Clinical Trials on Usher Syndromes in United Kingdom

Total 14154 results

ProQR Therapeutics

Terminated

Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, United Kingdom
Neurotech Pharmaceuticals
University of California, San Francisco

Completed

Retinal Imaging in CNTF -Releasing Encapsulated Cell Implant Treated Patients for Early-stage Retinitis Pigmentosa

Retinitis Pigmentosa | Usher Syndrome Type 2 | Usher Syndrome Type 3

United States
Imperial College London
Homerton University Hospital NHS Foundation Trust

Withdrawn

Combining Physical Therapy With Vestibular Stimulation to Improve Postural Stability in Pusher's Syndrome

Pusher Syndrome

United Kingdom
Jaeb Center for Health Research
Foundation Fighting Blindness

Active, not recruiting

Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A)

Usher Syndrome, Type 2A | Retinitis Pigmentosa 39

United States, Canada, France, Germany, Netherlands, United Kingdom
Sanofi

Active, not recruiting

A Study to Determine the Long-Term Safety, Tolerability and Biological Activity of SAR421869 in Patients With Usher Syndrome Type 1B

Usher's Syndrome

United States, France
ProQR Therapeutics

Active, not recruiting

Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Netherlands, United Kingdom, Germany
Sanofi

Terminated

Study of SAR421869 in Participants With Retinitis Pigmentosa Associated With Usher Syndrome Type 1B

Retinitis Pigmentosa | Usher Syndrome

United States, France
ProQR Therapeutics

Terminated

An Open-Label Extension Study to Evaluate Safety & Tolerability of QR-421a in Subjects With Retinitis Pigmentosa (HELIA)

Retinitis Pigmentosa | Usher Syndrome Type 2

United States, Canada, France
National Eye Institute (NEI)

Completed

Natural History and Genetic Studies of Usher Syndrome

Retinitis Pigmentosa | Usher Syndrome | Retinitis Pigmentosa Syndromic | Congenital Deafness | Retinitis Pigmentosa and Deafness

United States
National Eye Institute (NEI)

Completed

Study of Usher Syndromes, Type 1 and Type 2

Retinitis Pigmentosa

United States
ProQR Therapeutics

Completed

Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Stellar)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Canada, France
National Center for Research Resources (NCRR)
Oregon Health and Science University

Terminated

Study of Dietary N-3 Fatty Acids in Patients With Retinitis Pigmentosa and Usher Syndrome

Retinitis Pigmentosa | Usher Syndrome

United States
Ohio State University
National Institute on Deafness and Other Communication Disorders (NIDCD)

Recruiting

Auditory Neural Function in Implanted Patients With Usher Syndrome

Usher Syndrome | Cochlear Implantation

United States
National Center for Research Resources (NCRR)

Completed

A Genetic Analysis of Usher Syndrome in Ashkenazi Jews

Retinitis Pigmentosa | Usher Syndrome | Congenital Hearing Impairment

United States
Imperial College London

Active, not recruiting

Novel ICD Arrhythmia Detection Algorithm

Cardiomyopathies | Implantable Defibrillator User | ICD

United Kingdom
LumiraDx UK Limited

Completed

Evaluation of Precision and Accuracy of INR Measurements in a Point of Care Device (OPTIMAL) (OPTIMAL)

Atrial Fibrillation | Thrombophilia | Deep Vein Thrombosis | Antiphospholipid Syndrome | Pulmonary Embolism | Post-Myocardial Infarction Syndrome | Artificial Heart Device User

United Kingdom
St. Bartholomew's Hospital

Unknown

Erythropoietin (EPO) and Granulocyte-Colony Stimulating Factor (G-CSF) for Low-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

United Kingdom
Brighton and Sussex University Hospitals NHS Trust
Medtronic Vascular

Completed

Revascularisation or Medical Therapy in Elderly Patients With Acute Anginal Syndromes (RINCAL)

Acute Coronary Syndromes

United Kingdom
Abbott Medical Devices

Completed

A Clinical Evaluation of the Durata or Optisure High Voltage Leads and Ellipse VR ICD Undergoing MRI, an IDE Study (MRI Ready IDE)

Implantable Defibrillator User

Hungary, United States, Poland, Spain, United Kingdom
University College, London
King's College London; King's College Hospital NHS Trust; University of Oxford; Great Ormond Street Hospital for Children NHS Foundation Trust

Recruiting

Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET): Pilot (CADET Pilot)

Epilepsy | Lennox-Gastaut Syndrome, Intractable

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Cubital Tunnel Syndrome and Diffusion MRI: A Proof of Concept Study

Cubital Tunnel Syndrome

United Kingdom
Christian S. Meyhoff
Rigshospitalet, Denmark

Recruiting

Alert Frequency, Nurse, and Patient Satisfaction With a wCVSM Software Across Health Care Systems and Cultures

Postoperative Complications | Acute Medical Conditions | User Experience

United States, Germany, Netherlands, Norway, United Kingdom
Oxford University Hospitals NHS Trust

Unknown

Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants

Myelodysplastic Syndromes | Leukemia

United Kingdom
University of Portsmouth
Portsmouth Hospitals NHS Trust

Not yet recruiting

The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb Haemodynamics (HELP)

Compartment Syndrome Nontraumatic Lower Extremity

United Kingdom
Allergan

Terminated

Clinical Study to Evaluate Tear Characteristics Following Acute TrueTear™ Use

Dry Eye Syndromes

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Low-dose Interleukin-2 for the Reduction of Vascular Inflammation in Acute Coronary Syndromes - IVORY (IVORY)

Acute Coronary Syndromes

United Kingdom
University Hospitals Coventry and Warwickshire...
University College, London; University of Warwick

Not yet recruiting

A Sensorimotor Prosthesis for the Upper Limb (PROLIMB)

Amputation | Prosthesis User | Amputation; Traumatic, Hand | Prosthesis Durability

United Kingdom
King's College Hospital NHS Trust

Completed

The Efficacy and Safety of Lenalidomide Monotherapy in Red Blood Cell Transfusion Dependent Subjects With Myelodysplastic Syndrome (MDS) Associated With Del (5q) Abnormality

Myelodysplastic Syndromes

United Kingdom
Imperial College London
The Drummond Foundation (RAMC charity)

Recruiting

Chemical Analysis of Limb Microfluidics (CALM)

Compartment Syndrome of Leg | Limb Ischemia

United Kingdom
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Barts & The London NHS Trust
Cancer Research UK; Amgen

Unknown

Comparison Study of Standard Care Against Combination of Growth Factors Agents for Low-risk Myelodysplastic Syndromes (REGIME)

Myelodysplastic Syndrome

United Kingdom
University Hospital Birmingham NHS Foundation Trust

Completed

The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment Syndrome

Compartment Syndrome

United Kingdom
University of Wisconsin, Milwaukee

Completed

Biomechanical Assessment of Gait in Lower-Extremity-Amputees

Prosthesis User

United States
Össur Ehf
Indiana University

Recruiting

Connect TF - An Investigation of Function and Usability of a New Adaptable Socket System

Amputation | Prosthesis User

United States
University of the West of England
Royal United Hospital Bath NHS Trust

Completed

Self Soft Tissue Therapy for Fibromyalgia Syndrome

Fibromyalgia Syndrome

United Kingdom
King's College Hospital NHS Trust

Terminated

Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin (FB-ATG)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
Gulf Heart Association
Boston Scientific Corporation; Medtronic

Completed

The Gulf Implantable Cardioverter-Defibrillator Registry (GulfICD)

Implantable Defibrillator User

United Arab Emirates
University College, London
Barts & The London NHS Trust

Unknown

Coronary Mortality in South Asians: Aetiologic and Prognostic Effects (CALIBER)

Acute Coronary Syndromes

United Kingdom
Beth Israel Deaconess Medical Center
University of Colorado, Denver; Mayo Clinic; University of Pennsylvania; Emory... and other collaborators

Enrolling by invitation

TRAjectories and CLinical ExpeRiences of ICD Therapy Study (TRACER-ICD)

Implantable Defibrillator User

United States
George Mason University
National Institute for Biomedical Imaging and Bioengineering (NIBIB); Infinite...

Enrolling by invitation

Sonomyographic Upper Limb Prosthetics: A New Paradigm

Amputation | Prosthesis User

United States
Larisa Tereshchenko

Completed

Assessment of S-ICD Eligibility With 12-Lead ECG (EL-SID)

Implantable Defibrillator User

United States
Liberating Technologies, Inc.

Completed

Myoelectric Game Training and Outcomes

Amputation | Prosthesis | Prosthesis User

United States
Institute of Cancer Research, United Kingdom
Cancer Research UK; National Institute for Health Research, United Kingdom

Completed

Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome (SIGNIFY)

Li-Fraumeni Syndrome

United Kingdom
Imperial College London

Withdrawn

Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS) (SLIPS)

Short Bowel Syndrome

United Kingdom
Allergan

Completed

Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms

Dry Eye Syndromes

United Kingdom
Össur Ehf
Methodist Rehabilitation Center; Baker Orthotics & Prosthetics; Virginia Prosthetics...

Completed

An Investigation of Functional Improvements in the RHEO KNEE Compared to Hydraulic Microprocessor Controlled Knees (MPKs)

Amputation | Prosthesis User

United States
Aston University

Not yet recruiting

Photobiomodulation With REd vs BluE Light (REBEL)

Dry Eye Syndromes | Meibomian Gland Dysfunction | Blepharitis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Gastrectomy, Eating Behaviour and GLP-1

Gastric Cancer | Dumping Syndrome

United Kingdom
John Carroll University
University Hospital Southampton NHS Foundation Trust

Active, not recruiting

Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients

PTEN Hamartoma Tumor Syndrome

United States, United Kingdom
University College, London

Completed

SS-INQ Information Needs Questionnaire in Sjögren's Syndrome (SS-INQ)

Sjögren's Syndrome

United Kingdom

Clinical Trials on Usher Syndromes in United Kingdom

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