Clinical Trials on Underdosing of Local Anesthetics

Total 248 results

TRB Chemedica AG

Completed

Safety and Efficacy Study of HYTOP® in the Treatment of Focal Chondral Defects.

Focal Chondral Defect in Femoro-tibial Compartment of the Knee Joint

Germany
Hospital Universitari Vall d'Hebron Research Institute

Completed

Predisection Risk Factors for Vocal Cord Palsy After Total Thyroid Surgery

Recurrent Laryngeal Nerve Palsy | Risk Factors of Vocal Cord Palsy | Neuromonitoring in Thyroid Surgery
University Hospital, Strasbourg, France

Unknown

Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia (SPREAD)

Focal Epilepsy | Refractory Epilepsy | Focal Cortical Dysplasia

France
İpek Dokurel

Active, not recruiting

Does Levetiracetam and Carbamazepine Impact the Autonomic Activity of Children With Self-limiting Focal Epilepsy? (levcbz)

Epilepsy; Syndrome, Seizures of Localized Onset

Turkey
King's College Hospital NHS Trust
King's College London; Danish Epilepsy Centre

Recruiting

Mos-FED (Mosaicism in Focal Epilepsy Cortical Dysplasia Tissue) (MosFED)

Epilepsy | Focal Cortical Dysplasia

United Kingdom
Conrad Arnfinn Bjørshol

Completed

Postoperative Pain After Caesarian Section

Pain, Postoperative | Consumption | Pruritus | Nausea and Vomiting Following Administration of Anaesthetic Agent

Norway
University of Nottingham

Unknown

Vascular Changes During Colorectal Surgery (MaMiFlo)

Patients Undergoing Open Resection of Colorectal Tumours

United Kingdom
Dow University of Health Sciences

Not yet recruiting

"The Effect Of Subcutaneous Epinephrine Dosage On Blood Loss In Surgical Incision"

To Determine the Optimal Doses of Adrenaline in Preventing Blood Loos in Participants Undergoing Supraclavicular Flap Surgery
Second Affiliated Hospital, School of Medicine,...

Completed

Development and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral Nutrition Patients (RFS)

Development and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral Nutrition

China
Rambam Health Care Campus

Unknown

Fungal Infection After Oral Cavity Surgeries

Prevalence of Fungal Infection in Patients Undergoing Oral Cavity Surgery Without Treatment With Antifungal Drug
Ataturk University

Completed

Combined Spinal Epidural Anesthesia in Obese Patients Undergoing Cesarean Surgery

Obesity | Pregnancy Related | Cesarean Section Complications | Hypotension | Spinal Anaesthetic Poisoning of Undetermined Intent

Turkey
University Medical Centre Ljubljana

Completed

Regional Citrate Anticoagulation in Plasma Exchange Treatment

Focal Segmental Glomerulosclerosis | Guillain-Barre Syndrome

Slovenia
The Hospital for Sick Children

Completed

Determining the Extent of Diffusion Tensor Abnormalities in Focal Cortical Dysplasia (FCP)

Epilepsy | Focal Cortical Dysplasia

Canada
Basaksehir Cam & Sakura Şehir Hospital

Recruiting

The Effect of Fascia Iliaca Compartment Block (FICB) on QoR-15 Score in Partial Hip Arthroplasty Surgery (QoR-15)

Anesthesia, Local | Post Operative Pain | Fracture of Hip | QoR-15

Turkey
Hospital San Carlos, Madrid

Completed

"Oncologic Results and Risk Factors for Recurrence in Patients With Locally Advanced Rectal Cancer and Pathologic Complete Response After Neoadjuvant Treatment. Results From an Observational Retrospective Multicenter Long-term Follow-up Study".

Rectal Cancer Stage II | Rectal Cancer Stage III | Rectal Cancer, Adenocarcinoma | Distant Metastasis | Local Recurrence of Malignant Tumor of Rectum

Spain
Rutgers, The State University of New Jersey

Terminated

Use of Transesophageal Echocardiography to Measure Intraoperative Renal Resistive Index and Predict Acute Renal Injury

Subjects Undergoing Cardiac or Major Surgery Where TEE is Used as a Matter of Routine

United States
University Hospital, Ghent

Completed

Pathophysiological Mechanisms of Hepatopulmonary Influence in the Fontan Circulation

Children With a Univentricular Heart Undergoing Surgery for Creation of a Fontan Circulation

Belgium
University Hospital, Montpellier

Completed

SvO2 Trigger in Transfusion Strategy After Cardiac Surgery (ReTSEACS)

Undergoing Nonemergent Cardiac Surgery | Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure) | Anemia (<9g/dL) Requiring Blood Transfusion | Hemodynamic and Respiratory Stability | Bleeding Graded as Insignificant, Mild, Moderate of Universal Definition of Perioperative...

France
University of British Columbia

Completed

Cerebral Palsy Hip Health Related Quality of Life

Quality of Life | Cerebral Palsy | Patient Undergoing Hip Surgery

Canada
Hospices Civils de Lyon

Completed

Brain Maturation in Children With Localization Related Epilepsy (DYNAMAT)

Benign Childhood Epilepsy With Centro-temporal Spikes (BCECTS) | Focal Cryptogenic Epilepsy of Childhood | Cryptogenic Epilepsy of Childhood

France
Assistance Publique - Hôpitaux de Paris

Completed

Comparison of the Accuracy of the Neurological Prognosis at 6 Months of Traumatic Brain Injury Between Junior and Senior Doctors (PREDICT II)

Prognosis of Neurological Outcome at 6 Months in Patients Undergoing Traumatic Brain Injury

France
The Hospital for Sick Children
University of Calgary

Completed

Medi-Port Pilot Randomized Controlled Trial

Actively Undergoing Cancer Treatment | 4-9 Years of Age | At Least 1 Month From Diagnosis | Able to Speak and Understand English | Presenting to Clinic for at Least a 2nd Subcutaneous Port Needle Insertion

Canada
Assistance Publique - Hôpitaux de Paris

Recruiting

Assessment of the Applicability and Acceptability of an Algorithm to Guide the Prescription of 1st and 2nd Generation Cephalosporins as Part of Intraoperative Antibiotic Prophylaxis in Patients With a Declared Allergy to Penicillin (PROPHYLAL)

Adult Patients Who Declare an Allergy to Penicillin During Anaesthetic Consultation Without Any Allergy Work up That Could Confirm This Declaration | Good Comprehension of French Language

France
Erzincan University

Completed

Is Masseteric Nerve Block Effective in Myofascial Pain

Local Anesthesia | Myofascial Trigger Point Pain | Myofascial Pain - Dysfunction Syndrome of TMJ

Turkey
Shanghai 6th People's Hospital

Recruiting

LPB Combined With QLB Using Single-needle Technique (LPQLB-SNT) for Hip Arthroplasty (LPQLB-SNT)

Anesthesia, Local | Hip Fractures | Hip Osteoarthritis | Osteonecrosis of Femoral Head

China
Datascope Corp.

Terminated

ACTIONS - Aortic Counterpulsation to Improve Outcomes in Noncardiac Surgery (ACTIONS)

Patients With History of Ischemic Heart Disease With LV Dysfunction Undergoing Noncardiac Surgery

United States
University of Chicago

Completed

Prevalence Of Internal Pudendal Artery Disease In Patients With Erectile Dysfunction Undergoing Diagnostic Coronary Angiography

To Assess the Presence of Internal Pudendal Artery Disease in Patients With Erectile Dysfunction Undergoing Coronary Angiography

United States
University Hospital, Linkoeping
Ahmed Mohamed Abdelrahman; Mahmoud Ahmed Mewafy; Abdelrhman Alshawadfy; Haidi Abd-Elzaher and other collaborators

Completed

Ultrasound Guided Bilateral Superficial Cervical Plexus Block in Patients Undergoing Total Thyroidectomy. (BSCPB_Block)

Postoperative Pain | Analgesia Obtained With a Local Wound Infiltration of Lidocain | Analgesia Obtained With a Ultrasound Guided Cervical Plexus Block Using Lidocain

Sweden
Lorenzo Livi

Unknown

Phase II Randomized Trial of Radiation Therapy in Oligometastatic mCRPC Prostate Cancer (ARTO) (ARTO)

Rate of PSA Response in Oligometastatic,CRPC Undergoing SBRT in Combination With Abiraterone Acetate (AA), Compared to Patients Treated With AA Alone
Karolinska University Hospital

Unknown

Elimination of CO2-insufflation-induced Hypercarbia in Open Heart Surgery

Adult Patients Undergoing Open Heart Replacement of the Aortic Valve for Aortic Stenosis or Insufficiency

Sweden
Syracuse University
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Effects of Octanoic Acid for Treatment of Essential Voice Tremor

Essential Voice Tremor | Voice Tremor | Vocal Tremor | Essential Tremor of Voice

United States
Universitätsklinikum Hamburg-Eppendorf

Terminated

Quality of Life After Biliodigestive Anastomosis (BDA) or Stents to Treat Biliary Obstruction in Pancreas Cancer (BYPAPA)

Advanced Cancer | Jaundice | Pancreatic Cancer Non-resectable | Local Tumor Spread | Metastasized

Germany
ethisch.comite@uza.be

Recruiting

Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea

Nervous System Diseases | Sleep Apnea Syndromes | Sleep Apnea, Obstructive | Apnea | Sleep Disorders, Intrinsic | Sleep Wake Disorders | Sleep Apnea | Propofol | Respiratory Tract Disease | Physiological Effects of Drugs | Central Nervous System Depressants | Respiration Disorder | Midazolam | Dyssomnia | Hypnotics and... and other conditions

Belgium
University of Rostock

Completed

Laryngeal Injuries After Anesthesia Induction With Three Different Sevoflurane Concentrations (Without Muscle Relaxant) (SEVODosage)

Other Specified Injuries of Vocal Cord, Sequela

Germany
Johann Wolfgang Goethe University Hospital

Completed

Pulmonary Function Test, Bronchial Hyperresponsiveness and Quality of Life in Patients With Vocal Cord Dysfunction (VCD) (VCD)

Dyspnea

Germany
Università degli Studi dell'Aquila

Completed

Dexamethasone for the Prevention of Recurrent Laryngeal Nerve Palsy

Benign Neoplasm of Thyroid Gland | Malignant Neoplasm of Thyroid

Italy
NYU Langone Health

Completed

A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD

Epilepsy | Tuberous Sclerosis Complex | Focal Cortical Dysplasia

United States
University Hospital Plymouth NHS Trust
University of Plymouth

Completed

Recurrence After Whipple's (RAW) Study

Pancreatic Cancer | Surgery | Bile Duct Cancer | Pancreatic Ductal Adenocarcinoma | Survivorship | Cholangiocarcinoma, Extrahepatic | Cancer Recurrence | Recurrent Cancer | Pancreatic Ductal Carcinoma | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampullary Cancer | Cholangiocarcinoma Resectable | Cancer... and other conditions

Spain, United Kingdom, Australia, Austria, Italy, Mexico, Sudan, Pakistan
Ain Shams University
Ain Shams Maternity Hospital

Completed

Prediction of Neonatal Respiratory Distress Syndrome in Preterm Fetuses by Assessment of Fetal Lung Volume by Vocal and Pulmonary Artery Resistance Index a Pilot Study

Fetal Lung Volume of Preterm Fetuses Measured by VOCAL, PA-RI Measured by Pulsed Doppler

Egypt
GRIN Therapeutics, Inc.

Recruiting

A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Tuberous Sclerosis Complex | Focal Cortical Dysplasia

Spain, United Kingdom, Australia, Belgium, Canada, Italy, Poland
Mina Wageh Mohareb
Al-Azhar University

Recruiting

Individualized and Combined Effects of Diabetes and Smoking on the Antiplatelet Activity of Ticagrelor in Acute Myocardial Infarction Patients Undergoing Primary PCI

Individualized and Combined Effects of Smoking and Diabetes on the Antiplatelet Activity in Patients Undergoing Primary Percutaneous Coronary Intervention

Egypt
Esraa Mostafa Ahmed Abdel Aal

Not yet recruiting

Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure (seizure)

Localization-Related (Focal) (Partial) Idiopathic Epilepsy and Epileptic Syndromes With Seizures of Localized Onset | TRAIL: Tumor Necrosis Factor Related Apoptosis Inducing Ligand MCP-2 | MCP-2: Monocyte Chemo-attractant Protein-2
University of Texas Southwestern Medical Center
Massachusetts General Hospital

Recruiting

Dystonia Genotype-Phenotype Correlation

Dystonia | Dystonia; Idiopathic | Dystonia, Primary | Dystonia, Secondary | Dystonia, Familial | Dystonia Disorder | Dystonias, Sporadic | Dystonia; Orofacial | Dystonia Lenticularis | Dystonia, Paroxysmal | Dystonia 6 | Dystonia 5 | Dystonia 8 | Dystonia 9 | Dystonia 19 | Dystonia 10 | Dystonia 11 | Dystonia 20 | Dystonia 12 | Dystonia... and other conditions

United States
NYU Langone Health

Withdrawn

Turmeric as Treatment in Epilepsy

Epilepsy | Tuberous Sclerosis | Dravet Syndrome | Focal Seizures | Lennox-Gastaut Syndrome

United States
University of California, Davis
Pediatric Emergency Care Applied Research Network

Not yet recruiting

Screening Emotions in Adolescents at the Hospital for mTBI (SEARCH-mTBI)

Brain Injuries | Intracranial Hemorrhages | Diffuse Axonal Injury | Head Injury | Skull Fractures | Head Injury Trauma | Brain Injury Traumatic Mild | Brain Injuries, Acute | Head Injury With Intracranial Hemorrhage | Brain Injury Traumatic Focal With Loss of Consciousness

United States
SpeciCare
University of Washington; Georgia Institute of Technology; Predictive Oncology; Netnoid... and other collaborators

Recruiting

The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) (PIONEER)

Melanoma | Sarcoma | Renal Cell Carcinoma | Breast Cancer | Hepatocellular Carcinoma | Transitional Cell Carcinoma | Glioblastoma Multiforme | Cholangiocarcinoma | Small-cell Lung Cancer | Oligodendroglioma | Cancer of Head and Neck | Cancer of Liver | Cancer of Pancreas | Cancer of Brain and Nervous System | Adrenal... and other conditions

United States
University of California, Los Angeles
Université de Montréal

Withdrawn

Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery

Stroke | Epilepsy | Tuberous Sclerosis | Sturge-Weber Syndrome | Focal Cortical Dysplasia | Hemimegalencephaly | Polymicrogyria | Rasmussen Encephalitis | Gliosis | Tumor, Brain

United States, Canada
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom

Clinical Trials on Underdosing of Local Anesthetics

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Iran

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations