Clinical Trials on Renal Function Impairment in Healthy Volunteers

Total 193 results

Achaogen, Inc.
Department of Health and Human Services

Completed

A Study to Evaluate the Effect of IV ACHN-490 Injection on the QT/QTc Interval in Healthy Volunteers

Cardiac Effects in Normal Healthy Volunteers

United States
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Healthy Volunteers | Moderate Hepatic Impairment | Severe Hepatic Impairment

United States
Annexon, Inc.

Terminated

Single Dose Study of ANX005 in Healthy Volunteers

Safety and Tolerability in Healthy Volunteers

Australia
Neuraly, Inc.

Completed

A Phase 1 Study to Assess the Safety of NLY01 in Healthy Subjects (NLY01-H1)

Safety and Tolerability in Healthy Volunteers

United States
Charles Berde

Completed

Safety Study of Long-Acting Local Anesthetic

Safety of Neosaxitoxin in Healthy Volunteers

United States
University Hospital, Basel, Switzerland

Completed

RAS-Peptide-Profile Study in Healthy Male Subjects (RAS)

RAS Peptide Profile in Healthy Volunteers

Switzerland
University of Edinburgh
Umeå University; NHS Lothian

Completed

Diesel Exhaust Inhalation, Systemic Nitric Oxide Inhibition and Cardiac Output (DISCO)

Vascular Function in Healthy Volunteers

Sweden
Mitsubishi Tanabe Pharma America Inc.

Completed

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Renal Impairment | Normal Renal Function

Germany
Novartis Pharmaceuticals

Completed

Pharmacokinetics Study of Asciminib in Subjects With Impaired Renal Function Compared to Matched Healthy Volunteers

Renal Impairment

Germany, Bulgaria
Drugs for Neglected Diseases
Sanofi

Completed

Fexinidazole (1200mg) Bioavailability Under Different Food Intake Conditions

PK in Healthy Volunteers

France
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Renal Impairment

United States
Cingulate Therapeutics

Completed

Fed-Fast Crossover Study to Assess the Effect of Food With CTx-1301 in Healthy Subjects (Fed-Fast)

Healthy Volunteers in Fed and Fasted State

United States
Pyramid Biosciences

Completed

A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200

Absorption, Metabolism and Excretion in Healthy Volunteers

United States
University of California, San Diego

Completed

Effects of Catheter Tip Location Relative to the Femoral Nerve on Sensory and Motor Function

Continuous Femoral Nerve Blocks in Healthy Volunteers

United States
University of Nebraska
National Institute of Mental Health (NIMH)

Completed

Modulation of Spontaneous Cortical Activity by tDCS: BRAIN Initiative I

How Occipital tDCS Affects Brain Function in Healthy Adults

United States
Takeda

Recruiting

A Study of TAK-279 in Adults With or Without Liver Damage

Healthy Volunteers | Hepatic Impairment

United States
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Completed

GP681 in Volunteers With Hepatic Impairment Compared With Healthy Volunteers

Healthy Volunteers | Hepatic Impairment

China
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed in People With Liver Dysfunction

Healthy Volunteers | Hepatic Impairment

United States
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

A Pharmacokinetics and Tolerability Study of Fedratinib in Subjects With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Brown University
National Institute of Mental Health (NIMH)

Recruiting

Cognitive Control & the Functional Organization of the Frontal Cortex

Healthy Volunteers | Executive Function | Multitasking Behavior and Neural Representations Associated With Multitasking Ability

United States
Bristol-Myers Squibb

Recruiting

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function

Healthy Volunteers | Hepatic Impairment

United States
Celgene

Completed

Evaluate the Pharmacokinetics of CC-220 in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared With Healthy Subjects

Healthy Volunteers | Hepatic Impairment

United States
Bayer

Completed

A Study to Learn More About the Safety and the Blood Level of BAY1747846 Given as Injection Into the Vein at Increasing Single Doses in Chinese Healthy Male Participants

Healthy Volunteers | Contrast Enhancement in Magnetic Resonance Imaging

China
Bayer

Completed

A Study to Learn More About the Safety and the Level of BAY 1747846 in Body Given as Injection Into the Vein at Increasing Single Doses in Japanese Healthy Male Participants

Healthy Volunteers | Contrast Enhancement in Magnetic Resonance Imaging

Japan
Pyramid Biosciences

Completed

A Formulation Bridging and Food Effect Study of PBI-200 in Healthy Volunteers

Formulation Bridging and Food Effect in Healthy Volunteers

United States
Central South University

Completed

Drug Interaction Study of Olmesartan in Healthy Chinese Volunteers

Drug Interaction of Olmesartan in Healthy Chinese Volunteers

China
Pfizer

Completed

STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT

Healthy Volunteers | Hepatic Impairment

United States
Takeda

Completed

A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

United States, Hungary
Takeda

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Healthy Volunteers | Hepatic Impairment

Czechia, Slovakia
JW Pharmaceutical

Completed

A Safety, PK, PD and Food Effect Study of URC102 in Healthy Adults and Patients With Renal Impairment

Healthy, Renal Impairment

Korea, Republic of
Teva takeda

Completed

A Study of TAK-279 in Adults With or Without Kidney Problems

Renal Impairment | Healthy Volunteers

United States
Astellas Pharma Global Development, Inc.

Completed

A Study About How ASP5354 Affects the Body in Healthy Adults and in Adults Whose Kidneys do Not Work Well

Renal Impairment | Healthy Volunteers

United States, Japan
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Renal Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Renal Function

Renal Impairment | Healthy Volunteers

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study of Mobocertinib Capsules in People With Severe Kidney Problems and People With Healthy Kidneys

Renal Impairment | Healthy Volunteers

United States
Dexa Medica Group

Completed

Bioequivalence Study of 4 mg Glimepiride Tablet

Glimepiride BE Study in Healthy Volunteers Under Fasting Condition

Indonesia
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study to Evaluate the Pharmacokinetics of Apatinib in Subjects With Impaired Renal Function

Subjects With Impaired Renal Function and Healthy Subjects
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
National Central University

Completed

Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.

Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function

Taiwan
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Healthy Subjects | Severe Renal Impairment

Czechia
Celgene

Completed

A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult Subjects (AME/FE)

Safety and Pharmacokinetics in Healthy Volunteer Subjects

United States
Isofol Medical AB

Completed

Study Evaluating ECG Effects, Safety, Tolerability and Pharmacokinetics of Single Doses of Modufolin (Arfolitixorin) in Healthy Volunteers Tetrahydrofolate in Healthy Male Volunteers

Phase I Study in Healthy Volunteers to Evaluate ECG Effect

Sweden
The Medicines Company

Completed

Appraisal of MDCO-157 and Plavix® Pharmacokinetics and Pharmacodynamics in Healthy Volunteers With an Evaluation (AMPHORE)

Pharmacokinetics and Pharmacodynamics in Healthy Volunteers

France
Pfizer

Completed

Renal Impairment Study of PF-06700841

Renal Impairment | Healthy Volunteer

United States
Clinuvel (UK) Ltd.

Completed

DNA Repair Capacity of Afamelanotide on Ultraviolet Radiation-induced DNA Damage in Healthy Volunteers

Afamelanotide Evaluated as Skin DNA Repair Therapy in Healthy Volunteers

United Kingdom
Pfizer

Completed

Effect Of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of PF-06865571 In Subjects With Hepatic Impairment and in Healthy Subjects

Healthy Volunteers | Hepatic Impairment

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study of the Pharmacokinetics of Isavuconazole in Healthy Non-Elderly and Elderly Male and Female Subjects

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Safety and Tolerability in Elderly

United States

Clinical Trials on Renal Function Impairment in Healthy Volunteers

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bulgaria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations