Clinical Trials on Renal Impairment

Total 12588 results

Pfizer

Completed

STUDY OF PF-06882961 IN PARTICIPANTS WITH TYPE 2 DIABETES MELLITUS WITH VARYING DEGREES OF RENAL IMPAIRMENT AND PARTICIPANTS WITHOUT RENAL IMPAIRMENT

Healthy | Diabetes Mellitus, Type 2 | Renal Impairment

United States
Jazz Pharmaceuticals

Completed

Assessment of the Single Dose Pharmacokinetics and Tolerability of Sativex in Patients With Impaired Hepatic Function and Healthy Patients

Hepatic Impairment

United States
Yale University

Completed

The Effects of Minocycline in Humans

Memory Impairment

United States
Seagen Inc.

Completed

A Safety Study of Tucatinib in Healthy and Hepatically-Impaired Subjects

Hepatic Impairment

United States
University of Manitoba

Unknown

Examining the Effect of a Simple Memory Tool

Memory Impairment

Canada
University of Manitoba

Unknown

Memory Intervention for Older Adults - (Social) (Social)

Memory Impairment
Genfit

Completed

Nitazoxanide Pharmacokinetic Parameters in Hepatic Impaired Patients

Liver Diseases | Moderate Hepatic Impairment | Severe Hepatic Impairment

United States
Rush University Medical Center

Recruiting

Outcome Comparisons of Vibratory Airway Clearance Devices

Airway Clearance Impairment

United States
Stony Brook University

Unknown

Evaluating the Telehealth Single Session Consultation Service

Mental Health Impairment

United States
VA Office of Research and Development
VHA Geriatrics and Extended Care; US Department of Health and Human Services... and other collaborators

Completed

Evaluation of Veteran-Directed Home and Community Based Services (VD-HCBS Eval)

Caregiving | Functional Impairment

United States
University of Bergen
Haukeland University Hospital; Wisconsin Department of Health and Family Services and other collaborators

Completed

Key Nutrients and Mental Health

Mental Health Impairment

United States
Claudia Aristizábal
Sanitas University

Not yet recruiting

Music Therapy Songwriting and Mental Health in Neonatel Intensive Care Unit (NICU) Parents

Mental Health Impairment

Colombia, Poland
University of Texas Southwestern Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Attenuation of Corticosteroid Induced Hippocampal Changes

Organic Memory Impairment

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men

Severe Hepatic Impairment | Normal Hepatic Function

Bulgaria
GE Healthcare

Withdrawn

Renal Effects of Three Iodinated Contrast Media (CM) in Patients at Risk Undergoing Coronary Angiography

Diabetes Mellitus | Renal Impairment | Coronary Artery Disease (CAD)

United States, Germany
Sanofi

Terminated

Gla-300 and IDeg-100 in Insulin-Naïve People With Type 2 Diabetes Mellitus and Renal Impairment (TRENT)

Type 2 Diabetes Mellitus | Renal Impairment

United States, Czechia, Hungary, Poland, Serbia
Hellenic Society of Hematology
Sanofi

Not yet recruiting

A Phase 2 Study of Isatuximab in Combination With Pomalidomide and Dexamethasone in MM Patients Who Received One Prior Line of Therapy Containing Lenalidomide and a Proteasome Inhibitor

Neoplasms | Neoplasms by Histologic Type | Hematologic Diseases | Multiple Myeloma | Neoplasms, Plasma Cell | Paraproteinemias | Blood Protein Disorders | Renal Impairment

Greece
Hellenic Society of Hematology
Sanofi

Not yet recruiting

A Phase 2 Study of Isatuximab in Combination With Bortezomib, Cyclophosphamide and Dexamethasone Followed by Isatuximab and Lenalidomide Maintenance in Newly Diagnosed Patients With Multiple Myeloma and Severe Renal Impairment

Neoplasms | Neoplasms by Histologic Type | Hematologic Diseases | Multiple Myeloma | Neoplasms, Plasma Cell | Paraproteinemias | Blood Protein Disorders | Renal Impairment

Greece
Pfizer

Terminated

A Clinical Trial of the Study Medicine (PF-07081532) in People With Diabetes and Kidney Dysfunction

Renal Impairment | Type 2 Diabetes

United States
Hoffmann-La Roche

Completed

A Study of Peginterferon Alfa-2a (Pegasys) and Ribavirin (Copegus) Combination Therapy in Participants With Chronic Hepatitis C (CHC) and Various Degrees of Renal Impairment

Hepatitis C, Chronic

Sweden, New Zealand, United States, France, Brazil
Taisho Pharmaceutical Co., Ltd.

Completed

A Pharmacokinetic Study of TS-142 in Patients With Hepatic Impairment

Patients With Mild or Moderate Hepatic Impairment

Japan
Shanghai 10th People's Hospital

Not yet recruiting

Effects of Intrapulmonary Percussive Ventilator on Respiratory Function

Airway Clearance Impairment

China
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effects of Selpercatinib in Hepatically Impaired Participants and Healthy Participants

Healthy | Hepatic Impairment

United States
University of Roehampton
MIND Tower Hamlets

Terminated

Effectiveness of Tracking Goals in Counselling (Goals in MIND)

Mental Health Impairment

United Kingdom
Stony Brook University

Completed

Evaluating the Single-Session Consultation Service at the Krasner Psychological Center and Putnam (SSC@KPC&Putnam)

Mental Health Impairment

United States
McMaster University
Hamilton Health Sciences Corporation; Ontario Mental Health Foundation; St. Joseph...

Completed

Impact Study of Workplace Mental Health Education on Early Intervention for Healthcare Workers With Mental Health Issues

Mental Health Impairment

Canada
AstraZeneca

Completed

The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers

Healthy | Memory Impairment

United States
Linkoeping University

Completed

Digital Support for People With Cognitive Impairment

Stroke | Brain Injuries | Cognitive Impairments

Sweden
Daiichi Sankyo, Inc.

Completed

Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants

Moderate Hepatic Impairment

United States
Astellas Pharma Europe B.V.

Completed

A Study to Investigate the Effect of Mirabegron (YM178) on Subjects With Mild or Moderate Hepatic Impairment Compared to Healthy Subjects

Healthy Subjects | Pharmacokinetics | Mild and Moderate Hepatic Impairment

Slovakia
University of California, San Francisco
National Institute on Aging (NIA)

Active, not recruiting

Brain Health Together: A Live-Streaming Group-Based Digital Program

Mild Cognitive Impairment | Cognitive Decline | Cognitive Deterioration | Cognitive Impairment, Mild | Cognitive Deficits, Mild

United States
University of California, Irvine
National Institute on Aging (NIA)

Recruiting

Using Nicotine to Reverse Age-related Auditory Processing Deficits (Nicotine)

Aging | Auditory Perceptual Impairment

United States
University of Colorado, Denver

Completed

Identifying and Treating Physical Function Impairment in Elders

Physical Activity | Physical Impairment

United States
Université du Québec a Montréal

Completed

Protein Supplementation and Mixed Power Training on Muscle Function and Functional Capacities in Elderly Men (PROMU)

Aging | Dynapenia | Physical Impairment
University of Hawaii

Recruiting

Natives Engaged in Alzheimers Research - 'Ike Kupuna (NEAR)

Mild Cognitive Impairment | Subjective Cognitive Impairment

United States
Atea Pharmaceuticals, Inc.

Recruiting

Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment | Healthy Volunteer

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

An Investigational Study of SHR3680 in Participants With Mild to Moderate Liver Impairment and Healthy Participants

Hepatic Impairment | Healthy Participants

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Liver Function

Healthy Subjects | Hepatic Impairment

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

An Investigational Study of SHR6390 in Participants With Mild to Moderate Liver Impairment and Healthy Participants

Hepatic Impairment | Healthy Participants
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug Levels, Safety, and Tolerability of BMS-986036 in Participants With Normal Liver Function and Participants With Moderate and Severe Liver Impairment

Moderate Liver Impairment | Severe Liver Impairment

United States
Merck Sharp & Dohme LLC

Completed

A Study to Assess Pharmacokinetics of Preladenant in Participants With Chronic Hepatic Impairment (P06513)

Chronic Hepatic Impairment
VA Office of Research and Development

Active, not recruiting

Optimizing Function and Independence Through iHI-FIVES

Cognitive Impairment | Functional Impairment

United States
Sunnybrook Health Sciences Centre

Recruiting

Exercise as a Primer for Brain Stimulation in Vascular Cognitive Impairment No Dementia (VCIND) (EXPRESS-V)

Mild Cognitive Impairment | Vascular Cognitive Impairment

Canada
Baycrest
Centre for Aging and Brain Health Innovation

Unknown

Online Cognitive Rehabilitation of Executive Dysfunction in Nonamnestic MCI

Neurocognitive Disorders | Cognitive Dysfunction | Mental Disorder | Cognitive Impairment, Mild | Cognitive Disorder | Nonamnestic Mild Cognitive Impairment

Canada
University of Zurich

Recruiting

Longitudinal Investigation of Brain Blood Flow Changes in Neurosurgical Patients

Brain Blood Flow Impairment

Switzerland
University of Massachusetts, Worcester
Binghamton University; National Institute on Disability, Independent Living... and other collaborators

Active, not recruiting

Helping Youth on the Path to Employment (HYPE)

Educational Problems | Mental Impairment

United States
Shirley Ryan AbilityLab

Terminated

TMS for Investigating Memory Facilitation

Age-associated Memory Impairment

United States
University of Medicine and Dentistry of New Jersey
Foundation for Anesthesia Education and Research; New Jersey Eye Institute

Terminated

Intraocular Pressure During Prone Spinal Surgery

Spine Surgery | Vision Impairment

United States
Vanderbilt University

Completed

COgnitive and Physical Exercise (COPE) Prehabilitation Pilot Feasibility Study

Postoperative Complications | Cognitive Impairment | Physical Impairment

United States

Clinical Trials on Renal Impairment

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