Clinical Trials on Unresectable Solid Neoplasm

Total 108413 results

Chugai Pharmaceutical

Completed

A Study of ERY974 in Patient With Advanced Solid Tumors

Solid Tumors

United States, France, Netherlands
Hoffmann-La Roche

Completed

An Extension Study of Onartuzumab in Participants With Solid Tumors on Study Treatment Previously Enrolled in a Company Sponsored Study

Solid Tumor

Spain, Russian Federation, France, Japan, South Africa, Latvia, Serbia, Italy
Daiichi Sankyo Co., Ltd.

Completed

Phase 1 Study of DS-8895a in Subjects With Advanced Solid Tumors

Solid Tumors

Japan
Amsterdam UMC, location VUmc

Completed

Study of High-dose, Intermittent Sunitinib in Patients With Solid Tumors.

Solid Tumors

Netherlands
Shanghai Henlius Biotech

Unknown

A Phase I Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Anti-PD-1 Antibody (HLX10) in Combination With Avastin Biosimilar (HLX04) in Patients With Advanced Solid Tumors

Solid Tumor

China
AstraZeneca
Quintiles, Inc.

Completed

Absorption, Metabolism, Excretion and Pharmacokinetics of a Single Dose [14C]AZD2014 Followed by a Multiple Dose Phase (14C)

Solid Malignancies

United Kingdom
Eli Lilly and Company

Completed

A Phase 1 Study in Patients With Solid Tumors

Solid Tumors

United States
Daiichi Sankyo, Inc.

Completed

Dose Finding, Safety and Tolerability Study for AC220 to Treat Advanced Solid Tumors

Solid Tumors

United States
Eli Lilly and Company

Completed

Dose-Escalation Study of LY573636-sodium and Liposomal Doxorubicin in Patients With Advanced Solid Tumors

Solid Tumors

United States
Bristol-Myers Squibb

Terminated

Safety and Efficacy Study of Ulocuplumab and Nivolumab in Subjects With Solid Tumors (CXCessoR4)

Solid Tumor

United States, Finland
AGC Biologics S.p.A.

Completed

Study of NGR-hTNF Administered at High Doses in Patient With Advanced or Metastatic Solid Tumour

Solid Tumors

Italy
Merck Sharp & Dohme LLC

Terminated

Study of Safety and Pharmacokinetics of MK-8242 in Participants With Advanced Solid Tumors (P07650)

Solid Tumors
SuZhou Stainwei Biotech Inc.

Unknown

A Study of Anti-VEGF Monoclonal Antibody hPV19 in Patients With Solid Tumors

Solid Tumors

China
Genentech, Inc.

Completed

A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors

Solid Tumor

United States, France
Young Suk Park

Completed

A Multicenter, Open Label, Phase I Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Intravenous SAIT301 in Subjects With Advanced c-MET Positive (+) Solid Tumors Followed by Expansion in Selected Tumor Types

Solid Tumors

Korea, Republic of
Fondazione del Piemonte per l'Oncologia

Unknown

Target Therapies Resistance Molecular Profiling in Patients With Neoplastic Disease (PROFILING)

Solid Tumors

Italy
GlaxoSmithKline

Completed

Open-label Study of Topotecan and Pazopanib in Advanced Solid Tumors

Solid Tumours

United States, Netherlands
SynCore Biotechnology Co., Ltd.

Completed

A Dose Escalation Study of SCB01A in Subjects With Advanced Solid Tumors Who Have Failed Standard Therapy

Solid Tumors

Taiwan
Merck KGaA, Darmstadt, Germany

Completed

Japanese Phase 1 Trial of Sym004 in Solid Tumors

Solid Tumors

Germany
GlaxoSmithKline

Completed

A Dose Escalation Study of the Safety and Pharmacokinetics of GSK1363089 (Formerly XL880) Administered Orally to Subjects With Solid Tumors

Solid Tumours
GlaxoSmithKline

Completed

A Bioavailability Study of GSK1363089 in Subjects With Solid Tumors

Solid Tumours

United States
Maastricht Radiation Oncology

Completed

Phase I Clinical Study Combining L19-IL2 With SABR in Patients With Oligometastatic Solid Tumor (L19-IL2)

Solid Tumour

Netherlands
MedImmune LLC

Completed

A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI0639 in Advanced Solid Tumors

Solid Tumors

United States
St. Jude Children's Research Hospital
AstraZeneca; National Institutes of Health (NIH)

Completed

Study of ZD1839 Combined With Irinotecan and Vincristine in Pediatric Patients With Refractory Solid Tumors

Solid Tumors

United States
Alligator Bioscience AB

Completed

ADC-1013 First-in-Human Study

Neoplasms | Solid Tumors

United Kingdom, Denmark, Sweden
R-Pharm

Completed

Study of Ixabepilone (BMS-247550) in Patients With Solid Tumors

Solid Tumors
Genentech, Inc.

Terminated

Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors

Solid Tumors

United States
Kinex Pharmaceuticals Inc.
Atlantic Research Group

Completed

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oraxol in Subjects With Advanced Malignancies

Solid Tumor

United States
Georgetown University
United States Department of Defense

Completed

Phase I Study of Intravenous Artesunate for Solid Tumors

Solid Tumors

United States
Eisai Co., Ltd.

Completed

A Phase 1 Study of MORAb-004 in Patients With Solid Tumor (Study: MORAb-004-J081-103)

Solid Tumor

Japan
PharmaEngine

Completed

A Study of PEP02 in Combination With 5-fluorouracil (5-FU) and Leucovorin (LV) in Advanced Solid Tumors

Solid Tumor
The First People's Hospital of Lianyungang
Hengrui Yuanzheng Bio-Technology Co., Ltd.

Unknown

MASCT-I Treatment for Advanced Solid Tumor

Solid Tumors
Threshold Pharmaceuticals

Unknown

A Cardiac Safety Study of TH-302 in Patients With Advanced Solid Tumors

Solid Tumors

United States
Sanofi

Completed

Oral SAR245408 (XL147) and Oral MSC1936369B in Patients With Locally Advanced or Metastatic Solid Tumors

Solid Tumors

United States
Eisai Inc.

Completed

Study of Poly (ADP-Ribose) Polymerase (PARP) Inhibitor E7016 in Combination With Temozolomide in Subjects With Advanced Solid Tumors

Solid Tumors

United States
Daiichi Sankyo, Inc.

Withdrawn

Safety Study for Intravenous (IV) AC480 (AC480IV) to Treat Advanced Solid Tumors

Solid Tumors

United States
Takeda

Completed

A Phase 1 Study Evaluating the Safety, Tolerability and Pharmacokinetics of Trebananib (AMG 386 ) in Adult Japanese Participants With Advanced Solid Tumors

Neoplasms, Advanced Solid
Merck Sharp & Dohme LLC

Completed

A Study of MK2206 in Locally Advanced or Metastatic Solid Tumors (2206-007)

Solid Tumors
Cancer Institute and Hospital, Chinese Academy...
Beijing Shenogen Biomedical Co., Ltd

Completed

A Phase Ib Study to Assess Safety and Efficacy of Oral Icaritin in Advanced Solid Tumors

Solid Tumors

China
Endocyte

Terminated

A Study of Vintafolide (MK-8109) in Participants With Advanced Solid Tumor (MK-8109-011)

Solid Tumor
Nanjing Luye Sike Pharmaceutical Co., Ltd.

Unknown

Dose Escalation and Pharmacokinetic Study of Paclitaxel Liposome Injection in Treating Patients With Advanced Solid Tumor After Failure From Conventional Treatments

Solid Tumors

China
AGC Biologics S.p.A.

Completed

Study of NGR-hTNF in Combination With Cisplatin in Solid Tumor

Solid Tumors

Italy
EMD Serono

Terminated

First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid Tumors

Solid Tumors

United States
SCRI Development Innovations, LLC
Novartis

Terminated

LBH589 and Gemcitabine in the Treatment of Solid Tumors

Solid Tumors

United States
Washington University School of Medicine

Completed

A Phase I Study of Bi-Weekly rBBX-01 in Patients With Solid Tumors

Solid Tumors

United States
Galapagos NV

Completed

GLPG0187: Safety, Tolerability and Pharmacokinetics in Patients With Solid Tumors

Solid Tumors

Netherlands
Sanofi

Completed

Drug Interaction Study of SAR302503 in Patients With Solid Tumor

Solid Tumor

United States
Centre Hospitalier Universitaire Dijon

Completed

Effects of OM-174 in Adult Patients With Solid Tumors (OM-174)

Solid Tumors
Oncoethix GmbH

Unknown

A Phase I, First-in-man Study of OTX008 Given Subcutaneously as a Single Agent to Patients With Advanced Solid Tumors

Solid Tumors

Belgium, France
National University Hospital, Singapore

Completed

Study of Capecitabine In Patients With Solid Tumors

Solid Tumors

Singapore

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