituto Ortopedico Galeazzi

Unknown

Inhibition of SENP1 for the Suppression of OS Growth and Metastasis

Primary Osteosarcoma of Bone

Italy
Klinikum Stuttgart
Klinikum Kassel GmbH (COSS-Biobank)

Not yet recruiting

Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas (COSS-Registry)

Osteosarcoma | High Grade Sarcoma | Recurrent Osteosarcoma | Bone Sarcoma | Undifferentiated Pleomorphic Sarcoma | Bone Tumor | Extraskeletal Osteosarcoma | Osseous Sarcoma | Parosteal Osteosarcoma | Osteoblastic Osteosarcoma | Chondroblastic Osteosarcoma | Fibroblastic Osteosarcoma | Conventional Osteosarcoma | Conventional... and other conditions
University Hospital, Strasbourg, France

Completed

Genetic Characterisation of High-grade Paediatric Osteosarcomas

Paediatric Osteosarcomas

France
Peking University People's Hospital

Recruiting

Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum

Osteosarcoma of Pelvis

China
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children

Osteosarcoma | Localised High Grade Osteosarcoma of the Limbs

France
Children's Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic Osteosarcoma | Localized Osteosarcoma | Unresectable Osteosarcoma | Resectable Osteosarcoma
M.D. Anderson Cancer Center

Suspended

Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study

Recurrent Osteosarcoma | Refractory Osteosarcoma | Metastatic Osteosarcoma | Unresectable Osteosarcoma | Locally Advanced Osteosarcoma

United States
Dana-Farber Cancer Institute
Harvard University; Conquer Cancer Foundation; Alex's Lemonade Stand Foundation; Sam Day Foundation

Recruiting

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

Ewing Sarcoma of Bone | Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor | Peripheral Primitive Neuroectodermal Tumor of Bone | High-grade Osteosarcoma | Ewing Sarcoma of Soft Tissue | Peripheral Primitive Neuroectodermal Tumor of Soft Tissue

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma | Osteoblastic Osteosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of Blood Samples From Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
Institut Cancerologie de l'Ouest

Completed

Long-term Evaluation of the Quality of Life of Former Patients Treated With Orthopedic Surgery, With or Without Radiotherapy (STARTos)

Osteosarcoma in Children

France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma | Stage IV Osteosarcoma AJCC v7 | Stage IVA Osteosarcoma AJCC v7 | Stage IVB Osteosarcoma AJCC v7 | Metastatic Osteosarcoma

United States, Canada, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
National Cancer Institute (NCI)

Suspended

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic Osteosarcoma | Localized Osteosarcoma | High Grade Osteosarcoma | Secondary Osteosarcoma

United States
Sarcoma Alliance for Research through Collaboration

Active, not recruiting

SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma

Osteosarcoma | Osteosarcoma Recurrent | Osteosarcoma Metastatic | Osteosarcoma in Children

United States
Istituto Ortopedico Rizzoli

Completed

an Istitution Experience on Parosteal OsTeosarcoma

Parosteal Osteosarcoma

Italy
Italian Sarcoma Group

Completed

Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma (SERIO)

Metastatic Osteosarcoma | Relapsed Osteosarcoma

Italy
UNICANCER

Recruiting

A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas (REGOBONE)

Chondrosarcomas | Ewing Sarcomas | Osteosarcomas | Chondroma | CIC-Rearranged Sarcoma

France
Children's Oncology Group
National Cancer Institute (NCI); University College, London; Medical Research...

Completed

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma (EURAMOS-1)

Metastatic Osteosarcoma | Localized Osteosarcoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Dana-Farber Cancer Institute

Active, not recruiting

Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone

Bone Cancer

United States
Italian Sarcoma Group
Scandinavian Sarcoma Group; Cooperative Osteosarcoma Study Group

Completed

European Study in Bone Sarcoma Patients Over 40 Years (EUROBOSS)

Osteosarcoma | Spindle Cell Sarcoma of Bone

Italy, Germany, Sweden
Children's Oncology Group
National Cancer Institute (NCI)

Completed

DNA Biomarkers in Tissue Samples From Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
Institute of Mother and Child, Warsaw, Poland
Maria Sklodowska-Curie National Research Institute of Oncology

Recruiting

Regorafenib in Patients With Refractory Primary Bone Tumors (Regbone)

Osteosarcoma | Ewing Sarcoma of Bone

Poland
Beijing Immunochina Medical Science & Technology...
Guangdong Provincial People's Hospital

Not yet recruiting

IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma

China
Azienda Ospedaliera Ospedale Infantile Regina Margherita...

Completed

Study of Effectiveness of GEMDOX in Relapsed Osteosarcoma

Osteosarcoma Recurrent | Osteosarcoma Metastatic

Italy
Italian Sarcoma Group

Recruiting

Observational Study on Skeletal Ewing's Sarcoma (EWOss)

Ewing Sarcoma of Bone

Italy
Ipsen

Not yet recruiting

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma (CabOSTar)

Osteosarcoma | Osteosarcoma in Children | Osteosarcoma in Adolescents and Young Adults
Blokhin's Russian Cancer Research Center

Recruiting

Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors

Sarcoma | Neoplasms, Connective and Soft Tissue | Osteosarcoma | Neoplasms, Connective Tissue | Sarcoma of Bone

Russian Federation
Eleison Pharmaceuticals LLC.

Completed

Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma

Pulmonary Relapse of Osteosarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma

Recurrent Ewing Sarcoma | Recurrent Osteosarcoma | Stage III Osteosarcoma AJCC v7 | Stage IV Osteosarcoma AJCC v7 | Stage IVA Osteosarcoma AJCC v7 | Stage IVB Osteosarcoma AJCC v7 | Metastatic Osteosarcoma | Metastatic Ewing Sarcoma | Unresectable Ewing Sarcoma | Unresectable Osteosarcoma

France
Italian Sarcoma Group

Terminated

Phase II Trial for the Treatment of Relapsed Osteosarcoma (OsteoREC2015)

OSTEOSARCOMA

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma | Refractory Osteosarcoma

United States
Dana-Farber Cancer Institute

Completed

Cabozantinib With Topotecan-Cyclophosphamide

Refractory Ewing Sarcoma | Refractory Osteosarcoma | Relapsed Ewing Sarcoma | Relapsed Osteosarcoma

United States
National Cancer Institute (NCI)

Completed

Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

Metastatic Osteosarcoma

United States
Italian Sarcoma Group
Associazione Italiana Ematologia Oncologia Pediatrica

Recruiting

Observational Study in Localized Osteosarcoma (ISG Os2Oss)

Localized Osteosarcoma

Italy
Memorial Sloan Kettering Cancer Center

Recruiting

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

Sarcoma | Soft Tissue Sarcoma | Bone Sarcoma

United States
University College, London
Richard Scowcroft Foundation

Terminated

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

Osteosarcoma | Spindle Cell Sarcoma of Bone

United Kingdom
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery

Bone Cancer | Chondrosarcoma | Recurrent Osteosarcoma | Clear Cell Sarcoma of the Kidney | Metastatic Osteosarcoma | Ovarian Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Uterine Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage III Uterine Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage...

United States
Lee's Pharmaceutical Limited

Not yet recruiting

Study of ZKAB001 for Maintenance Therapy in Patients With High-grade Osteosarcoma After Adjuvant Chemotherapy

High-grade Osteosarcoma
Université de Reims Champagne-Ardenne

Recruiting

Neutrophils in Bone Sarcomas (TANOs)

Osteosarcoma, Chondrosarcoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence (OSE)

Adults Treated During Childhood or Adolescence for a Malignant Bone Tumor (Osteosarcoma and Ewing Sarcoma)

France
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Jazz Pharmaceuticals

Terminated

Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma

Metastatic Osteosarcoma

United States
Sidnei Epelman

Unknown

Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma

Refractory or Relapsed Osteosarcoma

Brazil
Istituto Ortopedico Rizzoli

Recruiting

Tumor Microenvironment in Patients With Localized Osteosarcoma Treated With Mifamurtide: a Translational Study (Micros)

Localized Osteosarcoma

Italy
George Clinical Pty Ltd
Novartis

Terminated

Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

Osteosarcoma | Metastatic Osteosarcoma

United States
Children's Cancer Hospital Egypt 57357

Completed

Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements.

Osteosarcoma | Ewing Sarcoma of Bone

Egypt
Cairo University

Unknown

Non Grafted Maxillary Sinus Floor Elevation With Implant Placement Versus the Use of Short Endosseous Implants

Marginal Bone Loss | Primary Stability of Implants

Egypt
Peking University People's Hospital
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib With Ifosfamide Plus Etoposide for Relapsed or Refractory Osteosarcoma (OAIE) (OAIE)

Toxicity | Effect of Drug | Drug

China
Henan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study.

Osteosarcoma, Advanced

China
Istituto Ortopedico Rizzoli

Completed

Chemotherapy-induced Necrosis in Ewing Sarcoma

Ewing Sarcoma of Bone

Italy

Clinical Trials on Primary Osteosarcoma of Bone

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