Clinical Trials on Ventricular Outflow Obstruction

Total 13129 results

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Completed

Is Monocyte/HDL Ratio a Predictor of Mortality in Aortic Valve Surgery

Inflammation | Aortic Valve Stenosis | HDL

Turkey
Klinik für Kardiologie, Pneumologie und Angiologie

Completed

Virtual Reality Assisted Conscious Sedation During TAVI (TAVI_VR)

Pain | Anxiety | Severe Aortic Valve Stenosis

Germany
Edwards Lifesciences
Pacific Clinical Research Group

Completed

The SOLACE-AU Clinical Trial (SOLACE-AU)

Severe, Symptomatic Aortic Stenosis

Australia
Oslo University Hospital

Completed

Comparison of Blood and Crystalloid Cardioplegia

Aortic Stenosis | Myocardial Protection

Norway
University of Göttingen

Recruiting

Exercise CMR in (p)LF-LG AS

Aortic Stenosis, Severe

Germany
University Medical Centre Ljubljana

Not yet recruiting

Conventional Versus Left Bundle Branch Pacing in TAVI

Heart Failure | Aortic Valve Stenosis | Pacemaker-Induced Cardiomyopathy | Transcatheter Aortic Valve Implantation

Slovenia
Ottawa Heart Institute Research Corporation

Recruiting

Effect of Colchicine on the Progression of Aortic Valve Stenosis - A Pilot Study (COPAS-Pilot)

Inflammation | Aortic Stenosis

Canada
Romanian Society of Cardiology

Recruiting

Romanian National Registry of Outcomes After Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis - RO-TAVI (RO-TAVI)

Aortic Valve Stenosis | Aortic Stenosis Symptomatic

Romania
Medtronic Cardiovascular

Active, not recruiting

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). (SURTAVI)

Severe Aortic Stenosis

United States, Netherlands, Canada, Spain, Denmark, United Kingdom, Switzerland, Germany, Sweden
Boston Scientific Corporation

Active, not recruiting

ACURATE neo2™ Post Market Clinical Follow up Study

Aortic Valve Stenosis | Aortic Diseases | Aortic Valve Calcification

Netherlands, Denmark, United Kingdom, Spain, Italy, Switzerland, Sweden, Germany
Edwards Lifesciences

Completed

Surgical Treatment of Aortic Stenosis With a Next Generation Surgical Aortic Valve (TRITON)

Aortic Valve Stenosis | Aortic Valve Stenosis With Insufficiency

Austria, Germany
Norwegian University of Science and Technology
Oslo University Hospital; St. Olavs Hospital

Completed

Ultrasonic Markers for Myocardial Fibrosis and Prognosis in Aortic Stenosis

Myocardial Fibrosis | Aortic Valve Stenosis

Norway
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2011-03) (2011-03)

Aortic Stenosis Symptomatic

Germany, Brazil
Medtronic Cardiovascular

Completed

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

Severe Aortic Stenosis

United States
Abbott Medical Devices

Completed

First in Human Experience of the St. Jude Medical TAVI Valve and Delivery System (SJM TAVI FIH)

Symptomatic Aortic Stenosis

United Kingdom
Abbott Medical Devices

Completed

Portico TAVI Implant With Transfemoral Delivery System

Symptomatic Aortic Stenosis

United Kingdom, Germany, Netherlands, Denmark, Australia
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis:CE-approval Cohort

Symptomatic Aortic Stenosis

Germany, Japan, Brazil
Symetis SA

Completed

Feasibility Trial on ACURATE™ Transapical Implantation in Patients With Severe Symptomatic Aortic Stenosis (2009-01) (TA-FIM)

Aortic Stenosis Symptomatic

Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...
Edwards Lifesciences

Unknown

Feasibility of Continuous Noninvasive Finger Arterial Blood Pressure Measurement for Detection and Staging of Aortic Stenosis (COaRt)

Aortic Stenosis, Calcific

Netherlands
Boston Children's Hospital

Withdrawn

Systemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent Placement

Peripheral Pulmonary Stenosis | In-stent Stenosis

United States
University College, London

Completed

Regression of Myocardial Fibrosis After Aortic Valve Replacement (RELIEF-AS)

Aortic Stenosis

United Kingdom
HLT Inc.

Withdrawn

HLT transfemOral Replacement of aortIc Valve Via transcatherteriZatiON CANADA (HORIZON CANADA)

Severe Aortic Stenosis

Canada
Competence Network for Congenital Heart Defects
German Federal Ministry of Education and Research

Completed

Pulmonary Arteriopathy-Diagnostics and Therapy

Pulmonary Stenosis

Germany
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Balloon Valvuloplasty Registry

Heart Diseases | Aortic Valve Stenosis | Mitral Valve Stenosis
Novartis Pharmaceuticals

Recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Aortic Stenosis

Switzerland, Canada, Israel, United States, United Kingdom
Cardio Med Medical Center
George Emil Palade University of Medicine, Pharmacy, Sciences and Technology... and other collaborators

Recruiting

Feasibility of 3D Printed Models of Aortic Stenosis in Guiding TAVI Procedure (3DP-FAST)

Aortic Stenosis | Aortic Valve Disease | Valvular Cardiomyopathy

Romania
Matteo Montorfano

Recruiting

Microvascular Function in Patients Undergoing Transcatheter Aortic Valve Implant (TAVI) for Severe Symptomatic Aortic Stenosis: Association With Myocardial Fibrosis

Severe Symptomatic Aortic Stenosis

Italy
Odense University Hospital
University of Southern Denmark; Region of Southern Denmark

Recruiting

Diagnostic Impact of Low-dose Dobutamine Echocardiography in Low-flow Low-gradient Aortic Stenosis (DALLAS)

Aortic Valve Stenosis | Valvular Heart Disease | Valvular Stenosis

Denmark
The Cleveland Clinic

Recruiting

Comparative Imaging Assessment of Valvular Heart Disease

Aortic Stenosis | Aortic Regurgitation | Valve Heart Disease

United States
Universita di Verona

Recruiting

Functional Assessment In TAVI: FAITAVI (FAITAVI)

Coronary Artery Disease | Aortic Valve Stenosis

Italy
Christine Henri

Recruiting

The Role of Cardiac Mechanics, Biomarkers and Frailty in Aortic Stenosis (SCRABLES)

Heart Failure | Aortic Stenosis

Canada
Edwards Lifesciences

Active, not recruiting

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis (EARLY TAVR)

Heart Diseases | Aortic Stenosis, Severe

United States, Canada
The Royal Wolverhampton Hospitals NHS Trust

Completed

Novel Echocardiographic and Invasive Haemodynamic Measurements in the Assessment of Patients Low Flow Low Gradient Aortic Stenosis Undergoing TAVI (LFLG)

Cardiovascular Abnormalities

United Kingdom
Nantes University Hospital

Completed

Change in Coronary Microcirculation and FFR After TAVI in Patients With Cardiovascular Comorbidities

Severe Symptomatic Aortic Stenosis

France
JC Medical, Inc.

Completed

Safety & Efficacy of the J-Valve Ausper System in Patients With Severe Aortic Stenosis and/or Aortic Regurgitation

Aortic Valve Disease

China
Campus Bad Neustadt
Institut für Pharmakologie und Präventive Medizin; Edwards Lifesciences; Software...

Completed

Registry to Gather Long-time Results After Surgical Aortic Valve Replacement With a "Rapid Deployment Aortic Valve Prothesis (Edwards Intuity) Combined With Bypss Surgery (CABG) (INCA)

Coronary Artery Disease | Aortic Valve Stenosis

Germany
Instituto Nacional de Cardiologia Ignacio Chavez

Completed

Analysis and Comparative Evaluation of Aortic Calcium by Computed Tomography and Histopathology in Patients With Aortic Stenosis

Aortic Valve Stenosis | Aortic Calcification Valve

Mexico
University of California, San Francisco
Eko Devices, Inc.

Completed

Phono- and Electrocardiogram Assisted Detection of Valvular Disease (PEA-Valve)

Aortic Valve Stenosis | Mitral Regurgitation | Heart Murmurs | Valvular Heart Disease

United States
St. Antonius Hospital

Completed

Patient Reported Health-Related Quality of Life After Limited Access and Conventional Aortic Valve Replacement (LIAR)

Quality of Life | Aortic Valve Stenosis | Limited Access Aortic Valve Replacement

Netherlands
University of Pennsylvania

Completed

Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS) (PULSE-AS)

Aortic Valve Stenosis

United States
Kobe University

Unknown

Evaluation of Fractional Flow Reserve Calculated by Computed Tomography Coronary Angiography in Patients Undergoing TAVR (FORTUNA)

Coronary Artery Disease | Aortic Valve Stenosis
Centre de Recherche de l'Institut Universitaire...

Completed

Erythropoietin + Iron Therapy for Anemic Patients Undergoing Aortic Valve Replacement (EPICURE)

Anemia | Aortic Stenosis

Canada
The Society of Thoracic Surgeons
American College of Cardiology

Completed

Alternative Access Approaches for Transcatheter Aortic Valve Replace (TAVR) in Inoperable Patients With Aortic Stenosis (Inop AA)

Severe Symptomatic Aortic Stenosis
Hungarian Institute of Cardiology
Semmelweis University

Unknown

Frailty and Cognitive Function Assessment of TAVI Patients

Quality of Life | Aortic Valve Stenosis | Heart Valve Disease

Hungary
Kaplan Medical Center

Unknown

Endothelial Progenitors in Aortic Stenosis: Association With Aortic Stenosis Progression and Severity

Aortic Stenosis | Cardiac Death

Israel
Assiut University

Recruiting

Outcome of Balloon Pulmonary Valvuloplasty in Patients With Congenital Pulmonary Stenosis in Terms of Reverse Right Ventricular Remodelling and Functional Exercise Capacity

Congenital Heart Disease | Pulmonary Valve Stenoses

Egypt
Barts & The London NHS Trust
Imperial College London

Not yet recruiting

RESTORE-TAVI Pilot

Aortic Stenosis | Frailty
Guy's and St Thomas' NHS Foundation Trust
King's College London

Not yet recruiting

Outcome Prediction in Patients With Aortic Stenosis After TAVI (PREDICT-TAVI)

Aortic Stenosis, Severe

United Kingdom
Insel Gruppe AG, University Hospital Bern

Not yet recruiting

Involvement of the Gut Microbiota in Calcified Aortic Stenosis (Gut-CAS)

Aortic Stenosis | Gastrointestinal Microbiome | Metabolomics
University Medical Center Goettingen

Recruiting

Effect of Antifibrotic Therapy on Regression of Myocardial Fibrosis After Transcatheter Aortic Valve Implantation (TAVI) in Aortic Stenosis Patients With High Fibrotic Burden (Reduce-MFA)

Aortic Stenosis, Severe

Germany

Clinical Trials on Ventricular Outflow Obstruction

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