Clinical Trials on Unresectable Bone Sarcoma

Total 29473 results

Istituto Ortopedico Rizzoli

Recruiting

Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma

Ewing Sarcoma

Italy
Institut Curie

Completed

Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives (GENEWING)

Sarcoma

France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker in Tissue Samples From Patients With Ewing Sarcoma

Sarcoma
University Hospital Muenster
Medical Research Council

Unknown

Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma

Sarcoma

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Withdrawn

Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly Diagnosed Localized Ewing's Sarcoma

Sarcoma
Children's Cancer and Leukaemia Group

Completed

Irinotecan in Treating Patients With Newly Diagnosed Ewing's Sarcoma

Sarcoma

United Kingdom, Ireland
Shanghai Ninth People's Hospital Affiliated to...

Unknown

Radiotherapy Concurrent With Apatinib in Advanced Soft Tissue and Bone Sarcomas of Head and Neck--RASS Study (RASS)

Sarcoma | Head and Neck Cancer | Soft Tissue and Bone Tumor

China
Sidnei Epelman

Unknown

Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Rhabdomyosarcoma and Other Soft Tissue Sarcomas

Refractory or Relapsed RMS and Soft Tissue Sarcomas

Brazil
University Hospital Tuebingen
Cooperative Weichteilsarkom Study Group; Deutsches Konsortium fürTranslationale... and other collaborators

Recruiting

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision) (PerVision)

Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma

Germany
The Netherlands Cancer Institute
Royal Marsden NHS Foundation Trust

Terminated

Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients (PASART-2)

Sarcoma | Soft Tissue Sarcomas

United Kingdom, Netherlands
Massachusetts General Hospital
Beth Israel Deaconess Medical Center; Brigham and Women's Hospital

Enrolling by invitation

LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology

Sarcoma | Soft Tissue Sarcoma | Venous Thromboembolism | Bone Metastases | Hematoma | Bone Sarcoma | Anticoagulant-induced Bleeding

United States
Eisai Inc.

Completed

Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)

Ewing Sarcoma | Non-rhabdomyosarcoma Soft Tissue Sarcoma | Relapsed/Refractory Rhabdomyosarcoma

United States
National Cancer Institute (NCI)

Completed

Prognostic Value of a Positive RT-PCR Test in Patients With Ewing Sarcoma

Non-Metastatic Ewings Sarcoma

United States
Anna Raciborska
Wroclaw Medical University

Recruiting

To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)

Ewing Sarcoma

Poland
Peking University People's Hospital

Recruiting

Irinotecan and Temozolomide for Ewing Sarcoma

Ewing Sarcoma

China
Sarcoma Alliance for Research through Collaboration
National Cancer Institute (NCI); Janssen Scientific Affairs, LLC; National Institutes...

Active, not recruiting

SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients (U01CA236220)

Ewing Sarcoma

United States
St. Jude Children's Research Hospital

Active, not recruiting

Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas

Sarcoma, Soft Tissue | Osteosarcoma | Sarcoma, Ewing | Rhabdomyosarcoma | Sarcoma, Bone | Non-rhabdomyosarcoma Soft-tissue Sarcoma

United States
Italian Sarcoma Group
French Sarcoma Group; Grupo Espanol de Investigacion en Sarcomas

Active, not recruiting

Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy

Localized High-risk Soft Tissue Sarcomas of the Extremities and Trunk Wall in Adults

Spain, Italy
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor

Ewing Sarcoma | Ewing-Like Sarcoma

United States
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma and Osteosarcoma (SeliSarc)

Sarcoma,Soft Tissue

Spain
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma

Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Advanced Dedifferentiated Liposarcoma | Metastatic Dedifferentiated Liposarcoma | Locally Advanced Dedifferentiated Liposarcoma | Unresectable Dedifferentiated...

United States
Blokhin's Russian Cancer Research Center

Recruiting

Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors

Sarcoma | Neoplasms, Connective and Soft Tissue | Osteosarcoma | Neoplasms, Connective Tissue | Sarcoma of Bone

Russian Federation
Peking University People's Hospital

Unknown

Anlotinib and Irinotecan for Ewing Sarcoma

Ewing's Tumor Metastatic

China
AEterna Zentaris
Sarcoma Alliance for Research through Collaboration

Completed

A Trial of Perifosine in Patients With Chemo-Insensitive Sarcomas

Chondrosarcomas | Alveolar Soft Part Sarcomas | Extra Skeletal Myxoid Chondrosarcomas
National Cancer Institute (NCI)

Terminated

Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma

High Grade Sarcoma | Metastatic Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Leiomyosarcoma | Myxofibrosarcoma | Metastatic Malignant Peripheral Nerve Sheath Tumor | Metastatic Synovial Sarcoma | Metastatic Undifferentiated... and other conditions

United States
Memorial Sloan Kettering Cancer Center
University of Oregon; University College, London; New York Presbyterian Hospital and other collaborators

Completed

Dynamic Contrast Enhanced MRI(DCE-MRI)of Bone Tumors

Sarcoma | Bone Tumor

United States
Jonsson Comprehensive Cancer Center
California Institute for Regenerative Medicine (CIRM)

Terminated

Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer (NYESO SCT)

Sarcoma | Unresectable Malignant Neoplasm | Locally Advanced Malignant Neoplasm | HLA-A*0201 Positive Cells Present | NY-ESO-1 Positive

United States
Centre Leon Berard

Recruiting

Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients (REGOMAIN)

Osteosarcoma | Bone Sarcoma

France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Cytarabine in Treating Young Patients With Recurrent or Refractory Ewing's Sarcoma

Sarcoma

United States, Canada, Australia, Puerto Rico
Universitaire Ziekenhuizen KU Leuven

Unknown

Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults (FUBEO)

Osteosarcoma | Ewing Sarcoma

Belgium
H. Lee Moffitt Cancer Center and Research Institute
National Pediatric Cancer Foundation

Active, not recruiting

Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma

Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Rhabdomyosarcoma

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 With or Without Autologous T Cell Transplantation in Recurrent Pediatric Sarcomas

Rhabdomyosarcoma | Ewing's Sarcoma

United States
Centre Georges Francois Leclerc

Completed

Validation of a Genetic Signature to Predict the Development of Sarcomas (PREDISARC)

Genetic Signature in Development of Sarcomas

France
Azienda Ospedaliera Ospedale Infantile Regina Margherita...
Associazione Italiana Ematologia Oncologia Pediatrica

Recruiting

Genomic Profiles Analysis in Children, Adolescents and Young Adult With Sarcomas

Diagnosed or Relapsed/Refractory Sarcomas

Italy
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; Merck Sharp & Dohme LLC; Dana-Farber Cancer Institute and other collaborators

Completed

Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors

Solid Tumors | Relapsed/Refractory Sarcomas

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Ewing Sarcoma of Bone | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Memorial Sloan Kettering Cancer Center

Completed

Cytogenetic and Molecular Genetic Studies in Bone Sarcomas

Lung Cancer

United States
Patricia Bonilla
Hospital del Niño "Dr. José Renán Esquivel"

Unknown

Distal Tibia Sarcoma Treatment Using Allograft Arthrodesis of the Ankle

Bone Neoplasm

Panama
Peking University People's Hospital
Peking University Shougang Hospital; Shandong Cancer Hospital and Institute

Recruiting

Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing Sarcoma

Ewing Sarcoma

China
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma

Osteosarcoma | Ewing Sarcoma | Paget's Disease

United States
National University Hospital, Singapore

Unknown

Pilot Study of Expanded , Activated Haploidentical Natural Killer Cell Infusions for Sarcomas (NKEXPSARC)

Ewing Sarcoma | Rhabdomyosarcoma

Singapore
Di Wu

Not yet recruiting

Study of Anlotinib Hydrochloride and Toripalimab in Subjects With Unresectable or Metastatic Undifferentiated Pleomorphic Sarcoma

Undifferentiated Pleomorphic Sarcoma | Soft Tissue Sarcomas

China
University College, London
Richard Scowcroft Foundation

Terminated

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

Osteosarcoma | Spindle Cell Sarcoma of Bone

United Kingdom
National Cancer Institute (NCI)

Terminated

Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma

Sarcoma | Ewing Sarcoma

United States
Gradalis, Inc.

Terminated

A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomide (VITA)

Sarcoma | Neoplasms | Neoplasms, Connective and Soft Tissue | Neoplasms by Histologic Type | Sarcoma, Ewing | Neoplasms, Bone Tissue | Neoplasms, Connective Tissue | Ewing Sarcoma | Rare Diseases | Ewing's Tumor Metastatic | Ewing Family of Tumors | Ewing's Sarcoma Metastatic | Ewing's Tumor Recurrent

United States
Centre Antoine Lacassagne

Recruiting

Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy (P1V2)

Osteosarcoma | Ewing Sarcoma | Chondrosarcoma | Chordoma

France
St. Jude Children's Research Hospital
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Bone Sarcoma

Bone Sarcoma

United States
Institut Bergonié
Ministry of Health, France; PharmaMar

Terminated

Efficacy and Safety of Plitidepsin in Patients With Advanced Unresectable or Metastatic, Relapsed/Refractory, Dedifferentiated Liposarcoma (DLPS): an Exploratory Phase II Multicenter Trial (APLIPO)

Adult Patients With Unresectable Locally Advanced or Metastatic, Relapsed/Refractory Dedifferentiated Liposarcoma

France
Kenny Rodriguez-Wallberg

Recruiting

Use of GnRHa During Chemotherapy for Fertility Protection (ProFertil)

Soft Tissue Sarcoma | Lymphoma | Osteosarcoma | Ewing Sarcoma | Acute Leukemia | Breast Cancer Female

Sweden
Assaf-Harofeh Medical Center

Unknown

A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma

Soft Tissue Sarcoma | Osteosarcoma | Chondrosarcoma | Bone Sarcoma | Desmoplastic Small Round Cell Tumor | Gastrointestinal Stromal Sarcoma | Ewing's Tumor Metastatic | Ewing's Tumor Recurrent

Clinical Trials on Unresectable Bone Sarcoma

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