Clinical Trials on Respiratory Depression in Japan

Total 1194 results

Takeda

Completed

Phase III Study of Intramuscular TAK-816 in Healthy Infants

Healthy Volunteers | Haemophilus Influenzae Type b, Prevention

Japan
Merck Sharp & Dohme LLC

Completed

Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension Study

Non-Small-Cell Lung Carcinoma

Japan
Eli Lilly and Company
Alkermes, Inc.

Completed

A Study for Patients With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

Japan, Taiwan
Tjip van der Werf
Gadjah Mada University; The Enose Company, Zutphen the Netherlands

Completed

ENOSE in Pulmonary Tuberculosis in Yogyakarta (YOGYATBNOSE)

Pulmonary Tuberculosis Suspected | Other Specified Chronic Obstructive Pulmonary Disease | Pulmonary Tuberculosis TB (+) Histology, (-) Bacteriology

Indonesia
Boehringer Ingelheim

Completed

Safety and PK Study of BIBF 1120 in Japanese Patients With IPF

Idiopathic Pulmonary Fibrosis

Japan
Pulmonx Corporation

Recruiting

Zephyr Valve Japan Post-Marketing Surveillance

Emphysema | COPD | Severe Emphysema

Japan
Olympus Corporation

Terminated

A Prospective Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the OL-BF-001 for Severe Emphysema

Emphysema

Japan
Wafaa Mahmoud Amin
Cairo University

Completed

The Effect of BMI on Hand Grip Force in Healthy Adults

Overweight and Obesity | Motor Activity | Hand Injuries

Saudi Arabia
Merck Sharp & Dohme LLC

Completed

Study of Gefapixant (MK-7264) in Adult Japanese Participants With Unexplained or Refractory Chronic Cough (MK-7264-033)

Chronic Cough

Japan
Osaka General Medical Center
Wakayama Medical University; Nagasaki University; University of the Ryukyus; Kansai... and other collaborators

Completed

GRam Stain-guided Antibiotics ChoicE for Ventilator-Associated Pneumonia (GRACE-VAP) Trial

Ventilator Associated Pneumonia

Japan
University of Toyama

Unknown

Feasibility Study of CDDP + CPT-11 + PSK for Extensive-Stage Disease (ED) Small Cell Lung Cancer (RNCLC)

Small Cell Lung Cancer

Japan
St. Justine's Hospital
University of Maryland, College Park; Tokyo Women's Medical University; Tokyo... and other collaborators

Enrolling by invitation

The Medical Management in Patients Exposed to Weapons of Mass Destruction (CBRNEObs)

Acute Respiratory Distress Syndrome | Medical Emergencies | Distress Respiratory Syndrome | Chemical Injury | Chemicals; Intoxication

Canada, France, Japan, United States
AstraZeneca

Completed

Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors

Stomach Neoplasms | Small Cell Lung Carcinoma | Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms | Triple Negative Breast Neoplasms | Esophageal Squamous Cell Carcinoma | Carcinoma, Pancreatic Ductal | Carcinoma, Squamous Cell of Head and Neck | Esophagogastric Junction Neoplasms

Korea, Republic of, Japan
Novartis Pharmaceuticals

Completed

Special Drug Use Observational Study of Xolair in Patients With Severe to Most Severe Seasonal Allergic Rhinitis Aged ≥ 12 Years and < 18 Years Whose Symptoms Were Inadequately Controlled Despite to Conventional Therapies

Allergic Rhinitis

Japan
AstraZeneca

Completed

Asia PDL1 Study Among NSCLC Patients (MEDI-APEX)

Locally Advanced or Metastatic NSCLC

Korea, Republic of, China, Japan
University Hospital, Caen

Unknown

Ventilation in Cardiac Surgery (VENICE)

Anesthesia, General | Respiration, Artificial | Respiratory Complication | Bypass, Cardiopulmonary

Poland, Norway, France, Belgium, Brazil, Czechia, Germany, Italy, Japan, Netherlands
Neonatal Encephalopathy Consortium, Japan
National Cerebral and Cardiovascular Center; Nagoya University; Tokyo Women's... and other collaborators

Completed

Autologous Cord Blood Cell Therapy for Neonatal Encephalopathy

Neonatal Encephalopathy | Hypoxic-ischemic Encephalopathy

Japan
Neonatal Encephalopathy Consortium, Japan
National Cerebral and Cardiovascular Center; Nagoya University; Tokyo Women's... and other collaborators

Unknown

Cytokines Associated With Cord Blood Cell Therapy for Neonatal Encephalopathy

Neonatal Encephalopathy (Neonatal Hypoxic-ischemic Encephalopathy)

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Dose-ranging Trial of OPC-249 Powder Inhalation in Patients With Pain Due to Osteoporosis

Pain Due to Osteoporosis

Japan
Mie University

Completed

Radiofrequency Ablation in Resectable Colorectal Lung Metastasis

Colorectal Cancer | Lung Metastasis

Japan
Sanofi Pasteur, a Sanofi Company

Completed

DTaP-IPV/Hib Vaccine Primary & Booster Vaccinations Versus Co-administration of DTaP-IPV and Hib Vaccine in Japanese Infants

Pertussis | Tetanus | Diphtheria | Bacterial Meningitis | Poliomyelitis

Japan
GlaxoSmithKline

Completed

Efficacy and Safety of Fluticasone Propionate(FP)/ Salmeterol Xinafoate (SLM) Hydro Fluoro Alkane (HFA) Metered Dose Inhaler (MDI) in Pediatric Patients With Bronchial Asthma

Asthma

Japan
Mylan Inc.

Completed

Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Digestive System Diseases | Pancreatic Diseases | Cystic Fibrosis | Exocrine Pancreatic Insufficiency

Japan
AstraZeneca

Completed

IMFINZI Study in Patients With Extensive Stage Small Cell Lung Cancer

Carcinoma, Small Cell

Japan
Dr. Christoph Schukro
Boston Scientific Corporation

Unknown

Validation of the "ApneaScan" Algorithm for the Detection of Sleep Disordered Breathing in Chronic Heart Failure (VASA)

Chronic Heart Failure | Sleep-disordered Breathing

Austria, Germany, Japan, Switzerland
GlaxoSmithKline

Completed

The Treatment of Acute Pulmonary Thromboembolism (PE) of GSK576428 (Fondaparinux Sodium) in Japanese Patients

Embolism, Pulmonary

Japan
Deep Breeze

Completed

Vibration Response Imaging (VRI) in Patients That Are Undergoing Pulmonary Interventional Procedure

Central Airway Stenosis

United States, France, Germany, Japan
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Pharmacodynamics, Efficacy and Safety of Omalizumab in Japanese Children (6 - 15 Years)

Allergic Asthma

Japan
GlaxoSmithKline

Completed

Pharmacokinetics and Pharmacodynamics of Mepolizumab Administered Subcutaneously in Children

Asthma

Japan, United States, United Kingdom, Poland
GlaxoSmithKline

Completed

A Long-term Safety Study of Fluticasone Furoate (FF)/GW642444 in Japanese Subjects With COPD

Pulmonary Disease, Chronic Obstructive

Japan
Novartis Pharmaceuticals

Completed

Long-term Safety, Tolerability and Efficacy of Omalizumab in Japanese Children

Allergic Asthma

Japan
Bayer

Completed

A Phase III Study to Evaluate the Safety, Efficacy and Pharmacokinetics/Pharmacodynamics of BAYQ3939 in Patients With Bacterial Pneumonia

Pneumonia

Japan
Ablynx

Terminated

Evaluation of ALX-0171 in Japanese Children Hospitalized for Respiratory Syncytial Virus Lower Respiratory Tract Infection

Respiratory Syncytial Virus Lower Respiratory Tract Infection

Japan
Boehringer Ingelheim

Recruiting

A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

Patients With Small Cell Lung Carcinoma and Other Neoplasms

United States, Spain, Germany, Japan
Eli Lilly and Company

Completed

A Study of Necitumumab in the First-Line Treatment of Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC)

Squamous Non-small Cell Lung Cancer

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Open Label Study of Sildenafil in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

Japan
AbbVie

Recruiting

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (LIVIGNO-4)

Non-Small Cell Lung Cancer

United States, Israel, Japan
National Hospital Organization Kinki-chuo Chest...

Unknown

Quality of Life in Patients Who Are Receiving Either Vinorelbine, Gemcitabine, and Docetaxel or Paclitaxel and Carboplatin for Advanced Non-Small Cell Lung Cancer

Lung Cancer

Japan
AstraZeneca

Active, not recruiting

FASENRA SCEI for Long-term Use

Asthma

Japan
Janssen Pharmaceutical K.K.

Recruiting

A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Japan
Eli Lilly and Company
ICOS Corporation

Completed

Study the Safety and Effectiveness of Tadalafil on High Blood Pressure in the Blood Vessel Going From the Heart to the Lungs

Hypertension, Pulmonary

United States, Belgium, Canada, France, Germany, Ireland, Italy, Japan, Spain, United Kingdom
Novartis Pharmaceuticals

Terminated

Study of CLR457 Administered Orally in Adult Patients With Advanced Solid Malignancies

Advanced Solid Tumor

Spain, Singapore, Japan, United States, Canada
Novartis Pharmaceuticals

Completed

LDK378 in Patients With ALK Positive NSCLC Previously Treated With Alectinib.

Non-Small-Cell Lung Cancer

Japan
AstraZeneca

Completed

Safety & Efficacy of Symbicort® Turbuhaler® (1, 2, and 4 x 160/4.5 µg Twice Daily) in Japanese Patients With Asthma

Asthma

Japan
Mitsubishi Tanabe Pharma Corporation
The Research Foundation for Microbial Diseases of Osaka University

Completed

Study of BK1301 (DTaP Vaccine) as a Booster in Adolescents

Pertussis | Tetanus | Diphtheria

Japan
Japan Multinational Trial Organization

Completed

Vinorelbine, Gemcitabine, and Docetaxel Compared With Paclitaxel and Carboplatin in Treating Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

Japan
Taiho Pharmaceutical Co., Ltd.

Recruiting

AB122 Platform Study

Gastric Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Alveolar Soft Part Sarcoma | Advanced or Metastatic Solid Tumor

Japan
AstraZeneca

Completed

A Study to Compare Severe Asthma Patients Who Start Biologics and Who do Not Start (PROSPECT)

Asthma

Japan
AstraZeneca

Recruiting

Evusheld Japan PMS_Japan Post-Marketing Surveillance (PMS)

SARS-CoV-2 Infection

Japan
Novartis Pharmaceuticals

Completed

A Long-term Safety Study of QMF149 in Japanese Participants With Asthma

Asthma

Japan

Clinical Trials on Respiratory Depression in Japan

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