Clinical Trials on Vaccinia Virus Infection

Total 61015 results

Federal Budgetary Research Institution State Research...

Completed

Safety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 Years

Smallpox | Monkeypox | Cowpox | Vaccinia Virus Infection

Russian Federation
Federal Budgetary Research Institution State Research...

Completed

Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years

Smallpox | Monkeypox | Cowpox | Vaccinia Virus Infection

Russian Federation
Emergent BioSolutions
Centers for Disease Control and Prevention

Completed

VA-006 Vaccinia Vaccine (ACAM2000) for the Production of VIGIV

Smallpox Vaccine Adverse Reaction

United States
Federal Budgetary Research Institution State Research...

Completed

Study of the Safety, Tolerability, Pharmacokinetics of NIOCH-14 in Volunteers Aged 18-50 Years

Smallpox | Monkeypox | Cowpox | Vaccinia Virus Infection

Russian Federation
National Institute of Allergy and Infectious Diseases...

Completed

VRC 208: Dose, Safety and Immunogenicity of a Recombinant Modified Vaccinia Virus Ankara Ebola Vaccine, VRC-EBOMVA079-00-VP (MVA-EbolaZ), Administered Alone or as a Boost to cAd3-Ebola Vaccines in Healthy Adults

Healthy Adult Immune Responses to Vaccine

United States
HIV Vaccine Trials Network
South Africa AIDS Vaccine Initiative

Completed

Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults

HIV Seronegativity | HIV Preventive Vaccine

South Africa
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Trial to Evaluate the Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA)-Based Anti-Cytomegalovirus (CMV) Vaccine (Triplex®)

HIV Infections | Cytomegalovirus Infections | Vaccine

United States
International AIDS Vaccine Initiative
University of Rochester; Aaron Diamond AIDS Research Center

Completed

Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA) HIV Vaccine in HIV Uninfected Adults

HIV Infection

United States
University of Vermont
International Centre for Diarrhoeal Disease Research, Bangladesh; Thrasher... and other collaborators

Completed

The Effects of Increased Inoculum on Oral Rotavirus Vaccine Take and Immunogenicity

Rotavirus Infection | Vaccine Response Impaired | Vaccine Virus Shedding

Bangladesh
University Medical Center Groningen
Radboud University Medical Center; Maastricht University Medical Center; UMC... and other collaborators

Completed

PREPARE-iVAC Trial (PREPARE-iVAC)

Vaccine Response | Immunosuppression | COVID-19 Vaccines | Varicella Zoster Vaccine

Netherlands
Centers for Disease Control and Prevention, China

Recruiting

Combined Immunization of COVID-19 Inactivated Vaccine With QIV and PPV23 (QIV;PPV23)

Pneumococcal Vaccines | Safety | Influenza Vaccines | COVID-19 Vaccines | Immunogenicity, Vaccine

China
Bandim Health Project

Enrolling by invitation

Measles Vaccination at Health System Contacts

Mortality | Measles Vaccine | Hospital Admission | Non-specific (Heterologous) Effects of Vaccines

Guinea-Bissau
Children's National Research Institute
Pfizer

Completed

Comparison of Immunization Quality Improvement Dissemination Study (CIzQIDS)

Immunization | Hepatitis B Vaccine | Poliovirus Vaccine, Inactivated | DTaP Vaccine | MMR Vaccine | HIB-vaccine | Chickenpox Vaccine | Pneumococcal Polysaccharide Vaccine
Bavarian Nordic
US Army Medical Research Institute of Infectious Diseases

Completed

A Non-inferiority Trial to Compare MVA-BN® Smallpox Vaccine to ACAM2000®

18-42 Year Old Healthy Vaccinia-naïve Subjects

Korea, Republic of
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating A 13-Valent Pneumococcal Conjugate Vaccine Administered to Infants in Taiwan

Vaccines | Pneumococcal Conjugate Vaccine

Taiwan
Sinocelltech Ltd.

Recruiting

A Phase I Safty and Immunogenicity Study of SCT1000 in Healthy Women Aged 18 to 45 Years

HPV Infection Vaccine Safety SCT1000

China
Kanazawa Medical University
Merck Sharp & Dohme LLC

Unknown

Changes in the Prevalence of Oncogenic HPV Types

Papillomavirus Infections | Papillomavirus Vaccines
Limited Liability Company Pharm Aid

Completed

Safety and Immunological Efficacy of the Pentavalent Rotavirus Vaccine - Rota-V-Aid™ (Live Attenuated Oral, Freeze-dried) at Healthy Adults Aged 18 to 45 Years.

Rotavirus Infections | Rotavirus Vaccines

Russian Federation
Washington University School of Medicine

Not yet recruiting

Evaluating the Human Immune Response to the JYNNEOS Vaccine

Virus Diseases | Vaccinia

United States
Beijing Luzhu Biotechnology Co., Ltd.

Recruiting

A Study to Evaluate Safety and Tolerability of a Recombinant Herpes Zoster Vaccine

Herpes Zoster | Vaccine-Preventable Diseases

United States
Institut National de la Santé Et de la Recherche...

Unknown

Transcriptomics Signature of Anti Vaccinia Memory B Cells

Healthy
National Center for AIDS/STD Control and Prevention...

Completed

Safety and Immunogenicity Study of AIDS Vaccine (Combined Use of DNA Vaccine and Recombinant Vaccinia Virus Tiantan)

AIDS

China
GlaxoSmithKline

Completed

This Study Will Evaluate the Immunogenicity, Reactogenicity and Safety of the Routine Infant Vaccines Pediarix®, Hiberix® and Prevenar 13® When Co-administered With GlaxoSmithKline (GSK) Biologicals' Liquid Human Rotavirus Vaccine (HRV) as Compared to GSK's Licensed Lyophilized Vaccine

Rotavirus Infection | Rotavirus Vaccines

United States
National Institute of Allergy and Infectious Diseases...

Withdrawn

SIGA-246 to Treat Smallpox

Vaccinia

United States
Dynavax Technologies Corporation

Completed

Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult Volunteers

Herpes Zoster | Vaccine-Preventable Diseases | Shingles

Australia
Bavarian Nordic

Completed

A Trial to Evaluate Immunogenicity and Safety of Three Consecutive Production Lots of IMVAMUNE® (MVA-BN®) Smallpox Vaccine in Healthy, Vaccinia-naïve Subjects

Smallpox

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety, Tolerability, and Immune Response of ACAM3000 Modified Vaccinia Ankara (MVA) Smallpox Vaccine in Adults

Smallpox

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Prevenar® to Pneumo 23 in Reducing Carriage in Children

Vaccines, Pneumococcal | Vaccines, Pneumococcal Conjugate Vaccine
Bavarian Nordic

Completed

A Phase II Trial to Compare a Liquid-frozen and a Freeze-dried Formulation of IMVAMUNE (MVA-BN®) Smallpox Vaccine in Vaccinia-naïve Healthy Subjects

Smallpox

United States
National Institute of Allergy and Infectious Diseases...

Completed

Vaccinia Virus Vaccine (APSV) in Vaccinia- Naive Subjects: PILOT

Smallpox

United States
National Institute of Allergy and Infectious Diseases...

Completed

APSV in Vaccinia Naive Adults

Smallpox

United States
Bavarian Nordic

Completed

Take Rate, Immunogenicity and Safety of Elstree-BN Smallpox Vaccine in Healthy Vaccinia-Naive Subjects

Smallpox

Germany
Hangzhou Converd Co., Ltd.

Recruiting

Safety of Recombinant Human IL-21 Oncolytic Vaccinia Virus Injection（hV01) in Advanced Tumors

Advanced Solid Tumors

China
Bavarian Nordic

Completed

A Study to Evaluate Safety and Immunogenicity of One and Two Doses of IMVAMUNE® Smallpox Vaccine in 56-80 Year Old Vaccinia-experienced Subjects

Smallpox

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV Envelope Vaccine (HIVAC-1e) in Combination With a Panel of Subunit Recombinant HIV Envelope Vaccines in Vaccinia-Naive Individuals

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Randomized Trial to Evaluate the Safety and Immunogenicity of Vaccinia-HIV Envelope Recombinant Vaccine (HIVAC-1e) in Combination With Soluble Recombinant Envelope Vaccine (VaxSyn)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Phase I Safety and Immunogenicity Trial of Vaccinia-HIV Envelope Recombinant Vaccine (HIVAC-1e) in Combination With Soluble Recombinant Envelope Vaccine (gp160; VaxSyn)

HIV Infections

United States
Crucell Holland BV
National Institute of Allergy and Infectious Diseases (NIAID); Beth Israel... and other collaborators

Completed

A Phase I Study of an HIV Vaccine in Healthy, HIV Uninfected Adults (MENSCH)

Healthy

United States
Bandim Health Project
Statens Serum Institut; Research Center for Vitamins and Vaccines

Unknown

Vaccine Campaign Effects on General Hospital Admissions and Mortality Among Children (RE-CAMP)

Mortality | Children | Oral Polio Vaccine | Morbidity | Measles Vaccination | Non-specific/Heterologous Effects of Vaccines

Guinea-Bissau
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV Envelope Vaccine (HIVAC-1e) in Combination With a Panel of Subunit Recombinant HIV Envelope Vaccines

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of the Therion Recombinant Vaccinia-HIV-1 IIIB ENV/GAG/POL Vaccine (TCB-3B) and MN RGP 120/HIV-1 In Alum.

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
GeoVax, Inc.

Completed

Evaluating the Safety and Immune Response of a Prime-Boost HIV Vaccine Regimen in Healthy, HIV-Uninfected, Vaccinia-Naive Adults

HIV Infections

United States
National Eye Institute (NEI)

Completed

Evaluation and Treatment of Eye Complications of Vaccinia Vaccination

Vaccinia

United States
Bandim Health Project
Odense University Hospital; Odense Patient Data Explorative Network; Municipality...

Completed

Using BCG to Protect Senior Citizens During the COVID-19 Pandemic

Covid19 | Immunosenescence | Vaccine Preventable Disease | Morbidity | Non-specific Effects of Vaccines | Heterologous Immunity

Denmark
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to a DNA HIV Vaccine (pGA2/JS7) Boosted With a Modified Vaccinia HIV Vaccine (MVA/HIV62) in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Immuno-US

Completed

A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived HIV-1 Recombinant Envelope Glycoprotein (gp160)

HIV Infections

United States
Genelux Corporation

Completed

Safety Study of GL-ONC1, an Oncolytic Virus, in Patients With Advanced Solid Tumors

Advanced Cancers (Solid Tumors)

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Phase I/II Trial of Modified Vaccinia Virus Ankara (MVA) Vaccine Against Smallpox

Healthy

United States
Tasly Tianjin Biopharmaceutical Co., Ltd.

Unknown

Safety, Tolerability and Pharmacokinetics Characteristics of Recombinant Oncolytic Vaccinia Virus Injection T601 as a Single Drug or in Combination With Oral Flucytosine (5-FC), in Patients With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumors

China
Kenya Medical Research Institute
Merck Sharp & Dohme LLC; University of Washington

Completed

Antibody Response to Prophylactic QHPV Vaccine at 48 Months Among HIV-infected Girls and Boys

HPV Infection | HPV Vaccine | HIV-1-infection

Kenya

Clinical Trials on Vaccinia Virus Infection

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