Clinical Trials on Renal Function Impairment in Czechia

Total 283 results

Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Healthy Subjects | Severe Renal Impairment

Czechia
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of Buparlisib in Subjects With Renal Impairment.

Renal Impairment

Czechia, Germany, Romania, Bulgaria
Takeda

Completed

A Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics (PK) of a Single Intravenous (IV) TAK-954

Renal Impairment | Healthy Volunteers

Czechia, Hungary
Oncopeptides AB

Terminated

PK of Melphalan During Treatment With Melflufen and Dexamethasone in Patients With RRMM and Impaired Renal Function (BRIDGE)

Multiple Myeloma | Renal Impairment

Greece, Czechia, Poland
Bristol-Myers Squibb

Completed

A Study to Assess the Safety of Experimental Medication BMS986165 in Participants With Normal Kidney Function and Participants With Mild to End-Stage Kidney Disease.

Renal Impairment | Healthy Volunteer

United States, Czechia, Hungary, Poland
Novartis

Completed

Effect of Severe Renal Impairment on Pharmacokinetics and Metabolism of a Single Administration of Licarbazepine

Healthy

Czech Republic
University of Ostrava

Completed

The Effect of Transcutaneous Vagus Nerve Stimulation on Cognitive Function

Cognitive Function

Czechia
GlaxoSmithKline

Completed

Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment

Pulmonary Disease, Chronic Obstructive

Czechia, Hungary
Novo Nordisk A/S

Completed

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal Function

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Hungary, Czechia
University Hospital Ostrava

Not yet recruiting

Determination of Drug Levels for Pharmacotherapy of Heart Failure

Cardiovascular Diseases | Heart Failure With Reduced Ejection Fraction

Czechia
Boehringer Ingelheim

Completed

Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate

Arthroplasty, Replacement | Prevention of Venous Thromboembolism | Moderate Renal Impairment (CrCl 30-50 mL/Min)

Austria, Canada, Czechia, Finland, Netherlands, Sweden
FORUM Pharmaceuticals Inc
PRA Health Sciences

Completed

EVP-6124 Renal Impairment Study

Renal Impairment

Czech Republic, Hungary
Taiho Oncology, Inc.

Completed

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

Advanced Solid Tumors

United States, Czechia, Serbia
Masaryk Hospital Krajská zdravotní a.s.

Completed

Effect of Midazolam and Dexmedetomidine on Heart Function - A Randomized MRI-based Study. (MRI)

Magnetic Resonance Imaging | Sedation | Cardiac Function

Czechia
LEO Pharma

Completed

Innohep® in Elderly Patients With Impaired Renal Function Treated for Acute Deep Vein Thrombosis

Deep Vein Thrombosis

Bulgaria, Croatia, Czechia, France, Germany, Poland, Romania, Serbia, Spain
Astellas Pharma Inc

Completed

Renal Impairment Study With ASP1941

Type 2 Diabetes Mellitus

Hungary, Poland, Czechia, Slovakia
Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
Hoffmann-La Roche

Completed

Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib

Hepatic Impairment

Czechia, Slovakia
Charles University, Czech Republic

Recruiting

PAPSY - Memory in Psychiatry (PAPSY)

Cognitive Impairment

Czechia
Masaryk University
St. Anne's University Hospital Brno, Czech Republic

Completed

The Effect of Transcranial Direct Current Stimulation on Visual Attention in Mild Cognitive Impairment

Mild Cognitive Impairment

Czechia
Fresenius Kabi
EastHORN Clinical Services in CEE; MLM Medical Labs GmbH; ALS Czech Republic,... and other collaborators

Completed

Short-term Metabolic Effects of Ketosteril® Supplemented Low Protein Diet in Pre-dialysis Chronic Kidney Disease (CKD) Patients (CKD)

Renal Insufficiency, Chronic

Czechia
Masaryk University
Swiss Federal Institute of Technology

Recruiting

Novel, Individualized Brain Stimulation, Network-based Approaches to Improve Cognition (NiBS-iCog)

Healthy Aging | Mild Cognitive Impairment

Czechia
Takeda

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Healthy Volunteers | Hepatic Impairment

Czechia, Slovakia
Charles University, Czech Republic

Recruiting

PAMNEU - Memory in Neurology

Cognitive Impairment

Czechia
National Institute of Mental Health, Czech Republic

Completed

Ecologically Valid Virtual Tasks vs Paper-pencil Methods in Cognitive Rehabilitation in Patients With Schizophrenia and Depression

Depression | Schizophrenia | Cognitive Impairment

Czechia
Daiichi Sankyo, Inc.
PRA Health Sciences

Completed

Pilot PK/PD Study of DS-1093a in Patients With Chronic Kidney Disease

Chronic Renal Disease | Renal Anemia

Czechia, Hungary
Charles University, Czech Republic
University Hospital Vinohrady; Faculty of Physical Education and Sport

Recruiting

The Effect of Tai Chi and Therapy by Dance and Movement on Blood Irisin Levels in Older Adults Over 65 Years of Age.

Physical Activity | Cognitive Impairment | Aging | Mood Change | Memory Deficits

Czechia
Hoffmann-La Roche

Completed

An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Chronic Kidney Disease Not On Dialysis

Kidney Disease, Chronic

Czechia
Pfizer

Completed

Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States, Belgium, Czechia, Slovakia
GlaxoSmithKline

Completed

A Study to Assess the Effects of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Mild, Moderate or Severe Hepatic Impairment.

Asthma

Czechia, Slovakia
Masaryk University
St. Anne's University Hospital Brno, Czech Republic

Unknown

Modulation of Cognition and Brain Connectivity by Noninvasive Brain Stimulation in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease (LUSTR)

Mild Cognitive Impairment

Czechia
University Hospital Hradec Kralove

Completed

The Effect of Blood Pressure on the Postoperative Cognitive Dysfunction

Mild Cognitive Impairment

Czechia
University Hospital Hradec Kralove

Terminated

The Effect of Nimodipine on the Postoperative Cognitive Dysfunction

Mild Cognitive Impairment

Czechia
Solvay Pharmaceuticals
Quintiles, Inc.

Terminated

Study to Evaluate the Effect of SLV320 in Addition to Chronic Furosemide Treatment on Renal Function in Subjects With Congestive Heart Failure and Impaired Renal Function

Congestive Heart Failure

United States, Argentina, Belgium, Czech Republic, Former Serbia and Montenegro, Germany, Poland, Russian Federation, South Africa, Spain
Pfizer

Completed

A STUDY TO COMPARE THE PHARMACOKINETICS OF PF-06835919 IN PARTICIPANTS WITH AND WITHOUT HEPATIC IMPAIRMENT

Hepatic Impairment | Healthy Participants

Czechia, Slovakia, Belgium
Noblewell
Coridea; Axon Therapies

Completed

Surgical Resection of the Greater Splanchnic Nerve in Subjects Having Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction

Czechia, Poland
Axon Therapies, Inc.

Enrolling by invitation

Endovascular GSN Ablation in Subjects With HFpEF

Heart Failure With Preserved Ejection Fraction

Czechia, Georgia
Charles University, Czech Republic
University Hospital Ostrava; Brno University Hospital; Regional Hospital Liberec and other collaborators

Not yet recruiting

Pulsed-field Ablation for Patients With Asymptomatic Non-paroxysmal Atrial Fibrillation

Atrial Fibrillation | Pulsed-field Ablation | Functional Exercise Testing

Czechia
Mardil Medical

Unknown

Evaluation of the Minimally Invasive VenTouch™ System in the Treatment of Functional Mitral Valve Regurgitation (FMR)

Functional Mitral Regurgitation

Czechia, France
National Cancer Institute (NCI)

Completed

Follow-Up Study of Kidney Cancer Patients

Renal Cancer

Czechia, Poland
Oslo University Hospital
South-Eastern Norway Regional Health Authority

Unknown

Global Strain and Mechanical Dispersion May Predict Death and Ventricular Arrhythmias Better Than Ejection Fraction

Left Ventricular Function Systolic Dysfunction

Norway, Czechia
Bristol-Myers Squibb

Completed

A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function

Renal Failure | Congestive Heart Failure | Kidney Failure | Cardiac Failure | Myocardial Failure

Poland, Czechia
Fresenius Medical Care Deutschland GmbH
Institut Dr. Schauerte GmbH (IDS)

Completed

Comparison of Clinical Performance and Hemocompatibility of Dialyzers Applied During Post-dilution Online Hemodiafiltration (eMPORAIII)

Renal Failure | End Stage Renal Disease

Germany, Czechia, Hungary
Masaryk University
St. Anne's University Hospital Brno, Czech Republic

Not yet recruiting

Noninvasive Temporal Interference Stimulation: Modulating Associative Memory by Targeting Deep-brain Targets (Deep-HiPs)

Alzheimer Disease | Healthy Aging | Mild Cognitive Impairment | Memory Disorders in Old Age

Czechia
Institute for Clinical and Experimental Medicine

Active, not recruiting

Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines Against COVID-19 in Kidney Transplant Recipients.

COVID-19 | Kidney Diseases | Vaccine Adverse Reaction | Kidney Transplant; Complications | Rejection Acute Renal | Rejection Chronic Renal

Czechia
Vertex Pharmaceuticals Incorporated

Completed

Study of Lumacaftor in Combination With Ivacaftor in Subjects With Moderate Hepatic Impairment and Healthy Subjects

Healthy | Hepatic Impairment

Slovakia, Czech Republic
AstraZeneca
PRA Health Sciences

Completed

Pharmacokinetics, Safety & Tolerability of ZD4054 (Zibotentan) in Subjects With Normal, Mild, Moderate and Severe Hepatic Impairment

Hepatic Impairment

Czech Republic
Thomayer University Hospital
Charles University, Czech Republic

Completed

Faecal Microbiota Transplantation in Irritable Bowel Syndrome (MISCEAT)

Irritable Bowel Syndrome With Diarrhea | Irritable Bowel Syndrome Mixed

Czechia

Clinical Trials on Renal Function Impairment in Czechia

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