Clinical Trials on Resectable Digestive System Carcinoma

Total 48300 results

P.O. Witteveen
Merck KGaA, Darmstadt, Germany

Terminated

Study of Combination of Cetuximab and Radiotherapy Added to the Standard Treatment for Oesophageal Adenocarcinoma (TRACC)

Resectable Esophageal Cancer

Netherlands
MedImmune LLC

Completed

MEDI-573 in Combination With SOC in Unresectable or Metastatic HCC. (MEDI-573-1028)

Unresectable or Metastatic Hepatocellular Carcinoma (HCC)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study

Borderline Resectable Pancreatic Adenocarcinoma | Resectable Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma

United States
Gruppo Oncologico del Nord-Ovest

Recruiting

Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)

Colorectal Cancer | Resectable Colorectal Carcinoma

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant

Cholangiocarcinoma | Adult Hepatocellular Carcinoma | Resectable Hepatocellular Carcinoma | Benign Liver Tumor | Metastases to Liver

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
National Cancer Center, Korea

Completed

Induction Chemotherapy With Gemcitabine and Cisplatin Followed by CCRT for Unresectable Pancreatic Carcinoma

Pancreatic Carcinoma Non-resectable

Korea, Republic of
Guohui Xu

Recruiting

TACE Plus Camrelizumab and Apatinib for Unresectable Hepatocellular Carcinoma

Unresectable Hepatocellular Carcinoma | Apatinib | Camrelizumab | Transarterial Chemoembolization

China
University of British Columbia

Completed

TACE Study-Liver Embolization Perfusion (VGH Radiology LIU) (TACE)

Unresectable Hepatocellular Carcinoma | Undergoing Chemoembolization and Radioembolization

Canada
Xinrui Zhu

Enrolling by invitation

The Safety and Efficacy of Transarterial Chemoembolization (TACE) + Lenvatinib + Programmed Cell Death Protein 1 (PD-1) Antibody of Advanced Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma Non-resectable | Tyrosine Kinase Inhibitor | Transarterial Chemoembolization | Immune Checkpoint Blockade

China
Center Eugene Marquis

Suspended

Selective Internal Radiation Therapy and Capecitabine (Chemotherapy) Treatment for Liver Cancer (SIROCHO)

Resectable Intrahepatic Cholangiocarcinoma

France
National Cancer Institute (NCI)

Recruiting

Durvalumab With Gemcitabine and Cisplatin for the Treatment of High-Risk Resectable Liver Cancer Before Surgery

Resectable Intrahepatic Cholangiocarcinoma

United States
Kimberly Perez, MD
Novartis

Terminated

A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer

Pancreatic Cancer | Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer | Borderline Resectable Pancreatic Adenocarcinoma

United States
M.D. Anderson Cancer Center

Recruiting

Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer

Stage IB Hepatocellular Carcinoma AJCC v8 | Stage II Hepatocellular Carcinoma AJCC v8 | Resectable Hepatocellular Carcinoma | Stage I Hepatocellular Carcinoma AJCC v8 | Stage IA Hepatocellular Carcinoma AJCC v8

United States
Tang-Du Hospital

Enrolling by invitation

Prospective Cohort Study of Neoadjuvant Therapy With Sintilimab (PD-1 Inhibitor) Combined With Chemotherapy in Resectable ESCC

Resectable Esophageal Squamous Cell Carcinoma

China
BeiGene

Active, not recruiting

Study of Tislelizumab in Participants With Resectable Esophageal Squamous Cell Carcinoma

Resectable Esophageal Squamous Cell Carcinoma

China
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

Pancreatic Adenocarcinoma | Resectable Pancreatic Carcinoma

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Yttrium Y 90 Resin Microspheres Data Collection in Unresectable Liver Cancer: the RESIN Study (RESiN)

Localized Non-Resectable Adult Liver Carcinoma

United States
Kindai University

Unknown

Transcatheter Arterial Chemoembolization Therapy In Combination With Sorafenib (TACTICS)

Carcinoma, Hepatocellular | Hepatocellular Carcinoma | Liver Neoplasm | Unresectable Hepatocellular Carcinoma

Japan
Mayo Clinic

Completed

Intravital Microscopy in Human Solid Tumors

Malignant Solid Neoplasm | Gastric Carcinoma | Solid Tumor, Adult | Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Metastatic Gastric Carcinoma | Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8 | Metastatic Sarcoma | Resectable... and other conditions

United States
Peking Union Medical College Hospital

Recruiting

The Value of Molecular Residual Disease Monitoring Based on ctDNA in Resected Pancreatic Cancer (MAP-02)

Pancreatic Cancer | Resectable Carcinoma

China
Abramson Cancer Center of the University of Pennsylvania

Completed

Sorafenib Tosylate and Chemoembolization in Treating Patients With Unresectable Liver Cancer

Hepatocellular Carcinoma | Liver Cancer | Localized Unresectable Liver Cancer

United States
Centre Francois Baclesse
National Cancer Institute, France

Active, not recruiting

Perioperative Treatment in Resectable Gastric Cancer With Spartalizumab (PDR001) in Combination With Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel (FLOT) (GASPAR)

Resectable Carcinoma | Gastric Cancer by AJCC V8 Stage

France
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Enrolling by invitation

Gene Expression Profile of Resected Pancreatic and Ampullary Adenocarcinoma at Favorable Prognosis

Resectable Pancreatic Adenocarcinoma

Italy
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Unresectable Intrahepatic Cholangiocarcinoma

United States
Xuzhou Medical University
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical...

Unknown

Early Oral Intake After Pancreaticoduodenectomy in the Age of ERAS

Pancreaticoduodenectomy | Periampullary Carcinoma Resectable

China
First Affiliated Hospital of Zhejiang University

Recruiting

A Phase II Prospective Trial of mXELOXIRI Reintroduction for mCRC

Unresectable Metastatic Colorectal Carcinoma

China
Mayo Clinic

Recruiting

68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer

Advanced Hepatocellular Carcinoma | Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8

United States
Sirtex Medical
Bright Research Partners

Recruiting

Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients (DOORwaY90)

Unresectable Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | BCLC Stage A Hepatocellular Carcinoma

United States
Zhejiang Cancer Hospital

Unknown

Study of Nimotuzumab in Combination With Neoadjuvant Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma Resectable

China
Massachusetts General Hospital

Terminated

Phase II Study of Preoperative FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel in Patients With Resectable Pancreatic Cancer

Resectable Pancreatic Cancer | Pancreatic Ductal Carcinoma

United States
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

A Phase Ⅱ Clinical Trial of Camrelizumab for Adjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma

Resectable Esophageal Squamous Cell Carcinoma
Centre Leon Berard

Not yet recruiting

Evaluation of the High Intensity Focused Ultrasound (HIFU) Technique for Patients With Unresectable Pancreatic Tumor Treatment (PULS) (PULS)

Non-Resectable Pancreas Carcinoma

France
NewLink Genetics Corporation

Terminated

Immunotherapy and SBRT Study in Borderline Resectable Pancreatic Cancer

Pancreatic Cancer | Pancreatic Carcinoma Non-resectable

United States
Nerviano Medical Sciences

Active, not recruiting

Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy

Unresectable Hepatocellular Carcinoma (HCC)

Italy, Spain, United States
Zhigang Li
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial Of Neoadjuvant Chemotherapy or Radiochemotherapy With Or Without SHR-1210 In Patients With Resectable ESCC.

Locally Advanced Resectable Esophageal Squamous Cell Carcinoma

China
Abramson Cancer Center at Penn Medicine

Recruiting

A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer

Locally Advanced Unresectable Pancreatic Cancer Treated With Chemoradiotherapy | Borderline Resectable Pancreatic Cancer Treated With Chemoradiotherapy

United States
National Cancer Institute (NCI)

Terminated

Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Metastatic Pancreatic Cancer | Histologically or Cytologically Confirmed Pancreatic Cancer | Unresectable or Borderline Resectable Pancreatic Cancer

United States
Yonsei University

Recruiting

A Phase 2 Trial of Neoadjuvant Modified FOLFIRINOX Chemotherapy for Resectable Pancreatic Adenocarcinoma

Resectable Pancreatic Adenocarcinoma

Korea, Republic of
Jean-Luc Van Laethem
Roche Pharma AG

Unknown

Effect on Tumor Perfusion of a Chemotherapy Combining Gemcitabine and Vismodegib Before Surgery in Pancreatic Cancer (NEOPACHI-001)

Pancreatic Adenocarcinoma Resectable

Belgium
AIO-Studien-gGmbH
AstraZeneca

Completed

Durvalumab and Tremelimumab With Gemcitabine or Gemcitabine/Cisplatin Compared to Gemcitabine/Cisplatin in CCA Patients (IMMUCHEC)

Cholangiocarcinoma | Cholangiocarcinoma Non-resectable | Gall Bladder Carcinoma | Gallbladder Carcinoma Non-Resectable

Germany
Guangzhou Institute of Respiratory Disease

Not yet recruiting

Cadonilimab in Combination With Chemotherapy for Locally Advaced Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Resectable Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

Esophageal Arterial Infusion Chemotherapy Versus Systemic Intravenous Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Prospective, Multicentre, Randomised Controlled Clinical Study

Resectable Locally Advanced Esophageal Squamous Cell Carcinoma
University of Salzburg
Biolitec Pharma Ltd.

Unknown

Single-arm Study of Photodynamic Laser Therapy Using Foscan for Non-curatively-resectable Bile Duct Carcinoma

Non-curative Resectable Bile Duct Carcinoma

Austria, Germany
Georgetown University
AstraZeneca

Recruiting

Neoadjuvant Tremelimumab and Durvalumab With Gem/Cis in Intrahepatic Cholangiocarcinoma (ESR-22-21719)

Biliary Tract Cancer | Borderline Resectable Carcinoma

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Noordwest Ziekenhuisgroep

Active, not recruiting

Blood-borne Assessment of Stromal Activation in Esophageal Adenocarcinoma to Guide Tocilizumab Therapy (BASALT)

Oesophageal Adenocarcinoma | Esophageal Adenocarcinoma | Resectable Carcinoma

Netherlands
National Cancer Institute (NCI)

Terminated

BMS-247550 in Treating Patients With Liver or Gallbladder Cancer

Advanced Adult Primary Liver Cancer | Localized Extrahepatic Bile Duct Cancer | Localized Gallbladder Cancer | Localized Resectable Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent... and other conditions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer

Pancreatic Cancer | Pancreatic Adenosquamous Carcinoma | Resectable Pancreatic Adenocarcinoma

United States, Canada
Edward Nelson

Completed

Administration as a Biological Adjuvant in Clinically-Staged, Resectable Pancreatic Adenocarcinoma

Pancreatic Cancer | Resectable Pancreatic Adenocarcinoma

United States
Scripps Health

Terminated

PEGPH20 Plus Gemcitabine With Radiotherapy in Patients With Localized, Unresectable Pancreatic Cancer (HALO-IST)

Pancreatic Adenocarcinoma Non-resectable

United States

Clinical Trials on Resectable Digestive System Carcinoma

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