Clinical Trials on Thrombocytopenia; Drugs

Total 4059 results

Children's Hospital of Philadelphia

Completed

Sirolimus for Autoimmune Disease of Blood Cells

Rheumatoid Arthritis | Lupus Erythematosus, Systemic | Idiopathic Thrombocytopenic Purpura | Inflammatory Bowel Disease | Anemia, Hemolytic, Autoimmune | Evans Syndrome | Autoimmune Pancytopenia | Autoimmune Lymphoproliferative Syndrome (ALPS) | Autoimmune Neutropenia

United States
University of Louisville
James Graham Brown Cancer Center

Terminated

Fondaparinux for the Treatment of Heparin-Induced Thrombocytopenia (HIT)

Heparin-Induced Thrombocytopenia

United States
Amgen

Withdrawn

Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Lymphoma.

Chemotherapy-induced Thrombocytopenia
Mohamed Elsayed
University of Alexandria

Unknown

Ultrasound Guided Erector Spinae Plane Block Combined With General Anaesthesia Versus Conventional General Anaesthesia in Lumbar Spine Surgery (US ESP block)

Anaesthetic Drugs, Hypotensive Drugs, Perioperative Analgesia

Egypt
The Medicines Company

Withdrawn

Bivalirudin PCI Registry in Heparin Induced Thrombocytopenia/Heparin Induced Thrombocytopenia and Thrombosis Syndrome (HIT/HITTS) Patients

Heparin-Induced Thrombocytopenia | Heparin-induced Thrombocytopenia and Thrombosis Syndrome

United States
Karyopharm Therapeutics Inc

Recruiting

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia (SENTRY-2)

Myelofibrosis | Moderate Thrombocytopenia

United States
Sun Yat-sen University

Not yet recruiting

Hetrombopag in Secondary Prevention of XPO-1 Inhibitor-induced Thrombocytopenia in Lymphoma

Chemotherapy-Induced Thrombocytopenia
Ministry of Health, Labour and Welfare, Japan
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety Study of Argatroban to Treat Heparin-Induced Thrombocytopenia

Heparin-Induced Thrombocytopenia

Japan
Terumo BCTbio
Biomedical Advanced Research and Development Authority

Terminated

Efficacy of Mirasol-treated Apheresis Platelets in Patients With Hypoproliferative Thrombocytopenia (MIPLATE)

Hematologic Malignancies | Hypoproliferative Thrombocytopenia

United States
Leiden University Medical Center
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research

Unknown

Neurodevelopmental Outcome After Fetal Neonatal AlloImmune Thrombocytopenia (NOFNAIT)

Neurodevelopmental Abnormality | Fetal and Neonatal Alloimmune Thrombocytopenia | Long Term Adverse Effects | Intravenous Immunoglobulin Adverse Reaction

Netherlands
Xijing Hospital

Enrolling by invitation

The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients

Epileptic Seizures Related to Drugs

China
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Eisai Inc.

Completed

Treatment of Thrombocytopenia in Patients With Chronic Liver DiseaseUndergoing an Elective Procedure

Thrombocytopenia Associated With Liver Disease

United States, Italy, China, Taiwan, Spain, Belgium, Poland, Portugal, Canada, Korea, Republic of, Australia, Brazil, Chile, Austria, Germany, Hungary, France, Argentina, United Kingdom, Thailand
Azienda Sanitaria-Universitaria Integrata di Udine

Unknown

Immune Thrombocytopenia (ITP) Immune-Genetic Assessment (UNIT)

Thrombocytopenia

Italy
Eisai Co., Ltd.

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Once-daily Oral Avatrombopag in Japanese Subjects With Chronic Liver Diseases and Thrombocytopenia

Thrombocytopenia Associated With Chronic Liver Disease

Japan
Eisai Inc.

Completed

Once-Daily Oral Avatrombopag Tablets Used in Subjects With Chronic Liver Diseases and Thrombocytopenia Prior to Elective Surgical or Diagnostic Procedures

Thrombocytopenia Related to Chronic Liver Disease

United States
Jianxiang Wang
Xian-Janssen Pharmaceutical Ltd.

Unknown

Therapeutic Effect and Safety Study of Decitabine in Elderly Acute Myeloid Leukemia Patients

Untreated Adult Acute Myeloid Leukemia | Effect of Drugs | Drug Safety
Mario Negri Institute for Pharmacological Research

Completed

E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF (SIM-AF)

Atrial Fibrillation | Elderly | Geriatrics | Simulation Training | Anticoagulant Drugs | Internal Medicine | Drug Prescriptions

Italy
Faculty of Medicine

Completed

Uterotonic Efficacy of Oxytocin 2.5 Versus 10 Units During Caesarean Section at Mulago Hospital

Uterine Hemorrhage | Adverse Effect of Oxytocic Drugs | Inappropriate Dose of Drug Administered

Uganda
Hospital Clinic of Barcelona

Unknown

ELIGIBLE (Efficacy of Left atrIal Appendage Closure After GastroIntestinal BLEeding) (ELIGIBLE)

Adverse Reaction to Drugs Affecting the Gastrointestinal System

Spain
Second Hospital of Shanxi Medical University

Not yet recruiting

Clinical Study on the Efficacy and Safety of Hetropapa Ethanolamine Tablets in the Treatment of Thrombocytopenia Caused by Concurrent Radiotherapy and Chemotherapy in Cervical Cancer

Tumor Chemotherapy-related Thrombocytopenia

China
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias

Immune Mediated Anemia | Immune Mediated Thrombocytopenia | Chronic GVHD

United States
Eisai Inc.

Completed

Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure

Thrombocytopenia Associated With Liver Disease

United States, China, Spain, Argentina, Belgium, Israel, Mexico, Romania, Japan, Brazil, Russian Federation, Germany, Italy, Czechia, Canada, Australia, France
Archemix Corp.

Completed

ARC1779 Injection in Patients With Von Willebrand Factor-Related Platelet Function Disorders

Purpura, Thrombotic Thrombocytopenic | Von Willebrand Disease Type-2b

Austria
Centre Hospitalier Universitaire, Amiens

Recruiting

Characterization and Quantification of Platelet/Leukocyte Aggregates in Patients With Suspected Heparin-induced Thrombocytopenia (HITSTREAM)

Heparin-induced Thrombocytopenia | Platelet Activation | Platelets | Leukocytes | HIT | Platelet/Leukocyte Aggregates | HITSTREAM | Flow Cytometry

France
University Medicine Greifswald
Novartis

Unknown

The HIT-TRAP Trial

Heparin-Induced Thrombocytopenia

Germany
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias

Immune Mediated Anemia | Immune Mediated Thrombocytopenia | Chronic GVHD

United States
Liaoning Tumor Hospital & Institute

Completed

To Evaluate Thrombosis Risk in Chemotherapy Patients With Solid Tumors Who Receiving Thrombocytopenia Treatment

Chemotherapy-induced Thrombocytopenia

China
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Drug Etiology of Aplastic Anemia and Related Dyscrasias

Purpura, Thrombocytopenic | Agranulocytosis | Anemia, Aplastic | Blood Disease
Ramsay Générale de Santé
European Clinical Trial Experts Network

Not yet recruiting

Multicenter Study on Dialysis Modalities for End-stage Chronic Renal Failure Patients With Heparin-induced Thrombocytopenia (MODIATIH)

Chronic Renal Failure | Heparin-induced Thrombocytopenia | Dialysis; Complications

France
The Medicines Company

Completed

Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning)

Thrombosis | Heparin-Induced Thrombocytopenia

United States
Universiti Sains Malaysia

Completed

Recombinant Activated Factor VII in the Management of Massive Bleeding in Hospital Universiti Sains Malaysia

Massive Hemorrhage | Massive Blood Loss | Massive Blood Transfusion; Thrombocytopenia

Malaysia
Medical College of Wisconsin

Completed

Registry for Vascular Anomalies Associated With Coagulopathy (VAC)

Hemangiomas | Multifocal Lymphangioendotheliomatosis With Thrombocytopenia | Cutaneovisceral Angiomatosis With Thrombocytopenia | Vascular Anomaly With Thrombocytopenia

United States
Leiden University Medical Center
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Sanquin...

Recruiting

PRedicting OutcomeS in Preterm nEonates With thromboCyTopenia (PROSPECT) (PROSPECT)

Intraventricular Hemorrhage | Neonatal Thrombocytopenia | Platelet Transfusion

Netherlands, Sweden
Brigham and Women's Hospital
Mitsubishi Tanabe Pharma Corporation

Completed

Heparin-Induced Thrombocytopenia Registry (HIT)

Heparin-Induced Thrombocytopenia

United States
Johann Wolfgang Goethe University Hospital

Unknown

Generation of Heparin-induced Thrombocytopenia (HIT)-Antibodies Without Prior Heparin Exposure

Thrombosis | Heparin-Induced Thrombocytopenia

Germany
Hanny Al-Samkari, MD
Swedish Orphan Biovitrum

Recruiting

Avatrombopag vs. Placebo for CIT in GI Malignancies (ACT-GI)

Gastrointestinal Neoplasms | Gastrointestinal Cancer | Chemotherapy-Induced Thrombocytopenia

United States
Wuhan Asia Heart Hospital

Unknown

Thrombotic Biomarkers to Predict Thrombosis in Heparin-induced Thrombocytopenia

Thrombosis | Biomarkers | Heparin-Induced Thrombocytopenia
Jung-min Ahn
CardioVascular Research Foundation, Korea

Active, not recruiting

Perioperative Antiplatelet Therapy in Patients With Drug-eluting Stent Undergoing Noncardiac Surgery (ASSURE-DES)

Antiplatelet Drugs

Korea, Republic of, India, Turkey
National Taiwan Normal University

Completed

The Effectiveness of 3D VR Training System for Supporting Volunteers on Adolescents' Illegal Drug Use

Illicit Drugs

Taiwan
Tongji Hospital

Recruiting

A 6-month Follow-up Study of Patients With Severe Fever With Thrombocytopenia Syndrome

Severe Fever With Thrombocytopenia Syndrome

China
Qin Ning

Recruiting

Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome(SFTS)

Severe Fever With Thrombocytopenia Syndrome

China
Shandong University
The Affiliated Hospital of the Chinese Academy of Military Medical Sciences; Shenzhen Second People's Hospital and other collaborators

Completed

A Prospective, Open, Multicenter Clinical Trial of Eltrombopag Combined With Diacerein in Eltrombopag-inefficient or Relapsed ITP

Thrombocytopenia

China
Stanford University

Completed

Effects of a Platelet Transfusion Best Practices Alert

Thrombocytopenia

United States
Maastricht University Medical Center

Completed

Post-Operative Thrombocytopenia After Bio-prosthesis Implantation (PORTRAIT)

Thrombocytopenia

Netherlands
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

American Trial Using Tranexamic Acid in Thrombocytopenia (A-TREAT)

Thrombocytopenia

United States
The First Affiliated Hospital of Soochow University
Peking University People's Hospital; Qilu Hospital of Shandong University; Nanfang... and other collaborators

Completed

Prospective Study of Patients With Thrombocytopenia Following HSCT

Hematologic Diseases | Thrombocytopenia

China
First Affiliated Hospital Xi'an Jiaotong University
Shenyang Pharmaceutical University

Unknown

High-dose Use of rhTPO in CIT Patients (HUrhTPOCITP)

Thrombocytopenia

China
Sanquin Research & Blood Bank Divisions
Terumo BCT

Completed

Pathogen Reduction Evaluation & Predictive Analytical Rating Score (PREPAReS)

Thrombocytopenia

Netherlands, Norway, Canada
University of Oklahoma

Completed

Study of the Effect of Differing Platelet Transfusion Times in Neonates

Thrombocytopenia

United States

Clinical Trials on Thrombocytopenia; Drugs

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