Clinical Trials on Toxicity

Total 692 results

Tufts University
United States Agency for International Development (USAID); Harvard School...

Completed

Maternal EED and Aflatoxin Birth Outcomes Study Uganda

Inflammatory Response | Birth Weight | Pregnancy Preterm | Aflatoxins Toxicity

Uganda
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Metabolomic and Epigenetic Profiling of Bodyfluids From Lung and Brain Cancer Receiving Radiation Therapy

Lung Cancer | Radiation Toxicity | Adult Brain Tumor

United States
Centre Francois Baclesse

Completed

G-CSF in Preventing Neutropenia in Patients With Solid Tumors Who Are Receiving Chemotherapy

Neutropenia | Unspecified Adult Solid Tumor, Protocol Specific | Chemotherapeutic Agent Toxicity

France
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer

Cervical Cancer | Endometrial Cancer | Radiation Toxicity | Perioperative/Postoperative Complications | Gastrointestinal Complications | Urinary Complications | Urinary Tract Toxicity

United States, Canada, Singapore, Hong Kong
Centre Leon Berard

Recruiting

Cicaderma Efficacy vs Standard Care of Sites in Preventing Radiodermatitis in Non-metastatic Breast Cancer Patients (CICA-RT)

Radiation Toxicity | Radiation Dermatitis | Breast Adenocarcinoma

France
University of Alabama at Birmingham

Completed

Pharmacogenomic Profiling of Pediatric Patients

Mental Disorders | Metabolism Medication Toxicity | Pediatric Disorder

United States
University of Sao Paulo General Hospital

Completed

Neurovascular Changes Induced by Chemotherapy

Breast Cancer | Chemotherapeutic Toxicity

Brazil
Federal University of Rio Grande do Sul
Hospital A.C. Camargo

Recruiting

Comparison of Prophylactic Photobiomodulation Protocols in Chemoinduced Oral Mucositis in Oncology Patients

Childhood Cancer | Chemotherapeutic Toxicity | Oral Mucositis

Brazil
University of Thessaly

Recruiting

Aminoglycoside Administration in Septic Patients (AMASEP)

Sepsis | Septic Shock | Renal Replacement Therapy | Aminoglycoside Toxicity

Greece
CNAO National Center of Oncological Hadrontherapy

Recruiting

Longitudinal Registry Including Patients Treated With Heavy Particles

Cancer | Radiation Toxicity | Oncology | Radiotherapy Side Effect | Radiation Exposure | Rare Disease

Italy
Sunnybrook Health Sciences Centre
Queen's University; The Leukemia and Lymphoma Society

Recruiting

Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications

Lymphoma | Chemotherapeutic Toxicity

Canada
François Lellouche

Unknown

Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery

Surgery | COPD Exacerbation | Abdominal Obesity | Oxygen Toxicity

Canada
Laval University

Unknown

Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During SARS-CoV-2 Pneumonia (COVID-19)

Pneumonia | Coronavirus | Oxygen Toxicity

Canada
NHS Greater Glasgow and Clyde
Pneumowave Ltd

Recruiting

ARM-ED: Advanced Respiratory Monitoring Events in Drug Toxicity (ARM-ED)

Respiratory Insufficiency | Overdose of Opiate | Sedative Overdose | Sedative Toxicity

United Kingdom
Fundación Centro Nacional de Investigaciones Cardiovasculares...
European Commission

Recruiting

REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs (RESILIENCE)

Lymphoma | Anthracycline-induced Cardiac Toxicity

Netherlands, Spain, Denmark, Germany, France, Portugal
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Treatment of Acute Lymphoblastic Leukemia in Children

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Indiana University
Indiana University Melvin and Bren Simon Cancer Center

Completed

Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors

Brain and Central Nervous System Tumors | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
University of Sao Paulo General Hospital
InCor Heart Institute; Hospital do Cancer, Sao Paulo

Suspended

Evaluation of Regional Anticoagulation With Citrate in Extended Hemodialysis

Hemodialysis Complication | Acute Kidney Injury | Anticoagulant Toxicity

Brazil
Johns Hopkins University

Completed

Impact of Exercise on Mitigating the Cardio-toxic Effects of Adriamycin Among Women Newly Diagnosed With Breast Cancer.

Breast Cancer Female | Adriamycin Toxicity

United States
Cardiocentro Ticino

Unknown

Anesthetic Neurotoxicity: the Association Between General Anesthesia and the Level of Plasma Neurofilament Light (ANESTOX-2019)

General Anesthetics Toxicity

Switzerland
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Capsaicin Lozenges in Treating Patients With Mucositis Caused by Radiation Therapy

Head and Neck Cancer | Radiation Toxicity

United States
UMC Utrecht
The Netherlands Cancer Institute

Completed

The Effect of Hyperbaric OxygeN Therapy on brEast Cancer Patients With Late Radiation toxicitY - UMBRELLA HONEY Trial (HONEY)

Breast Cancer | Radiation Toxicity

Netherlands
Carol Davila University of Medicine and Pharmacy
S.C. Sanador S.R.L

Active, not recruiting

Acute Effects of Intravenous Iron on Oxidative Stress and Endothelial Dysfunction in Non-dialysis CKD

Endothelial Dysfunction | Oxidative Stress | Renal Anemia | Iron Toxicity

Romania
University of Padova

Completed

Effects of Ketogenic Diet in Divers Breathing Enriched Air Nitrox

Overweight and Obesity | Oxygen Toxicity | Exertion; Excess
Queen Mary University of London

Completed

Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles

Testicular Germ Cell Tumor | Drug/Agent Toxicity by Tissue/Organ

United Kingdom
Ligand Pharmaceuticals

Completed

Dexamethasone Followed by Denileukin Diftitox in Treating Patients With Persistent or Recurrent T-Cell Lymphoma

Lymphoma | Drug/Agent Toxicity by Tissue/Organ

United States
Wellstat Therapeutics

Completed

Triacetyluridine and Fluorouracil Compared With Gemcitabine in Treating Patients With Unresectable Locally Advanced, or Metastatic Pancreatic Cancer

Pancreatic Cancer | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Washington University School of Medicine
American Academy of Clinical Toxicology

Not yet recruiting

Rivastigmine for Antimuscarinic Delirium (RIVA-AM)

Anticholinergic Toxicity

United States
Brigham and Women's Hospital

Recruiting

First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers

Cholera | Cholera Vaccine Toxicity

United States
Taipei Medical University WanFang Hospital
Asia University

Recruiting

Oligo-Fucoidan Decrease Lung Radiation Damage (FIRILI)

Radiation Toxicity

Taiwan
Kwang Dong Pharmaceutical co., ltd.

Completed

Phase I Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics of KD101 in Healthy Male Subjects

Drug Toxicity

Korea, Republic of
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Silymarin (Milk Thistle Extract) in Treating Patients With Acute Lymphoblastic Leukemia Who Are Receiving Chemotherapy

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
University of Turin, Italy

Recruiting

Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery

Postoperative Pain | Regional Anesthesia Morbidity | Local Anesthetic Toxicity

Italy
Duke University

Active, not recruiting

PaRTNer: Patient Reported Outcomes and Financial Toxicity in Head and Neck Cancer A Pilot, Survey Based Study (PaRTNer)

Head and Neck Cancer

United States
Rigshospitalet, Denmark
Danish Cancer Society

Completed

Electronic Patient Reporting of Side Effects to Chemotherapy: A Cluster Randomized Controlled Trial

Chemotherapeutic Toxicity | Cancer, Breast | Adverse Event | Patient Outcomes Assessments
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Unknown

Individualized Intraperitoneal and System Chemotherapy Versus System Chemotherapy as First-line Chemotherapy for AGC

Stomach Neoplasms | Chemotherapy Effect | Chemotherapeutic Toxicity

China
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Recruiting

Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC) (SREC22)

Nicotine Dependence | Cardiovascular Risk Factors | Tobacco Toxicity

United States
University Hospital Hradec Kralove

Recruiting

The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus

Brain Damage | Hydrocephalus | General Anesthetics Toxicity

Czechia
Pontificia Universidad Catolica de Chile

Unknown

PK/PD Levobupivacaine With and Without Epinephrine After Ultrasound Guided ESP Block

Surgery | Nerve Block | Anesthetic Toxicity | Anesthetics Complications | Bupivacaine Overdose

Chile
Amsterdam UMC, location VUmc

Terminated

Safety Study of Bevacizumab (Avastin) With Thoracic Radiation in Non-small Cell Cell Lung Cancer

Toxicity

Netherlands
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Growth Factor to Prevent Oral Mucositis in Patients With Hematologic Cancer

Lymphoma | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Radiation Toxicity | Oral Complications | Drug/Agent Toxicity by Tissue/Organ

United States
Azienda Ospedaliera Città della Salute e della...

Completed

Subclinical Cardio-toxicities Evaluation With Strain Rate Echocardiography After Chemotherapy and/or Mediastinal Radiotherapy in Patient With Lymphoma (Cardiocare)

Lymphoma, Non-Hodgkin | Hodgkin Lymphoma | Toxicity, Cardiac

Italy
Children's Hospital Los Angeles
National Cancer Institute (NCI)

Completed

N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma

Diarrhea | Neuroblastoma | Drug/Agent Toxicity by Tissue/Organ

United States
Paracelsus Medical University
Heinrich-Heine University, Duesseldorf; Poznan University of Medical Sciences; University Hospital of Ferrara and other collaborators

Completed

Intra-Operative Electron Boost and Hypofractionated Whole-Breast Irradiation During Breast-conserving Treatment (BCT) (HIOB)

Toxicity | Local Neoplasm Recurrence

Austria
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Studying the Performance of OCT C-scan in the Screening for Retinopathy Related to Synthetic Antimalarials (PERFOCTAPS)

Maculopathy | Toxicity, Drug

France
Anhui Medical University

Unknown

High-Dose,Pulsatile Erlotinib/Gefitinib for Advanced NSCLC Patients After Failure of Standard Dose EGFR-TKIs

Self Efficacy | Drug Toxicity

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Medical Checklists in the Emergency Department

Emergencies | Tricyclic Antidepressant Poisoning | Tricyclic Antidepressant Toxicity

Netherlands
Central Hospital, Nancy, France
PAPE Elise

Not yet recruiting

Peritoneal Diffusion and Efficacy of Antibiotic Therapy in Pediatric Peritonitis (DIFFUPERPED)

Appendicitis | Peritonitis | Children, Only | Antibiotic Toxicity
Washington University School of Medicine
National Cancer Institute (NCI)

Completed

Patient-Centered Intervention to Reduce Cancer Patients' Financial Toxicity

Gynecologic Cancer | Colorectal Cancer | Lung Cancer

United States
Association Tunisienne d'Etude & de Recherche sur...
Faculty of Medicine of Tunis; Rabta University Hospital

Completed

Vitamin D Supplementation in Intensive Care Unit Patients

Vitamin D Deficiency | Intensive Care Unit | Dietary Supplements | Vitamin D Toxicity

Clinical Trials on Toxicity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Sri Lanka

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations