Clinical Trials on Valvular Heart Surgery

Total 73094 results

West China Hospital

Completed

Characteristics, Treatment, and Economic Burden of Patients With CVD,CKD or at High Cardiovascular Risk

Diabetes | Chronic Kidney Diseases | Cardiovascular Abnormalities

China
Rennes University Hospital
Ministry of Health, France

Completed

Quantification of Liver Iron Overload and Steatosis Using Magnetic Resonance Imaging (SURFER)

Hepatitis B | Hepatitis C | Iron Overload | Metabolic Syndrome X | Alcohol Abuse

France, Spain
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Prevalence of Autistic Spectrum Disorder (ASD) in Children With Haemophilia

Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Social Communication Disorder | Haemophilia
University College, London

Unknown

TTP and aHUS in Complicated Pregnancies

Thrombotic Microangiopathies | Thrombotic Thrombocytopenic Purpura | Thrombocytopenia | Pre-Eclampsia | HELLP Syndrome | Stillbirth | Atypical Hemolytic Uremic Syndrome | IUGR

United Kingdom
National Institute of Neurological Disorders and...

Completed

A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia

Multiple Sclerosis | Parkinson Disease | Chronic Dysphagia

United States
Maria Sklodowska-Curie National Research Institute...

Recruiting

Radiotherapy With Hyperthermia in Recurrent and Radiation-Induced Sarcomas (HOT)

Recurrent Soft Tissue Sarcoma | Recurrent Sarcoma | Radiation Induced Neoplasms | Radiation-Induced Cancer

Poland
University Hospital Tuebingen

Completed

Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer (HT01)

Hyperthermia | Rectal Cancer | Locally Advanced Rectal Cancer | Hyperthermic Radiochemotherapy | Hyperthermic Chemoradiotherapy | Deep Regional Hyperthermia

Germany
Chang Gung Memorial Hospital

Unknown

Registry of Febrile Neutropenia and Invasive Fungal Infections

Febrile Neutropenia | Hematological Disease | Fungal Infections

Taiwan
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Terminated

S9624 Ifosfamide in Treating Patients With Meningeal Tumors

Chondrosarcoma | Adult Rhabdomyosarcoma | Adult Fibrosarcoma | Adult Leiomyosarcoma | Adult Malignant Meningioma | Adult Brain Malignant Hemangiopericytoma

United States, Australia, Peru, Puerto Rico
Regeneron Pharmaceuticals

Completed

Rilonacept for Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS)

Genetic Diseases, Inborn | Familial Cold Autoinflammatory Syndrome (FCAS) | Familial Cold Urticaria | Muckle-Wells Syndrome (MWS)

United States
GT Medical Technologies, Inc.

Recruiting

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

Brain Tumor | Brain Tumor, Recurrent | Brain Tumor, Primary | Brain Tumor - Metastatic | Brain Tumor, Adult: Glioblastoma | Brain Tumor, Adult Meningioma

United States
National Cancer Institute (NCI)

Recruiting

Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

Ependymoma | Medulloblastoma | Pineal Region Tumors | Choroid Plexus Tumors | Atypical/Malignant Meningioma

United States
University of Texas Southwestern Medical Center
Texas A&M University; University of Texas Rio Grande Valley

Completed

PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia

Mild Cognitive Impairment (MCI) | Alzheimer Disease | Lewy Body Dementia (LBD) | Frontotemporal Degeneration (FTD) | Vascular Contributions to Cognitive Impairment and Dementia (VCID) | Mixed Etiology Dementias (MED)

United States
St. Jude Children's Research Hospital

Recruiting

Familial Investigations of Childhood Cancer Predisposition (SJFAMILY)

Pancreatic Cancer | Hodgkin Lymphoma | Lynch Syndrome | Tuberous Sclerosis | Fanconi Anemia | AML | Non Hodgkin Lymphoma | Familial Adenomatous Polyposis | Acute Leukemia | Nevoid Basal Cell Carcinoma Syndrome | Neurofibromatosis Type 1 | Neuroblastoma | Retinoblastoma | MDS | Rhabdomyosarcoma | Von Hippel-Lindau Disease | Adrenocortical Carcinoma and other conditions

United States
Wake Forest University Health Sciences

Completed

Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors

Glioblastoma Multiforme | Anaplastic Astrocytoma | Brain Neoplasms, Benign | Brain Neoplasms, Malignant | Malignant Meningioma

United States
Schrödinger, Inc.

Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

Follicular Lymphoma | Splenic Marginal Zone Lymphoma | Burkitt Lymphoma | Plasmablastic Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Non Hodgkin Lymphoma | Primary Effusion Lymphoma | DLBCL | High-grade B-cell Lymphoma | Primary Mediastinal... and other conditions

United States, Moldova, Republic of
Masonic Cancer Center, University of Minnesota

Recruiting

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Follicular Lymphoma | Multiple Myeloma | Myelofibrosis | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | Mantle-Cell Lymphoma | Diffuse Large B Cell Lymphoma | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Myelodysplasia | Acute Myeloid Leukemia... and other conditions

United States
Masonic Cancer Center, University of Minnesota

Withdrawn

T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies

Follicular Lymphoma | Acute Myeloid Leukemia | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Acute Lymphocytic Leukemia | Mantle-Cell Lymphoma | Hematologic Malignancy | Small Lymphocytic Lymphoma | Burkitt's Lymphoma | Marginal Zone B-cell Lymphoma | Chronic Myeloproliferative... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Rituximab and Dexamethasone in Treating Patients With Low-Grade Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenstrom Macroglobulinemia | Cutaneous B-cell Non-Hodgkin Lymphoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Iodine I 131 Tositumomab and Fludarabine Phosphate in Treating Older Patients Who Are Undergoing an Autologous or Syngeneic Stem Cell Transplant for Relapsed or Refractory Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Massachusetts General Hospital

Recruiting

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders (BMT)

Autoimmune Diseases | Multiple Myeloma | Hodgkin Disease | AL Amyloidosis | Myelofibrosis | Chronic Kidney Disease | Sickle Cell Anemia | Thalassemia | Aplastic Anemia | Chronic Lymphocytic Leukemia (CLL) | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Non-Hodgkin... and other conditions

United States
Kantonsspital Winterthur KSW
Luzerner Kantonsspital

Not yet recruiting

Skin Cancer and Hyperthermia and Radiotherapy (SAHARA)

Basal Cell Carcinoma | Non-melanoma Skin Cancer | Squamous Cell Carcinoma Skin

Switzerland
University of Erlangen-Nürnberg Medical School

Recruiting

Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia (HyBla_RCT)

Bladder Cancer

Germany
Lakehead University

Completed

Diphenhydramine and Sweating (BENEXE2022)

Hyperthermia | Allergic Rhinitis | Diphenhydramine Causing Adverse Effects in Therapeutic Use | Sweating

Canada
The Cleveland Clinic

Completed

Rilonacept for Treatment of Familial Mediterranean Fever (FMF)

Familial Mediterranean Fever

United States
Capital Medical University

Terminated

Combination of Immunotherapy and Hyperthermia in Advanced Malignant Mesothelioma

Cancer | Mesothelioma, Malignant

China
Baskent University

Completed

Efficacy of Ultrasound Versus Short Wave Diathermy in the Treatment of a Slipped Disc of the Lower Back

Low Back Pain, Mechanical | Radiculopathy | Herniated Disk Lumbar

Turkey
Fred Hutchinson Cancer Center
medac GmbH

Recruiting

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Acute Myeloid Leukemia | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mantle Cell Lymphoma | Lymphoplasmacytic Lymphoma | Anaplastic Large Cell Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditions

United States
Fred Hutchinson Cancer Center
Mustang Bio

Active, not recruiting

A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic... and other conditions

United States
Mayo Clinic

Recruiting

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
National Cancer Institute (NCI)

Active, not recruiting

Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis

Kaposi Sarcoma | Primary Effusion Lymphoma | KSHV Associated Multicentric Castleman Disease | IL-6 Related KSHV Associated Cytokine Syndrome

United States
National Cancer Institute (NCI)

Completed

T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer

Melanoma | Breast Cancer | Non-Small Cell Lung Cancer | Meningioma | Hepatocellular Cancer

United States
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Recurrent Meningioma

Recurrent Adult Brain Tumor | Adult Grade I Meningioma | Adult Grade II Meningioma | Adult Meningeal Hemangiopericytoma | Adult Meningioma | Adult Grade III Meningioma

United States
Institut Claudius Regaud

Recruiting

Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group (MIRAS)

Soft Tissue Sarcoma | Perivascular Epithelioid Cell Neoplasms | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Desmoplastic Small Round Cell Tumor | Clear Cell Sarcoma | Sclerosing Epithelioid Fibrosarcoma | Low Grade Fibromyxoid Sarcoma | Malignant Solitary Fibrous Tumors | Epithelioid Hemangioendothelioma

France
Mayo Clinic

Recruiting

Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
National Institute of Cancerología
Instituto Nacional de Enfermedades Respiratorias

Completed

Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.

Kaposi Sarcoma | Human Immunodeficiency Virus | Immune Reconstitution Syndrome

Mexico
The University of Texas Health Science Center at...
National Heart, Lung, and Blood Institute (NHLBI)

Completed

KSHV Infection in Blood Donors From Texas

HIV Infections | Acquired Immunodeficiency Syndrome | Sarcoma, Kaposi | Blood Transfusion | Blood Donors | Herpesvirus, Kaposi Sarcoma-Associated
University of Erlangen-Nürnberg Medical School

Unknown

Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy (HYCAN)

Anal Carcinoma

Germany
University of South Carolina
National Institute of Nursing Research (NINR)

Recruiting

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

Cardiovascular Diseases | Stroke | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Disease | SARS- CoV-2

United States
Incyte Corporation

Recruiting

Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms (LIMBER)

Myelofibrosis | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome | Relapsed or Refractory Primary Myelofibrosis | Secondary Myelofibrosis (Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis) | ET...

United States, Spain, Japan, Italy, Finland, United Kingdom, Canada
Association pour le Développement et l'Organisation...

Recruiting

Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases (DVD)

Neuromuscular Diseases | Interstitial Lung Disease | Acute Respiratory Failure | Obesity Hypoventilation Syndrome | Acute Exacerbation of COPD | Acute Exacerbation of Bronchiectasis | Acute Exacerbation of Asthma

France
National Human Genome Research Institute (NHGRI)

Recruiting

Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome

Hermansky-Pudlak Syndrome (HPS)

United States
Sparrow Pharmaceuticals

Active, not recruiting

SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome (RESCUE)

Cortisol; Hypersecretion | Cortisol Overproduction | Cushing's Syndrome I | Cushing Disease Due to Increased ACTH Secretion | Cortisol Excess | Ectopic ACTH Secretion

United States, Bulgaria, Romania
National Cancer Institute (NCI)

Terminated

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

Carcinoma, Renal Cell | Gastrointestinal Stromal Tumors | Pheochromocytoma | Paraganglioma | Renal Neoplasms

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Osilodrostat in Cushing's Syndrome

Cushing's Syndrome | Ectopic Corticotropin Syndrome | Adrenal Adenoma | Adrenal Carcinoma | AIMAH | PPNAD

Japan
Centre Hospitalier Universitaire, Amiens

Terminated

Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies (GREFEXII)

Stroke | Parkinson Disease | Alzheimer Disease | Traumatic Brain Injury | Huntington Disease | Frontal Dementia

France
Faculty of Medicine, Tarumanagara University
Hana Old Age Home

Unknown

Determinants of Cognitive Impairment Among Geriatrics

Depression | Hypertension | Obesity | Diabetes | Osteoarthritis | Cognitive Impairment | Dyslipidemias | Dementia | Mobility Limitation | Hearing Impairment | Vision Impairment and Blindness | Central Obesity

Indonesia
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Withdrawn

Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer

Sarcoma | Pain | Lymphoma | Ovarian Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Cachexia | Melanoma (Skin)
Duke University

Completed

Melphalan in Patients With Neoplastic Meningitis

Lymphoma | Leukemia | Ovarian Cancer | Brain and Central Nervous System Tumors | Extragonadal Germ Cell Tumor

United States
University of Kansas

Completed

A Randomized Exercise Trial for Wheelchair Users

Stroke | Multiple Sclerosis | Cerebral Palsy | Arthritis | Muscular Dystrophy | Amputation | Spinal Cord Injury | Spina Bifida

United States

Clinical Trials on Valvular Heart Surgery

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Hong Kong

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations