Clinical Trials on Progression-free Survival;Progression-free Survival;Disease Control Rate; Safety

Total 522 results

The First Affiliated Hospital of Xiamen University

Not yet recruiting

Apatinib Combined With Capecitabine Second-line Treatment of Advanced Gastric Cancer: a Single-arm Exploratory Clinical Pilot Trial

Progression-free Survival;Progression-free Survival;Disease Control Rate; Safety

China
Grupo Hospital de Madrid

Completed

Study of Target-Guided Chemotherapy in Metastatic Colorectal Patients (TT)

Progression Free Survival

Spain
Peking University

Completed

IPO-NEC Trial:Study on the Efficacy and Safety Using Sequential IP Therapy and Oct Lar in the Treatment of Advanced GI NEC

Progression Free Survival of the Treatment

China
AstraZeneca

Completed

Study of Faslodex With or Without Concomitant Arimidex Versus Exemestane Following Progression on Non-steroidal Aromatase Inhibitors (NSAI)

Progression-free Survival

Korea, Republic of
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Safety and Efficacy of Oral Etoposide Combined With Antirotinib and Envollizumab in Elderly Patients With Lung Cancer

Progression Free Survival(PFS)
Peking Union Medical College Hospital
OrigiMed

Recruiting

Real-world Study for Patients With Advanced Hepatobiliary Tumors

Quality of Life | Objective Response Rate | Overall Survival | Progression-free Survival | Disease Control Rate | Duration of Response | Five-year Survival Rate

China
Qinghai Red Cross Hospital

Recruiting

Survival With Olanzapine in Patients With Locally Advanced or Metastatic Upper Gastrointestinal and Lung Cancer

Advanced Cancer | Progression Free Survival | Olanzapine

China
Laibin People's Hospital

Completed

A Retrospective Study of Radiotherapy Combined With EGFR-TKI for Stage III EGFR Mutant Lung Cancer

The Primary Study Metric is Progression-free Survival (PFS)
Zhejiang Cancer Hospital

Not yet recruiting

Advanced Pancreatic Cancer (PaC)

Progression-free Survival
Peking University People's Hospital
Xijing Hospital; Peking Union Medical College Hospital; Chinese PLA General Hospital and other collaborators

Withdrawn

Pegylated Liposomal Doxorubicin Versus Pirarubicin Plus Ifosfamide, Dacarbazine in Locally Advanced, Unresectable or Metastatic Soft-tissue Sarcoma (PDVPSTS)

Toxicity | Overall Survival | Progression-free Survival

China
Shanghai Jiao Tong University School of Medicine

Recruiting

Reduced MBF Regimen for Patients >=55 Years With Myeloid Malignancies

Disease-free Survival

China
Sun Yat-sen University
Shenzhen People's Hospital; Sixth Affiliated Hospital, Sun Yat-sen University; Dongguan People's Hospital and other collaborators

Not yet recruiting

Clinical Trial of Neoadjuvant Targeted Treatment to NSCLC Patients

2-year Disease-Free Survival

China
Peking University People's Hospital
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma (APFAO)

Toxicity | Overall Survival | Progression-free Survival | Clinical Benefit Rate

China
Sheng Liu

Unknown

Clinical Study on Triple Negative Breast Cancer With Chinese Medicine

Recurrence | Overall Survival | Progression-Free-Survival

China
First Affiliated Hospital of Zhejiang University
Zhejiang Cancer Hospital; Second Affiliated Hospital, School of Medicine, Zhejiang... and other collaborators

Recruiting

Prospective Multicenter Clinical Study of Neoadjuvant Imatinib Mesylate for Gastrointestinal Stromal Tumors (ZJGIST-01)

Gastrointestinal Stromal Tumor | Progression-free Survival | Neoadjuvant

China
Zhujiang Hospital

Recruiting

A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial

High Grade Glioma | Radiation Toxicity | Overall Survival | Progression-free Survival | MRI Simulated Positioning

China
Chinese PLA General Hospital

Completed

Microwave Ablation Versus Laparoscopic Hepatectomy for 3-5cm Hepatocellular Carcinoma

Cost | Overall Survival | Progression-free Survival
Qingdao Central Hospital

Completed

Osimertinib or Docetaxel-bevacizumab as Third-line Treatment in EGFR T790M Mutated Non-Small Cell Lung Cancer

Progression Free Survival

China
Guangdong Provincial People's Hospital

Recruiting

Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection

NSCLC, Stage I | Disease Free Survival | Pulmonary Function Assessment

China
Lei Li

Recruiting

Combination of Nimotuzumab and Radiotherapy for Recurrent Uterine Cervical Squamous Carcinoma

Recurrent Cervical Carcinoma | Radiotherapy | Objective Response Rate | Overall Survival | Progression-free Survival | Epidermal Growth Factor Receptor | Nimotuzumab

China
Assistance Publique Hopitaux De Marseille

Completed

A Clinical Trial Using Metronomic Oral Low-dose Cyclophosphamide Alternating With Low-dose Oral Methotrexate With Continuous Celecoxib and Weekly Vinblastine in Children and Adolescents With Relapsed or Progressing soliD Tumours. (SFCE METRO 01)

Survival Without Progression

France
Peking University People's Hospital
Peking University; Northwestern University; University of Chicago

Unknown

Epigenetic Biomarker for Osteosarcoma

Histologic Response (Tumor Necrosis Rate) | Objective Response Rate for Neoadjuvant Chemotherapy, ORR | Progression-free Survival, PFS | Overall Survival, OS

China
Peking University People's Hospital

Completed

Transcatheter Intra-arterial Limb Infusion of Cisplatin for Extremity Osteosarcoma

Overall Survival | Pathological Response | Event-free Survival | Local-recurrence Free Survival

China
Hospital Universitario Virgen de la Arrixaca

Completed

Jejunoileal vs Gastric GIST in the Era of Imatinib.

Recurrence | Overall Survival | Disease-free Survival

Spain
Shanghai CP Guojian Pharmaceutical Co., Ltd.

Completed

Study for HER2-Overexpressed MBC Patients Treated by Cipterbin® Plus vinorelbinE (HOPES)

Adverse Events | Progress-free Survival | Overall Response Rate
Karen-Lise Garm Spindler

Recruiting

IMPROVE Intervention Trial Implementing Non-invasive Circulating Tumor DNA Analysis to Optimize the Operative and Postoperative Treatment for Patients With Colorectal Cancer (IMPROVE-IT)

Colorectal Cancer | Adjuvant Chemotherapy | Circulating Tumor DNA | Progression Free Survival

Denmark
Second Affiliated Hospital, School of Medicine,...
Ningbo Medical Center Lihuili Hospital; Sir Run Run Shaw Hospital; Zhejiang Provincial... and other collaborators

Not yet recruiting

Efficacy of Postoperative Radiotherapy for Atypical Meningioma Without Venous Sinus Invasion After Gross-total Resection

Radiotherapy | Meningioma Atypical | Adverse Effect of Radiation Therapy | Progression-Free Survival
RenJi Hospital

Recruiting

Id and Rd Maintenance Regimens After Induction of Remission in Multiple Myeloma.

Overall Survival | Progression Free Survival | Maintenance

China
Zhongnan Hospital

Recruiting

Surufatinib Alone or Combined With Anti-PD-1 mAb in the Treatment of Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma; Targeted Therapy; Progression-free Survival

China
Qingdao Central Hospital

Completed

Maintenance Therapy for Small-cell Lung Cancer

Progression Free Survival

China
Qingdao University

Unknown

A Study of Standard Treatment +/- Apatinib in Extensive Stage Small Cell Lung Cancer

Progression Free Survival

China
Lei Li

Recruiting

PD-1 Antibody and Radiotherapy for Recurrent Cervical Cancer

Recurrent Cervical Carcinoma | Radiotherapy | Immune Checkpoint Inhibitors | Overall Survival | Anti-programmed Death-1 Antibody | Metastatic Cervical Carcinoma | Persistent Advanced Cervical Carcinoma | Objective Remission Rate | Progression-free Survival | Severe Adverse Events

China
Guang'anmen Hospital of China Academy of Chinese...

Recruiting

Clinical Study on the Effect of Brucea Javanica Oil Emulsion Injection on the Survival of Patients With Advanced Colorectal Cancer Who Failed to Receive Multi-line Treatment

Quality of Life | Colorectal Cancer | Chinese Herbal Medicine | Progression-free Survival

China
Universidad de Extremadura

Unknown

Surgical Treatment of Pancreatic Metastases From Renal Cell Carcinoma (PANMEKID)

Overall Survival | Surgical Procedure | Disease Free Survival

Spain
Assistance Publique - Hôpitaux de Paris

Completed

An Open-label Phase II Study With SUTENT in Patients Suffering From Hormone Refractory Prostate Cancer (PROSUT)

Prostatic Neoplasms | Neoplasms, Hormone-Dependent | Survival Rate | Disease-Free Survival | Tumor Markers, Biological

France
Università degli Studi dell'Insubria

Completed

Laparoscopy for Primary Cytoreductive Surgery in Advanced Ovarian Cancer

Residual Tumor | Overall Survival | Disease-free Survival

Italy
Zhiyong Yu

Unknown

The Maintenance Regimen and Revised Regimen for Advanced Breast Cancer Survivors After First-line Salvage Therapy

Breast Cancer | Chemotherapy Effect | Disease-free Survival
Beijing Chao Yang Hospital

Recruiting

Surgery Without Neoadjuvant Chemoradiotherapy Compared With Neoadjuvant Chemoradiotherapy for Rectal Cancer With Negative Circumferential Resection Margin Based on MRI Assessment, a Perspective Multicenter Randomized Controlled Trial (SCRM-01)

Local Recurrence of Malignant Tumor of Rectum | Circumferential Resection Margin | Intraoperative Perforation of Rectum | Disease-free Survival | Overal Survival

China
Lei Li

Recruiting

Chromosomal Instability in Ovarian Cancer

Epithelial Ovarian Cancer | High-grade Serous Ovarian Carcinoma | Survival Outcomes | Overall Survival | Progression-free Survival | Chromosomal Instability | Somatic Copy Number Distortion | Minimal Residual Lesions

China
Matteo's Friends

Recruiting

Dynamic Changes in Circulating Tumour Cells Protein Expression (Liquid-DRER2)

Recurrence Free Survival

Italy
Monash University
National Health and Medical Research Council, Australia; National Heart Foundation...

Active, not recruiting

A Clinical Trial of STAtin Therapy for Reducing Events in the Elderly (STAREE) (STAREE)

Healthy | Elderly | Independent Living | Disability Free Survival

Australia
Fuda Cancer Hospital, Guangzhou

Completed

Combination of PD-1 and VEGFR-2 Blockade for Advanced Hepatocellular Carcinoma

Progress Free Survival (PFS) and Overall Survival (OS)

China
Ferrer Internacional S.A.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy
University of Milan

Unknown

Prognostic Impact of Anatomical Resection Vs. Non-anatomical Resection for HCC (ARversusNAR)

Overall Survival | Patients Affected by Hepatocellular Carcinoma | Disease-Free Survival

Italy
Lei Li

Recruiting

HRD and Resistance to PAPPi in EOC Patients

Epithelial Ovarian Cancer | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation | Drug Resistance | Overall Survival | Progression-free Survival | Poly(ADP-ribose) Polymerase Inhibitor

China
Massimo Falconi

Active, not recruiting

Efficacy of Chemopreventive Agents on Disease-free and Overall Survival in Patients With Pancreatic Ductal Adenocarcinoma: The CAOS Study (CAOS)

Pancreatic Cancer | Overall Survival | Disease Free Survival

Italy
Lei Li

Unknown

A Genomic Analysis of Evolution of Epithelia Ovarian Tumors

Epithelial Ovarian Cancer | Progression-free Survival | Epithelial Ovarian Tumor of Borderline Malignancy | Driving Mutations

China
AB Science

Completed

Efficacy and Safety of Masitinib in the Treatment of Progressive Multiple Sclerosis

Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive | Multiple Sclerosis, Relapse Free

Poland, Spain, Bulgaria, France, Germany, Greece, Romania
Eye & ENT Hospital of Fudan University

Recruiting

A Prospective Exploratory Clinical Study of Metronomic Capecitabine as Adjuvant Therapy in Locoregionally Advanced Hypopharyngeal Carcinoma

to Explore Whether the Adjuvant Therapy of Metronomic Capecitabine Could Improve the Disease-free Survival of Locoregionally Advanced Hypopharyngeal Carcinoma

China
Peking University People's Hospital
Xijing Hospital; Beijing Friendship Hospital; Peking Union Medical College Hospital and other collaborators

Recruiting

Effect of Concurrent Capecitabine-based Long-term Radiotherapy Followed by XELOX Plus TME in Patients With High Risk Rectal Cancer: a Multi-centers, Randomized Controlled, Open-Label Trial (EXPLORE)

Rectal Cancer | Pathological Complete Response | Disease Free Survival

China

Clinical Trials on Progression-free Survival;Progression-free Survival;Disease Control Rate; Safety

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