Clinical Trials on Tuberculosis, Pulmonary in United States

Total 3173 results

Universiteit Antwerpen
Aurum Institute; University of Stellenbosch; University of the Free State; Free...

Recruiting

Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment Trial (SMARTT)

Drug-resistant Tuberculosis | Rifampicin Resistant Tuberculosis | Pulmonary Tuberculoses | Multidrug Resistant Tuberculosis

South Africa
National Institute of Allergy and Infectious Diseases...

Terminated

Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in Mali

Tuberculosis, Pulmonary | Mycobacterium Tuberculous | Antitubercular Agents | Tuberculosis, Mulutidrug-Resistant | Extensively Drug-Resistant | Extensibely Drug-Resistant Tuberculosis

United States, Mali
Global Alliance for TB Drug Development

Completed

Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
Global Alliance for TB Drug Development

Completed

A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Interferon Gamma for Drug Resistant Tuberculosis

Pneumonia | Pulmonary Tuberculosis

United States
Centers for Disease Control and Prevention

Completed

High Dose Rifapentine Pharmacokinetics, Tolerability and Safety Dosage Rifapentine for Treatment of Tuberculosis (TBTC-29PK)

Smear Positive, Pan-sensitive, Pulmonary Tuberculosis

United States, South Africa, Uganda
IDRI
Aeras; Paul G. Allen Family Foundation

Completed

Phase 1 ID93 + GLA-SE Vaccine Trial in Healthy Adult Volunteers

Pulmonary Tuberculosis

United States
Cepheid
Centers for Disease Control and Prevention; AIDS Clinical Trials Group

Completed

Evaluation of Xpert MTB/RIF Assay for the Rapid Identification of TB and TB Rifampin Resistance in Pulmonary Tuberculosis Suspects

Tuberculosis

United States
Landon Pediatric Foundation

Completed

Tuberculosis Volatile Organic Compounds (TBVOC)

Pulmonary Tuberculosis

United States
Janssen Research & Development, LLC

Completed

A Prospective Patient Registry of Patients Exposed to Bedaquiline

Pulmonary Multi-drug Resistant Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary Tuberculosis

Tuberculosis

United States, Brazil
National Institute of Allergy and Infectious Diseases...

Completed

A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.

HIV Infections | Tuberculosis

United States
NYU Langone Health

Completed

Evaluation of the Practice of Three Morning Sputa on Separate Days for Diagnosis of Mtb

Pulmonary TB

United States
Access to Advanced Health Institute (AAHI)
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes...

Completed

Phase 1 Clinical Trial of Single-Vial ID93 + GLA-SE in Healthy Adults

Pulmonary TB

United States
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

TBTC Study 22: Efficacy of Once-Weekly Rifapentine and Isoniazid in Treatment of Tuberculosis

Pulmonary Tuberculosis

United States, Canada
National Institute of Allergy and Infectious Diseases...

Completed

A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacin

HIV Infections | Tuberculosis

United States
Centers for Disease Control and Prevention
Sanofi

Completed

TBTC Study 29: Rifapentine During Intensive Phase Tuberculosis (TB) Treatment

Pulmonary Tuberculosis

Uganda, United States, South Africa, Brazil, Canada, Spain
BioMérieux

Completed

Performance Evaluation of the VIDAS TB-IGRA Assay.

Active Tuberculosis | Latent Tuberculosis Infection | Non-Tuberculous Mycobacterial (NTM) Pneumonia

United States, France, United Kingdom, India, Brazil, Georgia, Italy, Mexico, South Africa
Prof Gerhard Walzl
London School of Hygiene and Tropical Medicine; Makerere University; Leiden University... and other collaborators

Completed

Evaluation of Host Biomarker-based Point-of-care Tests for Targeted Screening for Active TB (ScreenTB)

Pulmonary Tuberculosis

United Kingdom, Uganda, Ethiopia, Gambia, Germany, Namibia, Netherlands, South Africa
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Trial to Evaluate OPC 67683 in Participants With Pulmonary Sputum Culture-positive, Multidrug-resistant Tuberculosis (TB)

Tuberculosis, Pulmonary | Extensively Drug-Resistant Tuberculosis | Tuberculosis, Multidrug Resistant

Korea, Republic of, China, United States, Egypt, Estonia, Japan, Latvia, Peru, Philippines
Centers for Disease Control and Prevention
Tuberculosis Trials Consortium

Recruiting

Short-course Regimens for the Treatment of Pulmonary Tuberculosis (CRUSH-TB)

Tuberculosis, Pulmonary | Tuberculosis Infection

Canada, United States, Haiti, South Africa, Uganda, Vietnam
Global Alliance for TB Drug Development

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid

Tuberculosis | Tuberculosis, Pulmonary

United States
Andrew Dinardo
Bristol-Myers Squibb

Withdrawn

Azacytidine During Anti-tuberculosis Therapy (AZA)

Tuberculosis, Pulmonary

United States
Johns Hopkins University
Sanofi; Centers for Disease Control and Prevention

Completed

Pharmacokinetics, Safety and Tolerability of Escalating Rifapentine Doses in Healthy Volunteers (TBTC S29B)

Tuberculosis | Tuberculosis, Pulmonary

United States
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary

United States
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, PK, and PK Interactions of TBA-7371

Tuberculosis | Tuberculosis, Pulmonary

United States
Global Alliance for TB Drug Development

Completed

Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects

Tuberculosis | Tuberculosis, Pulmonary

United States
Barts & The London NHS Trust
British Lung Foundation

Completed

Trial of Adjunctive Vitamin D in Tuberculosis Treatment

Tuberculosis, Pulmonary

United Kingdom
Obafemi Awolowo University Teaching Hospital
University Hospital Birmingham NHS Foundation Trust; Cures Within Reach

Completed

Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) (ATORTUB)

Tuberculosis | Tuberculosis, Pulmonary

United Kingdom, Nigeria
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung

Healthy | Latent Tuberculosis Infection (LTBI)

United States
Midwest Pulmonary and Critical Care
Genentech, Inc.

Completed

Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas (CPE)

Pleural Effusion Associated With Pulmonary Infection | Bacterial Pleural Effusion Other Than Tuberculosis

United States
Boston Medical Center
Jawaharlal Institute of Postgraduate Medical Education & Research

Enrolling by invitation

Tuberculosis - Learning the Effect of Parasites and Reinforcing Diets (TB-LEOPARD)

Malnutrition | Tuberculosis, Pulmonary | Helminthiasis

United States, India
National Institute of Allergy and Infectious Diseases...

Recruiting

Training Protocol on the Natural History of Tuberculosis

Mycobacterium Infections | Latent Tuberculosis | Tuberculosis | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

United States
Victor Tapson, MD
Bristol-Myers Squibb

Terminated

Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism (SAFE-LYSE)

Pulmonary Embolism | Right Ventricular Dysfunction | Right Ventricular Failure | Pulmonary Embolism With Acute Cor Pulmonale | Pulmonary Embolism With Pulmonary Infarction | Pulmonary Embolism Subacute Massive

United States
Centers for Disease Control and Prevention

Completed

TBTC Study 27: Moxifloxacin vs Ethambutol for TB Treatment

Tuberculosis, Pulmonary

Uganda, United States, Canada, South Africa
JHP Pharmaceuticals LLC
Syneos Health

Unknown

Equivalence Study of Specificity of PPD (03)

Tuberculosis Infection

United States
QIAGEN Gaithersburg, Inc

Completed

Evaluation of the 4th Generation QuantiFERON-TB Test (QFT-Plus) for the Detection of Tuberculosis Infection

Tuberculosis

United States
JHP Pharmaceuticals LLC
Syneos Health

Unknown

Dose Study of Tuberculin Purified Protein Derivative (JHP/Dose)

Tuberculosis Infection

United States
University of California, San Diego

Completed

VDOT for Monitoring Adherence to LTBI Treatment (VMALT)

Tuberculosis | Latent Tuberculosis Infection

United States
Global Alliance for TB Drug Development

Completed

A Study in Two Panels of Healthy Adult Participants to Assess Single-Dose Immediate-Release and Single-Dose Dispersible Formulations of Pretomanid

Multi-drug Resistant Tuberculosis

United States
Atlanta VA Medical Center

Withdrawn

Vitamin D in Active Tuberculosis (TB) Study

Tuberculosis

United States
Centers for Disease Control and Prevention
Columbia University; New York City Department of Health and Mental Hygiene

Completed

An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment

Tuberculosis | Adherence, Medication | Drug-resistant Tuberculosis | Adherence, Patient

United States
Northwell Health
Staten Island University Hospital

Completed

Is Tuberculin Skin Testing Effective in Screening for Latent Tuberculosis (TB) in Elderly Residents of Nursing Homes?

Tuberculosis

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted With Cobicistat in Healthy Volunteers

HIV Infected Population With Latent Tuberculosis

United States
University of California, Irvine
University of California, Los Angeles; National Institute on Minority Health...

Completed

Nurse-Led Community Health Worker Adherence Model in 3HP Delivery Among Homeless Adults at Risk for TB Infection and HIV (3HP-LTBI)

Latent Tuberculosis Infection

United States
M.D. Anderson Cancer Center

Completed

Latent Tuberculosis Infection in Cancer Patients

Advanced Cancer

United States
Henry M. Jackson Foundation for the Advancement...
Infectious Diseases Clinical Research Program

Completed

Screening for Latent Tuberculosis Infection (LTBI) in US Army Recruits (LTBI)

Latent Tuberculosis Infection

United States
Northwell Health

Completed

Is Tuberculin Skin Testing Effective in Screening for Latent Tuberculosis in Patients With HIV?

HIV Infections | Latent Tuberculosis

United States
GlaxoSmithKline
Corixa Corporation

Completed

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine Given to PPD-Negative Adults

Tuberculosis (TB)

United States
Kaiser Permanente

Active, not recruiting

Brief Educational Video for Patients Prescribed LTBI Treatment

Latent Tuberculosis

United States

Clinical Trials on Tuberculosis, Pulmonary in United States

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