Clinical Trials on Saliva

Total 847 results

University Hospital, Strasbourg, France

Completed

Efficacy of Tocilizumab in Primary Sjögren's Syndrome. (ETAP)

Primary Sjögren's Syndrome (pSS)

France
National Institute of Allergy and Infectious Diseases...
Biogen; Autoimmunity Centers of Excellence

Terminated

Baminercept, a Lymphotoxin-Beta Receptor Fusion Protein, for Treatment of Sjögren's Syndrome

Primary Sjögren's Syndrome

United States
National Institute of Dental and Craniofacial Research...

Terminated

Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome Subjects

Xerostomia | Sjögren's Syndrome

United States
Sun Yat-sen University
Dalian Merro Pharmaceutical Co. Ltd

Unknown

A Phase II Clinical Trial on Comparison of Effectiveness and Safeness of Different Amifostine Regimens

Bone Marrow Diseases | Nasopharyngeal Neoplasms | Mucositis | Salivary Gland Diseases

China
Novartis Pharmaceuticals

Withdrawn

Study of Pharmacodynamic Effects of VAY736 in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome
University Hospital, Brest

Completed

Evaluation of the Reproducibility Inter-observer of the Ultrasound Anomalies of the Salivary Glands in Sjogren's Disease (ETREINTE)

Sjogren's Disease
NeuroHealing Pharmaceuticals Inc.
Michael J. Fox Foundation for Parkinson's Research

Completed

Safety and Efficacy Study of NH004 Films for Relief of Sialorrhea Symptoms in Parkinson's Disease Patients (NH004-2)

Sialorrhea Secondary to Parkinson's Disease

Argentina
University Hospital, Limoges

Completed

Neurotrophins Implications in Primary Sjögren Syndrome (Neuro-SGSp)

Primary Sjögren Syndrome

France
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Cord Blood Serum in the Treatment of Ocular Surface Diseases

Graft vs Host Disease | Sjogren's Disease

Italy
TorreyPines Therapeutics

Completed

Study of NGX267 Oral Capsules in Patients With Xerostomia Associated With Sjorgren's Syndrome

Sjogren's Syndrome | Xerostomia

United States
National Institute of Dental and Craniofacial Research...

Completed

Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek Cells

Sjogren's Syndrome | Graft vs Host Disease

United States
Resolve Therapeutics

Not yet recruiting

A Phase 2 Study of RSLV-132 in Females With Primary Sjögren's Syndrome

Primary Sjögren Syndrome
Babujinaya Cela

Not yet recruiting

Effect of Stellate Ganglion Block on Drooling in Parkinson's Syndrome

Parkinson's Syndrome
Amgen

Recruiting

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Sjögren's Syndrome (SS)

United States, Japan
RemeGen Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of Telitacicept in Subjects With Active Primary Sjogren's Syndrome

Primary Sjogren's Syndrome

China
Peking University People's Hospital

Recruiting

Low-dose Interleukin-2 and Rapamycin on sjögren's Syndrome

Sjögren's Syndrome

China
Novartis Pharmaceuticals

Recruiting

Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome (NEPTUNUS-2)

Sjogren Syndrome

Spain, Hungary, Germany, Canada, Greece, United Kingdom, Bulgaria, Japan, Colombia, United States, South Africa, Australia, China, Mexico, Israel, Lebanon, Taiwan, Argentina, Italy, France, Chile, Romania, India, Brazil, Poland, Slovakia, S...
Selcuk University

Recruiting

Evaluation of Hand Functions in Newly Diagnosed Primary Sjögren's Syndrome

Sjogren's Syndrome

Turkey
Gazi University

Not yet recruiting

The Profile of Fatigue and Discomfort - Sicca Symptoms Inventory

Primary Sjögren's Syndrome

Turkey
argenx
Iqvia Pty Ltd

Completed

A Study of the Safety and Effectiveness of Efgartigimod in Patients With Primary Sjögren's Syndrome (pSS) (rho)

Primary Sjögren's Syndrome

Belgium, Poland, Hungary, Netherlands
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sjögren's Syndrome (SS)

Sjögren's Syndrome

United States, France, Italy, Hungary, Poland, Argentina, India, Korea, Republic of, Mexico, Peru, Taiwan, United Kingdom
Stanford University

Withdrawn

Anti-BTLA Agonist Therapy in Subjects With Primary Sjogren's Syndrome

Primary Sjogren's Syndrome
University of Sao Paulo General Hospital

Active, not recruiting

N-acetylcysteine for Primary Sjögren's Syndrome (NACSS)

Sicca Syndrome | Sjögren Syndrome

Brazil
Novartis Pharmaceuticals

Active, not recruiting

Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships With Clinical Assessments.

Sjogren Syndrome

France
Sanofi

Completed

Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS) (phaethuSA)

Sjogren's Syndrome | Sjögren's Syndrome

Belgium, Taiwan, Korea, Republic of, United States, Argentina, Canada, Chile, France, Germany, Hungary, Mexico, Spain
Galapagos NV

Terminated

A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 12 Weeks in Adults With Active Primary Sjögren's Syndrome (pSS) (GLIDER)

Primary Sjögren Syndrome

Germany, Greece, Poland, Hungary, Ukraine
Bristol-Myers Squibb

Terminated

BMS-986325 in Healthy Participants and Participants With Primary Sjögren's Syndrome

Healthy Participants | Primary Sjögren's Syndrome

Germany, United States
Cairo University

Completed

the Effect of Mixture of Natural Products As Salivary Substitutes in Treatment Of Xerostomia (RCT)

Sjogren's Syndrome | Xerostomia

Egypt
Akdeniz University

Completed

Pelvic Floor Exercises in Patients With Sjögren's

Sjögren Syndrome | Sjögren

Turkey
Matthew C. Baker

Withdrawn

BAFF/IL-17 Bispecific Antibody Treatment in Subjects With Primary Sjogren's Syndrome (BAFF/IL-17)

Primary Sjogren's Syndrome

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of VAY736 in Patients With Primary Sjogren's Syndrome (pSS)

Primary Sjogren Syndrome

United States, Belgium, Italy, Austria, Israel, France, Germany, Hungary, Netherlands, United Kingdom, Japan, Portugal, Argentina, Spain, Taiwan, Russian Federation, Romania, Chile, Poland
University College, London
Cambridge University Hospitals NHS Foundation Trust; Sheffield Teaching Hospitals... and other collaborators

Active, not recruiting

Paediatric Sjögren Syndrome Cohort Study and Repository (PaedSSCoRe) (PaedSSCoRe)

Sjogren's Syndrome Childhood-onset

United Kingdom, Ireland
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics, and Preliminary Efficacy Study of CDZ173 in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

Hungary, Germany
UCB Celltech
PRA Health Sciences

Terminated

UCB Proof of Concept Study in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

France, Italy, Spain, Sweden, United Kingdom
HOB Biotech Group

Withdrawn

Clinical Performance of BioCLIA Ro60

Systemic Lupus Erythematosus | Sjogren's Syndrome

United States
National Institute of Dental and Craniofacial Research...

Completed

Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Volunteers Evaluating Oral Health Disparities as Determinants of Oral Health in a High-Risk Population

Sjogren's Syndrome | Oral Health

United States
Taipei Veterans General Hospital, Taiwan

Unknown

DNA Exome Sequencing TCM for Sjögren's Syndrome

Sjögren's Syndrome

Taiwan
Göteborg University

Completed

A Study of Flt3-Ligand Levels in Sjögrens Syndrome

Sjogrens Syndrome

Sweden
University of California, Los Angeles
University Medical Center Groningen; Oklahoma Medical Research Foundation

Completed

Salivary Biomarkers for Sjögren's Syndrome Detection

Sjögren's Syndrome

United States
MedImmune LLC
Amgen

Completed

A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

United States, Sweden, France, United Kingdom
University Hospital, Limoges

Completed

Primary Sjögren Syndrome (NeuroSenSS)

Primary Sjögren's Syndrome

France
Biogen

Completed

A Longitudinal, Observational Biomarker Study in Participants With Primary Sjogren's Syndrome

Healthy | Sjögren's Syndrome | Sicca Syndrome

United States
Derk Jan Jager

Unknown

Endoscopic Treatment of Salivary Glands Affected by Sjögren's Syndrome

Sjögren's Syndrome

Netherlands
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of Hepatitis A Vaccine Given at the Same Time of Measles, Mumps, Rubella Combined Vaccine

Measles | Hepatitis A | Rubella | Mumps

Turkey
The University of Texas Health Science Center at...
ALS Association; University of Kansas; Carolinas MDA Neuromuscular/ALS Center-Carolinas...

Completed

Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis | Sialorrhea

United States
Keio University

Unknown

Confocal Microscopy and Lacrimal Gland in Sjogren's Syndrome

Primary Sjogren's Syndrome

Japan
Pontificia Universidad Catolica de Chile
Formulario MAgistral Farmacias Ahumada

Completed

A Comparison of Orally Pilocarpine and Artificial Saliva in Xerostomy Treatment

Xerostomia | Primary Sjogren | Secondary Sjogren

Chile
University of Pisa

Recruiting

Ultra-High Frequency Ultrasonography in Sjögren's Syndrome (UltraSjögren)

Sjogren's Syndrome

Italy
University Tunis El Manar

Not yet recruiting

EVADRY® in the Treatment of Xerostomia in Sjögren's Syndrome (DRYLESS)

Sjogren's Syndrome
Amgen

Recruiting

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Sjogren's Syndrome

United States

Clinical Trials on Saliva

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Canada

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations