Clinical Trials on Tumor Microenvironment

Total 16923 results

University of Pennsylvania

Completed

Two-Part Study to Evaluate the Safety and Efficacy of Image Guided Surgery Using Indocyanine Green for Intramolecular Imaging of Nervous System Tumors Compared to Standard of Care, (TumorGlow) (TumorGlow(TM))

Brain Tumor, Recurrent | Brain Tumor, Primary
Regeneron Pharmaceuticals
Pacific Pediatric Neuro-Oncology Consortium

Terminated

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

High Grade Glioma | Diffuse Intrinsic Pontine Glioma | Relapsed Solid Tumor | Refractory Solid Tumor | Relapsed Central Nervous System Tumor | Refractory Central Nervous System Tumor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

Brain Tumor | Central Nervous System Tumor

United States
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Bevacizumab in Treating Patients With Recurrent Sex Cord-Stromal Tumors of the Ovary

Malignant Ovarian Epithelial Tumor | Ovarian Gynandroblastoma | Ovarian Sertoli-Leydig Cell Tumor | Ovarian Sex Cord Tumor With Annular Tubules | Ovarian Steroid Cell Tumor | Ovarian Granulosa Cell Tumor | Ovarian Sex Cord-Stromal Tumor | Ovarian Sex Cord-Stromal Tumor of Mixed or Unclassified Cell...

United States
Peking Union Medical College Hospital

Recruiting

18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor

Neuroendocrine Tumor | Neuroblastoma | Pheochromocytoma | Paraganglioma

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer

Sarcoma | Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Psychosocial Effects of Cancer and Its Treatment | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States, Puerto Rico, Canada, Switzerland
University of Zurich

Unknown

Epidemiology and Outcome of Solitary Fibrous Tumors of the Pleura.

Solitary Fibrous Tumors of the Pleura

Switzerland
University of Wisconsin, Madison

Not yet recruiting

Using Novel Imaging to More Safely Treat Neuroendocrine Tumors

Neuroendocrine Tumors | Somatostatin Receptor-positive Neuroendocrine Tumor

United States
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Longitudinal Study of Biomarkers

Central Nervous System Tumor

United States
Centre Leon Berard

Completed

A Multicenter Study to Evaluate a Risk-adapted Strategy for Treatment of Extra Cranial Non Seminomateous Malignant Germ Cell Tumour in Children and Adolescent

Extra Cranial Non Seminomateous Malignant Germ Cell Tumour

France
Andrei Iagaru

No longer available

68Ga DOTA-TATE PET/CT in Somatostatin Receptor Positive Tumors

Carcinoid Tumors | Islet Cell (Pancreatic NET) | Other Neuroendocrine Tumors

United States
Vanderbilt-Ingram Cancer Center

Recruiting

Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

Metastatic Digestive System Neuroendocrine Neoplasm | Metastatic Malignant Neoplasm in the Liver | Pancreatic Neuroendocrine Tumor G1 | Pancreatic Neuroendocrine Tumor G2 | Digestive System Neuroendocrine Tumor G1 | Digestive System Neuroendocrine Tumor G2

United States
Plexxikon

Terminated

A Study of PLX73086 in Advanced Solid Tumors and Locally Advanced or Refractory Tenosynovial Giant Cell Tumor

Solid Tumors | Tenosynovial Giant Cell Tumor | Synovitis, Pigmented Villonodular

United States
Sun Yat-sen University

Recruiting

Liposomal Bupivacaine vs Ropivacaine for TAPBs

Postoperative Analgesia | Ropivacaine | Liposomal Bupivacaine | Abdominal Tumor

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Radiation Therapy in Treating Patients With Ewing's Sarcoma, Peripheral Primitive Neuroectodermal Tumor, or Rhabdomyosarcoma

Sarcoma

United States
National Cancer Institute (NCI)

Completed

Everolimus and Octreotide Acetate With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumors That Cannot Be Removed by Surgery

Locally Advanced Pancreatic Neuroendocrine Tumor | Pancreatic Neuroendocrine Tumor G1 | Pancreatic Neuroendocrine Tumor G2 | Pancreatic Vipoma | Pancreatic Gastrinoma | Advanced Pancreatic Neuroendocrine Tumor

United States, Canada
Sue O'Dorisio
University of Iowa

Completed

Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors

Neuroendocrine Tumors | Medulloblastoma | Neuroblastoma | Carcinoid Tumors

United States
Novartis Pharmaceuticals

Active, not recruiting

LUTATHERA Injection General Use Result Survey

Somatostatin Receptor-positive Neuroendocrine Tumor

Japan
IRCCS San Raffaele

Recruiting

Asymptomatic Small Pancreatic Endocrine Neoplasms. (ASPEN)

Non Functioning Pancreatic Endocrine Tumor

Italy
Assistance Publique - Hôpitaux de Paris
Institut National de Recherche en Informatique et en Automatique

Unknown

Liver Resection Modeling (LRM)

Cirrhosis | Benign Liver Tumor | Malignant Tumor Liver
Memorial Sloan Kettering Cancer Center
M.D. Anderson Cancer Center; Milton S. Hershey Medical Center; Stanford University and other collaborators

Active, not recruiting

Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

Lymphoma | Leukemia | Solid Tumor | Central Nervous System Tumor

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy in Treating Young Patients With Gliomas

Brain Tumor | Central Nervous System Tumor

United States, Canada, Australia, Puerto Rico, Switzerland, New Zealand
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood

Neuroectodermal Tumors, Primitive | Medulloblastoma | Brain Tumors

France
Wuxi People's Hospital

Recruiting

Clinical Study on the Treatment of Advanced Recurrent Tumors With Anticancer Mouse Characteristic Human Neutrophils

Advanced Cancer | Solid Tumor, Adult

China
Institut du Cancer de Montpellier - Val d'Aurelle

Recruiting

Creation of a Clinical Database on Primary Nervous System Tumors (BDD-NO)

Nervous System Tumor

France
AO Innovation Translation Center
AO Foundation, AO Spine

Recruiting

Metastatic Tumor Research and Outcomes Network (MTRON)

Metastatic Spine Tumor

United States, Canada, Hungary, Australia, Germany, Italy, Japan, Netherlands, Singapore, Switzerland
Massachusetts General Hospital
National Cancer Institute (NCI)

Completed

Effect of High Doses of Radiation on Bone Structure and Metabolism

Malignant Bone Tumors

United States
Bavarian Nordic

Completed

A Phase 1 Open Label Trial of Intravenous Administration of MVA-BN-Brachyury Vaccine in Patients With Advanced Cancer

Solid Metastatic Tumor

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors

Carcinoid Tumor | Functioning Pancreatic Neuroendocrine Tumor | Intermediate Grade Lung Neuroendocrine Neoplasm | Locally Advanced Pancreatic Neuroendocrine Tumor | Locally Advanced Unresectable Digestive System Neuroendocrine Neoplasm | Low Grade Lung Neuroendocrine Neoplasm | Metastatic Digestive... and other conditions

United States
National Taiwan University Hospital

Recruiting

ERAS Anesthetic Care for Metastatic Spine Cancer Resection

Metastatic Bone Tumor

Taiwan
Genentech, Inc.

Completed

A Study of the Safety and Pharmacokinetics (PK) of MEHD7945A in Participants With Locally Advanced or Metastatic Epithelial Tumors

Epithelial Tumors, Malignant

Spain, United States
Children's Healthcare of Atlanta

Terminated

Rare Tumor Case Review

Tumors | Intrapericardial Teratoma Tumor

United States
Fudan University
Qilu Hospital of Shandong University; First Affiliated Hospital Xi'an Jiaotong... and other collaborators

Recruiting

Long-term Prognosis for Non-functional Neuroendocrine Tumors of the Pancreatic Body and Tail ≤ 3cm

Non Functioning Pancreatic Endocrine Tumor

China
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumor | Metastatic Malignant Neoplasm in the Liver | Stage I Pancreatic Neuroendocrine Tumor AJCC v8 | Stage II Pancreatic Neuroendocrine Tumor AJCC v8 | Stage III Pancreatic Neuroendocrine Tumor AJCC v8

United States
Grupo Espanol de Investigacion en Sarcomas

Completed

Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma (ABRADES)

Sarcoma | Sarcoma, Ewing | Desmoid | Tumor, Desmoplastic Small Round Cell, Adult | Tumor, Desmoplastic Small Round Cell, Childhood

Spain
National Cancer Institute, Naples

Recruiting

A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus, Sunitinib or PRRT (CABOTEM) (CABOTEM)

Lung Neuroendocrine Neoplasm | GEP Neuroendocrine Tumor

Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Prophylactic Cholecystectomy is Not Mandatory in Patients Candidate to the Resection for Small Intestine Neuroendocrine Neoplasms: a Propensity Score-matched and Cost-minimization Analysis

Surgery | Neuroendocrine Tumors | Gut Tumor
JS InnoPharm, LLC

Recruiting

ERK Inhibitor JSI-1187 in Advanced Solid Tumors

Melanoma | NSCLC | Solid Tumor

China
Blaze Bioscience Inc.
Pacific Pediatric Neuro-Oncology Consortium

Completed

Study of Tozuleristide and the Canvas Imaging System in Pediatric Subjects With CNS Tumors Undergoing Surgery

Pediatric Central Nervous System Tumor

United States
New York Medical College

Terminated

ODSH + ICE Chemotherapy in Pediatric Solid Tumors

Sarcoma | Neuroblastoma | Wilms' Tumor | Refractory Solid Tumor | Recurrent Solid Tumor

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Avutometinib for People With Solid Tumor Cancers

Solid Tumor | Neuroblastoma | Solid Tumor, Adult | Primary Brain Tumor | Solid Carcinoma | Low-grade Glioma | Central Nervous System Tumor | Refractory Cancer | CNS Tumor, Adult | CNS Tumors | NF1 | Plexiform Neurofibroma | CNS Tumor, Childhood | Optic Pathway Gliomas | MAP Kinase Family Gene Mutation

United States
Nantes University Hospital

Terminated

Study of the Effect of Zoledronate on Local Recurrence After Surgical Treatment of Giant Cell Tumors of Bone Zométa (Zometa)

Giant Cell Tumors of Bone

France
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; American...

Active, not recruiting

Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

Glioblastoma Multiforme | Medulloblastoma | Low-Grade Astrocytoma, Nos | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Pineoblastoma | Supratentorial Primitive Neuroectodermal Tumor | Atypical Teratoid/Rhabdoid Tumor | Choroid Plexus Carcinoma | High-grade Astrocytoma NOS | CNS... and other conditions

United States
British Columbia Cancer Agency

Withdrawn

177Lu-DOTATOC for the Treatment of Patients With Somatostatin Receptor Positive NETs

Neuroendocrine Tumors | Carcinoid Tumor | Gastrinoma | Insulinoma | Vipoma | Gastroenteropancreatic Neuroendocrine Tumor | Pulmonary Carcinoid Tumor

Canada
University of California, San Francisco
Gilead Sciences

Suspended

Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors (PNOC025)

Brain Cancer | Malignant Brain Tumor | Brain Tumor Adult | Recurrent Brain Tumor | Progressive Malignant Brain Tumor | Brain Tumor, Pediatric

United States
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors or Other Solid Tumors

Solid Tumor | Locally Advanced or Metastatic Digestive Tract Tumors

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Evaluating Dactinomycin and Vincristine in Young Patients With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Ewing Sarcoma of Bone | Ewing Sarcoma | Childhood Acute Lymphoblastic Leukemia | Wilms Tumor and Other Childhood Kidney Tumors | Childhood Rhabdomyosarcoma | Childhood Soft Tissue Sarcoma | Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor...

United States, Australia, Canada
Second Affiliated Hospital, School of Medicine,...
Zhejiang University; The First Affiliated Hospital of the Fourth Military Medical...

Completed

Related Studies of Imaging Features and Prognosis Between Pancreatic Neuroendocrine Tumors and Pancreatic Cancer

Carcinoma, Pancreatic | CT | Neuroendocrine Tumor of Pancreas

China
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors

Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States

Clinical Trials on Tumor Microenvironment

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