Clinical Trials on Surgically-Induced Liver Failure in New Zealand

Total 220 results

Vital Therapies, Inc.

Terminated

Safety and Efficacy of the ELAD System (ELAD) to Treat Acute Liver Failure (ALF)

Acute Liver Failure | Fulminant Hepatic Failure | Primary Graft Non-Function | Surgically-Induced Liver Failure

United States
Columbia University

Withdrawn

Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever

Liver Failure | Liver Failure, Acute | Fever | Prevention & Control | Drug Induced Liver Injury

United States
Miromatrix Medical Inc.

Not yet recruiting

miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial

Acute Liver Failure | Acute Liver Injury, Drug Induced

United States
Ceryx Medical Australia
Avania

Not yet recruiting

Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF (RSA-PACE)

Heart Failure With Reduced Ejection Fraction

New Zealand
Institute of Liver and Biliary Sciences, India

Completed

High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure

Acute Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF).

Acute Liver Failure | Acute on Chronic Liver Failure

India
Govind Ballabh Pant Hospital

Unknown

Granulocyte Colony Stimulating Factor(G-CSF) Therapy for Patients With ACLF

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Prognostic Significance of Acute Change in Liver and Splenic Stiffness in Patients of Acute on Chronic Liver Failure

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Recruiting

Acute Hemodynamic Response to Carvedilol in Predicting Survival in Acute on Chronic Liver Failure Patients - A Pilot Study.

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy of Albumin Plus Midodrine v/s Albumin Alone in Reducing Incidence of Paracentesis Induced Circulatory Dysfunctions in ACLF Patients.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure.

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Study the Role of Plasma Von Willebrand Factor Antigen (vWF) to A Disintegrin-like and Metalloproteinase With Thrombospondin Type-1 Motifs 13 (ADAMTS-13) Activity Ratio as a Predictor of Development of Extrahepatic Organ Failure in Acute on Chronic Liver Failure (ACLF) Patients.

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy of Albumin Therapy With Standard Medical Treatment (SMT) as Compared to Standard Medical Treatment (SMT) in Improving Patient Survival and Immune Modulation in Patients With Acute on Chronic Liver Failure (ASIA Trial).

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver Failure

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Withdrawn

To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF).

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Terminated

To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute Phase

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Determine the Predictors of Reversibility for Acute-on-Chronic Liver Failure at 6-months.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Acute hemodynamiC Response To Carvedilol Predicts Survival in ACLF Patients

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

To Study the Immunomodulating Effects and Safety Profile of ω3 and ω6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure

Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Recruiting

Role of Fecal Microbiota in Predicting Graft Rejection and Sepsis Among Recipients of Living Donor Liver Transplant in First Year.

Liver Cirrhosis | Acute-On-Chronic Liver Failure | Acute Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure

Cirrhosis | Chronic Liver Failure | Acute Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure

Acute on Chronic Hepatic Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Lactate Kinetics as a Predictor of Survival in ACLF With Septic Shock

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Assessment of Coagulation Profile and Haematopoietic Responses in Patients With Acute-on-chronic Liver Failure During Systemic Inflammatory Response (SIRS) and Sepsis

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment Response

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Withdrawn

To Assess the Role of Fecal Microbiota Transplant in Acute Liver Failure

Acute Liver Failure

India
Conatus Pharmaceuticals Inc.

Terminated

Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF

Liver Cirrhosis | Acute on Chronic Hepatic Failure | Acute Liver Failure | Acute Alcoholic Hepatitis

United States, United Kingdom
Institute of Liver and Biliary Sciences, India

Completed

Bowel Colonization With Multi-drug Resistant Bacterial Species in Hospitalized Patients With acute-on Chronic Liver Failure (ACLF), and Its Relationship With Extra-intestinal Infectious Events and Short-term Outcomes.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy.

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure

Acute Liver Failure

India
Mylan Specialty, LP

Terminated

Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning

Liver Failure | Amatoxin Poisoning | Amanita Poisoning | Mushroom Poisoning

United States
Institute of Liver and Biliary Sciences, India

Recruiting

To Compare Relaxed Rotational Thromboelastometry Cut-offs With Standard Cut-offs for Guiding Blood Product Use Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure Patients

Liver Cirrhosis | Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Withdrawn

To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.

Cirrhosis

India
All India Institute of Medical Sciences, New Delhi

Unknown

Assessment of Coagulation Abnormalities in Acute on Chronic Liver Failure Patients Using Thromboelastography

Cirrhosis | Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Utility of Liver and Splenic Stiffness in Predicting Esophageal Varices in Patients With Acute on Chronic Liver Failure

Acute-On-Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Completed

Efficacy of Nonselective Beta Blocker vs Placebo in Patients With Acute-on-chronic Liver Failure With Small/ no Esophageal Varices

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of L-ornithine L-aspartate and Therapeutic Plasma Exchange Versus Plasma Exchange Alone in Lowering Ammonia and Improving Outcomes in Pediatric Acute Liver Failure.

Liver Failure, Acute

India
Institute of Liver and Biliary Sciences, India

Completed

To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure

Acute on Chronic Liver Failure

India
Sir Ganga Ram Hospital

Unknown

Evaluation of Role of Transient Elastography (Fibroscan) in Differentiating Patients of Acute Severe Viral Hepatitis and Acute on Chronic Liver Failure (ACLF)

Acute on Chronic Liver Failure | Acute Severe Viral Hepatitis

India
Institute of Liver and Biliary Sciences, India

Completed

Efficacy of Early Terlipressin Plus Albumin Therapy in Comparison to Standard Treatment for HRS-AKI in Acute-on-chronic Liver Failure.

Acute-On-Chronic Liver Failure | Acute Kidney Injury | Hepatorenal Syndrome

India
Grifols Therapeutics LLC
Instituto Grifols, S.A.

Recruiting

Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5% (APACHE)

Acute-On-Chronic Liver Failure

United States, United Kingdom, Spain, Germany, Italy, Belgium, France, Austria, Denmark, Portugal
Eli Lilly and Company

Recruiting

A Study of LY3437943 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Institute of Liver and Biliary Sciences, India

Completed

Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure.

Acute on Chronic Liver Failure

India
Institute of Liver and Biliary Sciences, India

Recruiting

Efficacy of Addition of Fecal Microbiota Transplant (FMT) and Plasma Exchange to Tenofovir in Comparison to Monotherapy With Tenofovir in ACLF-HBV

Acute-On-Chronic Liver Failure | Hepatitis B

India
European Foundation for Study of Chronic Liver...

Recruiting

Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs (CHANCE)

Liver Diseases | Liver Cirrhosis | Acute-On-Chronic Liver Failure | Liver Transplant; Complications

Spain, United States, Germany, Belgium, United Kingdom, Japan, Mexico, Taiwan, Korea, Republic of, Canada, France, Australia, Italy, Argentina, Austria, Brazil, Colombia, Czechia, Hong Kong, India, Netherlands, New Zealand, Poland, Po... and more
Institute of Liver and Biliary Sciences, India

Terminated

Efficacy of N-acetylcysteine With or Without Steroids in Drug Induced Liver Injury

Drug Induced Liver Injury

India
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Incidence and Predictors of Bleeding Diathesis Development Due to DIC in Cirrhosis and ACLF Patients Undergoing CRRT

Acute-On-Chronic Liver Failure

India
St. Luke's-Roosevelt Hospital Center

Completed

Transplant and Addiction Project (TAP) - 1

Substance-Related Disorders | End Stage Liver Disease | End Stage Renal Disease

United States
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy and Safety of Plasma Exchange Compared to Standard Medical Therapy in Patients With Severe Drug Induced Liver Injury With or Without Underlying Chronic Liver Disease.

Chronic Liver Disease

India
Govind Ballabh Pant Hospital

Completed

Randomized Controlled Trial of Tenofovir in Patients of Reactivation of Hepatitis B Presenting as Acute on Chronic Liver Failure (ACLF)

Hepatitis B | Acute on Chronic Liver Failure

India

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