Clinical Trials on Spherocytosis, Hereditary

Total 2644 results

Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Multicenter Analysis of Genomic and Metabolic Data of Neonatal Genetic Diseases (MAOFGAMDNGD)

Hereditary Diseases

China
Hospices Civils de Lyon

Completed

Subsequent Bevacizumab Treatment in Patients With HHT. Follow up BABH (BEST)

HHT | Hemorrhagic Hereditary Telangiectasia

France
University Medicine Greifswald

Completed

EUROPAC-2 - Pain Treatment of Hereditary and Idiopathic Pancreatitis

Pancreatitis
National Human Genome Research Institute (NHGRI)

Completed

Study of Clinical and Molecular Manifestations of Genetic Disorders

Hereditary Diseases

United States
University Hospital, Essen

Recruiting

Evaluation of Video-assisted Instructions of Nasal Self-packing in Patients With HHT

Hereditary Haemorrhagic Telangiectasia

Germany
Mayo Clinic

Active, not recruiting

Ultra-low-dose Chest CT for HHT

Hereditary Hemorrhagic Telangiectasia

United States
Nanoscope Therapeutics Inc.

Enrolling by invitation

Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study (REMAIN)

Eye Diseases | Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies

United States, Puerto Rico
Kaiser Permanente
Dana-Farber Cancer Institute; Columbia University; Emory University; University... and other collaborators

Active, not recruiting

Cancer Health Assessments Reaching Many (CHARM)

Hereditary Cancer Syndrome

United States
IRCCS Fondazione Stella Maris

Completed

Trehalose Administration in Subjects With Spastic Paraplegia 11 (3AL-SPG11) (3AL-SPG11)

Hereditary Spastic Paraplegia | Spastic Paraplegia Type 11

Italy
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Educational CD-ROM Compared With Standard Informed Consent for Patients With Colorectal Cancer or a Family History of Colorectal Cancer

Colorectal Cancer | Hereditary Non-polyposis Colon Cancer

United States
Nanoscope Therapeutics Inc.

Completed

Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE] (RESTORE)

Eye Diseases | Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies

United States, Puerto Rico
Centre Hospitalier Universitaire Dijon

Completed

Prospective Descriptive Study of the Angiogenic T Cell Population in Subjects With Hereditary Hemorrhagic Telangiectasia (HHT) (TangRO)

Hereditary Hemorrhagic Telangiectasia

France
Xuanwu Hospital, Beijing

Recruiting

Spinal Cord Stimulation Therapy for Hereditary Spastic Paraplegias Patients

Gait | Motor Function

China
NYU Langone Health

Recruiting

The Natural History of Familial Dysautonomia

Hereditary Sensory and Autonomic Neuropathies | Familial Dysautonomia (Riley-Day Syndrome) | Hereditary Sensory and Autonomic Neuropathy 3

United States, Israel
Istituti Clinici Scientifici Maugeri SpA

Completed

Social Evaluated Cold Pressor Test in Hereditary Angioedema Patients (FROSEN)

Hereditary Angioedema

Italy
University Hospital, Grenoble

Completed

Assessment of the State of Health, Quality of Life and Expectations of Patients With Hereditary Angioedema (BESQAOH)

Hereditary Angioedema

France
Associazione Italiana per lo Studio del Pancreas
General and Pancreatic Surgery Unit, University of Verona; Fondazione Valsecchi and other collaborators

Recruiting

Familial Pancreatic Cancer PROPHilation Program in Italy (PROPH-ITA)

Candidates for Hereditary Pancreatic Cancer Testing

Italy
The Cleveland Clinic
National Eye Institute (NEI)

Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study (DISCOVER)

Retinal Diseases | Retinal Detachment | Epiretinal Membrane | Fuchs Endothelial Dystrophy | Macular Hole

United States
Valeria Sanchez-Huerta
Emmecell

Unknown

Phase 1 Study to Evaluate the Safety and Tolerability of EO1404 in the Treatment of Corneal Edema

Corneal Edema | Fuchs' Endothelial Dystrophy | Fuchs Dystrophy | Corneal Endothelial Dystrophy | Pseudophakic Bullous Keratopathy | Corneal Transplant Failure

Mexico
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families

Lynch Syndrome | Hereditary Breast Carcinoma | Hereditary Ovarian Carcinoma

United States
L.V. Prasad Eye Institute
Allergan

Recruiting

CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops

Congenital Hereditary Endothelial Dystrophy of Cornea

India
University of British Columbia

Unknown

Utility of Fibroscan in Estimating Hepatic Iron Concentration

Hereditary Anemias

Canada
Jaeb Center for Health Research
Usher 1F Collaborative; Marjorie C. Adams Foundation

Active, not recruiting

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F (RUSH1F)

Retinal Degeneration | Retinitis Pigmentosa | Eye Diseases, Hereditary

Switzerland, United States, Germany, Netherlands, Canada, France, Israel
Universitaire Ziekenhuizen KU Leuven

Withdrawn

Implications for Quality of Life and Quality of Care in Patients With Hereditary Haemochromatosis

Hereditary Haemochromatosis

Belgium
Ultragenyx Pharmaceutical Inc

Completed

Safety and Pharmacokinetics of Sialic Acid Tables in Patients With Hereditary Inclusion Body Myopathy (HIBM)

Hereditary Inclusion Body Myopathy (HIBM)

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

Ovarian Cancer | Genetic Predisposition to Disease | Breast Cancer Female | Hereditary Diseases | Gene Mutation-Related Cancer | Hereditary Breast and Ovarian Cancer | Hereditary Cancer Syndrome

United States
Hospices Civils de Lyon

Recruiting

Stress-Echography in Hereditary Haemorrhagic Telangiectasia Patient With Hepatic Involvement (ROSE)

Hereditary Hemorrhagic Telangiectasia | Rendu Osler Disease

France
University Health Network, Toronto
Women's College Hospital; Jewish General Hospital; IWK Health Centre; British Columbia... and other collaborators

Recruiting

Cell-free DNA in Hereditary And High-Risk Malignancies (CHARM)

Hereditary Cancer Syndrome

Canada
UMC Utrecht
Universitaire Ziekenhuizen KU Leuven; Maastricht University Medical Center; Carl...

Completed

The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation (ADVISE)

Vision Disorders | Fuchs Dystrophy | Bullous Keratopathy | Endothelial Corneal Dystrophy

Netherlands, Belgium
National Center for Research Resources (NCRR)
Yale University

Completed

Phase III Randomized, Placebo-Controlled, Crossover Study of Soy Protein Isolate for Hereditary Hemorrhagic Telangiectasia

Hereditary Hemorrhagic Telangiectasia
University of British Columbia
MHE Coalition

Completed

The Health-Related Quality of Life in Patients With Hereditary Multiple Exostoses

Exostoses, Multiple Hereditary

Canada
Vanderbilt University Medical Center
National Cancer Institute (NCI)

Completed

Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer

Colorectal Cancer | Precancerous Condition | Hereditary Non-polyposis Colon Cancer

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Ascorbic Acid Treatment in CMT1A Trial (AATIC) (AATIC)

Charcot-Marie-Tooth Disease | Hereditary Motor and Sensory Neuropathies

Netherlands
M.D. Anderson Cancer Center
Duncan Family Institute

Unknown

A Social Media Approach to Improve Genetic Risk Communication Phase I

Hereditary Diseases

United States
University of Pittsburgh
National Center for Research Resources (NCRR)

Completed

A Pilot Study of Use of Calcium Channel Blocker to Decrease Inflammation and Pain in Hereditary Pancreatitis

Pancreatitis

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm | Hereditary Malignant Neoplasm

United States
Ultragenyx Pharmaceutical Inc

Completed

An Open Label Phase 2 Extension Study of Higher Dose Sialic Acid-Extended Release (SA-ER) Tablets and Sialic Acid-Immediate Release (SA-IR) Capsules in Patients With Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy

GNE Myopathy | Hereditary Inclusion Body Myopathy (HIBM)

United States, Israel
National Center for Research Resources (NCRR)
University of Vermont

Completed

Study of the Natural History and Genotype-Phenotype Correlations of Hereditary Hemorrhagic Telangiectasia Patients

Hereditary Hemorrhagic Telangiectasia
CENTOGENE GmbH Rostock

Completed

Epidemiological Analysis for Hereditary Angioedema Disease (EHA)

Abdominal Pain | Functional Abdominal Pain

United Kingdom, Germany, Turkey, Poland, Italy, Japan
University of Sao Paulo General Hospital

Recruiting

Analysis of the Instestinal Microbiome of Patients With Transthyretin Amyloidosis (AMIAT)

Microbial Colonization | Amyloidosis, Hereditary, Transthyretin-Related

Brazil
University Hospital, Essen

Recruiting

Influence of Hypoxic Induced Factors in Patients With Hereditary Hemorrhagic Telangiectasia

Hereditary Hemorrhagic Telangiectasia

Germany
Charite University, Berlin, Germany
Shire International GmbH

Active, not recruiting

Lanadelumab in FXII-associated Cold Autoinflammatory Syndrome (FACAS) (LANA-FXII)

Hereditary Autoinflammatory Disease

Germany
Hospices Civils de Lyon

Completed

Evaluation of Obstetrical and Neonatal Complications in Hereditary Haemorrhagic Telangiectasia (HHT) (CONCERTO)

Hereditary Hemorrhagic Telangiectasia | Osler Rendu Disease

France
Rennes University Hospital

Completed

Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis (HEMOCOEUR)

Myocardial Iron Overload | HFE-Associated Hereditary Hemochromatosis

France
National Human Genome Research Institute (NHGRI)
National Center for Advancing Translational Sciences (NCATS); Therapeutics...

Completed

Phase I Clinical Trial of ManNAc in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)

GNE Myopathy | Hereditary Inclusion Body Myopathy (HIBM)

United States
Asociación para Evitar la Ceguera en México
Emmecell

Recruiting

Study to Assess Safety and Tolerability of Multiple Doses of EO2002

Endothelial Dysfunction | Corneal Edema | Fuchs' Endothelial Dystrophy | Fuchs Dystrophy | Corneal Endothelial Dystrophy | Bullous Keratopathy | Pseudophakic Bullous Keratopathy | Corneal Edema Pseudophakic

Mexico
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

North Carolina Newborn Exome Sequencing for Universal Screening (NC_NEXUS)

Metabolism, Inborn Errors | Hearing Loss | Hereditary Disease

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Not yet recruiting

PeLear CCC: Proyecto Latino Contra Cancer Colorectal (PeLear CCC)

Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colon Cancer | Colon Adenocarcinoma | Colon Rectal Cancer | Hereditary Nonpolyposis Colon Cancer

United States
University of California, San Diego

Completed

Submucosal Bevacizumab for the Management of Recurrent Epistaxis in Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

Hereditary Hemorrhagic Telangiectasia (HHT)

United States
University of California, San Diego

Completed

Topical Bevacizumab for the Management of Recurrent Epistaxis in Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

Hereditary Hemorrhagic Telangiectasia (HHT)

United States

Clinical Trials on Spherocytosis, Hereditary

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Malawi

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations