Clinical Trials on Refractory Clear Cell Sarcoma of Soft Tissue

Total 3640 results

Dana-Farber Cancer Institute
Boston Children's Hospital

Completed

Vaccine Trial for Clear Cell Sarcoma, Pediatric Renal Cell Carcinoma, Alveolar Soft Part Sarcoma and Children With Stage IV Melanoma

Melanoma | Renal Cell Carcinoma | Sarcoma, Clear Cell | Sarcoma, Alveolar Soft Part

United States
Italian Sarcoma Group
PharmaMar

Recruiting

Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma (ISG-ARTICLE)

Soft Tissue Sarcoma | Leiomyosarcoma of Ovary

Italy
University of Washington
National Cancer Institute (NCI)

Completed

Pazopanib Hydrochloride Followed by Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma

Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage IIA Adult Soft Tissue Sarcoma

United States
Centre Leon Berard

Recruiting

Gene Signatures Searching of Sensitivity/Resistance to Neoadjuvant Radiotherapy in Patients With Resectable STS (RADIOSARC)

Soft Tissue Sarcomas

France
Brown University
Actuate Therapeutics Inc.

Withdrawn

Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma

Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma of Bone | Leiomyosarcoma | High Grade Sarcoma | Liposarcoma | Rhabdomyosarcoma | Angiosarcoma | Bone Sarcoma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Myxofibrosarcoma | Spindle Cell Sarcoma

United States
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Histiocytic and Dendritic Cell Neoplasm | Recurrent Langerhans Cell Histiocytosis | Recurrent Lymphoma | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant... and other conditions

United States, Puerto Rico, Australia
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Withdrawn

Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Primary or Recurrent Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IVA Adult Soft Tissue Sarcoma | Stage IIB Adult Soft Tissue Sarcoma | Stage IIC Adult Soft Tissue Sarcoma

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Recurrent Childhood Ependymoma | Advanced Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditions

United States, Puerto Rico
Assaf-Harofeh Medical Center

Unknown

A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma

Soft-Tissue Sarcoma | Liposarcomas, Dedifferentiated | Liposarcoma - Well Differentiated | Liposarcoma; Mixed Type

Israel
Memorial Sloan Kettering Cancer Center
Incyte Corporation

Active, not recruiting

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

Sarcoma | Soft Tissue Sarcoma | Soft Tissue Sarcoma Adult | Sarcoma,Soft Tissue

United States
University of Southern California
National Cancer Institute (NCI)

Completed

Real-Time Contrast-Enhanced Ultrasonography and Shear Wave Elastography in Predicting Treatment Response in Patients With Soft Tissue Sarcoma

Bone Sarcoma | Retroperitoneal Sarcoma | Adult Soft Tissue Sarcoma

United States
National Cancer Institute (NCI)

Recruiting

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Metastatic Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Unresectable Sarcoma

United States
National Cancer Institute (NCI)

Terminated

BMS-247550 in Treating Patients With Advanced Soft Tissue Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Malignant Solid Neoplasm | Recurrent Melanoma | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditions

United States, Puerto Rico
Di Wu

Not yet recruiting

Study of Anlotinib Hydrochloride and Toripalimab in Subjects With Unresectable or Metastatic Undifferentiated Pleomorphic Sarcoma

Undifferentiated Pleomorphic Sarcoma | Soft Tissue Sarcomas

China
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

GISAR German Interdisciplinary Sarcoma Registry (GISAR)

Sarcoma | Carcinosarcoma | Sarcoma,Soft Tissue | Sarcoma of Bone

Germany
Centre Leon Berard

Recruiting

Multiparametric Quantitative MRI and Response to Neoadjuvant Radiotherapy for Soft-tissue Sarcoma (SarQuantIRM)

Soft Tissue Sarcoma | Resectable Soft Tissue Sarcoma | Adult Soft Tissue Sarcoma

France
Wuhan Union Hospital, China

Recruiting

Camrelizumab Plus Doxorubicin for the First Line Treatment of Adcanced Soft Tissue Sarcoma

Soft Tissue Sarcoma | Neoplasms, Connective and Soft Tissue | Sarcoma Metastatic | Sarcoma,Soft Tissue

China
National Cancer Institute (NCI)
National Comprehensive Cancer Network

Completed

Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
National Cancer Institute (NCI)

Completed

Perifosine in Treating Patients With Advanced Soft Tissue Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Terminated

Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body Wall

Recurrent Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma AJCC v7 | Stage II Adult Soft Tissue Sarcoma AJCC v7 | Stage III Adult Soft Tissue Sarcoma AJCC v7

United States
Northwestern University
AVEO Pharmaceuticals, Inc.

Completed

A Phase II Study of Tivozanib in Patients With Metastatic and Non-resectable Soft Tissue Sarcomas

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
National Cancer Institute (NCI)

Completed

Vorinostat and Bortezomib in Treating Patients With Advanced Soft Tissue Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
Washington University School of Medicine
ReVital Cancer Rehabilitation

Terminated

Rehabilitation and Quality of Life Assessment for Soft Tissue Sarcoma Treated With Radiotherapy and Surgery

Soft Tissue Sarcoma

United States
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom

Unknown

HRQoL in Advanced Soft Tissue Sarcoma Patients Treated With Chemotherapy.

Quality of Life

United Kingdom
National Cancer Institute (NCI)

Active, not recruiting

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Histiocytic and Dendritic Cell Neoplasm | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent... and other conditions

United States, Puerto Rico
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

TLR4 Agonist GLA-SE and Radiation Therapy in Treating Patients With Soft Tissue Sarcoma That Is Metastatic or Cannot Be Removed by Surgery

Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
Peking Union Medical College Hospital

Not yet recruiting

Surufatinib and Envafolimab as Second or More-line Therapy in Advanced Soft Tissue Sarcoma Patients

Efficacy and Safety of Surufatinib Combined With Envafolimab as Second or More-line Therapy in Advanced Soft Tissue Sarcoma Patients
National Cancer Institute (NCI)

Completed

Blood and Tissue Study of Patients in NIH Protocol 08-C-0800

Sarcomas

United States
GWT-TUD GmbH
PharmaMar

Completed

Patient Directed Intervention to Improve the Quality of Life for Patients With Soft Tissue Sarcoma (YonLife)

Soft Tissue Sarcoma

Germany
Italian Sarcoma Group
Scandinavian Sarcoma Group; Cooperative Osteosarcoma Study Group

Completed

European Study in Bone Sarcoma Patients Over 40 Years (EUROBOSS)

Osteosarcoma | Spindle Cell Sarcoma of Bone

Italy, Germany, Sweden
Fondazione Policlinico Universitario Campus Bio-Medico
Fondazione Don Carlo Gnocchi Onlus

Recruiting

Clinical Evaluation, Motor Performance and Quality of Life in Patients Affected by Soft Tissue Sarcomas, Undergoing Surgical Treatment: Observational Study (1206)

Sarcoma

Italy
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas

Soft Tissue Sarcoma | Recurrent Soft Tissue Sarcoma | Resectable Soft Tissue Sarcoma

United States
Institut Bergonié
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt...

Recruiting

Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma (TRUST)

Advanced Soft-tissue Sarcoma | Metastatic Soft-tissue Sarcoma

France
National Cancer Institute (NCI)

Completed

Everolimus in Combination With Imatinib Mesylate in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Soft Tissue Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Adult Synovial Sarcoma

United States
Institut Bergonié

Recruiting

Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients (PIPER)

Soft Tissue Sarcoma Adult | Solitary Fibrous Tumors | Hemangioendothelioma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Epithelioid Sarcoma | Desmoplastic Round Cell Tumor

France
Centre Leon Berard

Recruiting

MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma (COTESARC)

Sarcoma,Soft Tissue

France
Xiangya Hospital of Central South University

Active, not recruiting

Efficacy and Safety Study of Cardunilizumab in Soft Tissue Sarcoma

Sarcoma, Soft Tissue

China
Istituto Ortopedico Rizzoli

Completed

Analysis of the Molecular Profile of the Mixofibrosarcoma of the Extremities (MFS)

Sarcoma,Soft Tissue

Italy
Fox Chase Cancer Center

Terminated

Study of TAK-228 (MLN0128) in Soft Tissue Sarcomas

Soft-tissue Sarcoma

United States
Eisai Co., Ltd.

Completed

A Study on Safety and Efficacy in Patients With Soft Tissue Sarcomas (HAL03T)

Sarcoma, Soft Tissue

Japan
Eli Lilly and Company

Completed

A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma

Sarcoma, Soft Tissue

United States
Italian Sarcoma Group

Completed

Retrospective Study of Trabectedin in Soft Tissue Sarcomas (TrObs)

Sarcoma, Soft Tissue

Italy
Institut de Cancérologie de Lorraine

Completed

A Study to Compare Adjuvant Concurrent Chemoradiation (CCRT) to Adjuvant Radiation Therapy (RT) in Grade 2 and 3 Extremity Soft Tissue Sarcomas

Sarcoma,Soft Tissue
University of Michigan Rogel Cancer Center

Completed

Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcoma

Sarcoma, Soft Tissue

United States
GlaxoSmithKline

Completed

Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy (PALETTE)

Sarcoma, Soft Tissue

United States, Australia, Germany, Spain, Belgium, Sweden, France, Korea, Republic of, Italy, Netherlands, Japan, United Kingdom, Denmark
Istituto Clinico Humanitas

Completed

BAY-43-9006 in Advanced, Metastatic Soft Tissue Sarcomas

Sarcoma, Soft Tissue

Italy
David Dickens

Withdrawn

Gemcitabine With Ascorbate Including Adolescents

Soft Tissue Sarcoma | Bone Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft-tissue Sarcoma | Metastatic Bone Sarcoma | Unresectable Bone Sarcoma

United States
Asociación Europea y Latinoamericana SELNET para...

Recruiting

Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc) (SeliSarc)

Sarcoma,Soft Tissue

Spain
University Hospital Heidelberg

Recruiting

Neoadjuvant Irradiation of Retroperitoneal Soft Tissue Sarcoma With Ions Retro-Ion (Retro-Ion)

Sarcoma,Soft Tissue

Germany

Clinical Trials on Refractory Clear Cell Sarcoma of Soft Tissue

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