Clinical Trials on Tumors, Central Nervous System in United States

Total 57245 results

Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Istari Oncology, Inc.
Duke University; Solving Kids' Cancer; The Andrew McDonough B+ Foundation

Completed

Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

Glioblastoma | Malignant Glioma | Gliosarcoma | Ependymoma | Medulloblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Atypical Teratoid/Rhabdoid Tumor of Brain | Pleomorphic Xanthoastrocytoma of Brain | Embryonal Tumor of Brain

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

Sarcoma | Neuroblastoma | Brain Tumors | Central Nervous System Tumors

United States, Canada, Australia
InSightec

Recruiting

A Feasibility Safety Study of Benign Centrally-Located Intracranial Tumors in Pediatric and Young Adult Subjects

Benign Centrally-Located Intracranial Tumors

United States
Herbert Irving Comprehensive Cancer Center

Unknown

Temozolomide in Treating Patients With Recurrent or Progressive Malignant Glioma

Brain and Central Nervous System Tumors

United States
Memorial Sloan Kettering Cancer Center
Columbia University

Completed

[18F] FACBC and [18F] FLT PET Imaging in Central Nervous System Tumors

Brain Cancer | Gliomas

United States
Dana-Farber Cancer Institute

Active, not recruiting

Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy

Pediatric Cancer | Skin Inflammation | CNS Tumor, Childhood

United States
Virginia Commonwealth University

Completed

CBT for Insomnia in Primary Brain Tumor Patients

Primary Brain Tumor | PBT

United States
University of California, San Francisco
Agenus Inc.

Completed

HSPPC-96 Vaccine With Temozolomide in Patients With Newly Diagnosed GBM (HeatShock)

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Terminated

Enrollment on the Childhood Cancer Research Network (CCRN) of the Children s Oncology Group

Sarcoma | Leukemia | Pediatric Cancer | Brain Tumors

United States
Duke University
Novartis; National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma

Osteoporosis | Brain Tumors | Central Nervous System(CNS)Malignancies

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Novartis Pharmaceuticals

Completed

AEE788 and Everolimus in Treating Patients With Recurrent or Relapsed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Children's Hospital of Philadelphia
Emory University; Stanford University

Terminated

Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma

Medulloblastoma | Brain Tumors | Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors

Glioblastoma | Gliosarcoma | Medulloblastoma | Anaplastic Astrocytoma | Choroid Plexus Neoplasms | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Neuroectodermal Tumor, Primitive | Brainstem Tumors | Teratoid Tumor, Atypical

United States
M.D. Anderson Cancer Center

Recruiting

Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Rhabdomyosarcoma | Refractory Neuroblastoma | Refractory Rhabdomyosarcoma | Desmoplastic Small Round Cell Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor | Ewing Sarcoma/Peripheral... and other conditions

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors | Carcinoma of Unknown Primary

United States
Duke University
National Cancer Institute (NCI)

Completed

Gliadel Wafer and O6-Benzylguanine in Treating Patients With Recurrent Glioblastoma Multiforme

Recurrent Adult Brain Tumor

United States
Tufts Medical Center

Terminated

Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors

Brain Cancer | Choroid Plexus Tumors

United States, Hungary, New Zealand, Germany
St. Jude Children's Research Hospital
University of Miami

Completed

Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and Lymphomas

Neuroblastoma | Central Nervous System Tumors | Wilms Tumor | Lymphomas

United States
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Completed

Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

High-dose ICE With Amifostine

Sarcoma | Kidney Cancer | Testicular Germ Cell Tumor | Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Bladder Cancer | Extragonadal Germ Cell Tumor | Carcinoma of Unknown Primary

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

Alanosine in Treating Patients With Progressive or Recurrent Malignant Gliomas

Brain and Central Nervous System Tumors

United States
Eli Lilly and Company
Children's Oncology Group

Completed

A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

Recurrent Tumor | Pediatric Solid Tumor | Refractory Tumor | CNS Malignancies

United States
University of South Florida
National Cancer Institute (NCI)

Completed

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

Fatigue | Brain and Central Nervous System Tumors | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
Dartmouth-Hitchcock Medical Center
National Cancer Institute (NCI)

Terminated

Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma

Brain Tumors | Central Nervous System Tumors | Leptomeningeal Metastases

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; American...

Active, not recruiting

Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

Glioblastoma Multiforme | Medulloblastoma | Low-Grade Astrocytoma, Nos | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Pineoblastoma | Supratentorial Primitive Neuroectodermal Tumor | Atypical Teratoid/Rhabdoid Tumor | Choroid Plexus Carcinoma | High-grade Astrocytoma NOS | CNS... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma

Brain and Central Nervous System Tumors

United States
Neurocrine Biosciences

Completed

NBI-3001 Followed by Surgery in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy

Thrombocytopenia | Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); PTC Therapeutics

Completed

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Brain and Central Nervous System Tumors

United States
St. Jude Children's Research Hospital
Duke University; Rady Children's Hospital, San Diego

Completed

Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma

Brain and Central Nervous System Tumors

United States
St. Jude Children's Research Hospital

Completed

DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma

Brain Tumors | Central Nervous System Tumors

United States
Duke University
Merck Sharp & Dohme LLC; Genentech, Inc.

Completed

Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

Malignant Glioma | Recurrent Glioblastoma Multiforme | Adult Brain Tumor

United States
University of Texas Southwestern Medical Center

Active, not recruiting

Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6

Glioblastoma | Brain Tumor | GBM | Brain Tumor, Recurrent

United States
Wake Forest University Health Sciences

Recruiting

Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab

Cancer | Epidural Spinal Tumors

United States
Yale University
National Cancer Institute (NCI)

Terminated

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Kidney Cancer | Head and Neck Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Intraocular Melanoma | Melanoma (Skin) | Pheochromocytoma | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome | Neuroendocrine Carcinoma of the Skin | Childhood Langerhans Cell Histiocytosis

United States
Massachusetts General Hospital
Conquer Cancer Foundation

Completed

Psychological Intervention For Brain Tumor Caregivers

Anxiety | Caregiver Burden | Malignant Glioma | Malignant Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Informed Consent in Pediatric Cancer Trials

Leukemia | Osteosarcoma | Neuroblastoma | Brain Tumors | Ewing's Sarcoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); BerGenBio ASA

Terminated

AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery

Brain and Central Nervous System Tumors

United States
NYU Langone Health

Completed

Study of Peptide Vaccination With Tumor Associated Antigens Mixed With Montanide in Patients With CNS Tumors

Tumors, Central Nervous System

United States
Acrotech Biopharma Inc.
National Cancer Institute (NCI)

Completed

To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Sarcoma | Lymphoma | Leukemia | Neuroblastoma | Brain Tumors | Wilms Tumor

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI); Children's Hospital of Michigan

Terminated

Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Osteosarcoma | Neuroblastoma | Retinoblastoma | Recurrent/Refractory Childhood Hodgkin Lymphoma | Wilms Tumor and Other Childhood Kidney Tumors | Childhood Choroid Plexus Tumor | Childhood Soft Tissue Sarcoma | Childhood Medulloblastoma | Childhood... and other conditions

United States
University of South Florida
National Cancer Institute (NCI)

Completed

Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy (SCUSF1202)

Unspecified Childhood Solid Tumor, Protocol Specific | Chemotherapy-induced Nausea and Vomiting | Central Nervous System Tumor, Pediatric

United States, Canada
Edward Ziga

Terminated

Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors

Glioma | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | High Grade Glioma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Jazz Pharmaceuticals

Completed

Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma

Brain and Central Nervous System Tumors

United States
Chimerix
National Institutes of Health (NIH)

Recruiting

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Glioblastoma | Neuroectodermal Tumors | Neuroectodermal Tumors, Primitive | Central Nervous System Neoplasms | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Pleomorphic Xanthoastrocytoma | Pleomorphic Xanthoastrocytoma | Oligodendroglioma | Choroid Plexus Neoplasms | Diffuse Astrocytoma | Anaplastic... and other conditions

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors

Central Nervous System Tumors

Korea, Republic of, United States, Canada, Germany, France

Clinical Trials on Tumors, Central Nervous System in United States

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Turkmenistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations