Clinical Trials on Transplantation, Homologous

Total 2247 results

Jennifer E. Schwartz
Millennium Pharmaceuticals, Inc.

Completed

A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) Transplantation

Graft vs Host Disease | Peripheral Blood Stem Cell Transplantation | Transplantation, Homologous

United States
Idience Co., Ltd.

Active, not recruiting

Basket Trial of IDX-1197, a PARP Inhibitor, in Patients With HRR Mutated Solid Tumors (VASTUS) (VASTUS)

Solid Tumors | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation

Korea, Republic of
University of Wisconsin, Madison

Completed

Glutamine Popsicles in Bone Marrow Transplant (BMT)/Hematopoietic Stem Cell Transplant (HSCT) Patients

Bone Marrow Transplantation | Hematopoietic Stem Cell Transplantion

United States
National Center for Research Resources (NCRR)
Juvenile Diabetes Research Foundation

Unknown

hOKT3gamma1 (Ala-Ala) for the Prevention of Human Islet Allograft Failure

Islets of Langerhans Transplantation | Diabetes Mellitus, Insulin-Dependent | Diabetes Mellitus, Experimental | Transplantation, Homologous

United States
Georgetown University
Oregon Health and Science University; Tesaro, Inc.

Terminated

Niraparib Plus Carboplatin in Patients With Homologous Recombination Deficient Advanced Solid Tumor Malignancies

Homologous Recombination Deficiency | Solid Tumor, Adult

United States
Stanford University

Completed

Phase 2 Study of Autologous Followed by Nonmyeloablative Allogeneic Transplantation Using TLI & ATG

Multiple Myeloma | Blood and Marrow Transplant (BMT) | Transplantation, Autologous | Transplantation, Homologous

United States
West Cancer Center

Recruiting

Niraparib and Dostarlimab in HRD Solid Tumors (DIDO)

Homologous Recombination Deficient Solid Tumors

United States
Hamad Medical Corporation
Sidra Medical and Research Center; World Anti-Doping Agency; Anti-Doping Lab... and other collaborators

Unknown

Using DNA-Typing and Erythrocyte Microparticle Analysis to Detect Blood Doping (Transfusion)

Blood Disease | Blood Transfusion, Autologous | Blood Doping | Blood Transfusion, Homologous

Qatar
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate FK778 in Kidney Transplant Patients

Kidney Transplantation | Renal Transplantation | Transplantation, Kidney | Grafting, Kidney | Transplantation, Renal

Belgium, Germany, Spain, Sweden, Italy, Switzerland, United Kingdom, Austria, France, Poland, Czech Republic, Netherlands
Fudan University

Recruiting

Cisplatin to Patients With Pancreatic Cancer and Homologous Recombination Deficiency (PTCA199-6)

Pancreatic Adenocarcinoma | Homologous Recombination Deficiency

China
Astellas Pharma Europe Ltd.

Completed

A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Czechia, France, Italy, Poland, United Kingdom
The Hospital for Sick Children

Completed

Pharmacogenetic Trial of Tacrolimus After Pediatric Transplantation

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Canada
Astellas Pharma Europe Ltd.

Terminated

A Paediatric, Open, Follow up Study With Modigraf Examining Safety and Efficacy in de Novo Allograft Recipients (PROGRESSION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Astellas Pharma Europe Ltd.

Completed

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Spain, Australia, France, Germany, Canada, Italy, United Kingdom, Belgium, South Africa, Switzerland, Sweden, United States, Austria, Brazil, Czechia, Denmark, Finland, Hungary, Ireland, Mexico, Netherlands, New Zealand, Poland
Astellas Pharma Europe Ltd.

Completed

A Study to Determine Pharmacokinetics of Children Receiving Modigraf (Tacrolimus Granules) Following Solid Organ Transplantation (OPTION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Astellas Pharma Inc

Completed

Study to Compare the Pharmacokinetics of Tacrolimus in Adult Transplant Recipients Treated With Advagraf® or Prograf®

Heart Transplantation | Lung Transplantation | Pancreas (Including SPK) Transplantation

France, United Kingdom, Taiwan, Belgium, Italy, Austria
Emory University

Completed

Quality of Life in Pediatric Transplant Recipients

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Heart-Lung Transplantation

United States
Novartis

Completed

Conversion Trial From Mycophenolate Mofetil (MMF) to Enteric-coated Mycophenolate Sodium (EC-MPS) in Stable Transplanted Patients Suffering From Gastrointestinal (GI) Adverse Events While on Mycophenolate Mofetil Therapy (MMF) Therapy

Liver Transplantation | Kidney Transplantation

Switzerland
University of Wisconsin, Madison

Terminated

Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant

Liver Transplantation | Kidney Transplantation

United States
Nantes University Hospital

Unknown

A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids

Kidney Transplantation | Pancreas Transplantation

France
University Hospital, Gasthuisberg
Juvenile Diabetes Research Foundation; Fund for Scientific Research, Flanders...

Unknown

Insulin Secretory Capacity in Insulin-independent Pancreas-Kidney Recipients Compared to Controls

Kidney Transplantation | Pancreas Transplantation

Belgium
National Taiwan University Hospital

Unknown

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC

Recruiting

A Study of Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy

Metastatic Pancreatic Ductal Adenocarcinoma | Homologous Recombination Deficiency (HRD)

United States
Charite University, Berlin, Germany

Unknown

RM-493 Treatment Trial in Proopiomelanocortin (POMC) Deficient Patients

Homozygous or Compound Heterozygous POMC, LEPR or PCSK1 Gene Mutation

Germany
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Treg Cell Therapy in Liver and Kidney Transplantation - Preclinical Validation of Batches of Treg Cells Amplified in Vitro (PRE-TREG)

Liver Transplantation | Kidney Transplantation

France
Emory University

Recruiting

Immune Monitoring and Assay Development in Organ Transplant Recipients (IMP)

Organ Transplantation | Transplantation Immunology

United States
Astellas Pharma China, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
Astellas Pharma China, Inc.

Completed

A Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
University of Nebraska

Completed

Pre-operative Evaluation of Kidney & Pancreas Transplant Patients

Kidney Transplantation | Pancreas Transplantation

United States
Rennes University Hospital

Completed

Impact of P-gp, MRP2, ENT-1 and CNT3 on the Blood Concentration / Intra-PBMC Concentration of Tacrolimus (TRANS-TAC)

Liver Transplantation | Kidney Transplantation

France
Bristol-Myers Squibb

Completed

Pattern Of Use Of Belatacept In US Transplant Recipients

Kidney Transplantation: Transplantation, Kidney
Helsinki University Central Hospital
Tampere University Hospital

Completed

Immunogenicity of 13-valent Pneumococcal Conjugate Vaccine Compared to the Pneumococcal Polysaccharide Vaccine in Adult Kidney and Liver Transplant Patients (SOT13)

Liver Transplantation | Kidney Transplantation

Finland
National Taiwan University Hospital

Unknown

The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration

Liver Transplantation | Kidney Transplantation

Taiwan
Astellas Pharma Inc

Completed

A Study to Demonstrate Safety and Efficacy of Advagraf in Patients Undergoing Kidney or Liver Transplantation in India

Liver Transplantation | Kidney Transplantation

India
University of Manchester
Manchester University NHS Foundation Trust

Unknown

CEUS in Kidney and Pancreas Transplantation

Kidney Transplantation | Pancreas Transplantation

United Kingdom
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Organ Transplantation Rehabilitation: Effect of Bedside Exercise Device and Activity Reinforcement

Liver Transplantation | Heart Transplantation

Taiwan
University of Oslo School of Pharmacy

Completed

Intracellular and Renal/Myocardial Tissue Concentrations of Cyclosporine A (CsA) and Rejection Frequency Following Transplantation

Heart Transplantation | Renal Transplantation

Norway
Nantes University Hospital

Terminated

Protocol DIVAT-Uro

Kidney Transplantation | Pancreas-kidney Transplantation

France
Hospices Civils de Lyon

Completed

Bile Acids and Incretins in Pancreas Kidney Transplant Patients (ITABI)

Kidney Transplantation | Pancreas-kidney Transplantation

France
Novartis

Completed

Everolimus in a Cyclosporine Microemulsion-free Regimen Compared to a Low-dose Cyclosporine Microemulsion Regimen, in de Novo Kidney Transplant Patients (CERTES02)

Organ Transplantation, Renal Transplantation
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation

Terminated

Optimization of NULOJIX® Usage As A Means of Avoiding CNI and Steroids in Renal Transplantation

Kidney Transplantation | Renal Transplantation

United States
National Taiwan University Hospital

Unknown

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Washington University School of Medicine
National Marrow Donor Program; Predictive BioDiagnostics, LLC

Completed

Study for the Evaluation of a GVHD Negative Outcome Score (GNOS) in Matched Unrelated or Haploidentical Hematopoietic Stem Cell Transplant

Hematopoietic Stem Cell Transplantation | Stem Cell Transplantation, Hematopoietic | Transplantation, Hematopoietic Stem Cell

United States
University of North Carolina, Chapel Hill
Mallinckrodt

Withdrawn

Acthar for Treatment of Post-transplant FSGS

Kidney Transplantation | Renal Transplantation | FSGS

United States
Bristol-Myers Squibb

Completed

Study Comparing the Safety and Efficacy of Belatacept With That of Cyclosporine in Patients With a Transplanted Kidney

Kidney Transplantation | Graft Rejection | Renal Transplantation

United States
National Center for Complementary and Integrative...
National Cancer Institute (NCI)

Completed

The Effects of Music Therapy-Based Stress Reduction on Bone Marrow Transplant Recipients

Stem Cell Transplantation | Bone Marrow Transplantation

United States
Medical College of Wisconsin

Terminated

Quality of Life in Pediatric Transplant Patients

Liver Transplantation | Kidney Transplantation | Heart Transplantation

United States
Hospital Israelita Albert Einstein

Recruiting

Impact of Yoga and Gentle Massage Practices on Symptom Management in Patients Undergoing HSCT (Yoga)

Bone Marrow Transplantation | Hematopoietic Stem Cell Transplantation

Brazil
National Institute of Allergy and Infectious Diseases...
PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Active, not recruiting

Tolerance by Engaging Antigen During Cellular Homeostasis (TEACH)

Kidney Transplantation | Renal Transplantation | Renal Transplant Recipient

United States

Clinical Trials on Transplantation, Homologous

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