Clinical Trials on Refractory Malignant Neoplasm of Multiple Primary Sites in Italy

Total 1347 results

Regina Elena Cancer Institute
Azienda Policlinico Umberto I; San Giovanni Addolorata Hospital

Recruiting

Quality of Life and Voice Perception in Patients Laryngoctomized Phonatory Wearers

Quality of Life | Larynx Cancer

Italy
Istituto Ortopedico Galeazzi

Not yet recruiting

The Bone-parathyroid Crosstalk in Primary Hyperparathyroidism (PARABONE)

Hyperparathyroidism, Primary | Osteoporosis | Parathyroid Neoplasms

Italy
Sergiusz Jozwiak
Medical University of Vienna; Charite University, Berlin, Germany; Institut National... and other collaborators

Unknown

Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex (EPISTOP)

Epilepsy | Tuberous Sclerosis Complex | TSC

Poland, Austria, Belgium, Czech Republic, France, Germany, Italy, Netherlands
Humanitas Clinical and Research Center

Completed

Study on the Quality of Life (QoL) After Liver Surgery

Quality of Life | Cholangiocarcinoma | Hepatocarcinoma

Italy
National Cancer Institute, Naples

Recruiting

Active Surveillance Versus Surgery in Thyroid Papillary Microcarcinoma (MITICA)

Papillary Microcarcinoma of the Thyroid

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Recruiting

The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study. (ITCMicroUtCa)

Cervical Cancer | Endometrial Neoplasms | Endometrial Cancer | Sentinel Lymph Node | Lymph Node Disease | Lymph Node Metastases | Sentinel Lymph Node Biopsy | Endometrium Tumor | Cervical Neoplasm | Micrometastasis | Cervical Tumor

Italy
IRCCS Policlinico S. Matteo

Withdrawn

High Cut-off Hemodialysis in Patients With Advanced Cardiac AL Amyloidosis and End Stage Renal Disease (DIACAL)

Primary Amyloidosis of Light Chain Type

Italy
Centro di Riferimento Oncologico - Aviano

Not yet recruiting

The Impact of Adverse Events, Produced by Antibodies Conjugates, on Quality of Life in Patients With Metastatic Breast Cancer: Multicentric, Observational Study (EVA). (EVA)

Metastatic Breast Cancer

Italy
Novartis Pharmaceuticals

Terminated

This Was an Open-label, Single-arm Extension Study (CFTY720D2306E1) to a Double-blind, Randomized Multicenter, Placebo-controlled, Parallel-group Core Study (CFTY720D2306) in PPMS. (INFORMS)

Primary Progressive Multiple Sclerosis

United States, Belgium, Poland, Germany, Hungary, Turkey, Spain, Australia, Canada, Czechia, Switzerland, United Kingdom, Netherlands, France, Italy, Denmark, Finland, Sweden
Centro di Riferimento Oncologico - Aviano

Recruiting

Study for Validation of Target Therapy in Multiple Myeloma Cells From Patients With miRNAs Released From B Cells, and Study of the Bone Marrow Tumor Microenvironment (Microenvironment of MM)

Multiple Myeloma

Italy
ITEL Telecomunicazioni Srl
Advice Pharma Group srl

Active, not recruiting

Prospective Comparative Study for Patients With Biochemical Recurrence Prostate Cancer Detecting by 18F-JK-PSMA-7 (MIP7)

Prostate Cancer | Radiotherapy | Prostatectomy | 18F- Fluorocholine | PSMA PET | Tumor of Prostate

Italy
Regina Elena Cancer Institute

Completed

Evaluating the Role of Both PSMA and 64Cu-PET/CT Total Body in Patients With Locally Relapsed Prostate Cancer

Prostate Neoplasms

Italy
Eli Lilly and Company

Completed

Intravesical Gemcitabine Instillation Followed by Transurethral Resection for the Treatment of Patients With Superficial Bladder Cancer at Low Risk.

Superficial Bladder Cancer

Italy
IRCCS San Raffaele
High Research

Recruiting

Sacituzumab Govitecan, Preceding Radical Cystectomy, in Treating Patients With Muscle-invasive Bladder Cancer

Urothelial Carcinoma

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...
University of Campania "Luigi Vanvitelli"; Istituti Ospitalieri di Cremona; Istituto... and other collaborators

Recruiting

APOLLO 11, Consortium of Italian Centers Involved in Treatment of Patients With Lung Cancer Treated With Innovative Therapies: Real World Data and Translational Reaserch

Cancer | NSCLC | Lung Cancer | Adenocarcinoma of Lung | Squamous Cell Lung Cancer

Italy
Sanofi

Active, not recruiting

Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (HERCULES)

Secondary Progressive Multiple Sclerosis

United States, Argentina, Belgium, Canada, Czechia, France, Germany, Greece, India, Israel, Netherlands, Norway, Portugal, Turkey, United Kingdom, Japan, Austria, Bulgaria, China, Denmark, Finland, Italy, Lithuania, Poland, Romania, Russian... and more
MedImmune LLC

Active, not recruiting

Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Subjects With Unresectable Malignant Mesothelioma (Tremelimumab)

Unresectable Pleural or Peritoneal Malignant Mesothelioma

United States, Italy, Spain, United Kingdom, Belgium, Canada, Poland, France, Korea, Republic of, Hungary, Russian Federation, Germany, Australia, South Africa, Netherlands, Romania, Sweden, Israel, Denmark
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer

Clear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Lymphoblastic Lymphoma | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Childhood Acute... and other conditions

United States, Germany, Italy
Tethis S.p.A.

Recruiting

Identification of Prostate Cancer Specific Markers in Patients Compared to Healthy Participants

Prostatic Neoplasms

Italy
Ospedale Regina Montis Regalis
Azienda Ospedaliera Città della Salute e della Scienza di Torino; Ministry... and other collaborators

Recruiting

ERAS (Enhanced Recovery After Surgery) Protocol Implementation in Piedmont Region for Hysterectomy. (ERAS-Gyneco)

Uterine Neoplasms

Italy
Istituto Clinico Humanitas

Recruiting

PSMA PET/CT vs. mpMRI in Patients With a High Suspicion of Prostate Cancer: a Head to Head, Parallel, Prospective Trial (PROSPET-BX)

Prostate Cancer

Italy
IRCCS San Raffaele
Giorgio Gandalgia; Alberto Briganti; Vito Cucchiara

Not yet recruiting

Phase 2 Study of Neoadjuvant PEMbrolizumab Before Radical PROstatectomy in High-risk Prostate Cancer Patients (PEM-PRO)

Prostate Cancer

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

A Phase II Study Evaluating the Efficacy of Enzalutamide and the Role of ARv7 in Metastatic Castration Resistant Prostate Cancer (mCRPC) Patients With Visceral Disease. (EXCALIBUR)

Carcinoma Prostate

Italy
Azienda Socio Sanitaria Territoriale degli Spedali...

Unknown

Outcomes From a RCT Comparing Preventive Versus Delayed Ligation of DVC During Robot-assisted Radical Prostatectomy

Prostate Cancer

Italy
University of Roma La Sapienza

Completed

MR-guided Focused Ultrasound Treatment of Prostate Cancer: Focal Therapy for Locally Non-Advanced Disease

Prostate Cancer

Italy
Novartis

Completed

Effects of Octreotide Acetate on Circulating Levels of Chromogranin A in Advanced Prostate Cancer Patients

Prostate Cancer

Italy
Italian Trial in Medical Oncology

Completed

Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer (P1)

Prostate Cancer

Italy
Italian Trial in Medical Oncology

Completed

Study Comparing Association Between Sorafenib and Interleukin-2 (IL-2) Versus Sorafenib in 1st Line Therapy in Advanced (Adv) Renal Cell Carcinoma (RCC) (ROSORC)

Renal Cell Carcinoma | Metastatic Disease

Italy
University of Roma La Sapienza
Andrea Laghi

Active, not recruiting

Radiomics and Molecular Expression Predictive Model for Esophago-Gastric Junction and Gastric Cancer TRG

Gastric Cancer | Adenocarcinoma of the Stomach

Italy, Netherlands
University Hospital of Ferrara

Unknown

Radioguided Selective Neck Dissection for Staging and Treatment of Oral Cavity and Oropharyngeal Squamous Cell Carcinoma

Oropharyngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

Italy
University of Turin, Italy

Completed

Ipsilateral and Contralateral Index for the Interpretation of Adrenal Vein Sampling (AVS) in Primary Aldosteronism

Primary Aldosteronism | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)

Italy
Paolo Puppo

Completed

Prospective Randomized Comparison of Transurethral Resection by Mean of White Light and Narrow Band Imaging

Non Muscle Invasive Bladder Cancer

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Hysteroscopic vs. Cervical Injection for Sentinel Node Detection of Endometrial Cancer (SLN_EC)

Endometrial Cancer

Italy
Azienda Ospedaliera San Giovanni Battista
Centro di Riferimento per l'Epidemiologia e la Prev. Oncologica Piemonte; Rete...

Unknown

Trial Between Two Follow up Regimens With Different Test Intensity in Endometrial Cancer Treated Patients (TOTEM)

Endometrial Cancer

Italy
Catholic University of the Sacred Heart

Unknown

Role of Uterine Manipulator in Hysterectomy - Ro.Man.HY (RoManHy)

Endometrial Cancer

Italy
Catholic University of the Sacred Heart
Fanfani, Francesco, M.D.; Fagotti, Anna, M.D.

Completed

2D Versus 3D Radical Laparoscopic Hysterectomy for Endometrial Cancer: a Prospective Randomized Trial

Endometrial Cancer

Italy
Catholic University of the Sacred Heart

Unknown

Thunderbeat Technology vs Standard Bipolar Electro-surgery in Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for Endometrial Cancer (Thunder Endom)

Endometrial Cancer

Italy
IRCCS San Raffaele

Recruiting

Study on the Occurrence of Possible Relapses and on the Quality of Life in Patients Who Underwent TURBK.

Bladder Cancer | Bladder Disease | Bladder Cancer Recurrent | Bladder Urothelial Carcinoma | Non Muscle Invasive Bladder Cancer | Bladder Neoplasm | Non-Muscle Invasive Bladder Urothelial Carcinoma | Non-Muscle Invasive Bladder Neoplasms | Bladder Cancer Stage I, With Cancer in Situ | Bladder Urothelial... and other conditions

Italy
Ciceri Fabio

Completed

Phase II Trial in Elderly Patients With AML or MDS in Complete Remission Not Eligible for Allogenic Transplant (FLAT-Auto)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Transplant-Related Hematologic Malignancy

Italy
Morphotek

Terminated

Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM) (ARTEMIS)

Mesothelioma, Malignant

France, United Kingdom, United States, Germany, Australia, Italy
CNAO National Center of Oncological Hadrontherapy
Foundation IRCCS San Matteo Hospital

Recruiting

Carbon Ions Radiation Therapy for Resectable or Borderline Resectable Pancreas Adenocarcinoma (PIOPPO)

Pancreas Adenocarcinoma | Resectable Pancreatic Cancer | Cancer of Pancreas

Italy
National Cancer Institute (NCI)

Completed

Acetylsalicylic Acid Compared to Placebo in Treating High-Risk Patients With Subsolid Lung Nodules

Current Smoker | Former Smoker | Multiple Pulmonary Nodules | Tobacco Use Disorder

United States, Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
National Research Council

Recruiting

Using Tissue-based Spatial Data to Understand How Obesity-related Tumor Metabolites Fuel Prostate Cancer Progression (OBESITA'&PCa)

Obesity | Prostate Cancer | Prostate Adenocarcinoma | Prostate Neoplasm | Prostatic Neoplasm

Italy
Fondazione Don Carlo Gnocchi Onlus

Completed

Preventing Falls and Participation Restrictions in Neurological Diseases

Stroke | Multiple Sclerosis | Parkinson Disease

Italy
Fondazione Don Carlo Gnocchi Onlus

Unknown

Improving Dynamic Balance and Gait Adaptability Using Treadmill Training

Stroke | Multiple Sclerosis | Parkinson Disease

Italy
IRCCS San Raffaele
IBFM-CNR (Istituto di Bioimmagini e Fisiologia Molecolare, National Research...

Completed

MR Radiomic Features in Prostate Cancer

Prostate Cancer

Italy
IRCCS San Raffaele

Completed

Early DVC Ligation and Urinary Continence Recovery After RARP

Prostate Cancer

Italy
Fondazione del Piemonte per l'Oncologia
Università degli Studi di Trento; Ospedale Santa Croce-Carle Cuneo

Recruiting

The Effect of Prebiotic Inulin on Patients Affected by R/M HNSCC Treated With Immune Checkpoint Inhibitors (PRINCESS)

Head and Neck Squamous Cell Carcinoma

Italy
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Recruiting

Transforming Rehabilitation: Personalised Care for a Better Quality of Life (PREPARE)

Osteoarthritis, Knee | Osteoarthritis, Hip | Osteoarthritis Secondary | Osteoarthritis Primary

Italy
Regina Elena Cancer Institute
Azienda Sanitaria-Universitaria Integrata di Udine; San Giovanni Addolorata...

Recruiting

A Phase I-II Study on Stereotactic Body Radiotherapy in 3 Fractions for Low/Int Risk Prostate Cancer (eHYPO)

Prostate Cancer

Italy

Clinical Trials on Refractory Malignant Neoplasm of Multiple Primary Sites in Italy

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