Clinical Trials on Pulmonary Hypoplasia in United Kingdom

Total 3474 results

GlaxoSmithKline
Hammersmith Medicines Research; Covance Harrogate

Completed

A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects

Hypertension, Pulmonary

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Suspended

Development of Novel Physiological CMR Methods in Health and Disease

Myocardial Infarction | Coronary Artery Disease | Heart Failure | Pulmonary Hypertension

United Kingdom
Sunovion Respiratory Development Inc.

Completed

Study to Investigate the Dose Response, Safety and Efficacy of Nebulized EP-101(SUN101) in Patients With Chronic Obstructive Pulmonary Disease (COPD): GOLDEN-1 Study

Chronic Obstructive Pulmonary Disease

United States, United Kingdom
PROCEPT BioRobotics

Completed

Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue (WATER) (WATER)

Benign Prostatic Hyperplasia (BPH)

United States, Australia, United Kingdom, New Zealand
Kingston University
University College London Hospitals; St. George's Hospital, London

Completed

Toward Self-management in ILD

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Chronic Hypersensitivity Pneumonitis | Connective Tissue Related ILD | Fibrotic Lung Disease

United Kingdom
Theravance Biopharma
GlaxoSmithKline

Completed

A Study to Investigate the Pharmacology of a Dual Pharmacophore in Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Portsmouth Hospitals NHS Trust
Pfizer

Completed

MISSION COPD - Modern Innovative SolutionS in Improving Outcomes iN COPD (MISSION-COPD)

Pulmonary Disease, Chronic Obstructive

United Kingdom
Theravance Biopharma
GlaxoSmithKline

Completed

An Investigation Of The Interaction Of GSK961081 With Inhaled Beta-Agonist And Anti-Muscarinic Drugs.

Pulmonary Disease, Chronic Obstructive

Thailand, New Zealand, United Kingdom
Theravance Biopharma
GlaxoSmithKline

Completed

Study of GSK961081 in Healthy Volunteer Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Safety, Tolerability and Pharmacokinetics (PK) Study of GSK2269557 in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

A Study to Assess the Safety and Pharmacokinetics of Inhaled Doses of GSK233705 and GW642444 in Healthy Subjects.

Pulmonary Disease, Chronic Obstructive

United Kingdom
Queen Mary University of London

Completed

Comparison of Pulmonary Vein Isolation Using SmartTouch® Catheter With or Without Real-time Contact Force Data

Atrial Fibrillation | Atrial Fibrillation Ablation | Pulmonary Vein Isolation

United Kingdom
GlaxoSmithKline

Completed

Safety, Blood Levels and Effects of GW642444

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

A Study To Investigate Safety, Blood Levels And Effects Of Giving GW642444, By Mouth, By Inhalation & By Injection

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

QTc Study GSK573719+GW642444

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Absorption & Elimination of Radiolabelled GSK2269557

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

GSK573719 IV Enabling Study

Pulmonary Disease, Chronic Obstructive

United Kingdom
Imperial College London
Medical Research Council; Mitsubishi Tanabe Pharma Corporation

Completed

Enhancement of in-Vitro GC Function in Patients With COPD

COPD

United Kingdom
Actelion

Completed

Study of ACT-293987 (NS-304) in Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United Kingdom, Austria, Belgium, France, Germany, Hungary, Italy, Poland
Novartis Pharmaceuticals

Terminated

Safety, Pharmacokinetics and Efficacy Study of QCC374 in PAH Patients

Pulmonary Arterial Hypertension

Germany, Korea, Republic of, United Kingdom, United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Milrinone in Congenital Diaphragmatic Hernia

Persistent Pulmonary Hypertension of the Newborn | Congenital Diaphragmatic Hernia | Hypoxemic Respiratory Failure | Pulmonary Hypoplasia

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstruction.

Respiratory Disorders

Sweden, United Kingdom
Baylor College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Erythropoetin Neuroprotection for Neonatal Cardiac Surgery

Congenital Heart Disease | Hypoplastic Left Heart Syndrome | Transposition of the Great Arteries | Aortic Arch Hypoplasia or Interruption

United States
GlaxoSmithKline

Completed

Observational AVODART (Dutasteride) Study In Benign Prostatic Hyperplasia Subjects - OASIS

Prostatic Hyperplasia

United Kingdom
Synspira, Inc.

Terminated

A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis

Lung Diseases | Cystic Fibrosis | Pulmonary Disease | Antibiotic Resistant Infection | Respiratory Tract Disease | Cystic Fibrosis Pulmonary Exacerbation | Lung Inflammation | Burkholderia Infections | Lung Infection | Multi-antibiotic Resistance | Pulmonary Inflammation | Lung Infection Pseudomonal | Cystic Fibrosis... and other conditions

United Kingdom
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Imatinib Mesylate in Patients With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Austria, Germany, United States, United Kingdom
Novartis Pharmaceuticals

Completed

BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia

Chronic Obstructive Pulmonary Disease (COPD) With Cachexia

United States, United Kingdom, Netherlands
Mologic Ltd
University Hospitals, Leicester

Terminated

COPD Exacerbation Alert System With urinE anaLysis Using the HEADSTART Device (COPE-WEL)

COPD Exacerbation

United Kingdom
Castleman Disease Collaborative Network

Withdrawn

Castleman Disease Collaborative Network Biobank ("Castlebank")

Hyperplasia | Castleman Disease | Castleman's Disease | Giant Lymph Node Hyperplasia | Angiofollicular Lymph Hyperplasia | Angiofollicular Lymph Node Hyperplasia | Angiofollicular Lymphoid Hyperplasia | GLNH | Giant Lymph Node

United States
Actelion

Completed

Bosentan in Children With Pulmonary Arterial Hypertension Extension Study (FUTURE 2)

Pulmonary Arterial Hypertension

United States, France, Netherlands, Italy, Germany, Switzerland, United Kingdom
Novartis Pharmaceuticals

Terminated

Extension to CQTI571A2102 to Evaluate Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

Germany, Belgium, United Kingdom, United States, Lithuania, Italy, Australia
Alung Technologies

Withdrawn

Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure

Chronic Obstructive Pulmonary Disease | Respiratory Insufficiency | Asthma | Emphysema | Acute Respiratory Distress Syndrome

United Kingdom
Novartis Pharmaceuticals

Terminated

Clinical Study to Assess the Mode of Action of QBW251 in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Germany, Switzerland, Austria, United Kingdom
Lung Therapeutics, Inc

Recruiting

A Study to Evaluate LTI-03 in Newly Diagnosed Idiopathic Pulmonary Fibrosis (IPF) Patients

Idiopathic Pulmonary Fibrosis

United States, United Kingdom, Germany
University of Oxford
Oxford University Hospitals NHS Trust

Completed

Oxygen Nanobubble Drink Impact on Exercise in Pulmonary Fibrosis

Pulmonary Fibrosis

United Kingdom
University of Leicester
Genentech, Inc.; Biomedical Research Centre- Respiratory (Glenfield Hospital...

Completed

Anti-ST2 (MSTT1041A) in COPD (COPD-ST2OP) (COPD-ST2OP)

COPD Exacerbation

United Kingdom
Actelion

Completed

Bosentan in Children With Pulmonary Arterial Hypertension (FUTURE-1)

Pulmonary Arterial Hypertension

United States, France, Netherlands, Italy, Germany, Switzerland, United Kingdom
GlaxoSmithKline

Completed

To Assess the Excretion Balance and Pharmacokinetics of a Single Oral Dose of [14C]SB-681323 in Healthy Adult Males

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Clinical Study to Assess the Effects of SRT2104 and Prednisolone on Biomarkers in Blood in Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Not yet recruiting

Percutaneous Treatment of Partial Anomalous Pulmonary Venous Drainage

Partial Anomalous Pulmonary Venous Connection

United Kingdom
University of Dundee
British Lung Foundation; Newcastle University; University of Leicester; University... and other collaborators

Active, not recruiting

BPF Genetics of ILD Study (BPF GILD)

Idiopathic Pulmonary Fibrosis | Lung Diseases, Interstitial | Idiopathic Interstitial Pneumonias | Alveolitis, Extrinsic Allergic | Lung; Disease, Interstitial, With Fibrosis | Bird Fancier's Lung

United Kingdom
University of Oxford
British Heart Foundation; National Institute for Health Research, United Kingdom

Completed

Iron Status and Hypoxic Pulmonary Vascular Responses

Pulmonary Arterial Hypertension | Iron Deficiency | Lung Hypoxia

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
London School of Hygiene and Tropical Medicine; University of Bristol; University...

Recruiting

Artificial Intelligence to Improve Detection and Risk Stratification of Acute Pulmonary Embolism (AID-PE) (AID-PE)

Pulmonary Embolism

United Kingdom
Apreo Health, Inc.

Recruiting

Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema (BREATHE-2)

Emphysema or COPD

United Kingdom, Austria, Netherlands
Imperial College London

Completed

Semaglutide Use in Acute Pulmonary Embolism

Pulmonary Embolism

United Kingdom
Sociedad Española de Neumología y Cirugía Torácica
European Commission; SAVANA

Unknown

Chart Review of Patients With COPD, Using Electronic Medical Records and Artificial Intelligence (BigCOPData)

Chronic Obstructive Pulmonary Disease

Spain, Austria, Switzerland, United Kingdom
AstraZeneca

Completed

Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD

Poland, United Kingdom, Germany, Sweden, Denmark
Air Liquide Santé International

Terminated

Efficacy of Helium/Oxygen Compared to Air/Oxygen in Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) (ECHO/ICU)

Chronic Obstructive Pulmonary Disease

Belgium, France, Switzerland, Italy, Tunisia, United Kingdom
Kingston University

Completed

The Role of Physical Activity and Diet Within Pulmonary Sarcoidosis

Interstitial Lung Disease | Sarcoidosis | Sarcoidosis, Pulmonary | ILD

United Kingdom
GlaxoSmithKline

Completed

Relative Bioavailability Study of Marketed and Lower Dose Ambrisentan in Healthy Adult Participants

Hypertension, Pulmonary

United Kingdom

Clinical Trials on Pulmonary Hypoplasia in United Kingdom

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