Clinical Trials on Pulmonary Hypertension in United Kingdom

Total 6104 results

Sheffield Teaching Hospitals NHS Foundation Trust

Withdrawn

Investigating a Well-being Review in Pulmonary Hypertension

Pulmnary Hypertension

United Kingdom
Papworth Hospital NHS Foundation Trust
Merck Sharp & Dohme LLC

Completed

Serum Bio-markers in Pulmonary Hypertension

Pulmonary Hypertension, Primary, 4

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Chronic Thrombo-embolic Pulmonary Hypertension: Classification and Long Term Outcome

Idiopathic Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

United Kingdom
Papworth Hospital NHS Foundation Trust
Medical Research Council; University of Cambridge

Completed

StratosPHere (Non-interventional Study)

Pulmonary Arterial Hypertension | Pulmonary Hypertension | Idiopathic Pulmonary Arterial Hypertension | Respiratory Disease

United Kingdom
GlaxoSmithKline

Completed

Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) Patients

Hypertension, Pulmonary

United Kingdom
Imperial College London

Completed

The Study of Apelin-APJ System on Pulmonary Hypertension Patients and Healthy Subjects (EXAP)

Idiopathic Pulmonary Arterial Hypertension

United Kingdom
Papworth Hospital NHS Foundation Trust

Recruiting

RV Conductance Catheter Assessment During Balloon Pulmonary Angioplasty (RVBPA)

Chronic Thromboembolic Pulmonary Hypertension

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Liverpool John Moores University

Enrolling by invitation

Applying Artificial Intelligence to the 12 Lead ECG for the Diagnosis of Pulmonary Hypertension: an Observational Study

Pulmonary Hypertension (Diagnosis)

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Cambridge; University of Newcastle Upon-Tyne and other collaborators

Recruiting

Pulmonary Hypertension: Intensification and Personalisation of Combination Rx (PHoenix)

Pulmonary Arterial Hypertension

United Kingdom
Golden Jubilee National Hospital

Unknown

Inspiratory Muscle Training in Pulmonary Arterial Hypertension

Pulmonary Hypertension

United Kingdom
University of Alberta
Imperial College London

Completed

Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension

Pulmonary Hypertension (Idiopathic, Familial or Anorexigen-associated)

Canada, United Kingdom
National Health Service, United Kingdom

Completed

The Effect of Adding Exercise Training to Optimal Therapy in PAH

Pulmonary Arterial Hypertension

United Kingdom
Imperial College London
United Therapeutics

Completed

Qutenza®-Remodulin® in Pulmonary Arterial Hypertension Patients

Pain | Pulmonary Hypertension

United Kingdom
Papworth Hospital NHS Foundation Trust
Roche Pharma AG; National Institute for Health Research, United Kingdom

Completed

A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension (TRANSFORM-UK)

Pulmonary Arterial Hypertension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Actelion

Completed

Assessing the Repeatability of NT-proBNP Testing Using Laboratory and Point of Care Testing in PAH (REPEAT-PAH)

Pulmonary Artery Hypertension

United Kingdom
Bial - Portela C S.A.

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIA 5-1058

Pulmonary Arterial Hypertension | Cardiovascular Disease+Pulmonary Disease

United Kingdom
University of Aarhus
Medical University of Vienna; KU Leuven; Amsterdam UMC, location VUmc; St. Antonius... and other collaborators

Recruiting

BPA vs. PEA in CTEPH (GO-CTEPH)

Chronic Thromboembolic Pulmonary Hypertension

Denmark, United Kingdom
University of Cambridge
Medical Research Council; British Heart Foundation

Recruiting

National Cohort Study of Idiopathic and Heritable Pulmonary Arterial Hypertension (NAIAD)

Pulmonary Arterial Hypertension

United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Non-Interventional Follow Up Study For Subjects Who Received Sildenafil for Persistent Pulmonary Hypertension of the Newborn (PPHN)

Pulmonary Hypertension, Persistent, of the Newborn

United Kingdom
Golden Jubilee National Hospital
NHS Lothian; Imperial College Healthcare NHS Trust

Unknown

Effects of Apelin on the Lung Circulation in Pulmonary Hypertension

Heart Failure | Pulmonary Arterial Hypertension

United Kingdom
Oxford University Hospitals NHS Trust
Malmö University

Completed

Evaluation of the Usefulness of Adopting Remote, Mobile-based 6MWT Among Hospital Outpatients (the 6-APPnow), Within the Constraints Imposed by the SARS-COV2 Pandemic (6-APPnow)

Pulmonary Hypertension

United Kingdom
Golden Jubilee National Hospital

Unknown

Neural Respiratory Drive in Pulmonary Hypertension

Pulmonary Hypertension

United Kingdom
Royal Free Hospital NHS Foundation Trust
British Heart Foundation; Actelion

Unknown

Assessment of Cardiac Function Using Combined Cardiovascular Magnetic Resonance and Cardiopulmonary Exercise Testing (CMR-CPET) (CMR-CPET)

Pulmonary Hypertension

United Kingdom
Oxford University Hospitals NHS Trust
University of Oxford

Completed

Evaluation of a New 6 Minute Walk Test Smartphone App in Patients With Pulmonary Hypertension (6-APP)

Pulmonary Hypertension

United Kingdom
University of Dundee
NHS Tayside; NHS Fife; Chief Scientist Office of the Scottish Government

Completed

Do Phosphodiesterase 5A Inhibitors Improve Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Pulmonary Hypertension?

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Janssen Research & Development, LLC; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

ADOPT: Improving Diagnosis of Pulmonary Hypertension With AI and Echo (ADOPT)

Pulmonary Hypertension

United Kingdom
Golden Jubilee National Hospital

Recruiting

Remote Exercise Testing in Patients With Pulmonary Hypertension

Pulmonary Hypertension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Manchester Metropolitan University

Completed

Pulmonary Hypertension and Measurement of Exercise Capacity Remotely (PERSPIRE)

Pulmonary Hypertension

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Novel Quantitative Magnetic Resonance Imaging (MRI) Measures in the Assessment and Follow-up of Patients With Pulmonary Hypertension (PH)

Pulmonary Hypertension

United Kingdom
Imperial College London

Unknown

Wave Intensity Analysis in the Pulmonary Artery

Pulmonary Hypertension

United Kingdom
SoniVie Inc.

Active, not recruiting

TReatment Of Pulmonary HYpertension 1 Study (TROPHY)

Pulmonary Arterial Hypertension

United Kingdom, Israel, Belgium
Cambridge University Hospitals NHS Foundation Trust
Wellcome Trust; University of Cambridge

Completed

Haemodynamic Effects of Apelin Agonists and Antagonists in Man in COPD With Raised Pulmonary Artery Pressures

Pulmonary Hypertension | COPD

United Kingdom
Imperial College London
University of Sheffield; Medical Research Council; University of Cambridge; National...

Active, not recruiting

Positioning Imatinib for Pulmonary Arterial Hypertension (PIPAH)

Pulmonary Arterial Hypertension

United Kingdom
University of Sheffield

Unknown

Anxiety Self-management Intervention for Pulmonary Hypertension

Anxiety Disorders | Anxiety | Pulmonary Arterial Hypertension | Pulmonary Hypertension

United Kingdom
University of Edinburgh
Encysive Pharmaceuticals

Completed

Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)

Pulmonary Arterial Hypertension | Vasodilation | Vasoconstriction

United Kingdom
Imperial College London
Medical Research Council

Completed

Simvastatin as a Treatment for Pulmonary Hypertension

Pulmonary Hypertension

United Kingdom, Germany
Imperial College London

Recruiting

Quantifying 18kDa TSPO Expression in the Lung in Pulmonary Artery Hypertension (PAH)

Healthy | Pulmonary Arterial Hypertension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Feasibility of Novel Clinical Trial Infrastructure, Design and Technology for Early Phase Studies in Patients With Pulmonary Hypertension (FIT-PH) (FIT-PH)

Pulmonary Hypertension

United Kingdom
University of Leicester
University Hospitals, Leicester

Completed

Right Heart Dysfunction and Pulmonary Hypertension Evaluation in Airway Disease Using Cardiac Magnetic Resonance (RiPAIR)

Pulmonary Disease, Chronic Obstructive | Asthma

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Novel MRI Techniques in the Evaluation of Pulmonary Vascular Disease

Pulmonary Hypertension

United Kingdom
International CTEPH Association

Terminated

Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study)

Chronic Thromboembolic Pulmonary Hypertension | CTEPH

Germany, United States, United Kingdom, France
Bial - Portela C S.A.
Covance

Completed

Effect of BIA 5 1058 on Cardiac Repolarization

Heart Failure | Cardiovascular Disease | Pulmonary Arterial Hypertension

United Kingdom
University of Leicester
University Hospitals, Leicester; British Heart Foundation; Heart Link Children...

Completed

Markers of Inflammation and Lung Recovery in ECMO Patients for PPHN (Mi-ECMO)

Persistent Pulmonary Hypertension of the Newborn

United Kingdom
Imperial College London
Medical Research Council; Royal Brompton & Harefield NHS Foundation Trust

Terminated

Transforming Growth Factor Beta Signalling in the Development of Muscle Weakness in Pulmonary Arterial Hypertension

Muscle Weakness | Pulmonary Arterial Hypertension

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Actelion

Unknown

Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study (B-PHIT)

Idiopathic Pulmonary Fibrosis | Pulmonary Hypertension | Interstitial Lung Disease | Nonspecific Interstitial Pneumonia

United Kingdom
Imperial College London

Completed

The Right Ventricular Pulmonary Circulation Continuum in Mitral Valve Disease Study (RIPCOM1)

Mitral Regurgitation | Pulmonary Hypertension

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Boehringer Ingelheim

Not yet recruiting

FIBRotic Interstitial Lung Disease With Nocturnal hypOXaemia and EXercise Induced desaTuRAtion (FIBRINOX-EXTRA)

Pulmonary Hypertension | Interstitial Lung Disease | Fibrosis Lung

United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

Study To Investigate Safety And Efficacy Of Sildenafil In The Newborns With Persistent Pulmonary Hypertension (PPHN)

Persistent Pulmonary Hypertension of the Newborn | Hypoxic Respiratory Failure | PPHN

United Kingdom
Imperial College London
Fu Wai Hospital, Beijing, China

Completed

IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients

Pulmonary Arterial Hypertension | Iron Deficiency

United Kingdom, China, Germany
Bial - Portela C S.A.

Completed

Safety and Efficacy of BIA 5-1058 in PAH

Pulmonary Arterial Hypertension

Austria, Germany, Italy, Portugal, Spain, United Kingdom

Clinical Trials on Pulmonary Hypertension in United Kingdom

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CROs in United States

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