Clinical Trials on Severe Systemic Sclerosis in Netherlands

Total 5452 results

UMC Utrecht
Boehringer Ingelheim; ZonMw: The Netherlands Organisation for Health Research... and other collaborators

Recruiting

Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis (UPSIDE)

Systemic Sclerosis | Scleroderma, Diffuse | Mycophenolate Mofetil | Scleroderma | Autologous Stem Cell Transplantation | Cyclophosphamide | Systemic Scleroses, Diffuse | Treatment Strategy

Italy, Switzerland, Netherlands, Sweden, United Kingdom
Amsterdam UMC, location VUmc

Recruiting

Discontinuing Disease-modifying Therapies in Stable Relapsing - Onset Multiple Sclerosis (DOT-MS). (DOT-MS)

Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive

Netherlands
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

An Observational Study for the Assessment of Adherence, Effectiveness and Convenience of Rebif® Treatment in Relapsing Multiple Sclerosis Patients Using RebiSmart™. (SMART)

Multiple Sclerosis, Relapsing-Remitting

Netherlands
Amphia Hospital
Sanofi; TEVA Pharmachemie

Unknown

Optical Coherence Tomography: Glatiramer in Clinically Isolated Syndrome or Early Relapsing Remitting Multiple Sclerosis (MS) (OCTIMS)

Multiple Sclerosis

Netherlands
UMC Utrecht
Radboud University Medical Center; University Medical Center Groningen; Royal... and other collaborators

Recruiting

Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME)

Systemic Sclerosis

Netherlands
Amsterdam UMC, location VUmc
Stichting Treatmeds

Recruiting

Non-inferiority Study of Rituximab Compared to Ocrelizumab in Relapsing MS (Noisy Rebels)

Nervous System Diseases | Multiple Sclerosis | Demyelinating Autoimmune Diseases, CNS | Autoimmune Diseases of the Nervous System | Demyelinating Diseases | Multiple Sclerosis, Relapsing-Remitting

Netherlands
Gert-Jan Braunstahl
Genzyme, a Sanofi Company

Completed

Real Life Experience Survey of Dupilumab in the Netherlands (RELYonDupi)

Severe Asthma

Netherlands
Amsterdam UMC, location VUmc

Recruiting

B Cell Tailored Ocrelizumab Versus Standard Ocrelizumab in Relapsing Remitting Multiple Sclerosis (BLOOMS)

Multiple Sclerosis, Relapsing-Remitting

Netherlands
UMC Utrecht
Princess Beatrix Muscle Foundation

Completed

Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Netherlands
University Medical Center Groningen
University of Groningen

Recruiting

The MS-CEBA Study: Determining Cognitive, Energetic, Behavioural and Affective (CEBA) Profiles in Multiple Sclerosis (MS-CEBA)

Multiple Sclerosis

Netherlands
Maastricht University Medical Center
Orbis Medical Centre

Completed

Vitamin D3 Supplementation and the T Cell Compartment in Multiple Sclerosis (MS)

Multiple Sclerosis

Netherlands
Amsterdam UMC, location VUmc

Recruiting

Multiple Sclerosis Self Monitoring Study (MSSM)

Multiple Sclerosis

Netherlands
Allergan

Completed

Post-Market Study of JUVÉDERM VOLIFT™ With Lidocaine for the Correction of Nasolabial Folds

Moderate to Severe Nasolabial Folds

Germany, Netherlands
Leiden University Medical Center
The International Society of Travel Medicine

Recruiting

Yellow Fever Human Infection Model With YF-17D (YF-INFECT)

Yellow Fever

Netherlands
Onze Lieve Vrouwe Gasthuis

Unknown

Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis

Severe Sepsis | Microcirculation

Netherlands
Amsterdam UMC, location VUmc
UMC Utrecht; Dijklander Ziekenhuis; Medical Center Haaglanden; Elisabeth-TweeSteden... and other collaborators

Completed

Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's) (SAPS)

Sepsis | Septic Shock | Severe Sepsis

Netherlands
UMC Utrecht
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic Sclerosis (MANUS)

Systemic Sclerosis | Digital Ulcer

Netherlands
Medical Centre Leeuwarden

Completed

The Effect of Ketanserin on the Microcirculation in Sepsis

Septic Shock | Severe Sepsis

Netherlands
Zuyderland Medisch Centrum
Scannexus

Active, not recruiting

Ultra-high-field Brain MRI in Multiple Sclerosis (ULTIMS)

Multiple Sclerosis

Netherlands
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Onze...

Recruiting

Transmural Collaborative Care Model for CVRM and Medication Review for Patients Using Antipsychotics (TACTIC)

Mental Disorders, Severe

Netherlands
Radboud University Medical Center

Terminated

The Effect of Intensive Controlled Exercise in the Early Stages of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Netherlands
Erasmus Medical Center

Unknown

Peripheral Perfusion Targeted Fluid Management

Sepsis | Severe Sepsis

Netherlands
Newron Sweden AB

Terminated

A follow-on Study to Assess Long-term Safety and Tolerability of i.c.v Administration of sNN0029 in Patients With ALS

Amyotrophic Lateral Sclerosis

Belgium, Netherlands
Newron Sweden AB

Terminated

A Safety Study of sNN0029 Administration Via Intracerebroventricular Route to Patients With ALS

Amyotrophic Lateral Sclerosis

Belgium, Netherlands
Zoé van Kempen

Completed

COVID-19 and SARS-CoV-2 Antibodies in Multiple Sclerosis Patients (COMS-19)

Multiple Sclerosis

Netherlands
Amsterdam UMC, location VUmc

Completed

The Wearing-off Phenomenon of Ocrelizumab in Patients With Multiple Sclerosis (WOC)

Multiple Sclerosis

Netherlands
Amsterdam UMC, location VUmc
National MS Foundation, The Netherlands; Voeding Leeft

Recruiting

Lifestyle Intervention for Patients With Multiple Sclerosis (LIMS)

Multiple Sclerosis

Netherlands
Academic MS Center Limburg

Terminated

Vitamin D3 and the Stress-axis in MS

Multiple Sclerosis

Netherlands
Amsterdam UMC, location VUmc
Erasmus Medical Center; St. Antonius Hospital; Rijnstate Hospital; OLVG; Prothya...

Completed

Towards Personalized Dosing of Natalizumab in Multiple Sclerosis (PDNMS)

Multiple Sclerosis

Netherlands
Verge Genomics

Recruiting

A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Canada, Netherlands
GGZ Centraal

Completed

Multidisciplinary Lifestyle-enhancing Treatment for People With Severe Mental Illness in Sheltered Housing Facilities

Mental Disorders, Severe | Lifestyle

Netherlands
Radboud University Medical Center

Completed

Effects of Alkaline Phosphatase on Renal Function in Septic Patients

Shock | Septic | Severe

Netherlands
Radboud University Medical Center

Unknown

The Effect of High Dose Methylprednisolone on Nailfold in Early Systemic Sclerosis ( SSc )

Systemic Sclerosis | Raynaud Phenomena

Netherlands
BBB-Therapeutics B.V.

Terminated

Safety, Pharmacokinetics and Pharmacodynamics Study With 2B3-201 in Healthy Subjects and Multiple Sclerosis(MS) Patients

Multiple Sclerosis | Healthy Volunteers

Netherlands
Biogen

Completed

Avonex (Interferon-beta-1a) and Avonex Plus Methylprednisolone for the Treatment of Relapsing-remitting MS

Relapsing-remitting Multiple Sclerosis

Belgium, Denmark, Finland, Netherlands, Norway, Sweden, Switzerland, United Kingdom
Amsterdam UMC, location VUmc
Genzyme, a Sanofi Company; Universiteit Leiden; Personal Fitness Nederland; MS... and other collaborators

Recruiting

Don't be Late! Postponing Cognitive Decline and Preventing Early Unemployment in People With Multiple Sclerosis (DBL)

Multiple Sclerosis

Netherlands
Actelion

Completed

Bosentan in Systemic Sclerosis (HOME)

Systemic Sclerosis | Digital Ulcers

Netherlands
GGZ Centraal
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Evaluation of Combined Support for the Ambulatory Lifestyle Intervention (GOAL!)

Lifestyle | Severe Mental Illness

Netherlands
Maastricht University Medical Center
National Cattlemen's Beef Association

Completed

Effects of Beef Protein Consumption on Energy Intake

Obesity | Severe Overweight

Netherlands
Amsterdam UMC, location VUmc

Recruiting

Clemastine Fumarate as Remyelinating Treatment in Internuclear Ophthalmoparesis and Multiple Sclerosis (RESTORE)

Multiple Sclerosis | Internuclear Ophthalmoplegia

Netherlands
University Medical Center Groningen

Recruiting

Optimizing INITIation of Non-invasive Ventilation in ALS Patients (INITIALS)

Amyotrophic Lateral Sclerosis

Netherlands
The University of Queensland
King's College London; UMC Utrecht; Julius Clinical; FightMND

Completed

Targeting Metabolic Flexibility in Amyotrophic Lateral Sclerosis (ALS) (MetFlex)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

Netherlands, United Kingdom, Australia
Retrotope, Inc.

Recruiting

RT001 in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Netherlands, Estonia, Latvia, Sweden
HAN University of Applied Sciences
FrieslandCampina; HAS Hogeschool; Centre of Expertise Food (CoE Food); Sligro

Completed

Increase Protein Intake of Older Meal Service Clients With Readymade Protein-rich Meals and Foods (ConsuMEER)

Malnutrition; Protein | Protein Malnutrition

Netherlands
University of Groningen
Lentis Psychiatric Institute; GGZ Friesland; Stichting Cosis

Not yet recruiting

Cognitive Remediation and Transcranial Direct Current Stimulation in Severe Mental Illness (SMI) (HEADDSET+)

Severe Mental Illness

Netherlands
Erasmus Medical Center

Unknown

The Cognitive Variability in NF1 and TSC Monozygotic Twins (COVANTT)

Tuberous Sclerosis Complex | Neurofibromatosis Type I

Netherlands
Tilburg University
Stichting tot steun VCVGZ; Trimbos-institute (also primary organization conducting... and other collaborators

Active, not recruiting

Investigating the Meaning and (Cost-)Effectiveness of Dutch Recovery Colleges

Severe Mental Illness | Mental Vulnerabilities

Netherlands
Delta Crystallon BV

Completed

Safety and Dose-finding Study of DC-TAB in Healthy Subjects

Multiple Sclerosis

Netherlands
Erasmus Medical Center
Utrecht University

Unknown

Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex (RAPIT)

Tuberous Sclerosis Complex | TSC Related Cognitive Disability | TSC Related Autism | TSC Related Learning Problems

Netherlands
University Medical Center Groningen

Not yet recruiting

TENS in Persons With MS

Multiple Sclerosis

Netherlands

Clinical Trials on Severe Systemic Sclerosis in Netherlands

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