Clinical Trials on Unresectable Bone Sarcoma

Total 29481 results

University of Louisville

Completed

Study To Examine Toxicity Of Allogeneic Stem Cell Transplantation For Relapsed Or Therapy Refractory Ewings Sarcoma (Ewing/Allo)

EWINGS SARCOMA

United States
Children's Cancer Hospital Egypt 57357

Withdrawn

Post-operative Radiotherapy in Poor Responders Ewing's Sarcoma Patients

Ewing's Sarcoma

Egypt
Washington University School of Medicine

Completed

Dacarbazine for Metastatic Soft Tissue and Bone Sarcoma

Sarcoma

United States
Universitaire Ziekenhuizen KU Leuven

Recruiting

Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients (QOLSarcoma)

Soft Tissue Sarcoma | Bone Sarcoma

Belgium
Shenzhen Geno-Immune Medical Institute
The Seventh Affiliated Hospital of Sun Yat-sen University; Shenzhen Children...

Recruiting

Combination Immunotherapy Targeting Sarcomas

Sarcoma | Ewing Sarcoma | Osteoid Sarcoma

China
Grupo Espanol de Investigacion en Sarcomas

Completed

Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young Adults

Ewing's Sarcoma

Spain
King Faisal Specialist Hospital & Research Center

Unknown

Phase II Pilot Study of Vincristine, Adriamycin, Actinomycin D, Ifosfamide Combination Chemotherapy in Ewing's Sarcoma

Ewing's Sarcoma
National Cancer Institute (NCI)

Completed

Blood and Tissue Study of Patients in NIH Protocol 08-C-0800

Sarcomas

United States
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma

Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Uterine Corpus Leiomyosarcoma

United States
Incyte Corporation

Terminated

A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma

Relapsed Ewing Sarcoma

United States, Spain, United Kingdom, Italy
Dana-Farber Cancer Institute

Completed

Cabozantinib With Topotecan-Cyclophosphamide

Refractory Ewing Sarcoma | Refractory Osteosarcoma | Relapsed Ewing Sarcoma | Relapsed Osteosarcoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma

Recurrent Ewing Sarcoma | Metastatic Ewing Sarcoma

United States
Massachusetts General Hospital

Terminated

A Pilot Study of Neoadjuvant Therapy With Gemcitabine and Cisplatin in Patients With Resectable or Unresectable Intrahepatic Cholangiocarcinoma

Resectable Intrahepatic Cholangiocarcinoma | Unresectable Intrahepatic Cholangiocarcinoma

United States
Centre Leon Berard

Recruiting

Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas (REGOSTA)

Osteosarcoma | Ewing Sarcoma | Chondrosarcoma | Leiomyosarcoma | Angiosarcoma | Bone Sarcoma | Undifferentiated Pleomorphic Sarcoma

France
M.D. Anderson Cancer Center

Completed

Aerosol L9-NC and Temozolomide in Ewing's Sarcoma

Ewing's Sarcoma

United States
Fudan University

Terminated

Study on VCD/IE in the Patients With Ewing's Sarcoma Family of Tumors (ESFT)

Ewing's Sarcoma

China
IRCCS Azienda Ospedaliero-Universitaria di Bologna
S. Anna Hospital

Unknown

Hematopoietic Stem Cell Transplantation From Human Leukocyte Antigen (HLA) Compatible Donor in Ewing Sarcomas and Soft Tissues Sarcomas

Soft Tissue Sarcoma | Ewing

Italy
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy Before Surgery for Localized, Resectable Soft Tissue Sarcoma of the Extremity and Superficial Trunk

Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Resectable Soft Tissue Sarcoma | Stage I Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IB Soft Tissue Sarcoma of the Trunk and Extremities...

United States
Universität Duisburg-Essen
Ruhr University of Bochum

Completed

Exercise Intervention for Bone Tumor Patients (proGAIT)

Bone Sarcoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

GISAR German Interdisciplinary Sarcoma Registry (GISAR)

Sarcoma | Carcinosarcoma | Sarcoma,Soft Tissue | Sarcoma of Bone

Germany
Italian Sarcoma Group

Completed

Protocol for the Treatment of Metastatic Ewing Sarcoma (EW-2)

Ewing's Sarcoma (ES)

Italy
Institut Bergonié
Ipsen; MSD France

Recruiting

Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas (PEMBROCABOSARC)

Osteosarcoma | Ewing Sarcoma | Soft Tissue Sarcoma Adult | Undifferentiated Pleomorphic Sarcoma | Advanced Soft-tissue Sarcoma

France
Baylor College of Medicine
National Cancer Institute (NCI); Stand Up To Cancer; Center for Cell and Gene... and other collaborators

Recruiting

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

Sarcoma | Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma | HER-2 Protein Overexpression | Undifferentiated Sarcoma

United States
Institut Curie
UNICANCER

Completed

First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 Years (CombinaiR3)

Ewing Sarcoma Family of Tumors

France
Istituto Ortopedico Rizzoli
Regione Emilia-Romagna

Completed

Assessment of MGMT Promoter Methylation in Advanced Ewing Sarcoma Treated With Temozolomide and Irinotecan (MGMTLiberati)

Ewing Sarcoma Family of Tumors

United Kingdom, Italy
Pfizer

Completed

Study Of CP-751,871 In Patients With Ewing's Sarcoma Family Of Tumors

Ewing's Sarcoma Family of Tumors

Spain, France, United States, Italy, Australia, Germany, United Kingdom, Israel, Canada, Brazil, Chile
M.D. Anderson Cancer Center

Suspended

Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study

Recurrent Osteosarcoma | Refractory Osteosarcoma | Metastatic Osteosarcoma | Unresectable Osteosarcoma | Locally Advanced Osteosarcoma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma

Newly Diagnosed Ewing Sarcoma

United States
Italian Sarcoma Group
Scandinavian Sarcoma Group; Cooperative Osteosarcoma Study Group

Completed

European Study in Bone Sarcoma Patients Over 40 Years (EUROBOSS)

Osteosarcoma | Spindle Cell Sarcoma of Bone

Italy, Germany, Sweden
University Hospital Muenster

Completed

Study in Localized and Disseminated Ewing Sarcoma (EWING2008)

Ewing's Sarcoma

Germany
Centre Leon Berard
Ministry of Health, France

Completed

Study of Continuous Dosing of Sunitinib in Non GIST Sarcomas With Concomitant Radiotherapy

Non GIST Sarcomas

France
Massachusetts General Hospital

Completed

Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcoma

Ewing's Sarcoma

United States
Jonsson Comprehensive Cancer Center

Recruiting

Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)

Abdominopelvic Sarcomas

United States
Case Comprehensive Cancer Center

Recruiting

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

Relapsed Sarcomas

United States
Brown University
Actuate Therapeutics Inc.

Withdrawn

A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas

Sarcoma | Soft Tissue Sarcoma | Leiomyosarcoma | High Grade Sarcoma | Liposarcoma | Rhabdomyosarcoma | Angiosarcoma | Bone Sarcoma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Metastatic Sarcoma | Myxofibrosarcoma | Spindle Cell Sarcoma

United States
Dana-Farber Cancer Institute
Harvard University; Conquer Cancer Foundation; Alex's Lemonade Stand Foundation; Sam Day Foundation

Recruiting

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

Ewing Sarcoma of Bone | Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor | Peripheral Primitive Neuroectodermal Tumor of Bone | High-grade Osteosarcoma | Ewing Sarcoma of Soft Tissue | Peripheral Primitive Neuroectodermal Tumor of Soft Tissue

United States
Jonathan Trent, MD, PhD
Merck Sharp & Dohme LLC; Pfizer

Completed

Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas

Alveolar Soft Part Sarcoma | Soft Tissue Sarcomas

United States
Dana-Farber Cancer Institute
1 Million 4 Anna Foundation; Carson Sarcoma Foundation; Teaming up to Fight Childhood... and other collaborators

Completed

Palbociclib + Ganitumab In Ewing Sarcoma

Ewing Sarcoma | Ewing's Sarcoma Recurrent

United States
Peking University People's Hospital

Unknown

TQB3525 for Advanced Bone Sarcomas With PI3KA Mutations or PTEN Loss (TQBSP)

Safety Issues | Efficacy, Self

China
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in Treating Patients With Advanced Soft Tissue Sarcoma or Recurrent Bone Sarcoma

Sarcoma
Sumitomo Pharma America, Inc.

Terminated

Phase 1, First-in-human Study of Oral TP-1287 in Patients With Advanced Solid Tumors

Sarcoma | Ewing Sarcoma | Advanced Solid Tumors | Synovial Sarcoma | Dedifferentiated Liposarcoma

United States
Children's Hospital of Philadelphia
Children's Hospital Colorado; Exelixis; Alex's Lemonade Stand Foundation

Recruiting

Cabozantinib With Ifosfamide in Ewing's Sarcoma and Osteosarcoma

Osteosarcoma | Ewing Sarcoma

United States
Istituto Ortopedico Rizzoli
International Agency for Research on Cancer

Recruiting

Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma (Metabol-Sarc)

Osteosarcoma | Ewing Sarcoma

Italy
Sarcoma Alliance for Research through Collaboration

Completed

ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing Sarcoma

Ewing Sarcoma

United States, United Kingdom
Jonsson Comprehensive Cancer Center
NantCell, Inc.

No longer available

Single Patient Expanded Access to Ganitumab for Metastatic Ewing Sarcoma

Ewing Sarcoma
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of Tumors

Sarcoma

United States, Canada, Puerto Rico, Australia
University of Louisville

Withdrawn

A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma (ASCT)

Ewing Sarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Tissue Samples From Patients With Ewing Sarcoma

Sarcoma
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's Sarcoma

Sarcoma

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas

Rhabdomyosarcoma | Ewing's Sarcoma

United States

Clinical Trials on Unresectable Bone Sarcoma

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