Clinical Trials on Severe Sepsis

Total 6598 results

Sanofi Pasteur, a Sanofi Company

Completed

Study of a Booster Dose of a Tetravalent Dengue Vaccine in Subjects Who Previously Completed the 3-dose Schedule

Dengue Fever | Dengue Hemorrhagic Fever

Brazil, Colombia, Honduras, Mexico, Puerto Rico
Sanofi Pasteur, a Sanofi Company

Completed

Prospective Dengue Seroprevalence Study in 5 to 10 Year-old Children

Dengue | Dengue Fever | Dengue Hemorrhagic Fever

India
Region Örebro County

Unknown

Quantification of Bacterial DNA in Sepsis

Sepsis | Septic Shock | Sepsis Bacterial

Sweden
Hospital General de Ciudad Real
University of Castilla-La Mancha

Terminated

Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension (HYSATESS-p)

Septic Shock | Sepsis-associated Hypotension

Spain
Sanofi

Completed

Immunogenicity and Safety of Three Formulations of Dengue Vaccines in Healthy Adults Aged 18 to 45 Years in the US

Dengue Fever | Dengue Hemorrhagic Fever | Dengue Virus

United States
Sanofi

Completed

Study of ChimeriVax™ Dengue Tetravalent Vaccine in Adult Subjects

Dengue | Dengue Fever | Dengue Hemorrhagic Fever | Dengue Virus

Australia
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of Sanofi Pasteur's CYD Dengue Vaccine in Healthy Children and Adolescents in Latin America

Dengue | Dengue Fever | Dengue Hemorrhagic Fever | Dengue Virus

Puerto Rico, Colombia, Mexico, Honduras
Beckman Coulter, Inc.
Saint-Louis Hospital, Paris, France; Hôpital Raymond Poincaré

Completed

Leukocyte MOrphology and CORticosteroids Response in SEPtic Patients (MOCORSEP) (MOCORSEP)

Sepsis | Septic Shock | Infection | Sepsis Syndrome

France
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Role of Vitamin D in Prevention of Dengue Haemorrhagic Fever and Dengue Shock Syndrome

Dengue Fever

Bangladesh
Hallym University Medical Center

Unknown

4G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic Shock

Severe Sepsis
Assistance Publique - Hôpitaux de Paris

Completed

Ilomedin in Septic Shock With Persistent Microperfusion Defects (I-MICRO) (I-MICRO)

Septic Shock Hyperdynamic

France
Southeast University, China
Baxter Healthcare Corporation

Completed

A Multiple Centre, Cohort Study of New CRRT Membranes oXiris for Patients With Septic Shock

Acute Kidney Injury Due to Sepsis (Disorder)

China
Eisai Inc.

Completed

A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis

Sepsis | Shock, Septic | Infection | Sepsis Syndrome | Septicemia

United States
Institute of Tropical Medicine, Belgium
World Health Organization; Institut National de Recherche Biomédicale. Kinshasa... and other collaborators

Terminated

Piloting Clinical Bacteriology in the Ebola Virus Disease Care Response (Bact_EVD)

Ebola Virus Disease | Bloodstream Infection | Sepsis Bacterial

Congo, The Democratic Republic of the
Petrovsky National Research Centre of Surgery

Recruiting

Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS) (РМХ vs SS)

Multiple Organ Dysfunction With Severe Endotoxemia

Russian Federation
Oxford University Clinical Research Unit, Vietnam
Children's Hospital Number 1, Ho Chi Minh City, Vietnam; Hospital for Tropical... and other collaborators

Completed

Laboratory Diagnosis and Prognosis of Severe Dengue

Dengue Fever

Vietnam
University Hospital, Basel, Switzerland

Completed

Pathogenesis and Cerebrovascular Manifestations of Septic Encephalopathy

Sepsis

Switzerland
Sanofi Pasteur, a Sanofi Company

Completed

Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Subjects

Dengue Fever | Dengue Hemorrhagic Fever | Dengue Virus | Dengue Disease

Vietnam
Sanofi Pasteur, a Sanofi Company

Completed

Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Peruvian Children Aged 2 to 11 Years

Dengue Fever | Dengue Hemorrhagic Fever | Dengue Virus | Dengue Diseases

Peru
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Gardasil®

Dengue Fever | Dengue Hemorrhagic Fever | Human Papillomavirus Disease

Malaysia
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Cervarix®

Dengue Fever | Dengue Hemorrhagic Fever | Human Papillomavirus Disease

Mexico
Sanofi Pasteur, a Sanofi Company

Completed

Study of Sanofi Pasteur's CYD Dengue Vaccine in Healthy Subjects in Singapore

Dengue Fever | Dengue Hemorrhagic Fever | Dengue Virus | Dengue Diseases

Singapore
University of Zurich

Completed

The Effects of a Polyethyleneimine-coated Membrane (oXiris™) for Hemofiltration Versus Polymyxin B- Immobilized Fibre Column (Toraymyxin™) for Hemoperfusion on Endotoxin Activity and Inflammatory Conditions in Septic Shock- A Randomized Controlled Pilot Study (ENDoX-study)

Patients in Septic Shock

Switzerland
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Formulations of Dengue Vaccines in Healthy Flavivirus-Naïve Adults

Dengue Fever | Dengue Hemorrhagic Fever | Dengue Virus | Dengue Diseases

Mexico
Assiut University

Unknown

Early Diagnosis of Neonatal Sepsis

Sepses, Neonatal
Centre Hospitalier Universitaire Dijon

Completed

Study of Subcutaneous Interstitial Pressure During Sepsis (PISEP)

Patients With Septic Shock

France
Cliniques universitaires Saint-Luc- Université...

Terminated

Early Physical Therapy in Patients With Sepsis (EARTH-ICU)

Multiple Organ Dysfunction Syndrome | SEPTIC SHOCK | SEPSIS SYNDROME

Belgium
Mansoura University

Not yet recruiting

Dexmedetomidine and Vasopressin in Septic Shock (DecatSepsis-2)

Sepsis | Septic Shock
Kingman Regional Medical Center
La Jolla Pharmaceutical Company

Recruiting

Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock

Sepsis | Systemic Inflammatory Response Syndrome | Shock | Septic Shock

United States
Noha Mansour

Recruiting

Midodrine Effect on the Mortality Rates in Septic Shock Patients

Septic Shock

Egypt
CHU de Reims

Recruiting

Cardiovascular Effects of Norepinephrine

Septic Shock

France
Assiut University

Not yet recruiting

Serum Rennin Kinetics Versus Serum Lactate Kinetics as Predictors of Mortality in Septic Shock Patients

Septic Shock
Cairo University

Not yet recruiting

a Novel Index for Tissue Perfusion in Predicting Outcome in Patients With Septic Shock

Septic Shock

Egypt
Amany Mousa Salama Muhammed

Not yet recruiting

Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic Patients

Septic Shock
Pontificia Universidad Catolica de Chile
Erasmus Medical Center; Hospital do Coracao; Fundacion Clinica Valle del Lili

Recruiting

Hemodynamic Phenotype and Capillary Refill Time-targeted Resuscitation Strategy (A2)

Septic Shock

Chile
Insel Gruppe AG, University Hospital Bern

Recruiting

Protocolised Early De-Resuscitation in Septic Shock (REDUCE) (REDUCE)

Septic Shock

Switzerland
Saptadi Yuliarto

Recruiting

Septic Shock Management Guided by Ultrasound: SEPTICUS Trial

Septic Shock

Indonesia
Pontificia Universidad Catolica de Chile
Fondo Nacional de Desarrollo Científico y Tecnológico, Chile

Not yet recruiting

Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients (AUSTRALIS)

Septic Shock

Chile
Hospital da Luz, Portugal

Recruiting

Assessment of Microcirculatory Dysfunction in Septic Shock Patients by OCTA (SshOCTA)

Septic Shock

Portugal
Burdenko Neurosurgery Institute

Recruiting

Safety and Efficiency of Combined Extracorporeal Blood Purification in Neurosurgical ICU. Prospective RCT (NEUROCOMB)

Septic Shock

Russian Federation
Carilion Clinic
Provepharm Life Solutions

Recruiting

Methylene Blue as a Third-line Vasopressor in Septic Shock

Septic Shock

United States
Universitätsklinikum Hamburg-Eppendorf
CytoSorbents, Inc

Recruiting

Adjuvant Therapy With CytoSorb in Refractory Septic Shock (ACYSS)

Septic Shock

Germany
Efferon JSC
Ligand Research, LLC

Completed

Lipopolysaccharide Adsorption at Septic Shock (LASSO)

Septic Shock

Russian Federation
University Hospital, Brest

Completed

Guided Fluid-balance Optimization With Mini-fluid chALlenge During Septic Shock (GOAL)

Septic Shock

France
Adrenomed AG

Completed

Treatment of Patients With Early Septic Shock and Bio-Adrenomedullin(ADM) Concentration > 70 pg/ml With ADRECIZUMAB (AdrenOSS-2)

Septic Shock

France, Belgium, Germany, Netherlands
Hospital Sirio-Libanes
Ministry of Health, Brazil; PROADI-SUS

Terminated

Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock

Sepsis | Septic Shock

Brazil
University of Virginia

Withdrawn

Midodrine in the Recovery Phase of Septic Shock

Septic Shock

United States
Guangdong Second Provincial General Hospital

Completed

Lung Ultrasound-guided Fluid Resuscitation in Neonatal Septic Shock (LUGFRINSS)

Septic Shock

China
Rennes University Hospital
H.A.C. PHARMA

Suspended

Hemodynamics Effects of Fludrocortisone on the Pressor Response to Noradrenaline Septic Shock Patients (FLUDROSEPSIS)

Septic Shock

France
Assistance Publique - Hôpitaux de Paris
Baxter Healthcare Corporation

Active, not recruiting

Pilot Phase II Study: Hemodynamic Tolerance and Anti-inflammatory Effects of Esmolol During the Treatment of Septic Shock (THANE)

Septic Shock

France

Clinical Trials on Severe Sepsis

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Algeria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations