Clinical Trials on Serious Infection in United Kingdom

Total 51970 results

University of Southampton
University Hospital Southampton NHS Foundation Trust

Completed

Challenge of the Nasopharynx With Neisseria Lactamica Expressing the Meningococcal Protein Neisseria Adhesin A (NadA) (NadA-Lac4)

Meningitis, Bacterial | Neisseria Infection

United Kingdom
Oxford University Hospitals NHS Trust

Completed

Oral Versus Intravenous Antibiotics for Bone and Joint Infections (OVIVA B&J) (OVIVA)

Bone Infection | Joint Infection

United Kingdom
Imperial College London

Completed

To Assess Neuroinflammation and Neurocognitive Function in Patients With Acute Hepatitis C and Chronic HIV Co-Infection

HIV Infections | HIV | Acute Hepatitis C

United Kingdom
Portsmouth Hospitals NHS Trust
University of Portsmouth

Completed

Biofilm Composition as a Predictive Biomarker for Prosthetic Joint Infection (Biofilms)

Joint Infection

United Kingdom
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Recruiting

A Controlled Phase 2a Study to Evaluate the Efficacy of EDP-323 Against Respiratory Syncytial Virus Infection in a Virus Challenge Model

RSV Infection

United Kingdom
AiCuris Anti-infective Cures AG

Completed

Thorough QT/QTc of Pritelivir in Healthy Subjects

HSV Infection

United Kingdom
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Completed

A Phase 2a Study to Evaluate EDP-938 in the Virus Challenge Model

RSV Infection

United Kingdom
Hvivo
GlaxoSmithKline

Completed

RSV Study in Adults 60 to 75 Years of Age

RSV Infection

United Kingdom
Imperial College London

Recruiting

The Impact of Age on Adaptive Immunity in Adults Infected With Respiratory Syncytial Virus (INFLAMMAGE)

RSV Infection

United Kingdom
Bavarian Nordic

Completed

Phase 2a Study of MVA-BN-RSV Vaccination and RSV Challenge in Healthy Adults

RSV Infection

United Kingdom
Meissa Vaccines, Inc.
Hvivo

Completed

Human Challenge Study to Evaluate the Efficacy of MV-012-968 Vaccine

RSV Infection

United Kingdom
Alios Biopharma Inc.

Completed

A Phase 2a Study to Evaluate ALS-008176 in the Virus Challenge Model

Respiratory Syncytial Virus Infections

United Kingdom
Novartis
Novartis Vaccines

Completed

Persistence of Immune Response After Vaccination With MCC

Prevention of Meningococcal Infection

United Kingdom
Novartis Vaccines

Completed

Persistence of Antibodies and Kinetics of B Cell Response in Healthy Children After Vaccination With MCC Vaccine

Prevention of Meningococcal Infection

United Kingdom
Novartis
Novartis Vaccines

Completed

Kinetics of B Cell Response in Infants Menjugate Vaccination

Prevention of Meningococcal Infection

United Kingdom
Thirty Respiratory Limited

Withdrawn

PREvent Viral Exposure and Transmission Study: a COVID-19 (SARS-CoV-2) PEP Study (PREVENT) (PREVENT)

Respiratory Tract Diseases | COVID-19 Respiratory Infection | Respiratory Viral Infection

United Kingdom
St George's, University of London

Completed

Understanding COVID-19 Infection in Pregnant Women and Their Babies (periCOVID)

Pregnancy Related | Corona Virus Infection | Breastfeeding | Neonatal Infection

United Kingdom
Pfizer

Completed

A Study to Learn About the Effects of Multiple Doses of Sisunatovir on People With Respiratory Syncytial Virus (RSV) Infection

Respiratory Syncytial Virus Infections

United Kingdom
Nottingham University Hospitals NHS Trust

Terminated

Ursodeoxycholic Acid in C. Difficile Infection

Clostridioides Difficile Infection

United Kingdom
Barts & The London NHS Trust

Unknown

Novel Biomarkers to Predict Outcome in Clostridium Difficile Infection

Clostridium Difficile Infection

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Imperial College London; Barts & The London NHS Trust; University of Cambridge; Imperial College Healthcare NHS Trust

Completed

Biomarkers of Acute Serious Illness in Children (BASIC)

Critical Illness | Children, Only | Infection, Mixed

United Kingdom
Pfizer

Completed

To Investigate the Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI)

Bacterial Infections | Complicated Infection

United Kingdom
Janssen Sciences Ireland UC

Completed

Study to Evaluate Antiviral Activity, Safety, and Pharmacokinetics of Repeated Doses of Orally Administered JNJ 53718678 Against Respiratory Syncytial Virus Infection.

Respiratory Syncytial Virus Infections

United Kingdom
Imperial College London

Completed

Predicting Severity and Disease Progression in Influenza-like Illness (Including COVID-19) (PREDICT-ILI)

RNA Virus Infections | Respiratory Tract Infections | Covid19 | Influenza | Infection, Bacterial | SARS (Severe Acute Respiratory Syndrome) | Respiratory Viral Infection | Infection Viral

United Kingdom
Chelsea and Westminster NHS Foundation Trust

Unknown

Evaluating Clinical Parameters of COVID-19 in Pregnancy (COpregVID)

COVID-19 | COVID-19 Infection | 2019 Novel Coronavirus Infection

United Kingdom
Imperial College London
Sense Biodetection Limited

Unknown

Evaluation of a Single Use Point of Care Device for the Diagnosis of Respiratory Pathogens (SIMPLIFI)

Enterovirus Infections | Respiratory Syncytial Virus Infections | Human Influenza | Rhinoviral Infections | Metapneumovirus Infection | Parainfluenzae Viral Infections

United Kingdom
Valneva Austria GmbH

Withdrawn

Immune Response in IXIARO Batch JEV09L37 Recipients Before and After Revaccination

Japanese Encephalitis

United Kingdom
University of Liverpool

Completed

Flavivirus Cross-priming Potential of IMOJEV (FlaviPrime)

Japanese Encephalitis

United Kingdom
University of Oxford

Completed

The Microbiology of Pleural Infection (TORPIDS)

Pleural Infection | Pleural Infection Bacterial

United Kingdom
St George's, University of London
Antibiotic Research UK

Recruiting

Neonatal Antimicrobial Resistance and Outcome (neoAMRO)

Neonatal Infection

United Kingdom
University College, London
Public Health England

Completed

COG-UK Project Hospital-Onset COVID-19 Infections Study (COG-UK HOCI)

Coronavirus Infection | Covid-19 | SARS-CoV 2 | Coronavirus | Nosocomial Infection

United Kingdom
Imperial College London
Wellcome Trust

Completed

The Development of a Human Model of Respiratory Syncytial Virus Infection

Respiratory Syncytial Virus Infections | Respiratory Viral Infections

United Kingdom
University of Oxford

Active, not recruiting

RESCEU: Defining the Burden of RSV Disease

Respiratory Syncytial Virus Infections | RSV Infection

United Kingdom
Chelsea and Westminster NHS Foundation Trust

Recruiting

PHenotyping patiENts Admitted to Hospital With cOvid-19 Infection and idenTifYing Prognostic markErs (PHENOTYPE)

COVID-19 | Corona Virus Infection | Coronavirus | 2019 Novel Coronavirus Infection | 2019nCoV

United Kingdom
Royal Marsden NHS Foundation Trust
St George's, University of London; Mologic Ltd; The Royal Marsden Cancer Charity and other collaborators

Completed

Cancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19) (CARDS)

Coronavirus Infection | Cancer | Infectious Disease

United Kingdom
Destiny Pharma Plc

Completed

Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)

Staphylococcal Infection

United Kingdom
University of Edinburgh
Medical Research Council; ISLACARE LTD (12108076)

Recruiting

ImplementatioN of Remote Surgical wOund Assessment During the coviD-19 pandEmic (INROADE)

Surgical Site Infection

United Kingdom
Biota Pharma Europe Limited

Completed

Safety, Efficacy and Pharmacokinetics of BTA-C585 in a RSV Viral Challenge Study

Respiratory Syncytial Virus (RSV) Infection

United Kingdom
Cell Medica Ltd
Technology Strategy Board, United Kingdom

Completed

Safety Study of ADV-specific T-cells in Paediatric Patients Post Allo-HSCT (ASPIRE)

ADV Infection Post Allo-HSCT

United Kingdom
Scynexis, Inc.
Inncelerex

Completed

ADME Study of [14C]-Ibrexafungerp in Healthy Male Subjects

Fungal Infection

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Hvivo

Completed

SARS-CoV-2 Human Challenge Characterisation Study

COVID-19 | Covid19 | Corona Virus Infection | SARS-CoV Infection | Coronavirus

United Kingdom
Nitric BioTherapeutics, Inc

Terminated

Clinical Trial on the Reduction of Methicillin Resistant Staphylococcus Aureus (MRSA)

Skin Ulcers | Methicillin-resistant Staphylococcus Aureus Infection

United Kingdom
St George's, University of London
University College, London

Recruiting

Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK) (MD-PK)

Sepsis | Critical Illness | Septic Shock | Bacteremia | Infection, Bacterial | Antibiotic Side Effect | Antibiotic Resistant Infection | Adult Children

United Kingdom
University of Derby
University of Exeter; University Hospitals of Derby and Burton NHS Foundation... and other collaborators

Not yet recruiting

An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID. (ERASE-LC)

COVID-19 | SARS-CoV-2 Infection

United Kingdom
MedImmune LLC

Terminated

Intranasal Challenge of Healthy Adults With Respiratory Syncytial Virus (RSV)

RSV Infection

United Kingdom
Liverpool School of Tropical Medicine
University of Oxford

Recruiting

Using BCG Vaccine to Understand Tuberculosis Infection (Pilot BCG CHIM)

Tuberculosis

United Kingdom
University of Leeds
GlaxoSmithKline; AstraZeneca; Sanofi Pasteur, a Sanofi Company; BioMérieux; Da Volterra and other collaborators

Completed

COMBACTE-CDI Understanding the Burden of C. Difficile Infection (COMBACTE-CDI)

Clostridium Difficile Infection

United Kingdom
Imperial College London

Completed

Anticoagulation in Liver Fibrosis in Patients With Hepatitis C Virus Infection

Liver Fibrosis

United Kingdom
St George's, University of London
University of Nottingham; Medical Research Council; Public Health England

Recruiting

Development of a Serocorrelate of Protection Against Invasive Group B Streptococcus Disease (iGBS3)

Streptococcus Agalactiae Infection

United Kingdom
BioCryst Pharmaceuticals
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Phase 1 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BCX4430

Ebola Virus Infection | Filovirus Infections

United Kingdom

Clinical Trials on Serious Infection in United Kingdom

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