Clinical Trials on Sklerodermi, systemisk

Total 5014 results

Hospital for Special Surgery, New York
Roche Pharma AG; Genentech, Inc.

Terminated

Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis (RENTGPA)

Granulomatosis With Polyangiitis (Wegener's Granulomatosis)

United States
University Hospital, Montpellier

Completed

Adaptation of Alveolar-capillary Diffusion at Effort of Subjects Suffering From Complex Congenital Heart Disease (CAR-DIFF)

Pulmonary Failure | Systemic Right Ventricle | Complex Congenital Heart Disease | Single Ventricle With Fontan Circulation or Bicavo-bipulmonary Bypass

France
Medical University of Vienna

Completed

Comparison of a TauroLock™ Based Regimen to 4% Citrate as Lock Solution in Tunneled Haemodialysis Catheters for the Prevention of Bacteraemia and Dysfunction

End-stage Renal Disease | Catheter Infections

Austria
University of Florida

Withdrawn

Long Term Impact of Pediatric Acute Renal Injury in Severe Sepsis (IMPRESS)

Hypertension | Chronic Kidney Disease | Acute Kidney Injury
Soroka University Medical Center

Unknown

Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery

Post Cardiac Surgery Systemic Inflammatory Response
University of Manitoba

Completed

Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study)

Delirium | Septic Shock | Renal Failure

Canada
Hospital Universitario La Paz

Unknown

Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO (PreloaDren)

Sepsis | Systemic Inflammatory Response Syndrome | Shock | Dilated Cardiomyopathy | Low Cardiac Output

Spain
National Institute of Allergy and Infectious Diseases...

Completed

Treatment of Wegener's Granulomatosis With Cyclophosphamide

Vasculitis | Wegener's Granulomatosis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Analysis of Bronchial Tissue and Fluid in Patients With Wegener's Granulomatosis

Inflammation | Vasculitis | Wegener's Granulomatosis

United States
University of Cape Town

Completed

Health System Dynamic & Resource Requirement in a South African COVID-19 Field Hospital

COVID-19 Pandemic | Low-Income Population | Global Health | Health Resources | Field Hospitals | Health Systems

South Africa
Novartis Pharmaceuticals

Not yet recruiting

Iptacopan in Patients With ANCA Associated Vasculitis

Anti-Neutrophil Cytoplasm Antibodies (ANCA) Associated Vasculitis
Fudan University
Shanghai Zhongshan Hospital; Huashan Hospital; Children's Hospital of Fudan University and other collaborators

Recruiting

Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science

Quality Improvement | Central Venous Catheter Associated Bloodstream Infection | CLABSI - Central Line Associated Bloodstream Infection | Central Venous Catheter Related Bloodstream Infection | Central Line Infection | CRBSI - Catheter Related Bloodstream Infection | Evidence-based Nursing Practice

China
International Centre for Diarrhoeal Disease Research...

Not yet recruiting

Cytokine Storm Among Bangladeshi Patients With COVID-19

Cytokine Storm, COVID-19

Bangladesh
Chinese University of Hong Kong

Active, not recruiting

Fibroscan Study in HCC

Confirmed Diagnosis of Hepatocellular Carcinoma | Patients Who Are Scheduled to Undergo Transarterial Chemobolization, Systemic Therapy Surgery | Child's A to C Cirrhosis

Hong Kong
National University Health System, Singapore
National Medical Research Council (NMRC), Singapore; Nattopharma ASA

Completed

Treatment to Reduce Vascular Calcification in Hemodialysis Patients Using Vitamin K (TReVasc-HDK)

Vascular Calcification | Complication of Hemodialysis | Deficiency of Vitamin K2 | Systemic and Arterial Stiffness

Singapore
Incyte Corporation

No longer available

Expanded Access Program of Ruxolitinib for the Emergency Treatment of Cytokine Storm From COVID-19 Infection

COVID-19
Novartis Pharmaceuticals
Incyte Corporation

Completed

Study to Assess the Efficacy and Safety of Ruxolitinib in Patients With COVID-19 Associated Cytokine Storm (RUXCOVID)

Cytokine Storm (Covid-19)

United States, Colombia, Turkey, Spain, United Kingdom, Germany, Peru, Russian Federation, Brazil, France, Mexico, Argentina
Sohag University

Unknown

Prognostic Factors for Treatment Responses in Patients With Active Lupus Nephritis at Sohag University Hospital

We Aim to Examine the Predictors of Sustained Complete Renal Remission in Patients With Lupus Nephritis at Sohag University Hospital

Egypt
UNICEF
Pak Emirates Military Hospital Rawalpindi

Completed

Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan

Critical Illness | Covid19 | ARDS | Cytokine Release Syndrome

Pakistan
SCARE (Study group for carbapenem resistance)

Unknown

Comparison of Bloodstream Infections With Carbapenem Hetero-resistant vs Carbapenem Resistant Klebsiella Pneumoniae (COMBAT)

Bloodstream Infection

Turkey
KU Leuven
Queen's University, Kingston, Ontario

Completed

Effects of Inspiratory Muscle Training on Dyspnea Perception During Exercise in Patients With COPD (IMTCOCOPD)

COPD | Severe Systemic Illness-induced Respiratory Muscle Wasting

Canada
Aga Khan University

Unknown

Lactulose for the Prevention of Hepatic Encephalopathy in Cirrhotic Patients With Upper Gastrointestinal Hemorrhage

Encephalopathy, Hepatic | Hepatocerebral Encephalopathy | Portal-Systemic Encephalopathy | Encephalopathy, Hepatocerebral

Pakistan
Xiangcheng Zhang

Recruiting

We Collected Blood Samples From Septic Shock Patients and Measured ELABELA, Creatinine, and NGAL Levels. Survival After 7 Days Was Recorded and Analyzed to Evaluate the Potential of Serum ELABELA as an Early Diagnostic Marker for Sepsis-associated Acute Kidney Injury. (ELABELA（ELA）)

Sepsis | Septic Shock | Acute Kidney Injury

China
University College Dublin
Wellcome Trust; Health Research Board, Ireland; National Maternity Hospital,... and other collaborators

Recruiting

Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants (PARENT)

Late-Onset Neonatal Sepsis | Necrotising Enterocolitis | Culture Negative Neonatal Sepsis

Ireland
Centre Hospitalier Universitaire de Nīmes

Recruiting

L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury (CarniSave)

Shock, Septic | Acute Kidney Injury | Severe Sepsis

France
Vastra Gotaland Region
Göteborg University

Terminated

Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease (PULMORA)

Rheumatoid Arthritis | ILD | Interstitial Lung Disease Due to Systemic Disease (Disorder) | RA

Sweden
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); National Institute of Arthritis... and other collaborators

Active, not recruiting

The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach (TAPIR)

Granulomatosis With Polyangiitis

United States, Canada
Novo Nordisk A/S

Active, not recruiting

A Research Study of How the Medicine Ziltivekimab Works in the Body of Chinese Men and Women With Kidney Disease and Inflammation

Chronic Kidney Disease and Systemic Inflammation

China
Huahui Health

Active, not recruiting

A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level Viremia

Chronic HBV Infection

China
Hamad Medical Corporation

Completed

Anakinra in the Management of COVID-19 Infection

Pneumonia | Covid19 | Corona Virus Infection | Cytokine Release Syndrome | Viral Infection

Qatar
Ospedale Policlinico San Martino

Unknown

Eucaloric Ketogenic Diet in COVID-19 Cytokine Storm Syndrome (ketocovidiet)

Covid19 | Ketogenic Dieting

Italy
New Discovery LLC
Gilead Sciences

Completed

Tenofovir in Late Pregnancy to Prevent Vertical Transmission of Hepatitis B Virus

Viremia | Hepatitis B Infection | Chronic Infection

China
Johns Hopkins University

Completed

Effect of Supplementation of Fluoride on Maternal Periodontal Health, Preterm Delivery, and Perinatal Well-Being

Preterm Birth | Bacteremia | Preterm Labor | Preterm Premature Rupture of Fetal Membranes

United States
University of Washington
National Cancer Institute (NCI)

Withdrawn

Ceritinib With Brentuximab Vedotin in Treating Patients With ALK-Positive Anaplastic Large Cell Lymphoma

Anaplastic Large Cell Lymphoma, ALK-Positive | CD30-Positive Neoplastic Cells Present | Systemic Anaplastic Large Cell Lymphoma

United States
Centre Hospitalier Universitaire Dijon

Terminated

I.D.E.A.L.-I.C.U. (Initiation of Dialysis EArly Versus deLayed in Intensive Care Unit) (IDEAL-ICU)

Septic Shock | Acute Renal Failure (as Defined by the "Failure" Stage of the RIFLE Classification)

France
Assiut University

Unknown

Effect of Early Feeding of Breast Milk

Weight Gain | Feeding Disorder Neonatal | Neonatal SEPSIS
Boston Medical Center

Completed

Melphalan, Lenalidomide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis (MRD)

Multiple Myeloma

United States
BiO2 Medical

Unknown

Angel® Catheter Post Market Registry

Deep Vein Thrombosis | Pulmonary Embolism | Catheter-related Bloodstream Infection (CRBSI) Nos | Medical Device Complication | Catheter Thrombosis

United Kingdom, Germany, Italy
Assistance Publique - Hôpitaux de Paris

Unknown

Comparison Between Corticosteroid and Topical Steroids in the DRESS (DRESSCODE)

Drug Rash With Eosinophilia and Systemic Symptoms

France
Southwest Oncology Group
National Cancer Institute (NCI); Cancer and Leukemia Group B

Completed

S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis

Multiple Myeloma

United States
University of KwaZulu
Bristol-Myers Squibb

Completed

Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women

Puerperal Sepsis

South Africa
Anderson Clinical Research
Hoechst Marion Roussel

Completed

Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia.

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Canada
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
Assiut University

Not yet recruiting

The Role of NK Cells to Detect Blood Infection in ALL.

Acute Lymphoblastic Leukemia | Bloodstream Infection
Tanta University

Recruiting

Renal Resistive Index as a Predictor of Acute Kidney Injury and Evaluation of Fluid Administration in Sepsis

Sepsis | Acute Kidney Injury | Renal Resistive Index

Egypt
Medical University of Warsaw
Human Biome Institute, Poland

Not yet recruiting

The Impact of Fecal Microbiota Transplantation as an Immunomodulation on the Risk Reduction of COVID-19 Disease Progression With Escalating Cytokine Storm and Inflammatory Parameters (FeMToCOVID)

Covid19
National Institute of Nursing Research (NINR)

Recruiting

Patient-Centered Assessment of Symptoms and Outcomes

Cancer | Fatigue | Lupus | CFS | ME/CFS | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | Systemic Lupus Erthematosus | Sjogrens

United States
National Institute of Arthritis and Musculoskeletal...

Recruiting

Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions

Arthritis | Still's Disease, Adult-Onset | Systemic Inflammation | Autoinflammatory Syndrome

United States
Peking Union Medical College Hospital

Completed

Anti-neutrophil Cytoplasmic Antibody in Interstitial Lung Disease.

Interstitial Lung Disease | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

China

Clinical Trials on Sklerodermi, systemisk

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