Clinical Trials on SLL

Total 435760 results

University of Alberta

Withdrawn

Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache

Hemorrhagic Stroke | Reversible Cerebral Vasoconstriction Syndrome | Cerebral Venous Sinus Thrombosis | Headache, Migraine | Stroke (CVA) or TIA | Botulinum Toxins, Type A | Carotid Dissection Artery | Vertebral Dissection Artery

Canada
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Eli Lilly and Company; James and Esther King Biomedical...

Active, not recruiting

Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma | Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Cancer | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx | Squamous Cell Carcinoma of the Paranasal...

United States
Duke University

Completed

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

Head Injuries, Closed | Head Trauma | Head Injuries | Craniocerebral Injuries | Crushing Skull Injury | Head Injuries, Multiple | Head Trauma,Closed | Head Trauma Injury | Head Trauma, Penetrating | Head Injury, Minor | Head Injury Major | Head Injury, Open | Injuries, Craniocerebral | Injuries, Head | Multiple Head... and other conditions

United States, Uganda
Reata, a wholly owned subsidiary of Biogen

Terminated

An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE) (EAGLE)

Chronic Kidney Diseases | Autosomal Dominant Polycystic Kidney | Alport Syndrome

United States, France, Australia, Japan, Spain, Puerto Rico
Sidney Kimmel Cancer Center at Thomas Jefferson...
Pfizer

Active, not recruiting

Sunitinib Malate or Valproic Acid in Preventing Metastasis in Patients With High-Risk Uveal Melanoma

Ciliary Body and Choroid Melanoma, Medium/Large Size | Ciliary Body and Choroid Melanoma, Small Size | Iris Melanoma | Stage IIIA Intraocular Melanoma | Stage IIIB Intraocular Melanoma | Stage IIIC Intraocular Melanoma | Stage I Intraocular Melanoma | Stage IIA Intraocular Melanoma | Stage IIB Intraocular... and other conditions

United States
AO GENERIUM

Active, not recruiting

A Phase 1 Study of GNR-051 in Subjects With Advanced Malignancies

Melanoma | Carcinoma, Renal Cell | Carcinoma, Non-Small-Cell Lung

Russian Federation
Lawson Health Research Institute

Active, not recruiting

Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus.

Carcinosarcoma | Endometrioid Adenocarcinoma | Clear Cell Carcinoma | Serous Carcinoma | Dedifferentiated Carcinoma

Canada
University Hospital, Gentofte, Copenhagen

Active, not recruiting

The Relationship Between Inflammatory ARTritis and CArdiac DIseAse (ARTCADIA)

Myocardial Infarction | Heart Failure | Stroke | Rheumatoid Arthritis | Ischemic Heart Disease | Inflammatory Arthritis | Heart Failure, Diastolic | Valvular Heart Disease | Heart Failure, Systolic | Spondylitis, Ankylosing | Cardiac Disease | Spondyloarthritis | Axial Spondyloarthritis | Myocardial Dysfunction | Left...

Denmark
Chulalongkorn University

Completed

Vitamin D Levels in Non-immediate Drug Hypersensitivity Case-control Study

Vitamin D Deficiency | Stevens-Johnson Syndrome | Maculopapular Exanthem | Drug Reaction With Eosinophilia and Systemic Symptom | Drug-Induced Rash

Thailand
Mayo Clinic
National Cancer Institute (NCI)

Completed

Study of Mucosal Sparing Adjuvant Radiotherapy After Surgical Exploration in HPV+ Head and Neck Cancer of Unknown Primaries

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive)... and other conditions

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer

Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | EGFR Gene Mutation | Unresectable Lung Non-Small... and other conditions

United States
Julie L. Sutcliffe, Ph.D
National Cancer Institute (NCI)

Active, not recruiting

First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide

Breast Carcinoma | Lung Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Metastatic Malignant Neoplasm in the Lung | Metastatic Malignant Neoplasm in the Breast | Metastatic Malignant Neoplasm in the Colon | Metastatic Malignant Neoplasm in the Rectum

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Acupuncture for the Treatment of Intravesical BCG-Related Adverse Events in High-Risk Non-muscle Invasive Bladder Cancer

Recurrent Bladder Urothelial Carcinoma | Bladder Urothelial Carcinoma In Situ | Stage 0a Bladder Cancer AJCC v8 | Stage 0is Bladder Cancer AJCC v8 | Stage I Bladder Cancer AJCC v8 | Superficial Bladder Urothelial Carcinoma

United States
Mandos LLC

Terminated

Open-label Study of VTS-270 in Participants With Neurologic Manifestations of Niemann-Pick Type C1

Niemann-Pick Disease, Type C

Costa Rica
National Cancer Institute (NCI)

Completed

Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

Neurofibromatosis Type 1 | Cutaneous Neurofibroma | Optic Nerve Glioma

United States
US Biotest, Inc.

Terminated

Safety and Efficacy of USB002 for Respiratory Distress Due to COVID-19

SARS-CoV-2 Infection | Respiratory Distress Syndrome, Adult | Adult Respiratory Distress Syndrome | COVID-19 Virus Infection | SARS Coronavirus 2 Infection | 2019 Novel Coronavirus Infection

United States
Beth Israel Deaconess Medical Center
Genzyme, a Sanofi Company

Completed

Reduced Intensity Conditioning With Clofarabine, Antithymocyte Globulin (ATG), Total Lymphoid Irradiation (TLI) Followed by Allogeneic Stem Cell Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Hodgkins Disease | Relapsed/Refractory Chronic Lymphocytic Leukemia | Relapsed Refractory Multiple Myeloma | Relapsed/Refractory Non Hodgkin's Lymphoma

United States
HUYABIO International, LLC.

Completed

Study of HBI-8000 With Nivolumab in Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung Cancer

Melanoma | Renal Cell Carcinoma | Non-Small Cell Lung Cancer

United States
Teal Health, Inc.

Active, not recruiting

Development of a Self-collection Device for Cervical Cancer Screening

Human Papilloma Virus | Human Papilloma Virus Infection Type 16 | Human Papilloma Virus Infection Type 18

United States
University of Washington
National Cancer Institute (NCI)

Terminated

Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer

Metastatic Prostate Carcinoma | Prostate Adenocarcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Prostate Small Cell Neuroendocrine Carcinoma | Castration-Sensitive Prostate Carcinoma

United States
Mercy Medical Center

Active, not recruiting

HOT: HIPEC in Ovarian Cancer as Initial Treatment (CRS/HIPEC)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Fallopian Tube Carcinoma | Ovarian Carcinoma | Primary Peritoneal Carcinoma | Stage IV Ovarian Cancer | Stage III Ovarian Cancer

United States
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH); RefleXion...

Completed

Fludeoxyglucose F-18-PET in Planning Lung Cancer Radiation Therapy

Stage IB Non-Small Cell Lung Carcinoma AJCC v7 | Stage II Non-Small Cell Lung Cancer AJCC v7 | Stage IIA Non-Small Cell Lung Carcinoma AJCC v7 | Stage IIB Non-Small Cell Lung Carcinoma AJCC v7 | Stage I Lung Cancer | Stage II Lung Cancer | Stage I Non-Small Cell Lung Cancer AJCC v7 | Stage IA Non-Small...

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Maryland Cigarette Restitution Fund

Completed

Behavioral Weight Loss Program for Cancer Survivors in Maryland (ASPIRE)

Kidney Cancer | Breast Cancer | Rectal Cancer | Prostate Cancer | Bladder Cancer | Endometrial Cancer | Melanoma (Skin) | Gallbladder Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Autologous T Cells With or Without Cyclophosphamide and Fludarabine in Treating Patients With Recurrent or Persistent Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer (Fludarabine Treatment Closed as of 12/01/2009)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

United States
Center for International Blood and Marrow Transplant...
Sanofi; Genzyme, a Sanofi Company

Completed

A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor

Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Hodgkin's Disease | Related Donors Donating Peripheral Blood Stem Cells (PBSC) to a Family Member

United States
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

An Investigational Scan (7 Tesla MRI) in Diagnosing Cognitive Impairment in Patients With Non-Metastatic Prostate Cancer

Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IIA Prostate Cancer AJCC v8 | Stage IIB Prostate... and other conditions

United States
Alexandria University
Science and Technology Development Fund (STDF), ,Egypt

Completed

Safety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University Hospital

Pulmonary Fibrosis | Cytokine Release Syndrome | COVID-19 Acute Respiratory Distress Syndrome

Egypt
Hamad Medical Corporation

Completed

COVID-19 Among Children With Chronic Renal Diseases in Qatar (CCCRDQ)

Chronic Kidney Diseases | Acute Kidney Injury | COVID-19 Pandemic | COVID-19 Infection | Chronic Renal Failure in Children

Qatar
Blueprint Medicines Corporation

Terminated

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

Neoplasms | Respiratory Tract Diseases | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | Non Small Cell Lung... and other conditions

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer

Pain | Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
New York Stem Cell Foundation Research Institute
Laser and Skin Surgery Center of New York

Active, not recruiting

Biological Sample Collection for Research and Biobanking

Macular Degeneration | Cancer | Diabetes Mellitus, Type 1 | Parkinson Disease | Alzheimer Disease | ALS | Huntington Disease

United States
Abramson Cancer Center at Penn Medicine

Completed

Combination Therapy Using Lenalidomide (Revlimid)- Low Dose Dexamethasone and Rituximab for Treatment of Rituximab-Resistant, Non-Aggressive B-Cell Lymphomas

Follicular Lymphoma | Waldenstrom Macroglobulinemia | Mantle-Cell Lymphoma | Lymphoma, Small Lymphocytic | Marginal Zone B-Cell Lymphoma | MALT Lymphoma | Lymphoma of Mucosa-Associated Lymphoid Tissue

United States
National Cancer Institute (NCI)

Completed

M7824 in Subjects With HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Human Papilloma Virus | Vaginal or Penile Cancer

United States
Fred Hutchinson Cancer Center

Completed

Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant

Myelodysplastic Syndrome (MDS) | Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Acute Biphenotypic Leukemia | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Blasts Under 5 Percent of Bone Marrow...

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Maroteaux-Lamy Disease (BioMaroteaux) (BioMaroteaux)

Lung Diseases | Eye Abnormalities | Lysosomal Storage Disease | Macroglossia | Obstructive Sleep Apnoea

Germany, India, Sri Lanka, Egypt
Northwestern University

Completed

Genetics of Familial and Sporadic ALS (ALS)

Amyotrophic Lateral Sclerosis (ALS) | Lou Gehrig's Disease | Primary Lateral Sclerosis (PLS) | Familial Amyotrophic Lateral Sclerosis | ALS With Frontotemporal Dementia (ALS/FTD) | Motor Neuron Disease (MND) | Sporadic ALS (SALS)

United States
The Hospital for Sick Children

Active, not recruiting

International Rare Histiocytic Disorders Registry (IRHDR) (IRHDR)

Rare Histiocytic Disorders (RHDs) | Juvenile Xanthogranuloma (JXG) | Reticulohistiocytoma (Epithelioid Histiocytoma) | Xanthoma Disseminatum (XD) | Multicentric Reticulohistiocytosis (MRH) | Systemic Juvenile Xanthogranuloma | Erdheim-Chester Disease (ECD) | Multi-system Rosai-Dorfman Disease (RDD)

Canada, United States, Poland, Argentina, Austria, Czechia, Germany, Italy, Russian Federation, Spain
GOG Foundation
National Cancer Institute (NCI)

Completed

Cisplatin and Radiation Therapy With or Without Carboplatin and Paclitaxel in Patients With Locally Advanced Cervical Cancer

Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Stage IIA Cervical Cancer AJCC v7 | Stage IIB Cervical Cancer AJCC v6 and v7 | Stage IIIB Cervical Cancer AJCC v6 and v7 | Stage IVA Cervical Cancer AJCC v6 and v7 | Stage IB Cervical...

United States, Canada, Saudi Arabia, China, Singapore
EpicentRx, Inc.

Completed

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

Carcinoma, Non-Small-Cell Lung | Ovarian Epithelial Cancer | Neuroendocrine Tumors | Small Cell Carcinoma

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Medical and Psychosocial Issues in Adolescents and Young Adults With Colorectal Cancer

Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC... and other conditions

United States
Azienda Ospedaliero-Universitaria Consorziale Policlinico...
Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies; Istituti... and other collaborators

Completed

Establishment of the Human Intestinal and Salivary Microbiota Biobank - Kidney Diseases (BIOMIS-Nefro)

Autosomal Dominant Polycystic Kidney Disease (ADPKD) | IgA Nephropathy (IgAN) | Diabetic Kidney Disease (DKD) | Advanced-Chronic Kidney Disease (CKD)

Italy
Instituto Venezolano de Investigaciones Cientificas

Completed

Study to Verify the Effectiveness and Safety of Isothymol or Carvacrol Compound Against SARS-CoV-2 in COVID-19 Patients

COVID-19 | COVID-19 Pneumonia | COVID-19 Respiratory Infection | COVID-19 Acute Respiratory Distress Syndrome | COVID-19 Lower Respiratory Infection

Venezuela
University of Utah

Completed

Hypovitaminosis D in Neurocritical Patients

Stroke | Critical Illness | Craniocerebral Trauma | Brain Neoplasms | Seizures | Meningitis | Intracranial Hemorrhages | Spinal Cord Injuries | Intracranial Aneurysm | Vitamin d Deficiency

United States
University Health Network, Toronto
Sunnybrook Health Sciences Centre; University of Toronto; Hamilton Health Sciences... and other collaborators

Active, not recruiting

Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer (LS2)

Colorectal Neoplasms | Ovarian Neoplasms | Lynch Syndrome | Endometrial Neoplasms

Canada
Shanghai Public Health Clinical Center

Active, not recruiting

Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor

Renal Cell Carcinoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Non-small Cell Lung Cancer | Pancreas Cancer

China
Silverback Therapeutics

Withdrawn

A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid Tumors

Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Urothelial Carcinoma | Hormone Receptor-positive/HER2-negative Breast Cancer
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of Sanofi Pasteur's Combined Vaccine Given as a Three-Dose Primary Series at 2, 3,4 Months of Age and Followed by a Booster Dose Given at 16 to 17 Months of Age in Vietnamese Infants Who Previously Received a Dose of Hepatitis B Vaccine at Birth or Within 1 Week After Birth

Hepatitis B | Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Influenzae Type b

Vietnam
QuantalX Neuroscience

Completed

Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.

Healthy | Hemorrhage | Cognitive Impairment | Dementia | Fibromyalgia | TBI (Traumatic Brain Injury) | Cognitive Decline | Concussion, Brain | MS (Multiple Sclerosis) | Adhd | CVA | ABD | Mci

Israel
Fox Chase Cancer Center

Terminated

Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Liver Metastases | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States

Clinical Trials on SLL

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CROs in Congo

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