Clinical Trials on Rectum Neoplasm

Total 108473 results

Fabio Barra

Completed

Rectal Water-contrast Transvaginal Ultrasonography Versus Sonovaginography for the Diagnosis of Posterior Deep Pelvic Endometriosis

Endometriosis | Endometriosis, Rectum | Endometriosis of Vagina | Endometriosis Rectovaginal Septum | Endometriosis Pelvic | Endometriosis of Colon

Italy
Cancer Institute and Hospital, Chinese Academy...

Unknown

Short Course Radiotherapy Combined With Chemotherapy in Stage IV Rectal Cancer With Resectable Liver Metastases

Stage IV Rectal Cancer, Liver Metastasis, Resectable

China
Fox Chase Cancer Center

Completed

Adherence to Survivorship Care Guidelines in Health Care Providers for Non-Small Cell Lung Cancer and Colorectal Cancer Survivor Care

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small... and other conditions

United States
Claus Lindbjerg Andersen
University of Aarhus

Recruiting

ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial (IMPROVE-IT2)

Gastrointestinal Neoplasms | Colonic Diseases | Colorectal Neoplasms | Rectal Diseases | Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colonic Neoplasms | Gastrointestinal Cancer | Colo-rectal Cancer | Colonic Cancer | Digestive System Neoplasm | Digestive System Disease | Gastro-Intestinal Disorder | ctDNA

Denmark
University College, London

Not yet recruiting

Radioisotope and Fluorescence Guidance in Rectal Cancer

Rectal Cancer | Lymph Node Metastasis

United Kingdom
Asan Medical Center

Unknown

Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases

Rectal Cancer | Liver Metastases

Korea, Republic of
Imperial College London

Recruiting

Anal Cancer Risk In Women

Anal Cancer | Human Papilloma Virus | Anal Intraepithelial Neoplasia | Genital Neoplasm | Genital Cancer

United Kingdom
Institut Curie

Completed

Fibroblast Before and After Neoadjuvant Chemo-radiotherapy in Patient With Locally Advanced Rectal Adenocarcinoma (FibroRect)

Rectum Adenocarcinoma

France
Julie L. Sutcliffe, Ph.D
National Cancer Institute (NCI)

Active, not recruiting

First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide

Breast Carcinoma | Lung Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Metastatic Malignant Neoplasm in the Lung | Metastatic Malignant Neoplasm in the Breast | Metastatic Malignant Neoplasm in the Colon | Metastatic Malignant Neoplasm in the Rectum

United States
CENTOGENE GmbH Rostock

Completed

Peptide-based Immunization for Colon- and and Pancreas-carcinoma (PICOP-GLOBAL)

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Rectal Cancer | Rectal Neoplasms | Colon Cancer | Pancreas Cancer | Colo-rectal Cancer | Rectal Adenocarcinoma | Colon Neoplasm | Rectal Tumors | Colon Adenocarcinoma

Pakistan
West China Hospital

Unknown

Prediction Model for Lateral Lymph Node Metastasis

Rectal Cancer

China
Fudan University

Unknown

Detection and Enumeration of Circulating Tumor Cells in Rectal Cancer

Rectal Cancer

China
Region Västerbotten

Recruiting

FDG - PET / MRI in Patients With Rectal Cancer (RECTOPET)

Rectal Cancer | Lymph Node Metastases

Sweden
Korea Cancer Center Hospital
Gachon University Gil Medical Center; The Catholic University of Korea; Gangnam... and other collaborators

Unknown

Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis

Rectal Cancer | Liver Metastasis | Lung Metastasis

Korea, Republic of
City of Hope Medical Center

Completed

Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
National Cancer Institute (NCI)

Terminated

Neoadjuvant and Adjuvant Capecitabine and Oxaliplatin in Treating Patients With Resectable Liver Metastases Secondary to Colorectal Cancer

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Sahlgrenska University Hospital, Sweden
The Swedish Research Council; Sjöbergstiftelsen; VGregion

Recruiting

Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial (FIDURA)

Gynecologic Cancer | Malignant Neoplasm | Malignant Neoplasm of Large Intestine | Malignant Neoplasm of Colon | Malignant Neoplasm of Prostate | Malignant Neoplasm of Rectum | Malignant Neoplasm of Anus | Malignant Neoplasm of Urinary Bladder | Malignant Neoplasm of Cervix | Malignant Neoplasm of Ovary

Sweden
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Liver Metastases | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Beijing Chao Yang Hospital
Wuhan University; Shandong Provincial Hospital; Shandong Cancer Hospital and... and other collaborators

Unknown

Safety and Efficacy Study of Cylindrical Abdominoperineal Resection to Treat Rectal Cancer

Postoperative Complications | Rectal Cancer | Treatment | Neoplasm Recurrence, Local | Survival Rate

China
Region Västmanland

Completed

Lymph Node Metastases and Arterial Ligation in Rectal Cancer Surgery

Lymph Node Metastases
Memorial Sloan Kettering Cancer Center

Recruiting

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

Colorectal Cancer | Colon Cancer | Liver Metastasis Colon Cancer | Adenocarcinoma of the Rectum | Colon Cancer Liver Metastasis | Adenocarcinoma of the Colon

United States
Case Comprehensive Cancer Center

Recruiting

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon | Stage III Colorectal Cancer | Stage I Colorectal Cancer | Stage II Colorectal Cancer

United States
Ohio State University Comprehensive Cancer Center
Novartis Pharmaceuticals; National Comprehensive Cancer Network

Completed

Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
Sunnybrook Health Sciences Centre
University of Toronto; Sunnybrook Research Institute

Completed

Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer

Rectal Neoplasm Carcinoma in Situ Adenocarcinoma

Canada
National Institutes of Health Clinical Center (CC)

Completed

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

Liver Metastases | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Société Française d'Endoscopie Digestive
Cook Group Incorporated

Completed

Prospective Study Evaluating the Feasibility of Fiducial Markers Placement for Patients With Esophageal or Rectal Cancer (FIDECHO)

Rectal Neoplasms | Esophageal Neoplasm

France
National Cancer Center, China

Recruiting

Lateral Pelvic Lymph Node Dissection for Rectal Neuroendocrine Neoplasms Undergoing Laparoscopic Total Mesenteric Excision

Rectal Neuroendocrine Neoplasm

China
Amal Therapeutics
Boehringer Ingelheim

Active, not recruiting

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

Metastatic Colorectal Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer | MSS

United States, Belgium, Switzerland, Germany
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Rectal Adenocarcinoma

United States
SafeHeal Inc

Terminated

SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study (SAFE-2)

Colorectal Cancer | Rectal Cancer | Rectal Tumor | Rectal/Anal

United States, France, Belgium
National Cancer Institute (NCI)

Terminated

Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage II Rectal Cancer AJCC v8 | Locally Advanced Rectal Carcinoma

United States
City of Hope Medical Center

Withdrawn

Laparoscopic Surgery or Robotic-Assisted Laparoscopic Surgery in Treating Patients With Rectal Cancer That Can Be Removed By Surgery

Recurrent Rectal Cancer | Stage I Rectal Cancer | Stage II Rectal Cancer | Stage III Rectal Cancer
GlaxoSmithKline

Recruiting

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer (AZUR-1)

Neoplasms, Rectal

United States, France, Italy, Japan, Spain, United Kingdom, Germany, Korea, Republic of, Canada, Netherlands
National Cancer Institute (NCI)
NRG Oncology

Completed

Veliparib, Pembrolizumab, and Combination Chemotherapy in Treating Patient With Locally Advanced Rectal Cancer

Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v7 | Stage II Rectal Cancer AJCC v7

United States, Puerto Rico
Peking University Third Hospital

Recruiting

Application of MRI in Identifying Myelosuppression Risk of Neoadjuvant Chemoradiotherapy for Rectal Cancer

Rectal Cancer Stage II | Rectal Cancer Stage III

China
Prof. Dr. med. Claus Rödel
Johann Wolfgang Goethe University Hospital; Deutsche Krebshilfe e.V., Bonn...

Completed

Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer (CAOAROAIO-12)

Rectal Neoplasms | Rectal Cancer Stage II | Rectal Cancer Stage III

Germany
National Cancer Center, China

Not yet recruiting

Sentinel Lymph Node Biopsy in Rectal Cancer

Rectal Cancer Stage III | Rectal Cancer Stage IV

China
University Hospital Tuebingen

Recruiting

Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy. (CAO/ARO/AIO-16)

Rectal Cancer | Rectal Neoplasms | Rectal Cancer Stage II | Rectal Cancer Stage III

Germany
Fudan University
Shanghai Zhongshan Hospital; RenJi Hospital; First Hospital of China Medical... and other collaborators

Not yet recruiting

Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study

Rectal Cancer | RECTAL NEOPLASMS
National Cancer Institute (NCI)

Completed

Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer

Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v7 | Stage II Rectal Cancer AJCC v7

United States
J. Uriach and Company

Unknown

Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate.

Colorectal Neoplasm | Iron Deficiency Anemia

Spain
First Affiliated Hospital of Guangxi Medical University

Recruiting

The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer

Rectal Cancer | Rectal Cancer Stage II | Rectal Cancer Stage III

China
Jules Bordet Institute

Active, not recruiting

Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer (REGINA)

Rectal Cancer Stage II | Rectal Cancer Stage III

Belgium, France
OHSU Knight Cancer Institute
Oregon Health and Science University; Taiho Pharmaceutical Co., Ltd.

Recruiting

TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage IIA Rectal Cancer AJCC v8 | Stage IIB Rectal Cancer AJCC v8

United States
Sun Yat-sen University

Active, not recruiting

TNT to Increase the Clinical Complete Response Rate for Distal LARC (TESS)

Chemoradiation | Rectal Cancer | Rectal Cancer Stage II | Rectal Cancer Stage III

China
AUSL Romagna Rimini
AstraZeneca; Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori

Recruiting

Capecitabine Plus Concomitant Radiation Therapy Followed by Durvalumab as Preoperative Treatment in Rectal Cancer (PANDORA)

RECTAL CANCER

Italy
Radboud University Medical Center

Completed

Transanal Endoscopic Microsurgery (TEM) After Radiochemotherapy for Rectal Cancer (CARTS)

Rectal Tumour

Netherlands
Hospital Universitario Virgen de la Arrixaca

Completed

Prospective Randomised Study Comparing Laparoscopic Versus Open Surgery in Patients With Rectal Cancer

RECTAL CANCER
Institute of Oncology Ljubljana

Unknown

IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment (BISER)

Rectal Carcinoma

Slovenia
National University Hospital, Singapore
Tan Tock Seng Hospital

Unknown

Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer

Rectal Cancers.

Singapore

Clinical Trials on Rectum Neoplasm

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