Clinical Trials on Skin Wrinkling

Total 51061 results

West Virginia University

Completed

Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS)

COVID-19 | Acute Respiratory Distress Syndrome

United States
National Cancer Institute (NCI)

Terminated

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

Carcinoma, Renal Cell | Gastrointestinal Stromal Tumors | Pheochromocytoma | Paraganglioma | Renal Neoplasms

United States
Sarcoma Oncology Research Center, LLC
Aadi Bioscience, Inc.

Completed

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Ewing Sarcoma | Non Small Cell Lung Cancer | Chordoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | PEComa | Desmoid Tumor | Epithelioid Sarcoma | Squamous Cell Carcinoma | MTOR Activating Mutation

United States
Centre Hospitalier Régional d'Orléans

Completed

Latest Imaging SPECT System Evaluation Phase 1 (LISSE1)

Heart Diseases | Neoplasms | Kidney Diseases | Parathyroid Diseases | Thyroid Diseases | Parkinsonian Disorders | Dementia | Pulmonary Embolism | Rheumatic Disease

France
Massachusetts General Hospital
ALS Association

Completed

Electronic-health Application To Measure Outcomes REmotely Clinical Trial (EAT MORE)

Parkinson's Disease | Amyotrophic Lateral Sclerosis | Weight Loss | Cachexia | Huntington's Disease | Neurodegenerative Disease

United States
Fondazione IRCCS Istituto Nazionale dei Tumori,...
University of Milan

Unknown

Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain Metastases (OPTIMAL)

Melanoma | Breast Cancer | Lung Cancer | Brain Metastases

Italy
Chang Gung Memorial Hospital

Completed

18F-PM-PBB3 PET Study in Tauopathy Including Alzheimer's Disease, Other Dementias and Normal Controls

Frontotemporal Dementia | Progressive Supranuclear Palsy | Alzheimer's Disease | Vascular Cognitive Impairment | Cortical Basal Syndrome

Taiwan
Centre Hospitalier Universitaire, Amiens

Terminated

Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies (GREFEXII)

Stroke | Parkinson Disease | Alzheimer Disease | Traumatic Brain Injury | Huntington Disease | Frontal Dementia

France
University of Minnesota
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Longitudinal Studies of Brain Structure and Function in MPS Disorders

Mucopolysaccharidosis Type I | Mucopolysaccharidosis Type II | Mucopolysaccharidosis Type VI | Mucopolysaccharidosis Type IV | Mucopolysaccharidosis Type VII

United States, Canada
Massachusetts General Hospital
The Children's Tumor Foundation

Completed

Resiliency Training for Patients With NF2 Via Videoconferencing With Skype

Neurofibromatosis 2

United States
Johann Wolfgang Goethe University Hospital
CSL Behring

Completed

Susceptibility to Infections in Ataxia Telangiectasia

Infections | Lung Disease | Immunodeficiency | Ataxia Telangiectasia
DePuy International

Completed

A Randomised Single Centre Study to Compare the Long-term Wear Characteristics of Marathon™ and Enduron™ Polyethylene Cup Liners in Primary Total Hip Replacement

Osteoarthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

New Zealand
University of Florida

Withdrawn

Proton Radiation Therapy for Spinal Tumors (NF01)

Neurofibroma | Nerve Sheath Tumors
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Withdrawn

Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer

Sarcoma | Pain | Lymphoma | Ovarian Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Cachexia | Melanoma (Skin)
Centre Hospitalier Universitaire, Amiens

Completed

Assessment of Social-emotional Functioning in Neurological Diseases (Emotion)

Stroke | Parkinson's Disease | Alzheimer Disease | Huntington Disease | Lewy Body Dementia

France
Children's Hospital Medical Center, Cincinnati
Novartis Pharmaceuticals

Completed

RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM

Tuberous Sclerosis | Lymphangioleiomyomatosis

United States
Triemli Hospital

Completed

A Cohort Study of Patients Treated With Brachytherapy for Selected Desmoid Patients in Gardner Syndrome

Colorectal Carcinoma | Desmoid Tumor | Gardner Syndrome
Parker, William H., M.D.
Ethicon, Inc.

Completed

Examining the Long-Term Risks of Oophorectomy

Stroke | Cancer | Breast Cancer | Death | Ovarian Cancer | Coronary Heart Disease | Hip Fracture

United States
Children's Hospital Medical Center, Cincinnati
The LAM Foundation; Tuberous Sclerosis Alliance

Completed

Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM

Tuberous Sclerosis | Lymphangioleiomyomatosis

United States
Light Sciences LLC

Completed

Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors

Sarcoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Rectal Cancer | Pelvic Cancer | Mouth Cancer | Liver Metastasis

United States
NeurogesX

Terminated

An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain

HIV Infections | Pain | Diabetes Mellitus | Diabetic Neuropathies | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster | Polyneuropathies
Peking University First Hospital

Recruiting

Establishment of a Multidimensional Prediction Model for the Natural Course of VHL Disease-related Renal Cell Carcinoma

Renal Cell Carcinoma | VHL Syndrome

China
David Franco Castellanos
Jesús Ángel Seco Calvo; Javier Tejada Garcia

Not yet recruiting

How Does Pianistic Musical Training Influence the Development of Alzheimer's Disease?

Dementia | Neurologic Disorder | Dementia, Vascular | Cognitive Decline | Dementia, Mixed | Dementia With Lewy Bodies | Neurologic Dysfunction | Dementia of Alzheimer Type | Neurologic Deficits | Dementia Frontal

Spain
Sun Yat-sen University

Not yet recruiting

Myeloprotection With Trilaciclib in Pan-cancer Population

Cervical Cancer | Breast Cancer | Non-Small Cell Lung Cancer | Endometrial Cancer | Head And Neck Squamous Cell Carcinomas

China
Valerio Therapeutics

Recruiting

A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors

Breast Cancer | Prostate Cancer | Advanced or Metastatic Solid Tumors | Recurrent Ovarian Cancer

United States
IRCCS San Raffaele
Università Vita-Salute San Raffaele

Recruiting

Mechanisms of Somatic Mutation and Tumor Initiation in Pre-malignant Kidney Tubule Cells (SoMuKT)

Carcinoma, Renal Cell | Von Hippel-Lindau Disease

Italy
David M. Ritter

Recruiting

Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)

Tuberous Sclerosis Complex | Lymphangioleiomyomatosis

United States
University of Illinois at Urbana-Champaign
LSVT Global; Apple Inc.; Amazon.com Services LLC; Google LLC.; Microsoft Corporation and other collaborators

Recruiting

Speech Accessibility Project (SAP)

Parkinson Disease | Multiple System Atrophy | Progressive Supranuclear Palsy | Dementia With Lewy Bodies

United States
Mayo Clinic
National Institute on Aging (NIA); Minnesota HealthSolutions

Recruiting

A Study of Caregiver Connections Via Technology in Dementia

Dementia | Alzheimer Disease | Frontotemporal Dementia | Lewy Body Dementia | Parkinson Disease Dementia | Caregiver Stress

United States
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

A Study of Hansoh (HS)-10502 in Patients With Advanced Solid Tumors

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Prostatic Cancer

China
Adaptimmune

Recruiting

SPEARHEAD-3 Pediatric Study

Osteosarcoma | Neuroblastoma | Synovial Sarcoma | Malignant Peripheral Nerve Sheath Tumor (MPNST)

United States
Inion Oy

Recruiting

Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation

Fractures, Bone | Foot Deformities | Ankle Fractures | Hallux Valgus | Hallux Rigidus | Fracture of Foot | Lisfranc Fracture | Metatarsalgia | Lisfranc Injury | Deformity, Foot | Calcaneus Fracture | Talus Fracture | Medial Malleolus Fracture | Navicular Fracture | Foot Fracture | Foot Injury | Feet Deformity Tarsus | Deformity... and other conditions

Finland
University of British Columbia

Not yet recruiting

Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy (VR-PVD-RCT)

Labyrinthitis | Benign Paroxysmal Positional Vertigo | Vestibular Neuronitis | Meniere Disease | Vestibular Neuritis | Herpes Zoster Oticus | Peripheral Vestibular Disorder
Hospices Civils de Lyon

Recruiting

Control Cohort CTRL COH (CTRL COH)

Parkinson's Disease; Amyotrophic Lateral Sclerosis; Glioblastoma; Cancer Without Neurological Disease; Rheumatoid Polyarthritis

France
National Cancer Institute (NCI)

Recruiting

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Neurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome

United States
Terry L. Wahls

Recruiting

Autoimmune Intervention Mastery Course Study (AIM)

Multiple Sclerosis | Clinically Isolated Syndrome | Fibromyalgia | Post Acute Sequelae of COVID-19

United States
National Cancer Institute (NCI)

Recruiting

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Papillary Renal Cell Carcinoma | Hereditary Leiomyomatosis and Renal Cell Carcinoma | Sporadic Papillary Renal Cell Carcinoma

United States
Paul Szabolcs

Recruiting

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC (PRO-RIC)

Congenital Bone Marrow Failure Syndromes | Inflammatory Conditions | Primary Immunodeficiency (PID) | Inherited Metabolic Disorders (IMD) | Hereditary Anemias

United States
Azienda Ospedaliera, Ospedale Civile di Legnano
Acelity

Not yet recruiting

CiNPT for Abdominoplasties in Post-bariatric Patients Study (CAPS)

Obesity | Obesity, Morbid | Surgery--Complications | Surgical Wound Infection | Surgical Site Infection | Wound Infection | Scar | Wound Heal | Obesity, Abdominal | Wound | Wound Contamination | Wound Complication | Scarring | Wound Dehiscence | Incision | Wound; Abdomen | Incision Site Rash | Incision Site Bleeding | Incision Site... and other conditions
Inhibrx, Inc.

Recruiting

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

Sarcoma | Pancreatic Adenocarcinoma | Ewing Sarcoma | Gastric Adenocarcinoma | Chondrosarcoma | Solid Tumors | Malignant Pleural Mesothelioma | Colorectal Adenocarcinoma | GIST | SDH-deficient Solid Tumors

United States
Neuromed IRCCS
IRCCS Multimedica

Recruiting

Biomarkers of Synaptic Damage in Multiple Sclerosis

Multiple Sclerosis | Parkinson Disease | Amyotrophic Lateral Sclerosis | Alzheimer Disease

Italy
National Eye Institute (NEI)

Recruiting

National Eye Institute Biorepository for Retinal Diseases

Age-Related Macular Degeneration | Diabetic Retinopathy | Retinal Vein Occlusion | Retinal Disease | Von Hippel-Lindau Syndrome

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Terminated

A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I Neurofibromatosis

Neurofibromatosis and Malignant Peripheral Nerve Sheath Tumors

China
Hoffmann-La Roche

Active, not recruiting

A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors

Metastatic Melanoma | Non-small Cell Lung Cancer (NSCLC) | Solid Tumors | Esophageal Squamous Cell Carcinoma (ESCC) | Small Cell Lung Cancer (SCLC)

United States, Korea, Republic of, Denmark, France, Spain, New Zealand
NextCure, Inc.

Completed

A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors

Melanoma | Breast Cancer | Lung Cancer | Cholangiocarcinoma | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Advanced or Metastatic Solid Tumors | CRC

United States
National Cancer Institute (NCI)

Completed

flt3L With or Without Vaccine Therapy in Treating Patients With Metastatic Melanoma or Renal Cell Cancer

Recurrent Melanoma | Stage IV Melanoma | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb

Completed

Dasatinib as Therapy for Myeloproliferative Disorders (MPDs)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Polycythemia Vera | Myelofibrosis | Leukemia, Myelomonocytic, Chronic | Hypereosinophilic Syndrome | Mastocytosis | Agnogenic Myeloid Metaplasia

United States
Forma Therapeutics, Inc.

Completed

A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Cohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme) | Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas) | Cohort 3a and 3b: Chondrosarcoma | Cohort 4a and 4b: Intrahepatic... and other conditions

United States, Korea, Republic of, Australia, United Kingdom, Spain, France
Massachusetts General Hospital

Suspended

A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome

Carpal Tunnel Syndrome | Trapeziometacarpal Arthrosis | Trigger Finger | Distal Radius Fractures | Cubital Tunnel Syndrome

United States
Qlaris Bio, Inc.

Completed

A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101

Ocular Hypertension | Glaucoma | Glaucoma Congenital | Sturge-Weber Syndrome (SWS)

United States

Clinical Trials on Skin Wrinkling

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CROs in Zimbabwe

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