Clinical Trials on Temporal Lobe Epilepsy

Total 3333 results

University of Campinas, Brazil

Recruiting

Safety and Efficacy of Topical Moxifloxacin for Prevention of Post-Traumatic Endophthalmitis: Randomized Controlled Clinical Trial

Endophthalmitis | Moxifloxacin | Open Globe Injury | Post-Traumatic Endophthalmitis

Brazil
Stanford University
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Transcranial Magnetic Stimulation for BECTS (TMS4BECTS)

Learning Disorders | Benign Epilepsy With Centrotemporal Spikes | Language Problems

United States
Ege University

Completed

The Effect of Jigsaw Technique on Childhood Epileptic Seizure Management Knowledge and Attitudes of Nursing Students

Epilepsy in Children | Nursing Student | Jigsaw Technique

Turkey
UCB Biopharma S.P.R.L.
Pharm Research Associates (UK) Ltd.

Completed

Study to Look at How Effective Briviact is as add-on Treatment for Patients With Epilepsy With Partial Onset Seizures (BASE)

Epilepsy With POS With or Without Secondary Generalization

Denmark, Germany, Hungary, Ireland, Italy, Netherlands, Norway, Spain, United Kingdom
UCB BIOSCIENCES, Inc.

Completed

Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset Seizures

Partial Epilepsies | Partial Onset Seizures

United States
Fudan University
Peking University First Hospital; Xiangya Hospital of Central South University and other collaborators

Unknown

Omics-based Precision Medicine of Epilepsy

Gene Mutation | Epilepsy Idiopathic | Clinical Disease and/or Syndrome

China
UCB BIOSCIENCES, Inc.

Completed

Study to Assess the Long-term Safety of Oral Lacosamide in Subjects With Partial-onset Seizures

Partial Epilepsies | Partial Onset Seizures

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Creatine Deficiency Syndromes (BioCDS) (BioCDS)

Intellectual Disability | Developmental Delay | Intractable Epilepsy | Movement Disorder | Behavioral Disorder

India, Sri Lanka, Egypt
Lancashire Teaching Hospitals NHS Foundation Trust

Recruiting

Neurofrailty: A Study of Late-onset Epilepsy and Its Associations

Stroke | Dementia | Late Onset Epilepsy

United Kingdom
Xijing Hospital

Enrolling by invitation

The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients

Epileptic Seizures Related to Drugs

China
Second Affiliated Hospital, School of Medicine,...

Completed

Association of Processing Speed Dysfunction and Brain Functional Abnormality in ECTS

Epilepsy, Rolandic

China
National Institute of Neurological Disorders and...

Completed

MRI in Autosomal Dominant Partial Epilepsy With Auditory Features

Epilepsies, Partial

United States
Assistance Publique - Hôpitaux de Paris
OSO-AI

Recruiting

Characterization by Automated System on Infantile Spasmes (REASSESS)

Infantile Spasm

France
UCB BIOSCIENCES, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome (ORCHID)

Dravet Syndrome

United States
Cook Children's Health Care System
Encoded Therapeutics

Recruiting

GABA Biomarkers in Dravet Syndrome

Dravet Syndrome

United States
Hospices Civils de Lyon

Recruiting

Neurodevelopmental Impact of Epilepsy on Autonomic Function in Dravet Syndrome (AUTONOMIC)

Epilepsy | Dravet Syndrome

Belgium, France, Germany
Stoke Therapeutics, Inc

Enrolling by invitation

An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome

Dravet Syndrome

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Neuronal Excitability of HCN1 Channel Mutations in Dravet Syndrome (EXCIDRAH)

Dravet Syndrome

France
Jazz Pharmaceuticals

Completed

Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

France, United States, United Kingdom, Poland
INSYS Therapeutics Inc

Withdrawn

Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Participants With Inadequately Controlled Dravet Syndrome

Dravet Syndrome
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Boston Children's Hospital
Encoded Therapeutics

Recruiting

Transcranial Magnetic Stimulation to Measure Cortical Excitability in Dravet Syndrome

Dravet Syndrome

United States
Stoke Therapeutics, Inc

Completed

An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome

Dravet Syndrome

United States
Fondazione Policlinico Universitario Agostino Gemelli...
IRCCS San Raffaele

Enrolling by invitation

EXploring novEl Molecular Determinants of DRAvet Syndrome Phenotype Heterogeneity (EXEDRA)

Dravet Syndrome

Italy
Jazz Pharmaceuticals

Terminated

Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures

Seizures Associated With EMAS

United States, Italy
Zogenix International Limited, Inc., a subsidiary...

Completed

An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome

Dravet Syndrome

United States, United Kingdom, Spain, Belgium, Italy, Australia, Denmark, Germany, Canada, Japan, Netherlands, France
Gillette Children's Specialty Healthcare
Mayo Clinic; Dartmouth-Hitchcock Medical Center; Ann & Robert H Lurie Children...

Completed

Verapamil as Therapy for Children and Young Adults With Dravet Syndrome

Dravet Syndrome

United States
University of California, Los Angeles

Available

Treatment of Dravet Syndrome With Fenfluramine (Expanded Access Protocol) (Dravet)

Dravet Syndrome

United States
IRCCS San Raffaele

Not yet recruiting

Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy

Epilepsy | Focal Epilepsy

Italy
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Dravet Syndrome

Australia
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome (ENDEAVOR)

Dravet Syndrome

United States
Epygenix
Forest Hills Lab; Liberyx Therapeutics

Recruiting

EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome (ARGUS)

Dravet Syndrome

United States, Canada, Spain, Georgia, Hungary
Zogenix, Inc.

Approved for marketing

ZX008 Expanded Access Protocol

Dravet Syndrome
Zogenix International Limited, Inc., a subsidiary...

Completed

A 2-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children ≥ 2 Years Old and Young Adults With Dravet Syndrome

Dravet Syndrome

United States, France, United Kingdom, Canada, Germany, Netherlands, Spain
Jazz Pharmaceuticals

Completed

A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

United States, United Kingdom
Jazz Pharmaceuticals

Completed

GWPCARE2 A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet Syndrome

Epilepsy | Dravet Syndrome

United States, Spain, Israel, Poland, Australia, Netherlands
University of Colorado, Denver

No longer available

Compassionate Use of Stiripentol in Dravet Syndrome

Dravet Syndrome

United States
Children's Hospital Medical Center, Cincinnati

Approved for marketing

Treatment Plan to Provide Expanded Access to Stiripentol for Patients With Dravet Syndrome

Dravet Syndrome

United States
H. Lundbeck A/S

Terminated

Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

Dravet Syndrome

United States, Mexico
H. Lundbeck A/S

Withdrawn

Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

Dravet Syndrome

United States, Mexico
Mayo Clinic

No longer available

Stiripentol in Dravet Syndrome

Dravet Syndrome

United States
University Hospital, Bordeaux
Institut National de la Santé Et de la Recherche Médicale, France; Centre National...

Recruiting

Electroclinical Correlation of Anxiety (IRAnxNet)

Generalized Anxiety Disorder | Drug Resistant Epilepsy | Anxiety Disorder

France
University of Iowa

Recruiting

Carbon Dioxide (CO2) Chemosensitivity and SUDEP

Epilepsy | SUDEP

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients

Epilepsy | Epilepsy, Generalized | Seizures | Epilepsies, Partial
All India Institute of Medical Sciences, New Delhi

Recruiting

Cortical Excitability in West Syndrome Using Transcranial Magnetic Stimulation

West Syndrome

India
NEMA Research, Inc.

Terminated

Efficacy and Safety of Intravenous Phenobarbital in Neonatal Seizures

Epilepsy, Benign Neonatal

United States, Jordan
UCB BIOSCIENCES GmbH
PRA Health Sciences

Completed

Study of Lacosamide as an Adjunctive Drug Treatment for Epilepsy in Patients With Brain Tumors (VIBES)

Brain Tumor Related Epilepsy (BTRE)

Italy, France, Germany, Netherlands, Spain, United Kingdom
Shaare Zedek Medical Center

Unknown

Sensitivity and Specificity of Color Doppler Directed Temporal Artery Biopsy as Compared to Standard Random Biopsy in the Diagnosis of Temporal Arteritis

Temporal Arteritis | Duplex of Temporal Artery | Biopsy of Temporal Artery

Israel
Sundsvall Hospital

Completed

Comparison of a Cemented, Polished Tapered Stem and an Anatomic Stem for Femoral Neck Fracture

Hip Fracture | Femoral Neck Fracture | Periprosthetic Femoral Fracture
KTO Karatay University

Completed

The Individual and Family Self Management Theory Based Epilepsy Education Program's Effectiveness

Quality of Life | Epilepsy; Seizure | Self Management

Turkey

Clinical Trials on Temporal Lobe Epilepsy

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Medical Conditions

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CROs in Norway

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