Clinical Trials on Substance Use Disorder (SUD)

Total 9079 results

ARCAGY/ GINECO GROUP

Completed

Use of FACT-GOG/NTX Questionnaire in Peripheral Neurotoxicity & Validation of a French Version of This Questionnaire

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

France
Seoul National University Hospital
Ministry of Food and Drug Safety, Korea

Unknown

HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction

Kidney Failure, Chronic | Stevens-Johnson Syndrome

Korea, Republic of
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect) (SUPER)

Heart Failure | Renal Cell Carcinoma | Hypertension | Cardiotoxicity

Canada
Helse Stavanger HF
University Hospital, Akershus

Unknown

Challenge Test for Acetylsalicylic Acid Hypersensitivity

Asthma, Aspirin-Induced | ASA Intolerant Asthma | Asthma Aspirin-sensitive | Asthma, Nasal Polyps, and Aspirin Intolerance

Norway
Cairo University
Misr International University

Completed

Comparison of Weekly Versus Every Three Weeks of Carboplatin Plus Paclitaxel in Patients With Advanced Epithelial Ovarian Cancer

Advanced Epithelial Ovarian Cancer

Egypt
Lowell Anthony, MD
Entrinsic Bioscience Inc.

Completed

Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs

Diarrhea | Neuroendocrine Tumors | Carcinoid Syndrome | Carcinoid Tumor of GI System

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia

Untreated Childhood Acute Lymphoblastic Leukemia | Childhood T Acute Lymphoblastic Leukemia | Neurotoxicity Syndrome | Childhood B Acute Lymphoblastic Leukemia | Cognitive Side Effects of Cancer Therapy | Psychological Impact of Cancer | Long-Term Effects Secondary to Cancer Therapy in Children

United States, Canada, Australia, New Zealand
University of Edinburgh
NHS Lothian

Completed

Study to Compare Cardiovascular Side Effects of Teysuno Versus Capecitabine (TOFFEE)

Pancreatic Cancer | Gastrointestinal Cancer | Bile Duct Neoplasms | Cancer of Unknown Primary Site

United Kingdom
National Cancer Institute (NCI)

Completed

Bevacizumab and PEG-Interferon Alfa-2b in Treating Patients With Metastatic or Unresectable Carcinoid Tumors

Metastatic Gastrointestinal Carcinoid Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Regional Gastrointestinal Carcinoid Tumor

United States
Sun Yat-sen University

Recruiting

Evaluation of Impedance Cardiography for Assessing Hemodynamic Shifts in Patients With LA-NSCLC During Treatment.

Non-small Cell Lung Cancer | Cardiac Toxicity

China
Military Institute of Medicine, Poland

Recruiting

Radiation-induced Cardiac Toxicity After Non-small Cell Lung Cancer Radiotherapy

Non-small Cell Lung Cancer | Radiation Toxicity | Cardiac Toxicity

Poland
James Chodosh, MD, MPH
Massachusetts Eye and Ear Infirmary; Fonds de recherche en ophtalmologie de...

Withdrawn

Topical Infliximab in Autoimmune Eyes With Keratoprosthesis

Stevens-Johnson Syndrome | Mucous Membrane Pemphigoid | Toxic Epidermal Necrolysis (Lyell) Syndrome

United States, Canada
Genelex Corporation
University of Utah

Completed

YouScript IMPACT Registry (IMPACT)

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme Deficiency | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome... and other conditions

United States
AIO-Studien-gGmbH

No longer available

A Randomized, Open-label Phase III Trial of Mapisal® Versus an Urea Hand-foot Cream as Prophylaxis for Capecitabine-induced Hand-foot Syndrome in Patients With Gastrointestinal Tumors or Breast Cancer (PROCAPP)

the Treatment Hand-foot Syndrome Patients With Gastrointestinal Tumors or Breast Cancer, Who Are Treated With Capecitabine

Germany
University of Virginia

Recruiting

Exercise Preconditioning in Ovarian Cancer

Ovarian Cancer

United States
Aarhus University Hospital
Rigshospitalet, Denmark; Herlev Hospital

Recruiting

TDM for Optimized Outcome in Patients With mRCC.

Kidney Cancer | Renal Cell Carcinoma Metastatic | Drug Toxicity | Drug Side Effect | Drug Mechanism

Denmark
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Withdrawn

BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

Breast Cancer | Brain and Central Nervous System Tumors | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Drug/Agent Toxicity by Tissue/Organ
Willows Health
Nottingham Trent University

Not yet recruiting

Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) (BRANCH-P)

Depression | Heart Diseases | Cardiovascular Diseases | HIV Infections | Obesity | Diabetes | Cancer | Chronic Kidney Diseases | Arthritis | Bulimia | Alzheimer Disease | Cellulitis | Cirrhosis | Eczema | Osteoporosis | Appendicitis | Bronchitis | Bowel Disease | Gout | Alcoholic Liver Disease | Flu | High Cholesterol | Allergies | Indigestion | ... and other conditions

United Kingdom
Massachusetts General Hospital
M.D. Anderson Cancer Center; National Cancer Institute (NCI)

Active, not recruiting

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma

Brain Tumor | Medulloblastoma | Pineoblastoma

United States
Rijnstate Hospital

Terminated

N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy (NAC-PNP)

Carcinoma, Non-Small-Cell Lung | Mesothelioma | Carcinoma, Small Cell Lung

Netherlands
University of Nebraska

Completed

Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery (Chemobrain)

Acute Myeloid Leukemia | Multiple Myeloma | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Mild Cognitive Impairment | Myelodysplastic Syndrome | Acute Lymphoid Leukemia | Effects of Chemotherapy | Non-hodgkin Lymphoma

United States
Silesian Centre for Heart Diseases
Medical Research Agency, Poland

Not yet recruiting

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Heart Failure | Breast Cancer | Breast Diseases | Cardiotoxicity | Molecular Mechanisms of Pharmacological Action | Angiotensin Receptor Antagonists | Neoplasm, Breast | Cardiac Toxicity | Angiotensin II Type 1 Receptor Blockers | Cancer, Therapy-Related | Antihypertensive Agents | Sacubitril/Valsartan | Cancer...

Poland
Ciusss de L'Est de l'Île de Montréal
Covid-19 Early Treatment Fund

Not yet recruiting

Cyproheptadine in Severe COVID-19 : A Unblinded Randomized Trial

Serotonin Syndrome | Platelet Dysfunction | Viral Pneumonia
Genelex Corporation
Harding University

Completed

Pharmacogenetic Testing Among Home Health Patients

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme... and other conditions

United States
Beni-Suef University

Completed

PRF in Management of Chronic Multiple Oral Ulcers

Oral Ulcer Due to Pemphius Vularis | Oral Ulcer Due to Benign Mucous Membrane Pemphioid | Oral Ulcer Due to Steven Johnson's Syndrome

Egypt
Istanbul University

Completed

Cardiac Management of Patients With Thalassemia Minor and Breast Cancer (AQUA)

Heart Diseases | Breast Cancer | Thalassemia Minor

Turkey
Prof. Dr. Fridoon Jawad Ahmad
University of Lahore; Bahria International Hospital

Unknown

To Determine the Efficacy of Neurokinin 1 Receptor Antagonist as a Therapeutic Tool Against Cytokine Storm and Respiratory Failure in Covid-19 Patients

Neurokinin 1 Receptor, Substance P, Respiratory Illness, Inflammation, Covid-19, Coronavirus

Pakistan
Chulalongkorn University

Completed

Vitamin D Levels in Non-immediate Drug Hypersensitivity Case-control Study

Vitamin D Deficiency | Stevens-Johnson Syndrome | Maculopapular Exanthem | Drug Reaction With Eosinophilia and Systemic Symptom | Drug-Induced Rash

Thailand
Apurano Pharmaceuticals GmbH

Recruiting

Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis

Stroke | Pain | Multiple Sclerosis | Chronic Pain | Traumatic Brain Injury | Neuropathic Pain | Pain, Chronic | Chronic Pain Syndrome | Paraplegia | Phantom Pain | Pain Syndrome | Central Neuropathic Pain | Phantom Limb Syndrome With Pain

Germany
Chulalongkorn University

Completed

Characteristics of Patients Diagnosed With NSAID Sensitivity in Thailand

Aspirin Sensitivity | Aspirin-exacerbated Respiratory Disease | NSAID-Induced Anaphylactoid Reaction | Aspirin-Induced Angioedema-Urticaria | Aspirin Allergy | NSAID-Induced Asthma | NSAID-Induced Angioedema-Urticaria | Aspirin-Induced Anaphylactoid Reaction

Thailand
Augusta University

Completed

Contribution of Dolutegravir to Obesity and Cardiovascular Disease

Vascular Diseases | Body Weight Changes | Cardiovascular Abnormalities | HIV-1-infection | Body Fat Disorder | HIV-Associated Lipodystrophy Syndrome | Antiviral Drug Adverse Reaction | Abnormality of Adipose Tissue

United States
Massachusetts General Hospital
Dana-Farber Cancer Institute

Recruiting

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

Melanoma Stage IV | Melanoma Stage III | Drug Toxicity | Immune-related Adverse Event | Skin Cancer Stage III | Skin Cancer Stage IV | Drug-Induced Colitis

United States
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy (RICT-LUNG)

Non-small Cell Lung Cancer | Radiation Toxicity

Canada
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer

Sarcoma | Cervical Cancer | Ovarian Cancer | Fallopian Tube Cancer | Endometrial Cancer | Neurotoxicity | Primary Peritoneal Cavity Cancer

United States
Assiut University

Completed

Ultrasound Guided Corticosteroid Injection at A1 Pulley in Comparison to Percutaneous A1 Pulley Release as a Treatment for Idiopathic Trigger Finger

US-guided Release of the A1 Pulley Responsible for Trigger Finger is Feasible With a 21-gauge Needle

Egypt
CytoSorbents, Inc

Recruiting

CytOSorb TreatMent Of Critically Ill PatientS Registry (COSMOS)

Sepsis | Burns | Septic Shock | Trauma | Infectious Disease | Pancreatitis | Acute Respiratory Distress Syndrome | Liver Transplant; Complications | Drug Overdose | Acute Liver Failure | Cardiogenic Shock | Rhabdomyolysis | Acute on Chronic Liver Failure | Hemophagocytic Lymphohistiocytoses | Extracorporeal Life Support and other conditions

Spain, Italy, Germany, Portugal
Scripps Health

Completed

Amifostine Followed by High Dose Chemotherapy in Treating Patients With Hematologic Cancer or Solid Tumors

Lymphoma | Breast Cancer | Ovarian Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Drug/Agent Toxicity by Tissue/Organ

United States
Epic Research & Diagnostics, Inc.

Completed

Prognostic Indicators as Provided by the EPIC ClearView (GBMC)

Coronary Artery Disease | Pneumonia | Hypertension | Diabetes | Irritable Bowel Syndrome | Atrial Fibrillation | Asthma | Renal Failure | Emphysema | Cholecystitis | Cirrhosis | Crohn's Disease | Ulcerative Colitis | Acute Renal Failure | Diverticulitis | Pancreatitis | Bronchitis | Valvular Heart Disease | Inflammatory Bowel Disease and other conditions

United States
Apurano Pharmaceuticals GmbH

Recruiting

Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis

Stroke | Pain | Multiple Sclerosis | Chronic Pain | Traumatic Brain Injury | Neuropathic Pain | Pain, Chronic | Chronic Pain Syndrome | Paraplegia | Phantom Pain | Pain Syndrome | Central Neuropathic Pain | Phantom Limb Syndrome With Pain

Germany
University of Edinburgh

Recruiting

Fibrosis in Chronic and Delayed Myocardial Infarction (FCDMI)

Aortic Stenosis | Carcinoid Syndrome | Chemotherapy Induced Systolic Dysfunction

United Kingdom
Ain Shams University
Misr International University

Recruiting

Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Cisplatin Among Egyptian Non-small Cell Lung Cancer Patients

Non Small Cell Lung Cancer | Cardiotoxicity | Nephropathy

Egypt
Ciusss de L'Est de l'Île de Montréal

Not yet recruiting

Pilot Study for Cyproheptadine in Hospitalized Patient for COVID-19

COVID-19 Pneumonia | Serotonin Syndrome | Platelet Dysfunction | Viral Pneumonia
University of Southern Denmark
Odense University Hospital

Completed

Implementation and Quality Assurance of DPYD-genotyping in Patients Treated With Fluoropyrimidines.

Breast Cancer | Gastric Cancer | Rectal Cancer | Bile Duct Cancer | Colon Cancer | Pancreas Cancer | Oesophageal Cancer | Adverse Drug Event

Denmark
Medical University of Warsaw

Recruiting

Possible Differences in HCC Course Depending on DAA Treatment

Liver Cirrhosis | Carcinoma, Hepatocellular | Hepatitis C, Chronic | Drug Effect | Hepatitis C Virus Infection, Response to Therapy of | Drug Side Effect

Poland
Kartal Kosuyolu Yuksek Ihtisas Education and Research...
Trakya University

Completed

The Use of Midazolam and Remifentanil During Dialysis Access Procedures

Chronic Kidney Diseases | Patient Satisfaction | Arteriovenous Fistula | Adverse Reaction to Drug | Analgesic Adverse Reaction | Sedative Adverse Reaction | Midazolam Adverse Reaction
Gynecologic Oncology Group
National Cancer Institute (NCI); Canadian Cancer Trials Group

Completed

Radiation Therapy and Cisplatin With or Without Epoetin Alfa in Treating Patients With Cervical Cancer and Anemia

Anemia | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Radiation Toxicity | Cervical Squamous Cell Carcinoma | Drug Toxicity | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage IVA Cervical Cancer

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
Seoul National University Hospital
Ministry of Health & Welfare, Korea

Available

Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation

Limbal Stem Cell Deficiency | Ocular Cicatricial Pemphigoid | Stevens-johnson Syndrome | Chemical Burn

Korea, Republic of
Mayo Clinic

Enrolling by invitation

Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

Autoimmune Diseases | Diabetes | Chronic Kidney Diseases | Tobacco Use | Overweight or Obesity | Inflammatory Disease | MRSA | Infections Joint Prosthetic | MSSA Colonization

United States
National Cancer Institute (NCI)

Completed

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

Ependymoma | Medulloblastoma | PNET | Diffuse Intrinsic Pontine Glioma | Germinoma

United States

Clinical Trials on Substance Use Disorder (SUD)

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