Clinical Trials on Spine Fusion for Degenerative Spine Disease in Canada

Total 91 results

Medtronic Spinal and Biologics

Completed

A Prospective, Multicenter Observational Study on MAST™ (Minimal Access Spinal Technologies) Fusion Procedures for the Treatment of the Degenerative Lumbar Spine (MASTERS-D)

Lumbar Spine Degeneration | Degenerative Lumbar Spine Causing Back and/or Leg Pain

Spain, Germany, Belgium, Israel, Portugal, Austria, Canada, Czechia, Greece, Italy, Netherlands, Poland, Slovakia, United Kingdom
Hamilton Health Sciences Corporation
McMaster University; DJO Incorporated; Stryker Canada LP

Recruiting

To Brace or Not to Brace for Single Level Lumbar Fusion Pilot (BRACE Pilot)

Fusion of Spine | Lumbar Spondylosis

Canada
AO Foundation, AO Spine

Completed

Predictors of Mortality and Morbidity in the Surgical Management of Primary Tumors of the Spine (PT)

Spine Tumor

Canada
University of Calgary

Not yet recruiting

Ablation and Cementoplasty for Painful Bone Lesions

Bone Metastases | Spine Metastases | Bone Lesion

Canada
Windsor-Essex Compassionate Care Community
Cairo University

Recruiting

The Effect of Intrawound Vancomycin Powder in Spine Surgery

Spine Disease

Egypt, Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Evaluation of the Nursing C-Spine (Phase IV)

Fracture of Cervical Spine | Fracture Dislocation of Cervical Spine

Canada
Centre hospitalier de l'Université de Montréal...

Withdrawn

High Dose Steroids for Dysphagia (SHDD)

Dysphagia | Cervical Spine Disease

Canada
University of Alberta

Completed

The Underlying Mechanism of Spinal Manipulative Therapy and the Effect of Pain on Physical Outcome Measures

Low Back Pain | Muscle Weakness | Spine Stiffness | Degeneration of Lumbosacral Intervertebral Disc

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Evaluation of the Safety of C-Spine Clearance by Paramedics

Fracture of Cervical Spine

Canada
Complejo Hospitalario Universitario de Granada

Unknown

Injections in the Diagnosis and Treatment of Lumbar Facet Syndrome

Facet Joint Pain | Facet Syndrome of Lumbar Spine | Facet Joints; Degeneration

Spain
StemCells, Inc.

Terminated

Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury

Cervical Spinal Cord Injury | Spine Injury | Cervical Spine Injury

United States, Canada
Unity Health Toronto

Completed

Does Pre-operative Carbohydrate Loading Reduce Insulin Resistance and Improve Outcomes in Elective Surgical Patients? (Preop)

Spine Surgery | Coronary Artery Bypass Graft Surgery

Canada
Zetagen Therapeutics, Inc

Recruiting

ZetaFuse™ Bone Graft in the Repair of Bone Defects From Metastatic Breast Cancer in the Spinal Vertebral Body (ZGMBC)

Metastatic Breast Cancer in the Spine

Canada
FUSMobile Inc.

Active, not recruiting

Safety and Initial Feasibility of Using the Neurolyser XR Device for the Treatment of Axial Chronic Low Back Pain

Facet Syndrome of Lumbar Spine

Canada
Lawson Health Research Institute

Unknown

Automatic Self Transcending Meditation (ASTM) for Patients With Severe Age Related Macular Degeneration (AMD)

Age-related Macular Degeneration | Low Vision

Canada
University of Manitoba
Health Sciences Centre Foundation, Manitoba

Recruiting

Intraspinal Pressure Monitoring for Acute Traumatic Spinal Cord Injury: A Validation Study

Spinal Cord Injuries | Spine Injury

Canada
Pediatric Spine Foundation
Columbia University

Recruiting

Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals (MCGR)

Early-Onset Scoliosis Deformity of Spine

United States, Canada, Finland, Hong Kong
University of Iowa
Orthopedic Research and Education Foundation; Pediatric Spine Study Group

Recruiting

Casting vs Bracing for Idiopathic Early-Onset Scoliosis (CVBT)

Scoliosis Idiopathic | Early-Onset Scoliosis Deformity of Spine

United States, Singapore, Hong Kong, United Kingdom, Canada, Italy, New Zealand, Turkey
Neurocrine Biosciences

Completed

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Epileptic Encephalopathy | Continuous Spike and Wave During Sleep

United States, Denmark, Spain, Switzerland, United Kingdom, Canada
The London Spine Centre
Lawson Health Research Institute; The Physicians' Services Incorporated Foundation

Completed

Surgery Versus Standardized Non-operative Care for the Treatment of Lumbar Disc Herniations: A Canadian Trial

Lumbar Radiculopathy | Lumbar Spine Disc Herniation

Canada
University Health Network, Toronto
Sunnybrook Health Sciences Centre

Recruiting

Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial)

Spinal Cord Injuries | Spine Disease

Canada
Université de Montréal
Canadian Institutes of Health Research (CIHR); Fonds de la Recherche en Santé...

Terminated

Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning? (WOTB)

Age-related Macular Degeneration | Cognitive Impairment | Dementia | Hearing Loss | Low Vision | Low Vision Aids | Reading Problem

Canada
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan, United Kingdom
Holland Bloorview Kids Rehabilitation Hospital
Laval University

Active, not recruiting

Children and Teens in Charge of Their Health (CATCH)

Cerebral Palsy | Health Behavior | Spina Bifida

Canada
McGill University
Canadian Institutes of Health Research (CIHR); McMaster University; Drexel University

Active, not recruiting

The Impact of Participation on Body Functions Among Youth With Physical Disabilities

Cerebral Palsy | Spina Bifida | Musculoskeletal Disorders

Canada
Novartis

Completed

A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study (RESTORE)

Diabetic Macular Edema

Greece, Belgium, Spain, France, Netherlands, Australia, Canada, Germany, Hungary, Italy, Switzerland, Turkey, United Kingdom
Western University, Canada

Recruiting

Evaluation of the Transitional and Lifelong Care Program

Cerebral Palsy | Developmental Disability | Spina Bifida

Canada
University of British Columbia
Bionic Power

Active, not recruiting

The Effects of a Powered Knee Orthosis on Gait Kinematics of Children With Knee Extension Deficiency

Cerebral Palsy | Spinal Cord Injuries | Spina Bifida

Canada
University of Alberta

Completed

Comparing Urinary Tract Infections in Children With Spina Bifida Using Two Types of Catheters for Catheterization

Neurogenic Bladder | Spina Bifida

Canada
McGill University
Canadian Institutes of Health Research (CIHR); McGill University Health Centre... and other collaborators

Completed

The Effectiveness of Participation-focused Interventions on Body Functions of Youth With Physical Disabilities

Cerebral Palsy | Muscular Dystrophies | Spina Bifida | Musculoskeletal Disorder

Canada
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab (Intravitreal Injections) Versus Laser Treatment in Patients With Visual Impairment Due to Diabetic Macular Edema (RED-ES)

Diabetic Macular Edema | Visual Impairment

Spain
University of Calgary

Recruiting

Robotic Walking for Children Who Cannot Walk (RoWaCaWa)

Cerebral Palsy | Brain Injuries | Spinal Cord Injuries | Mobility Limitation | Spina Bifida

Canada
Middle East Technical University

Completed

Serum Cartilage Oligomeric Matrix Protein Levels After 12 Weeks of Different Exercises

Osteoarthritis | Degenerative Lesion of Articular Cartilage of Knee | Articular Cartilage Disorder of Knee

Turkey
University Health Network, Toronto
Sunnybrook Health Sciences Centre

Recruiting

Sleep Apnea in Paralympic Ontario-Resident aThletes With Spinal Cord Injury (SPORTS) Study

Sleep Disorder | Sleep Apnea | Spinal Cord Injuries | Spine Disease | Breathing Disorder During Sleeping

Canada
McGill University

Not yet recruiting

Examining Capacity Building of Youth With Physical Disabilities to Pursue Participation Following the PREP Intervention.

Cerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile Arthritis

Canada
McGill University
Canadian Institutes of Health Research (CIHR); McMaster University; Drexel University

Not yet recruiting

Downstream Effects of Personalized 'Top-down' Participation-based Interventions Among Youth With Physical Disabilities

Cerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile Arthritis

Canada
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
TOPMED
Natural Sciences and Engineering Research Council, Canada; Orthèse Hallux Valgus...

Completed

Dimensional Validation of the Hallux Valgus Orthosis

Hallux Valgus

Canada
Dr. Stephen Perry

Completed

Hallux Valgus and Custom Orthotic Prescription

Hallux Valgus

Canada
Nova Scotia Health Authority
Arthrex, Inc.

Completed

Prospective, Multi-Center Clinical Evaluation of the Open Wedge Osteotomy and Low Profile Plate & Screw (LPS) System Compared to the Proximal Chevron Osteotomy for the Treatment of Hallux Valgus With an Increased Intermetatarsal Angle (Hallux valgus)

Hallux Valgus

Canada
Holland Bloorview Kids Rehabilitation Hospital
The Hospital for Sick Children; University of Toronto; University of Ottawa; Social... and other collaborators

Completed

A Peer E-mentoring Intervention to Improve Employment

Cerebral Palsy | Muscular Dystrophy | Physical Disability | Spinal Cord Injury | Spina Bifida | Juvenile Arthritis

Canada
Universidad de Granada

Completed

Effectiveness of a Cognitive-behavioral Program of Coping With Psychological Stress in People With Retinitis Pigmentosa (RCT)

Stress, Psychological | Vision Disorders | Self Efficacy | Psychopathy

Spain
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Two "Treat and Extend" Treatment Algorithms Versus Ranibizumab As Needed in Patients With Macular Edema and Visual Impairment Secondary to Diabetes Mellitus (RETAIN)

Diabetic Macular Edema

Belgium, United Kingdom, Netherlands, Ireland, Switzerland, Italy, Hungary, France, Spain, Portugal, Poland, Czech Republic, Greece
QLT Inc.

Completed

Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01)

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

Canada, United States, Germany, Netherlands, United Kingdom
Novartis Pharmaceuticals

Completed

Ranibizumab Intravitreal Injections in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRYSTAL)

Central Retinal Vein Occlusion | Macular Edema

Greece, Hungary, Turkey, Australia, Austria, Netherlands, United Kingdom, Italy, Spain, Ireland, Portugal, Slovakia, Canada, Switzerland, Czech Republic, Poland, Denmark, Sweden
Novartis Pharmaceuticals

Terminated

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion (RAPTOR)

Branch Retinal Vein Occlusion

China, Austria, Czechia, Russian Federation, Taiwan, United Kingdom, Canada, Japan, United States, France, Israel, Germany, Italy, Hong Kong, Spain, Denmark, Slovakia, Puerto Rico, Switzerland
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia

Pathological Myopia

Germany, India, Japan, Turkey, Austria, Switzerland, Italy, Lithuania, Hungary, France, Slovakia, United Kingdom, Korea, Republic of, Portugal, Hong Kong, Canada, Singapore, Spain, Latvia, Poland
Novartis Pharmaceuticals

Terminated

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion (RAVEN)

Central Retinal Vein Occlusion

China, Czechia, Germany, Russian Federation, Turkey, United States, Australia, Canada, Spain, United Kingdom, Thailand, Israel, Netherlands, Italy, Hungary, France, Greece, Puerto Rico, Malaysia, Japan
QLT Inc.

Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

United States, Canada, Germany, Netherlands, United Kingdom
QLT Inc.

Completed

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Leber Congenital Amaurosis (LCA) | Retinitis Pigmentosa (RP)

United States, Canada, Denmark, Germany, Netherlands, Switzerland, United Kingdom

Clinical Trials on Spine Fusion for Degenerative Spine Disease in Canada

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