Clinical Trials on Thalassemia Trait

Total 105913 results

Affiliated hospital of guangxi medical university...
Zhongshan Hospital Xiamen University; The Affiliated Nanjing Drum Tower Hospital... and other collaborators

Unknown

Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia Major

Beta-Thalassemia Major

China
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Disorders | Hb-SS Disease | Hemoglobin S | Disease Sickle Cell Anemia | Hemoglobin Beta Thalassemia Disease

United States
Shire

Withdrawn

Treatment of Iron Overload Requiring Chelation Therapy

Metabolic Diseases | Iron Metabolism Disorders | Iron Overload | Beta-thalassemia | Transfusional Hemosiderosis | Transfusional Iron Overload | Iron Chelation
Federal Research Institute of Pediatric Hematology...

Unknown

the Efficacy and Safety of Sugammadex in Children 0-2 Years Old

Anesthesia | Pediatric Cancer | Beta-Thalassemia | Hepatic Metastases | Pediatric Tumor | Pediatric Hepatoblastoma

Russian Federation
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Cardiac Iron Overload | Transfusion-dependent β-thalassemia Patients

Greece
Emory University
Patient-Centered Outcomes Research Institute

Completed

Decision Aid for Therapeutic Options In Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Hemoglobin SC | Hemoglobin SS | Hemoglobin Beta Thalassemia

United States
Assiut University

Completed

Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients

Thalassemia

Egypt
Hematology department of the 920th hospital

Recruiting

Clinical Observation of Luspatercept in Treatment of Chinese Adult β-thalassaemia Patients With TD β-thalassemia

Effect of Drug

China
Novartis Pharmaceuticals

Completed

Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible Tablet (Jupiter)

Non-transfusion-dependent Thalassemia | Transfusion-dependent Thalassemia

Egypt, Turkey, Thailand, Lebanon, Morocco, Saudi Arabia, Vietnam
Ain Shams University

Completed

Congenital Heart Surgery in Pediatric Patients With Beta-Thalassemia Major

Hemolysis
Novartis Pharmaceuticals

Completed

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Transfusional Iron Overload | β-thalassemia Major | Pediatric Rare Anemia

Italy, France
Novartis

Completed

A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional Hemosiderosis

Beta-Thalassemia | Hemosiderosis

Egypt, Lebanon, Oman, Saudi Arabia, Syrian Arab Republic
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); Thalassemia Clinical Research...

Completed

Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)

Hematologic Diseases | Iron Overload | Hypertension, Pulmonary | Osteoporosis | Thalassemia | Beta-Thalassemia | Anemia, Cooley's

United States, Canada
Silence Therapeutics plc

Withdrawn

Study in Beta-thalassaemia or Myelodysplastic Syndrome Patients to Investigate the Safety and Tolerability of SLN124

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome

United Kingdom, Bulgaria
Ain Shams University

Unknown

Role of Vitamin C to Augment Iron Chelation With DFP or DFX

Thalassemia Major | Iron Chelation | Vitamin c

Egypt
University of Milano Bicocca

Completed

Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological Diseases (ThalaCoV)

Covid19 | Thalassemia Major

Italy
Novartis Pharmaceuticals

Completed

Post Hematopoietic Stem Cell Transplantation

Iron Overload After Hematopoietic Stem Cell Transplantation (HSCT) in Patients With Beta-thalassemia Major

Turkey
Wolfson Medical Center

Unknown

GDF 15 in Sickle Cell Disease and Hereditary Spherocytosis (GDF 15)

Patients With Thalassemia Intermedia, | Congenital Dyserythropoietic Anemia Type I
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Sickle Cell Disease | Thalassemia | Thalassemia, Beta

United States
Timothy Olson

Active, not recruiting

Pilot Study PBSCT With TCRab Depletion For Hemoglobinopathies

Sickle Cell Disease | Thalassemia Major

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Longitudinal Study on the QoL of Pediatric Patients After HSCT and Its Influencing Factors

Acute Leukemia | Thalassemia Major

China
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Sickle Cell Anemia | Beta Thalassemia

United States
Columbia University

Active, not recruiting

Stem Cell Transplant in Sickle Cell Disease and Thalassemia

Sickle Cell Disease | Beta Thalassemia

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia

Anemia, Sickle Cell | Hemoglobinopathies | Thalassemia | Hemoglobin SC Disease | Thalassemia Major

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Malaria | Sickle Cell Disease | Alpha and Beta Thalassemia | Human Physiology

United States
Tanta University

Completed

Effect of Spirulina on Serum Hyaluronic Acid in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Ain Shams University

Completed

Zinc Supplementation in Patients With β-Thalassemia Major Complicated With Diabetes Mellitus

Beta-thalassemia Major Complicated With Diabetes

Egypt
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis

Hematologic Diseases | Iron Overload | Hemoglobinopathies | Thalassemia | Beta-Thalassemia | Hemochromatosis | Anemia (Iron-Loading)
Tanta University

Completed

Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Novartis Pharmaceuticals

Completed

Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration) (ESCALATOR)

Iron Overload | Hemosiderosis | Beta-thalassemia Major | Rare Anemia

Egypt, Oman, Saudi Arabia, Syrian Arab Republic, Lebanon
Assiut University

Not yet recruiting

NAC Effect on Iron Overload and Blood Transfusion in β-thalassemia Major

Thalassemia Major
Ain Shams University

Recruiting

PK of SOF/LED in HCV - Infected Adolescents With Haematological Disorders

HCV Infection | Beta Thalassemia Major

Egypt
Silence Therapeutics plc

Completed

A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome | Very-Low Risk Myelodysplastic Syndrome

Thailand, Israel, Jordan, United Kingdom, Germany, Italy, Malaysia
Beni-Suef University

Completed

The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia Major

Thalassemia Major

Egypt
HaEmek Medical Center, Israel

Unknown

A Case Control Study to Evaluate the Cognitive and Brain Function of β-thalassemia Patients.

Thalassemia | Brain Function (Measured by ERP Level)

Israel
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major (AmloThal)

Iron Overload | Thalassemia

Brazil
Azienda Ospedaliero-Universitaria di Modena

Recruiting

"Iron Overload and Endocrinological Diseases"

Iron Overload | Hemochromatosis | Thalassemia Major | Thalassemia Intermedia | Endocrinopathy

Italy
Celgene

Recruiting

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Beta-thalassemia | Myelodysplastic Syndromes (MDS) | Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis

United States, Japan, United Kingdom, Turkey, Greece, France, Australia, Belgium, Bulgaria, Canada, Germany, Israel, Italy, Malaysia, Spain, Sweden, Taiwan, Thailand, Tunisia, Lebanon, China, Netherlands
Novartis Pharmaceuticals

Completed

Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload

Myelodysplastic Syndromes | Beta-Thalassemia

Hungary
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India

Anemia

India
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major (AnloThal)

Thalassemia Major

Brazil
Beni-Suef University
University of Arizona; Maternity and Children Hospital, Makkah; Beni-Suef Health...

Completed

Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia

Iron Overload | Oxidative Stress | Thalassemia Major

Egypt, Saudi Arabia
Tanta University

Completed

Hyalornic Acid Level in β-Thalassemic Children Treated for Hepatitis C Virus

Hepatitis C | Beta-Thalassemia

Egypt
Tanta University

Completed

Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C

Beta Thalassemia Major

Egypt
Ain Shams University

Unknown

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Sickle Cell Disease | Beta-thalassemia Major | Iron Hemosiderosis

Egypt
University Hospital of Ferrara

Recruiting

Atrial Fibrillation in Beta-Thalassemia

Atrial Fibrillation | Thalassemia

Italy
National Center for Research Resources (NCRR)
Children's Hospital of Philadelphia

Completed

Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia Major

Osteoporosis | Osteopenia | Thalassemia Major
Sangamo Therapeutics

Enrolling by invitation

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Blood and Lymphatic Diseases

United States
King Saud University

Completed

Periodontal Therapy in Thalassemia Major Patients

Chronic Periodontitis | Thalassemia Major
University of Thessaly

Completed

Resistance Exercise on Postprandial Hyperglycemia in Patients With B-thalassemia Exhibiting Resistance to Insulin

Diabetes Mellitus, Type 2 | Insulin Resistance | PreDiabetes | Beta-Thalassemia

Greece

Clinical Trials on Thalassemia Trait

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Medical Conditions

Drug Interventions

CROs by country

CROs in Poland

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