Clinical Trials on Tolerability, Safety, Immunogenicity and Pharmacokinetic of JS005

Total 301 results

Chulalongkorn University
HIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...

Recruiting

Immunogenicity and Safety of Comvigen (Bivalent) Vaccine

Safety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...

Thailand
Annexon, Inc.
Nucleus Network Ltd

Completed

A Single and Multiple Ascending Dose Study of ANX009 in Normal Healthy Volunteers (NHV)

Safety and Tolerability in Healthy Volunteers

Australia
Shanghai General Hospital, Shanghai Jiao Tong University...

Not yet recruiting

An Exploratory Clinical Trial Evaluating LX109 Gene Therapy in Patients With nAMD

To Evaluate the Safety and Tolerability of Intravitreal Injection of LX109 in Patients With nAMD
University of Hohenheim
German Federal Ministry of Education and Research

Completed

Oral Bioavailability of Curcumin From Micronized Powder and Liquid Micelles in Healthy Young Women and Men

Pharmacokinetics of Novel Curcumin Formulations | Safety of Novel Curcumin Formulations

Germany
Sylentis, S.A.

Completed

Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops

Choroidal Neovascularization | Safety, Tolerability and Pharmacokinetic Profile in Healthy Volunteers

Spain
CytaCoat AB

Recruiting

Evaluation of Safety and Performance of the CytaCoat Lubricious Infection Prevention (LIP) Foley Catheter

Safety of the CytaCoat LIP Foley Catheter | Tolerability of the CytaCoat LIP Foley Catheter

Sweden
Stemirna Therapeutics

Not yet recruiting

A Phase II/III Study to Evaluate the Immunogenicity and Safety and Efficacy of SWIM816 Vaccines for SARS-CoV-2

Safety | Immunogenicity
Stemirna Therapeutics

Active, not recruiting

mRNA Booster Vaccine(SW-BIC-213) Compared With Pfizer andSinopharm Against Emerging VOCs

Efficacy | Safety | Immunogenicity

Lao People's Democratic Republic
Theracos

Completed

Study to Determine the Safety, Tolerability, and Pharmacokinetic (PK) Profile of EGT0001474 in Healthy Volunteers

Safety and Tolerability of EGT0001474 in Healthy Volunteers

United States
Medibiofarma S.L.

Completed

Study to Assess the Safety and Tolerability of MBF-015 in Healthy Young Volunteers

Safety and Pharmacokinetic

Spain
Chulalongkorn University
BioNet-Asia; Chula Clinical Research Center (Chula CRC), Faculty of Medicine... and other collaborators

Recruiting

Safety and Immunogenicity of ChulaCov19 BNA159 mRNA Vaccine

Safety of 25 ug of ChulaCov19-BNA159 mRNA Vaccine | Tolerability of 25 ug of ChulaCov19-BNA159 mRNA Vaccine | Immune Response of 25 ug of ChulaCov19-BNA159 mRNA Vaccine | Safety of 50 ug of ChulaCov19-BNA159 mRNA Vaccine | Tolerability of 50 ug of ChulaCov19-BNA159 mRNA Vaccine | Immune Response... and other conditions

Thailand
Sensimed AG

Completed

SENSIMED Triggerfish Discomfort During IOP Monitoring (09/02)

Safety and Tolerability of SENSIMED Triggerfish in Glaucoma Patients

Germany
Stemirna Therapeutics

Recruiting

New Generation mRNA Booster Vaccine Against Emerging VOCs

Efficacy | Safety | Immunogenicity

Lao People's Democratic Republic
AstraZeneca

Completed

A Single Ascending Dose Study To Assess The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of AZD9567.

Rheumatoid Arthritis | Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Germany
Nobelpharma

Completed

An Additional Study of NPC-22 in Healthy Adult Males

Safety and Pharmacokinetics

Japan
LG Chem

Completed

6x3 Crossover, Bioavailability, Safety and Tolerability Among Different Eutropin Formulations in Healthy Volunteers

Bioavailability, Safety and Tolerability Among Different Eutropin Formulations in Healthy Volunteers

Korea, Republic of
ARC Medical Devices Inc.

Completed

Discrete(TM) Safety Clinical Trial GLAD-01

Safety and Tolerability in Healthy Volunteers

Canada
Neurocrine Biosciences

Completed

Safety, Tolerability, and Pharmacokinetics of a Single Dose of NBI-98854 in Subjects With Mild,Moderate, or Severe Hepatic Insufficiency

Safety, Tolerability, and PK of NBI-98854 in Hepatically Impaired Subjects

United States
Zealand Pharma
Profil Institut für Stoffwechselforschung GmbH

Recruiting

A Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Safety and Tolerability

Germany
Galecto Biotech AB

Completed

A First in Human Study to Evaluate the Safety, Tolerability and PK of GB1211 in Healthy Subjects

Safety and Tolerability

United Kingdom
Getz Pharma
Primary Care Diabetes Association, Pakistan

Recruiting

Combination of Ertugliflozin And Sitagliptin Efficacy, Safety & Tolerability (CEASE Diabetes) Study (CEASE)

Efficacy | Tolerability | Safety

Pakistan
AstraZeneca

Completed

To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of Inhaled AZD7594

Pharmacokinetics | Safety | Pharmacodynamics of AZD7594

United Kingdom
AstraZeneca

Completed

To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses AZD8848 in Healthy Subjects

Healthy Subjects | Safety, | Tolerability,

United Kingdom
Celgene

Completed

A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult Subjects (AME/FE)

Safety and Pharmacokinetics in Healthy Volunteer Subjects

United States
AstraZeneca

Completed

Single Centre, Double-blind, Single and Multiple Ascending Inhaled Doses of AZD9819 in Healthy Subjects

Healthy Volunteers | Tolerability | Safety

United Kingdom
Beijing Center for Disease Control and Prevention
Beijing Minhai Biotechnology Co., Ltd

Completed

Safety and Immunogenicity of Freeze-dried Rabies Vaccine（MRC-5 Cell) in Chinese Humans

Safety, Immunogenicity
The Affiliated Hospital of Qingdao University

Enrolling by invitation

Bioequivalence Study of Ezetimibe Tablets Under Fed Conditions in Healthy Subjects

Pharmacokinetics | Safety

China
AstraZeneca

Completed

Investigating Safety, Tolerability and Efficacy of AZD5363 in Prostate Cancer. (PYRUS)

Metastatic Castrate-Resistant Prostate Cancer (mCRPC), | Efficacy, | Safety and Tolerability, | Pharmacokinetics, | Pharmacodynamics, | Tumour Response.

United Kingdom, United States
University of Minnesota
Paralyzed Veterans of America Research Foundation

Completed

Dose Escalation Study of Intravenous Baclofen in Healthy Adult Volunteers

Safety and Pharmacokinetics of Intravenous Baclofen

United States
University of Hohenheim
Universität Tübingen

Completed

Increasing the Oral Bioavailability of 6-prenylnaringenin by Micellar Solubilization

Safety of Native vs. Micellar 6-PN After Oral Intake | Pharmacokinetics of Native vs. Micellar 6-PN After Oral Intake | PBMC Activity After Native vs. Micellar 6-PN Oral Intake

Germany
University of British Columbia

Completed

Comparing 2L Bi-Pegyte to 4L PegLyte Regiments for Outpatient Colonic Preparation

Efficacy of Bowel Preparation | Ease of Bowel Preparation and Patient Tolerability

Canada
Butantan Institute
University of Sao Paulo; Insituto Adolfo Lutz; Centro de Referencia e Treinamento...

Completed

Evaluation of Pandemic Influenza A (H1N1) Vaccine in Chronic and or Immunocompromised Patients, Elderly and Pregnants

Immunocompromised Patients | Safety of Pandemic Influenza A (H1N1)Vaccine | Immunogenicity of Pandemic Influenza A (H1N1)Vaccine

Brazil
PT Bio Farma

Completed

Reactogenicity and Protectivity Following Measles- Rubella (MR) Routine Immunization in Indonesian Infants and Children

Safety Issues | Immunogenicity

Indonesia
UMN Pharma Inc.

Completed

A Study to Evaluate the Immune Response to the ASP7374 and Its Safety in Healthy Adult Volunteers

Healthy | Immunogenicity of ASP7374

Japan
PT Bio Farma

Completed

Safety and Immunogenicity of Vi-DT Typhoid Conjugate Vaccine in Indonesian Adults, Adolescents, Children and Infants

Safety Issues | Immunogenicity

Indonesia
PT Bio Farma

Completed

Comparison of Immunogenicity and Safety of DTP-HB-Hib (Bio Farma) With Pentabio® Vaccine Primed With Recombinant Hepatitis B

Safety | Immunogenicity

Indonesia
Geropharm

Completed

Pharmacokinetics, Safety and Efficacy Study of GP30341 (GEROPHARM, Russia) in Healthy Volunteers and Outpatients With COVID-19

Pharmacokinetics | Efficacy | Safety Issues

Russian Federation
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Oral Contraceptive Containing Ethinyl Estradiol and Norethindrone

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Ethinyl Estradiol and Norethindrone

United States
PT Bio Farma

Completed

Immunogenicity and Safety of Vi-DT (Diphtheria Toxoid) Typhoid Conjugate Vaccine (Phase III)

Safety Issues | Immunogenicity

Indonesia
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Warfarin in Healthy Male Subjects

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of S- and R-warfarin | Pharmacodynamics of Warfarin

United States
Pfizer

Completed

A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.

Pharmacokinetics | Safety | Phase 1 | Single Dose | Toleration

Belgium
Lee's Pharmaceutical Limited

Completed

A Study to Evaluate the Safety and Tolerability of Tecarfarin in Healthy Chinese Volunteers

Pharmacokinetic and Pharmacodynamic Profile of Tecarfarin

Hong Kong
Jazz Pharmaceuticals

Completed

Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex

Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19...

United Kingdom
Boston Children's Hospital

Terminated

Comparing Safety and Efficacy of Dexmedetomidine and Propofol

Safety and Efficacy of Sedation Medications

United States
Taipei Medical University WanFang Hospital

Unknown

VATS Block for Uniportal Video-assisted Thoracoscopic Surgery

Efficacy and Safety of VATS Block
Bon Secours Pediatric Dental Associates

Unknown

Safety and Efficacy of Intranasal Dexmedetomidine

Safety and Efficacy of Intranasal Dexmedetomidine

United States
International Partnership for Microbicides, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

Bleeding | Pharmacokinetics | Safety Issues

United States
Ankara City Hospital Bilkent

Unknown

Novel Bidirectional Peripheral Artery Cannula in Minimally Invasive Aortic Valve Surgery

Efficacy and Safety of Novel Bidirectional Cannula

Turkey
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
AstraZeneca

Completed

Assessment of Safety, Tolerability and Blood Concentrations of Single Doses of AZD3839 in Healthy Volunteers

Healthy Volunteers | Alzheimer's Disease | Tolerability | Safety | Blood Concentration

United Kingdom

Clinical Trials on Tolerability, Safety, Immunogenicity and Pharmacokinetic of JS005

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bahamas

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations