Clinical Trials on Renal Impaired

Total 10268 results

Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Astellas Pharma Inc

Completed

ASP8825 - Pharmacokinetics Study in Patients With Impaired Renal Function and Haemodialysis

Patients With Impaired Renal Function and Haemodialysis

Japan
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study to Evaluate the Pharmacokinetics of Apatinib in Subjects With Impaired Renal Function

Subjects With Impaired Renal Function and Healthy Subjects
University of Sao Paulo General Hospital

Completed

Effects of THW and rhTSH in Glomerular Filtration Rate During RIT

Other Impaired Renal Function Disorder

Brazil
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Renal Impairment

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetics Study of Asciminib in Subjects With Impaired Renal Function Compared to Matched Healthy Volunteers

Renal Impairment

Germany, Bulgaria
Allergan

Completed

Study of Ulipristal Acetate in Female Patients With Moderately or Severely Impaired Renal Function, Compared With Matched Healthy Female Subjects

Renal Function

United States
NicOx

Completed

A Pharmacokinetics and Safety Study of Naproxcinod in Subjects With Impaired Renal Function (HCT3012-X-106)

Renal Failure

United States
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Shire

Completed

Study of SSP-004184 (FBS0701) in Healthy Adults and Elderly Subjects and in Subjects With Impaired Renal Function

Impaired Renal Function

United States
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Renal Function

Impaired Renal Function

United States
Assistance Publique - Hôpitaux de Paris

Completed

Computer Prescribing System and Impaired Renal Function (Ordoclic-IR)

Impaired Renal Function

France
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Exelixis

Completed

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Healthy | Renal Impairment

United States
Novartis Pharmaceuticals

Completed

Multiple Dose Pharmacokinetics of LCZ696 and Its Metabolites in Subjects With Severe Renal Impairment vs. Matched Healthy Subjects With Normal Renal Function

Pharmacokinetics | Healthy Volunteer | Renal Impaired

Russian Federation, Germany, Serbia
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
Eloxx Pharmaceuticals, Inc.
Syneos Health

Completed

A Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics of ELX-02

Impaired Renal Function

United States
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics of Suvorexant in Participants With Impaired Renal Function (MK-4305-023)(COMPLETED)

Insomnia
MedDay Pharmaceuticals SA
Eurofins Optimed

Terminated

RI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Renal Impaired Patients and Healthy Subjects

Healthy Volunteers | Impaired Renal Function

France, Hungary
Gilead Sciences

Completed

Pharmacokinetics of Lanraplenib in Adults With Impaired Renal Function

Inflammatory Disease

United States, New Zealand, Germany
Merck Sharp & Dohme LLC

Completed

Efficacy, Pharmacokinetics and Safety of Org 25969 in Subjects With Normal or Impaired Renal Function (19.4.304)(P05948)(COMPLETED)

Anesthesia, General
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study of the Effect of Renal Impairment on the Pharmacokinetics of Isavuconazole.

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Renal Impaired

United States
Mast Therapeutics, Inc.

Completed

Study of the Effect of Renal Impairment on the Pharmacokinetics of Vepoloxamer

Healthy Volunteers | Renal Impaired | Pharmacokinetics of Vepoloxamer

United States
Zhejiang Medicine Co., Ltd.

Unknown

Pharmacokinetics Study of Nemonoxacin Malate Capsules in Subjects With Severe Impaired Renal Function

Kidney Dysfunction

China
GlaxoSmithKline

Completed

A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function

Solid Tumours

United States, Korea, Republic of, Netherlands
Ligand Pharmaceuticals
CyDex Pharmaceuticals, Inc.

Withdrawn

Comparison of Captisol-Enabled™ Iohexol and Omnipaque™ in Patients With Impaired Renal Function Undergoing Coronary Angiography

Contrast-induced Nephropathy
Eli Lilly and Company
CoLucid Pharmaceuticals

Completed

Study of Oral Lasmiditan in Participants With Normal and Impaired Renal Function

Migraine

Canada
Damanhour University

Completed

Linezolid Pharmacokinetics In Patients With Impaired Renal Function (PPT6) (LZDPPT6)

Renal Failure | Impaired Renal Function
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis

PK Properties Of Gabapentin In Subjects With Impaired Renal Function

Japan
Gilead Sciences

Completed

Pharmacokinetics of Bictegravir in Adults With Normal and Impaired Renal Function

HIV

United States, New Zealand
Bayer

Completed

A Study to Evaluate the Pharmacokinetics (How it Moves Into, Through and Out From the Body) of a New Gadolinium-based Contrast Agent (GBCA) After Injection and How Safe it is in Participants With Normal and Impaired Renal Function

Contrast Enhancement in Magnetic Resonance Imaging

United States
Eisai Inc.

Completed

An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Impaired Renal Function

Unspecified Adult Solid Tumor, Protocol Specific

United States
Institut Claudius Regaud

Completed

A Study Evaluating Chemotherapy With Fractionated Cisplatin/Gemcitabine Versus Carboplatin/Gemcitabine in the Treatment of Advanced or Metastatic Urothelial Cancer With Impaired Renal Function. (VEFORA)

Metastatic Urothelial Cancer | Advanced Urothelial Cancer

France
University of Cologne

Unknown

Longterm Follow-up After Remote Ischemic Preconditioning for Prevention of Contrast-induced Nephropathy (RenProLong)

Impaired Renal Function

Germany
Amgen

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function

Heart Failure

United States
Novartis Pharmaceuticals

Completed

Study of the Safety, Tolerability, and Pharmacokinetics of LHW090 in Patients With Moderately Impaired Renal Function (LHW090)

Chronic Kidney Disease (CKD)

Germany, United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Pharmacokinetics of ER OROS Paliperidone in Volunteers With Normal or Impaired Renal Function

Schizophrenia | Renal Impairment
Barts & The London NHS Trust

Withdrawn

ENvarsus for Impaired Glucose Tolerance Post REnal transplAnT (ENTREAT)

Renal Transplant Failure

United Kingdom
Karolinska Institutet
Danderyd Hospital

Completed

Platelet Function in Diabetic Patients With and Without Renal Impairment, and the Effects of Lipid Lowering Treatment (PLAUDIT)

Diabetes Mellitus | Impaired Renal Function

Sweden
University of Oslo School of Pharmacy

Completed

Efficacy and Safety of Nateglinide Treatment in Renal Transplant Recipients

Renal Transplant Recipients | Posttransplant Diabetes Mellitus | Posttransplant Impaired Glucose Tolerance

Norway
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics of Anacetrapib (MK0859) in Subjects With Impaired Renal Function (MK-0859-038)

Dyslipidemia
VA New York Harbor Healthcare System
Daxor Corporation

Completed

Blood Volume Analysis and Renal Outcomes in Hemodialysis

Kidney Failure | End Stage Renal Failure on Dialysis | Actual Impaired Fluid Volume

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Investigate the Effect of Severe Renal Impairment on Gilteritinib Compared to Healthy Participants With Normal Renal Function

Renal Impaired | Gilteritinib | Normal Renal Function | Pharmacokinetics of ASP2215

United States, Bulgaria
Atea Pharmaceuticals, Inc.

Recruiting

Study of AT-527 in Subjects With Normal and Impaired Renal Function

Renal Impairment | Healthy Volunteer

Canada
Novartis Pharmaceuticals

Terminated

A Dose-escalation Pharmacokinetic Study of Intravenous ASA404 in Adult Advanced Cancer Patients With Impaired Renal Function and Patients With Normal Renal Function

Metastatic Cancer

United States
Lebanese American University

Completed

Enoxaparin 20mg Versus 30mg Subcutaneously Once Daily in Elderly Patients With Impaired Renal Function

Renal Impairment | Venous Thromboembolism

Lebanon
Merck Sharp & Dohme LLC

Completed

A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005)

Infectious Disease
University of Regensburg

Completed

CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment (PATRON07)

End Stage Liver Disease | Impaired Renal Function

Germany

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