Clinical Trials on Valvular Heart Disease in Czechia

Total 5490 results

General University Hospital, Prague

Recruiting

Lifestyle Modification in the Treatment of NAFLD.

NAFLD

Czechia
University Hospital Ostrava

Completed

Correlation of Right-left Shunt Detection in Cardioembolism Etiology in Stroke Patient.

Foramen Ovale Patent

Czech Republic
LEO Pharma

Completed

Innohep® in Elderly Patients With Impaired Renal Function Treated for Acute Deep Vein Thrombosis

Deep Vein Thrombosis

Bulgaria, Croatia, Czechia, France, Germany, Poland, Romania, Serbia, Spain
University Hospital Ostrava

Completed

Correlation Between Laboratory Markers and Origin of New Brain Ischemic Lesions After Carotid Stenting

Brain Ischemia | Carotid Stenosis | Laboratory Problem

Czech Republic
Masaryk University

Completed

Effect of Noninvasive Brain Stimulation on Hypokinetic Dysarthria in Parkinson's Disease

Parkinson Disease

Czechia
Charles University, Czech Republic

Recruiting

Reversibility of Bronchial Obstruction in Children Born Preterm

Bronchopulmonary Dysplasia | Chronic Lung Disease of Prematurity | Bronchial Hyperreactivity | Preterm Birth Complication | Chronic Lung Disease of Newborn | Bronchial Obstruction | Reversible Dilatation

Czechia
University Hospital, Motol

Completed

Nitrogen Bubble Detection After Simulated Dives in Divers With PFO and After PFO Closure

Patent Foramen Ovale

Czech Republic
Maasstad Hospital
Abbott Medical Devices

Completed

Comparison Between FFR Guided Revascularization Versus Conventional Strategy in Acute STEMI Patients With MVD. (CompareAcute)

Myocardial Infarction | Multivessel Coronary Artery Disease

Norway, Netherlands, Poland, Singapore, Germany, Czechia, Hungary, Sweden
Brno University Hospital

Active, not recruiting

Inspiratory Muscle Training and COPD

Chronic Obstructive Pulmonary Disease

Czechia
ThromboGenics

Completed

A Study to Evaluate the Safety and Efficacy of THR-317 for the Treatment of Diabetic Macular Oedema (DME)

Diabetic Retinopathy | Macular Edema

Czechia, Slovakia, Hungary
Thomayer University Hospital
Charles University, Czech Republic

Completed

Faecal Microbiota Transplantation in Irritable Bowel Syndrome (MISCEAT)

Irritable Bowel Syndrome With Diarrhea | Irritable Bowel Syndrome Mixed

Czechia
Military University Hospital, Prague
University Hospital, Motol

Recruiting

The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration

Degenerative Disc Disease | Back Pain Lower Back Chronic | Facet Joint Arthropathy | Facet Syndrome of Lumbar Spine

Czechia
Acutus Medical

Completed

Dipole Density Mapping in Supraventricular Tachycardia (DDRAMATIC-SVT)

Supraventricular Tachycardia

United Kingdom, Canada, Czechia, Belgium, Chile, Germany
ZOLL Circulation, Inc., USA

Completed

COOL-AMI EU Case Series Clinical Study

Acute Myocardial Infarction

Hungary, United Kingdom, Germany, Estonia, Poland, Serbia, Czechia, Lithuania
Faculty Hospital Kralovske Vinohrady

Completed

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Infections | Multiple Sclerosis | Autoimmune Diseases | Diabetes Mellitus, Type 1 | Rheumatoid Arthritis | Vaccine Reaction | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Down Syndrome | Atopic Dermatitis | Vitiligo | Alopecia Areata | COVID-19 Pandemic | Ankylosing Spondylitis | Lupus Erythematosus and other conditions

Czechia
General University Hospital, Prague

Recruiting

Ursodeoxycholic Acid in Patients With NAFLD - Clinical Observation (URSO)

Non-Alcoholic Fatty Liver Disease

Czechia
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
University Hospital, Bordeaux
Funding: European Commission (H2020)

Active, not recruiting

Ground-Breaking Electroporation-based Intervention for PAROXysmal Atrial Fibrillation Treatment (BEAT PAROX-AF) (BEAT PAROX-AF)

Atrial Fibrillation

France, Czechia, Austria, Germany, Belgium
Charles University, Czech Republic

Unknown

Risk Factors Associated With Calcification of the Aortic Valve

Aortic Stenosis | Aortic Sclerosis

Czech Republic
The Institute of Molecular and Translational Medicine...

Not yet recruiting

Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients

Critical Illness | Acute Respiratory Failure

Czechia
University Hospital Olomouc
Palacky University

Completed

Strip Meniscometry in Dry Eye Evaluation

Dry Eye | Dry Eye Disease

Czechia
Queen Mary University of London

Completed

BAMI. The Effect of Intracoronary Reinfusion of Bone Marrow-derived Mononuclear Cells(BM-MNC) on All Cause Mortality in Acute Myocardial Infarction (BAMI)

Myocardial Infarction | Death

Spain, Germany, Switzerland, Italy, Finland, Czechia, Belgium, Denmark, Netherlands, United Kingdom
General University Hospital, Prague

Recruiting

Molecular Markes of Fibrosis of Endometriosis and Their Use in Predicting Disease Severity (MMF)

Molecular Markers of Fibrosis of Single Types of Endometriosis and Their Use in Predicting Disease Severity

Czechia
Charles University, Czech Republic
AstraZeneca

Unknown

CHANCE - Candesartan in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

Czech Republic
Patient Organization Veronica

Recruiting

HPV DNA Self-sampling in a General Practitioner's Office. (ASTRA)

Cervical Cancer | HPV Infection | Precancerous Lesion

Czechia
Masaryk University
St. Anne's University Hospital Brno, Czech Republic

Unknown

Modulation of Cognition and Brain Connectivity by Noninvasive Brain Stimulation in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease (LUSTR)

Mild Cognitive Impairment

Czechia
Stimvia s.r.o.

Not yet recruiting

Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's Disease and Essential Tremor

Parkinson's Disease | Essential Tremor

Czechia
Military University Hospital, Prague
University Hospital, Motol

Completed

The SPINUS I Study: Spinal Fusion for a Single Level SPECT/CT Positive Lumbar Degenerative Disc Disease

Degenerative Disc Disease | Back Pain, Low

Czechia
Novartis
The TIMI Study Group

Completed

Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary Syndrome

Myocardial Ischemia | Post Acute Coronary Syndrome

Germany, Spain, United States, Belgium, Canada, Czech Republic, Hungary, Netherlands, Poland, Russian Federation, Sweden
Laboratoires URGO

Unknown

Assessment of the Efficacy and Safety of a New Medical Device in the Local Treatment of Diabetic Foot Ulcers (DISCOVERY)

Diabetic Foot Ulcer

Czechia, France, Italy, Poland, Spain, United Kingdom
Charles University, Czech Republic

Recruiting

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents

Pneumonia | Cough | Asthma | Asthma in Children | Dyspnea | Recurrent Respiratory Tract Infections | Shortness of Breath | Wheezing | Mucus; Plug | Lower Respiratory Tract and Lung Infections | Chest Tightness

Czechia
Oncopeptides AB

Terminated

PK of Melphalan During Treatment With Melflufen and Dexamethasone in Patients With RRMM and Impaired Renal Function (BRIDGE)

Multiple Myeloma | Renal Impairment

Greece, Czechia, Poland
Medical University of Vienna

Terminated

Coronary Bypass Surgery Trial: Complete Arterial Revascularization and Conventional Coronary Artery Surgery

Coronary Artery Disease

Germany, Austria, Czech Republic, Norway, Poland, Spain, Sweden
Masaryk Memorial Cancer Institute
Masaryk University

Recruiting

Pancreatic Cancer Screening in a Population at High Risk (ScrePan)

Pancreatic Ductal Adenocarcinoma | Pancreatitis, Chronic | Hereditary Diseases

Czechia
Nordic Pharma SAS

Terminated

Clinical Study Comparing the New Immunosuppressive Drug Gusperimus With the Conventional Treatment in Wegener's Granulomatosis (SPARROW)

Wegeners Granulomatosis

Czech Republic
Charles University, Czech Republic
Faculty Hospital Kralovske Vinohrady

Unknown

Early Mobilization and Intensive Rehabilitation in the Critically Ill (EMIR)

Critical Illness

Czechia
Boehringer Ingelheim

Completed

Efficacy and Tolerability CVI (A 12-week, Double-blind, Randomised, Placebo-controlled, Multicentre Trial (CVI)

Venous Insufficiency

Germany, Austria, Czech Republic
Boehringer Ingelheim

Completed

Patient Convenience Study (RE-SONANCE)

Stroke | Atrial Fibrillation

Austria, Czechia, Hungary, Israel, Romania, Russian Federation, Slovenia, Poland, Estonia, Bulgaria, Latvia, Serbia
Biotest
PRA Health Sciences

Completed

Adjusted Fibrinogen Replacement Strategy (AdFIrst)

Bleeding Disorder | Hypofibrinogenemia; Acquired

Belgium, Czechia, Germany, Poland, Spain, Switzerland, United Kingdom
Niguarda Hospital

Recruiting

Ischemic And Bleeding Risk Assessment After TAVR (FOCUS ONE)

Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement

Italy, Belgium, Czechia, Chile, Spain
Bayer

Completed

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY 1142524 in Patients After Acute Myocardial Infarction With Left-ventricular Dysfunction (CHIARA MIA 2)

Myocardial Infarction

Spain, Germany, Czechia, Israel, Italy
University Hospital Ostrava
Palacky University

Completed

SONOlysis in Prevention of Brain Infarctions dUring Carotid Stenting and caroTid EndaRterectomy (SONOBUSTER)

Internal Carotid Artery Stenosis

Czech Republic
Masaryk University
St. Anne's University Hospital Brno, Czech Republic

Not yet recruiting

Noninvasive Temporal Interference Stimulation: Modulating Associative Memory by Targeting Deep-brain Targets (Deep-HiPs)

Alzheimer Disease | Healthy Aging | Mild Cognitive Impairment | Memory Disorders in Old Age

Czechia
University Hospital, Bordeaux
Horizon 2020 - European Commission

Recruiting

Ground-Breaking Electroporation-based Intervention for PERSistent Atrial Fibrillation Treatment (BEAT PERS-AF) (BEAT PERS-AF)

Atrial Fibrillation

Austria, France, Czechia, Belgium, Germany
National Institute of Cardiology, Warsaw, Poland

Recruiting

Drug-coated Balloon in de Novo Chronic Total Occlusions (CTO-DENOVO)

Coronary Artery Disease | Total Occlusion of Coronary Artery

Spain, France, Hungary, Czechia, Poland, Austria, Croatia, Germany, Israel, Italy, Romania
Biosense Webster, Inc.

Completed

RENABLATE-II Feasibility Study of Catheter Based Renal Denervation to Treat Resistant Hypertension - 157 (RENABLATE-II)

Hypertension, Renal

Czech Republic, Italy, New Zealand, Spain
Rottapharm Biotech

Completed

A Study of the EP4 Antagonist CR6086 in Combination With Methotrexate, in DMARD-naïve Patients With Early Rheumatoid Arthritis

Rheumatoid Arthritis, DMARD-naive and Early Disease Patients

Czechia
CoreAalst BV
Abbott Medical Devices

Recruiting

FAME II-10-year Follow-Up (FAME2-10yFU)

Coronary Artery Disease

United States, Netherlands, Denmark, United Kingdom, Sweden, Belgium, Canada, Czechia, France, Germany, Hungary, Italy, Serbia
Abbott Medical Devices

Completed

Substrate Modification in Stable Ventricular Tachycardia in Addition to Implantable Cardioverter Defibrillator (ICD) Therapy (VTACH)

Coronary Artery Disease | Ventricular Tachycardia | Left Ventricular Dysfunction

Germany, Switzerland, Czechia, Denmark
CeleCor Therapeutics

Recruiting

A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI (CELEBRATE)

ST-elevation Myocardial Infarction (STEMI)

Netherlands, Canada, Czechia, France, Hungary, Romania

Clinical Trials on Valvular Heart Disease in Czechia

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