Clinical Trials on Pulmonary Tuberculosis (TB)

Total 9370 results

Innovative Medicines for Tuberculosis
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation

Tuberculosis | Tuberculosis, Pulmonary

Switzerland
Universidad Central de Venezuela
The ENose Company, Zutphen, Netherlands; Foundation for Research in Mycobacteria...

Unknown

Diagnostic Trial to Validate the Use of the E-Nose in Pulmonary TB

Tuberculosis, Pulmonary | e-Nose

Venezuela
FDA Office of Orphan Products Development
University of Illinois at Chicago

Completed

Pilot Randomized Study of Paromomycin (Aminosidine) vs Streptomycin for Uncomplicated Pulmonary Tuberculosis

Tuberculosis, Pulmonary
Seoul National University Hospital

Completed

Co-Infection of NTM in Patients With Smear Positive Pulmonary TB

Tuberculosis, Pulmonary

Korea, Republic of
Sarawak General Hospital
Hospital Melaka, Melaka; Hospital Queen Elizabeth, Kota Kinabalu, Sabah; Institute... and other collaborators

Recruiting

A Prospective Observational Study on the Role of Transthoracic Ultrasound in Differentiating Tuberculous From Malignant Pleural Effusion (TUS-TBE)

Pleural Effusion | Tuberculosis, Pleural | Malignant Pleural Effusion

Malaysia
University of Bari
Doctors with Africa - CUAMM

Not yet recruiting

Comparative Efficacy of CUS, CXR and CAD in TB Diagnosis in LMIC (CUSTB)

Tuberculosis, Pulmonary
Huashan Hospital

Recruiting

Optimizing(O) RIfapentine-based(RI) Regimen and shortENing(EN) the Treatment of Drug-sensitive Tuberculosis(T) (ORIENT)

Tuberculosis, Pulmonary

China
Seoul National University Hospital
Pusan National University Hospital; Chonnam National University Hospital; Seoul... and other collaborators

Not yet recruiting

Treatment Shortening of Drug-Sensitive Pulmonary Tuberculosis Using High Dose Rifampicin (Hi-DoRi-3) (Hi-DoRi-3)

Tuberculosis, Pulmonary

Korea, Republic of
University College, London
National University Hospital, Singapore; Singapore Clinical Research Institute...

Completed

Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive Tuberculosis (TRUNCATE-TB)

Tuberculosis, Pulmonary

Singapore, Uganda, Thailand, Indonesia, Philippines, India
Federal University of Mato Grosso
Oswaldo Cruz Foundation

Terminated

Prevention of Tuberculosis in Prisons

Tuberculosis, Pulmonary | Antibiotic Prophylaxis

Brazil
Seoul National University Hospital
Samsung Medical Center; Pusan National University Hospital; Asan Medical Center; Chonnam National University Hospital and other collaborators

Not yet recruiting

A Prospective Registry For Patients With Non-Tuberculous Mycobacterial (NTM) Pulmonary Disease in Korea. (NTM-KOREA)

Pulmonary Disease | Pulmonary Infection | Non-Tuberculous Mycobacterial Pneumonia
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; McGill University; University... and other collaborators

Unknown

A Pragmatic Randomised Study to Optimise Screening, Prevention and Care for Tuberculosis in Malawi (PROSPECT)

Tuberculosis | Hiv | Tuberculosis, Pulmonary

Malawi
Shanghai Public Health Clinical Center
Zhejiang University; Yunnan Provincial Infectious Disease Hospital; Shenzhen... and other collaborators

Unknown

Rifampicin vs Rifabutin in HIV/AIDS Patients Combined With Tuberculosis (RRHT)

Tuberculosis, Pulmonary | AIDS

China
National Heart and Lung Institute
Kibong'oto Infectious Disease Hospital, Tanzania

Recruiting

Silicosis and Silicotuberculosis Among Small Scale Gemstone Miners in Northern Tanzania (SilicoTB)

Tuberculosis | Silicosis | Silicosis; With Tuberculosis

Tanzania
All India Institute of Medical Sciences, New Delhi
National AIDS Control Organisation

Completed

Efficacy and Safety of Concomitant Use of Nevirapine and Rifampicin With HIV-TB ("NVP")

HIV/TB Co-infection

India
ANRS, Emerging Infectious Diseases

Unknown

Interaction Between High Dose Rifampicine and Efavirenz in Pulmonary Tuberculosis and HIV Co-infection (RIFAVIRENZ)

HIV | Tuberculosis

Uganda
National Institute of Allergy and Infectious Diseases...

Completed

Diagnosing Tuberculosis in HIV Infected Children in Peru

HIV Infections | Tuberculosis | Tuberculosis, Pulmonary

Peru
Fakultas Kedokteran Universitas Indonesia

Enrolling by invitation

The Effectivity of Anti Tuberculosis Therapy in Idiopathic Uveitis With Positive IGRA

Tuberculous Uveitis

Indonesia
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
University of Cape Town
University of Stellenbosch; University of Cape Town Lung Institute; University... and other collaborators

Completed

An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosis (NEXT)

Tuberculosis | Multidrug Resistant Tuberculosis | Extensively-drug Resistant Tuberculosis

South Africa
University of Cape Town
University of Zurich; University of Bern; University of Stellenbosch; University...

Recruiting

Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion (StatinTB)

Tuberculosis, Pulmonary

South Africa
University of Siena

Unknown

IGRA and Mantoux Response in Children With Suspected Latent or Active TB Infection (TBTubercolar)

Tuberculosis, Pulmonary | Interferon-gamma Release Tests | Tuberculin Test

Italy
Pfizer

Completed

Safety And Efficacy Of Rifabutin In Patients For Non-HIV Patients

Tuberculosis | Non-tuberculous Mycobacterial Diseases (Including MAC Disease)
Assistance Publique - Hôpitaux de Paris

Completed

Positron Emission Tomography in Extrapulmonary Tuberculosis (TUBOGTEP)

Extrapulmonary Tuberculosis | Lymph Node Tuberculosis | Bone Tuberculosis

France
Centers for Disease Control and Prevention
Boston University; Pfizer; Columbia University; University of Texas; University of... and other collaborators

Completed

Linezolid Pharmacokinetics (PK) in Multi-Drug Resistant (MDR)/Extensively-Drug Resistant (XDR) Tuberculosis (TB) (S30PK)

Multi-Drug Resistant Tuberculosis | Extensively Drug Resistant Tuberculosis

South Africa
University Medical Center Groningen

Completed

Drug Interaction Study Between Linezolid and Clarithromycin in Tuberculosis Patients

Multidrug-resistant Tuberculosis | Extensively Drug-resistant Tuberculosis

Netherlands
Universidade Federal do Rio de Janeiro

Recruiting

Cardiopulmonary Function and Quality of Life in Pulmonary Tuberculosis

Quality of Life | Tuberculosis, Pulmonary | Physical Disability

Brazil
University of Alberta

Completed

Integrating Electronic Patient Reported Biometric Measures (ePReBMs) From Wearable Devices in Respiratory Diseases

Bronchiectasis | Cystic Fibrosis | Pulmonary Tuberculosis | Lung Transplant | Progressive Fibrosing Interstitial Lung Disease

Canada
National Cancer Center, Korea

Completed

Pharmacokinetics of Anti-tuberculosis Drugs in Gastrectomized Patients

Early Gastric Cancer | Tuberculosis | Tuberculosis, Pulmonary

Korea, Republic of
Ahmad Jabir Rahyussalim

Unknown

Effectivity of Mesenchymal Stem Cell on Vertebral Bone Defect Due to Mycobaterium Tuberculosis Infection

Mesenchymal Stem Cell | Spinal Tuberculosis

Indonesia
Centers for Disease Control and Prevention
Kenya Medical Research Institute

Completed

Brief Bactericidal Activity of Anti-Tuberculosis Drugs (BBA)

Tuberculosis | Drug-resistant Tuberculosis | Isoniazid Resistant Tuberculosis (Disorder)

India
Weill Medical College of Cornell University
Hamad Medical Corporation; Weill Cornell Medical College in Qatar

Withdrawn

Biologic Basis Of Increased Susceptibility Of Smokers To Pulmonary Infection With Mycobacterium Tuberculosis

Chronic Obstructive Pulmonary Disease | Tuberculosis

Qatar
Michael Hoelscher
German Federal Ministry of Education and Research; German Center for Infection... and other collaborators

Completed

A Single Ascending Dose Study of BTZ043

Lung Diseases | Bacterial Infections | Mycobacterium Infections | Tuberculosis | Tuberculosis, Pulmonary

Germany
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy and Safety of Modified Anti-tubercular Regimens in Treatment of Tuberculosis in Patients With Underlying Compensated and Decompensated Chronic Liver Disease

Chronic Liver Disease With Tuberclosis

India
Oxford University Clinical Research Unit, Vietnam
National Tuberculosis Program, Vietnam

Completed

Intensifying Multi-Drug Resistant Tuberculosis Contact Tracing by Social Network Analysis (SNAP)

Tuberculosis Infection

Vietnam
Shenzhen Third People's Hospital

Completed

Comparative Study of Nonintubated Uniport Thoracoscopic Surgery Using Thoracic Paravertebral Nerve Block Versus Intercostal Nerve Block for Peripheral Solitary Pulmonary Nodule Patients

Peripheral Solitary Pulmonary Nodule or Tuberculoma

China
Chinese University of Hong Kong
Prince of Wales Hospital, Shatin, Hong Kong

Completed

Multiplex PCR -Microarray-based Assay in the Detection of Mycobacterium

Tuberculosis | Non-Tuberculous Mycobacterial Pneumonia

Hong Kong
Stellah Mpagama
Radboud University Medical Center; University of St Andrews

Recruiting

A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosis (OptiRiMoxTB)

Tuberculosis | Human Immunodeficiency Virus

Tanzania
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients (PHOENIx MDR-TB)

Tuberculosis, MDR

Haiti, Tanzania, Thailand, Botswana, Brazil, India, Kenya, Peru, Philippines, South Africa, Uganda, Zimbabwe, Vietnam
Centers for Disease Control and Prevention
Yale University; Columbia University; University of KwaZulu

Completed

TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB (LiMiT)

Multi-drug Resistant Tuberculosis | Extensively Drug Resistant Tuberculosis

South Africa
Brigham and Women's Hospital
University of California, Los Angeles; University of Stellenbosch; University... and other collaborators

Recruiting

Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB (PRESCIENT)

HIV | Tuberculosis, Pulmonary

South Africa, Haiti
National Taiwan University Hospital

Unknown

Toward a Safe and Reachable Preventive Therapy for LTBI: a Multicenter Randomized Controlled Study in Taiwan

Latent Tuberculosis Infection

Taiwan
University of Aarhus
Bandim Health Project; Arla Foods

Terminated

Treating Tuberculosis Wasting With a High-protein Supplement (NUTRIATO)

Malnutrition | Tuberculosis | Tuberculosis, Pulmonary | Undernutrition

Guinea-Bissau
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Recruiting

Clinical Trial of Mica

Latent Tuberculosis Infection

China
University of Cape Town
Institute of Tropical Medicine, Belgium; Epicentre; Medecins Sans Frontieres,... and other collaborators

Recruiting

Pharmacometrics to Advance Novel Regimens for Drug-resistant Tuberculosis-PandrTB Tuberculosis (PandrTB)

Multi-drug Resistant Tuberculosis

Vietnam, Kazakhstan, Lesotho, Pakistan, Peru, South Africa
Boston Medical Center
Jawaharlal Institute of Postgraduate Medical Education & Research

Enrolling by invitation

Tuberculosis - Learning the Effect of Parasites and Reinforcing Diets (TB-LEOPARD)

Malnutrition | Tuberculosis, Pulmonary | Helminthiasis

United States, India
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Rewards for Tuberculosis Contact Screening (RECON)

Tuberculosis | Drug-resistant Tuberculosis

South Africa
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety and Efficacy Trial of Delamanid for 6 Months in Participants With Multidrug-resistant Tuberculosis

Multidrug-resistant Tuberculosis

South Africa, Estonia, Philippines, Peru, Lithuania, Latvia, Moldova, Republic of
Epicentre
Medecins Sans Frontieres, Netherlands

Completed

Evaluation of PCR Using DNA Extract From Slides and Filter Paper for the Detection of Tuberculosis and MDR-tuberculosis

Tuberculosis | Multi Drug Resistant Tuberculosis

Uganda
Janssen Research & Development, LLC

Recruiting

Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents Pulmonary MDR-TB

Multidrug-Resistant Tuberculosis

Mozambique, Philippines, Russian Federation, South Africa, Uganda, Ukraine

Clinical Trials on Pulmonary Tuberculosis (TB)

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