Clinical Trials on Renal Function Disorder in United States

Total 64852 results

Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Vitae Pharmaceuticals, Inc.
Brigham and Women's Hospital

Completed

Direct Renin Inhibition and the Kidney

Renal Function

United States
VA Office of Research and Development

Active, not recruiting

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

Cognitive Function | Functional Status

United States
Stanford University

Completed

Perioperative Aminophylline to Improve Early Kidney Function After a Kidney Transplant (RTphylline)

Function of Renal Transplant

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Allergan

Completed

Study of Ulipristal Acetate in Female Patients With Moderately or Severely Impaired Renal Function, Compared With Matched Healthy Female Subjects

Renal Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
University of California, San Diego

Completed

Renal Effects of Hormones/Biomarkers in Transgender PrEP Recipients

Hormone Replacement Therapy | Renal Function | Transgender

United States
Schroppel, Bernd, M.D.
Alexion Pharmaceuticals

Terminated

A Study of the Activity of Eculizumab for Prevention of Delayed Graft Function In Deceased Donor Kidney Transplant

Delayed Function of Renal Transplant

United States
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Astellas Pharma Europe Ltd.

Unknown

RituxiMab INDuction in Renal Transplantation (ReMIND)

Function of Renal Transplant

United Kingdom
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function (MODERATE)

Obesity | Overweight | Blood Pressure | Renal Function | Endothelial Function

United States
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Renal Impairment

United States
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Renal Function

Impaired Renal Function

United States
NicOx

Completed

A Pharmacokinetics and Safety Study of Naproxcinod in Subjects With Impaired Renal Function (HCT3012-X-106)

Renal Failure

United States
Eloxx Pharmaceuticals, Inc.
Syneos Health

Completed

A Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics of ELX-02

Impaired Renal Function

United States
Shire

Completed

Study of SSP-004184 (FBS0701) in Healthy Adults and Elderly Subjects and in Subjects With Impaired Renal Function

Impaired Renal Function

United States
Exelixis

Completed

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Healthy | Renal Impairment

United States
Auburn University

Recruiting

The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function (MAVHS)

Blood Pressure | Cardiovascular Risk Factor | Renal Function | Racial Disparities

United States
Gilead Sciences

Completed

Pharmacokinetics of Lanraplenib in Adults With Impaired Renal Function

Inflammatory Disease

United States, New Zealand, Germany
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

The Safety and Pharmacokinetics of Carbavance™ (RPX2014/RPX7009) in Subjects With Renal Insufficiency

Subjects With Varying Degrees of Renal Insufficiency and | Subjects With Normal Renal Function

United States
University of Edinburgh
Kidney Cancer UK

Terminated

Heme Arginate in Transplantation Study (HOT2)

Renal Transplant Rejection | Renal Transplant Failure

United Kingdom
GlaxoSmithKline

Completed

A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function

Solid Tumours

United States, Korea, Republic of, Netherlands
Prolong Pharmaceuticals

Completed

Efficacy and Safety of SANGUINATE™ for Reduction of Delayed Graft Function in Patients Receiving a Kidney Transplant

Delayed Function of Renal Transplant

United States
Bayer

Completed

A Study to Evaluate the Pharmacokinetics (How it Moves Into, Through and Out From the Body) of a New Gadolinium-based Contrast Agent (GBCA) After Injection and How Safe it is in Participants With Normal and Impaired Renal Function

Contrast Enhancement in Magnetic Resonance Imaging

United States
Amgen

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function

Heart Failure

United States
Gilead Sciences

Completed

Pharmacokinetics of Bictegravir in Adults With Normal and Impaired Renal Function

HIV

United States, New Zealand
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.

Renal Function | Liver Transplant

United States, Germany, Spain, Belgium, France, Hungary, Australia, Sweden, Italy, Canada, United Kingdom, Denmark
Repros Therapeutics Inc.

Completed

Evaluation of Pharmacokinetic and Safety Profile of Androxal in Male Subjects With Impaired Renal Function

Secondary Hypogonadism

United States
University of Wisconsin, Madison
Bristol-Myers Squibb

Withdrawn

Belatacept in Kidney Transplantation of Moderately Sensitized Patients (BelatPilot)

End Stage Renal Disease | Antibody Mediated Rejection

United States
Bayer

Completed

Study to Develop a Tool to Estimate the Kidney Function in Databases Without Laboratory Data

Renal Function

United States
Eisai Inc.

Completed

An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Impaired Renal Function

Unspecified Adult Solid Tumor, Protocol Specific

United States
University of California, San Francisco
California Transplant Donor Network

Completed

The Effect of Therapeutic Hypothermia on Deceased Donor Renal Graft Outcomes - a Randomized Controlled Trial From the Region 5 Donor Management Goals Workgroup

Renal Function | Mild Hypothermia | Deceased Organ Donor

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Severe Renal Impairment on Gilteritinib Compared to Healthy Participants With Normal Renal Function

Renal Impaired | Gilteritinib | Normal Renal Function | Pharmacokinetics of ASP2215

United States, Bulgaria
Genzyme, a Sanofi Company

Completed

An Open-label, Prospective, Randomized, Multi-center, Phase II Comparative Trial of Thymoglobulin Versus Simulect for the Prevention of Delayed Graft Function and Acute Allograft Rejection in Renal Allograft Recipients.

Cadaveric Donor Renal Transplantation | Acute Renal Allograft Rejection | Induction Therapy

United States, France, Spain, United Kingdom, Germany
University of Illinois at Chicago
National Institute on Aging (NIA); Midwest Roybal Center for Health Promotion...

Completed

Exercise Training and Cognitive Function in Kidney Disease

Chronic Kidney Diseases | Older Adults | Cognitive Function, Preclinical

United States
University of Miami
Standard Process Inc.

Completed

Evaluating Whole Foods Supplementation on Cognition

Sub-optimal Cognitive Function | Sub-optimal Immune Function

United States
PhaseBio Pharmaceuticals Inc.

Completed

Pharmacokinetic, Safety/Tolerability Study of a Single SC Dose of PB1023 Injection in Subjects With Normal and Impaired Renal Function

Diabetes Mellitus, Type 2

United States
Novartis Pharmaceuticals

Completed

Study of the Safety, Tolerability, and Pharmacokinetics of LHW090 in Patients With Moderately Impaired Renal Function (LHW090)

Chronic Kidney Disease (CKD)

Germany, United States
American Regent, Inc.

Completed

Evaluation of Efficacy and Safety of Ferric Carboxymaltose (FCM) in Patients With Iron Deficiency Anemia and Impaired Renal Function (REPAIR-IDA)

Iron Deficiency Anemia | Impaired Renal Function

United States
Imperial College London

Completed

Effects of Obesity Surgery on Renal Function

Impaired Renal Function

United Kingdom
Novartis Pharmaceuticals

Terminated

A Dose-escalation Pharmacokinetic Study of Intravenous ASA404 in Adult Advanced Cancer Patients With Impaired Renal Function and Patients With Normal Renal Function

Metastatic Cancer

United States
Duquesne University
Pennsylvania Department of Health

Completed

Project for Cognitive Advancement in Infants With Neuromotor Disorders (CAN-Do)

Motor Coordination or Function; Developmental Disorder

United States
George Washington University
Boehringer Ingelheim

Completed

Linagliptin's Effect on CD34+ Stem Cells

Type 2 Diabetes | Impaired Renal Function

United States
Virginia Commonwealth University

Completed

A Multiple Baseline Design Study to Investigate the Effectiveness of OT-SI Using an Intensive Intervention Model

Motor Coordination or Function; Developmental Disorder

United States
Amazentis SA
University of Washington; Synteract, Inc.

Completed

Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)

Aging | Muscle Function | Mitochondrial Function, Bioenergetics

United States
Columbia University
National Institute on Aging (NIA)

Terminated

Cognitive Control and Physical Exercise

Cognitive Function | Day-to-Day Function

United States
Northwestern University
National Heart, Lung, and Blood Institute (NHLBI); American Society for Transplantation

Withdrawn

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

High Blood Pressure | Liver Transplant | Renal Function Abnormal

United States
University of Florida
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Curcumin and Function in Older Adults (SPICE)

Cognitive Function | Older Adults | Physical Function

United States
University of Virginia
Child Neurology Foundation

Recruiting

Tremor Retrainer Software Application for Functional Tremor

Functional Neurological Symptom Disorder | Functional Neurological Disorder | Functional Movement Disorder

United States

Clinical Trials on Renal Function Disorder in United States

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