Clinical Trials on Vertebral Metastasis

Total 13756 results

National Cancer Institute (NCI)

Terminated

Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer

Triple-Negative Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7 | Advanced Breast Carcinoma | Metastatic Breast Carcinoma

United States
Immune System Key Ltd

Withdrawn

Safety and Efficacy of IV Nerofe™ Followed by Doxorubicin, In Metastatic Ovarian Cancer and Triple Negative Breast Cancer

Triple Negative Breast Cancer | Metastatic Ovarian Cancer

Israel
National Cancer Institute (NCI)

Completed

Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Melanoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
Ontario Clinical Oncology Group (OCOG)
Novartis Pharmaceuticals

Completed

A Phase II Study of Dovitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary Glands (DOVE)

Recurrent Adenoid Cystic Carcinoma of the Salivary Glands | Metastatic Adenoid Cystic Carcinoma of the Salivary Glands | Salivary Gland Cancers | ACC

Canada
Hadassah Medical Organization

Completed

Activated Allogeneic Lymphocytes for Induction Graft Versus Tumor Effect in Metastatic Solid Tumors (rIL-2(LAK))

Metastatic Breast Cancer | Gastrointestinal Cancer | Renal Cell Cancer | Malignant Melanoma

Israel
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Isolated Hepatic Perfusion With Melphalan in Treating Patients With Primary Unresectable Liver Cancer or Liver Metastases

Colorectal Cancer | Metastatic Cancer | Liver Cancer | Neuroendocrine Carcinoma | Islet Cell Tumor

United States
Mayo Clinic

Recruiting

Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the Penis

Stage IV Penile Cancer AJCC v8 | Stage III Penile Cancer AJCC v8 | Metastatic Penile Squamous Cell Carcinoma | Unresectable Penile Squamous Cell Carcinoma

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) for Recurrent, Metastatic, or Unresectable HER2-Positive Salivary Gland Cancer

Recurrent Salivary Gland Carcinoma | Stage III Major Salivary Gland Cancer AJCC v8 | Stage IV Major Salivary Gland Cancer AJCC v8 | Metastatic Salivary Gland Carcinoma | Unresectable Salivary Gland Carcinoma

United States
OncoResponse, Inc.

Recruiting

A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

Melanoma | Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Solid Tumor | Leiomyosarcoma | Head and Neck Squamous Cell Carcinoma | Liposarcoma | Malignant Neoplasm | Tumor, Solid

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

Metastatic Urothelial Carcinoma | Stage III Bladder Cancer AJCC v8 | Stage IV Bladder Cancer AJCC v8 | Locally Advanced Urothelial Carcinoma

United States, Canada
M.D. Anderson Cancer Center

Active, not recruiting

Sitravatinib and Nivolumab for the Treatment of Metastatic or Advanced Clear Cell Renal Cell Cancer

Metastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8

United States
MacroGenics

Active, not recruiting

MGD019 DART® Protein in Unresectable/Metastatic Cancer

Colorectal Cancer | Advanced Cancer | Prostate Cancer Metastatic | Cutaneous Melanoma | Solid Tumor, Adult | Squamous Cell Non Small Cell Lung Cancer

United States, Spain, Bulgaria, Poland, Ukraine
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer

Gastric Adenocarcinoma | Gastric Squamous Cell Carcinoma | Gastroesophageal Junction Adenocarcinoma | Metastatic Malignant Neoplasm in the Stomach | Stage IV Esophageal Adenocarcinoma AJCC v7 | Stage IV Esophageal Squamous Cell Carcinoma AJCC v7

United States
National Cancer Institute (NCI)

Completed

Nivolumab, Cabozantinib S-Malate, and Ipilimumab in Treating Patients With Recurrent Stage IV Non-small Cell Lung Cancer

Metastatic Lung Non-Squamous Non-Small Cell Carcinoma | Recurrent Lung Non-Squamous Non-Small Cell Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7

United States
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer

Clear Cell Renal Cell Carcinoma | Metastatic Renal Cell Cancer | Recurrent Renal Cell Carcinoma | Stage IV Renal Cell Cancer

United States
xCures

Terminated

Biomarker Research Study for Patients With FGFR-Mutant Bladder Cancer Receiving Erdafitinib

Transitional Cell Carcinoma | Bladder Cancer | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | FGFR2 Gene Mutation | FGFR3 Gene Mutation | FGFR2 Amplification | Bladder Urothelial Carcinoma | Locally Advanced Urothelial Carcinoma | Refractory Bladder Carcinoma | Refractory Bladder Urothelial Carcinoma and other conditions

United States
Philogen S.p.A.

Completed

Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients

Breast Cancer | Solid Tumor | Metastatic Melanoma | Non-small Cell Lung Cancer (NSCLC)

Italy
Genzyme, a Sanofi Company
Worldwide Clinical Trials

Completed

Observational Study to Evaluate Vandetanib in RET -/+ Patients With Metastatic Medullary Thyroid Cancer (Caprelsa104)

Symptomatic, Aggressive, Sporadic, Unresectable, Locally | Advanced/Metastatic Medullary Thyroid Cancer (MTC)

Belgium, Italy, Netherlands, Spain, France, Germany, United Kingdom, Luxembourg
Celldex Therapeutics

Terminated

A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma

Kidney Neoplasms | Metastatic Renal Cell Carcinoma | Ovarian Clear Cell Carcinoma | Papillary Renal Cell Carcinoma | Renal Cell Carcinoma (RCC) | Clear-cell Renal Cell Carcinoma

United States
Azienda Ospedaliera Città della Salute e della...

Completed

Identification of In-hospital Patients in Need of Palliative Care Using a New Simplified Screening Tool (SST2017)

Chronic Heart Failure | Metastatic Cancer | Chronic Respiratory Failure | Chronic Liver Failure | Chronic Renal Failure | Locally Advanced Cancer

Italy
Peregrine Pharmaceuticals

Completed

Phase 3 Study of Bavituximab Plus Docetaxel Versus Docetaxel Alone in Patients With Late-stage Non-squamous Non-small-cell Lung Cancer (SUNRISE)

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Non-Small-Cell Lung Carcinoma | Non-Small-Cell Lung Cancer Stage IIIB | Non-Small-Cell Lung Cancer Stage IV | Non-Small-Cell Lung Cancer Metastatic

United States, Australia, Belgium, France, Germany, Greece, Hungary, Italy, Korea, Republic of, Romania, Russian Federation, Spain, Taiwan, Ukraine
University of Michigan Rogel Cancer Center

Terminated

Lapatinib (GW572016) for Metastatic or Recurrent Squamous Cell Carcinoma Esophagus

Metastatic or Recurrent Squamous Cell Carcinoma of the Esophagus

United States
Nurix Therapeutics, Inc.

Recruiting

A Study of NX-1607 in Adults With Advanced Malignancies

Cervical Cancer | Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Non-small Cell Lung Cancer (NSCLC) | Metastatic Urothelial Carcinoma | Ovarian Cancer, Epithelial | Metastatic Castration-resistant Prostate Cancer (mCRPC) | Triple Negative Breast Cancer (TNBC) | Malignant Pleural Mesothelioma... and other conditions

United States, United Kingdom
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Cancer and Blood Pressure Management, CARISMA Study

Metastatic Renal Cell Carcinoma | Chronic Kidney Disease | Stage IV Renal Cell Cancer AJCC v8 | Cardiovascular Disorder | Metastatic Thyroid Gland Medullary Carcinoma | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVB Thyroid Gland... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer

Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant... and other conditions

United States
bluebird bio
Center for International Blood and Marrow Transplant Research

Recruiting

A Study of Participants With Cerebral Adrenoleukodystrophy (CALD) Treated With Elivaldogene Autotemcel (Stargazer)

Cerebral Adrenoleukodystrophy (CALD)

United States
Sklifosovsky Institute of Emergency Care

Recruiting

Intraoperative Brain Shift Calculation Study (BRASH)

Arteriovenous Malformations | Tumor, Brain | Cavernoma | Intracerebral Hematoma

Russian Federation
Masonic Cancer Center, University of Minnesota

Recruiting

Adrenoleukodystrophy National Registry Study

Cerebral Adrenoleukodystrophy | Adrenoleukodystrophy | ALD (Adrenoleukodystrophy)

United States
Amicus Therapeutics
Engage Health Inc.

Completed

Understanding Fabry Disease Therapy Choices Through the Eyes of the Patients

Fabry Disease

United States
Grand Valley State University

Active, not recruiting

Pediatric Powered Wheelchair Standing Devices: An Exploratory Study

Cerebral Palsy | Spinal Cord Injuries | Spinal Muscular Atrophy | Genetic Disease | Spina Bifida | Development Delay

United States
Tisento Therapeutics
Children's Hospital of Philadelphia

Terminated

Phase 2a Study of IW-6463 in Adults Diagnosed With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS)

MELAS

United States
Stanford University
National Cancer Institute (NCI); Harvard University

Completed

GoalKeeper: Intelligent Information Sharing for Children With Medical Complexity (GoalKeeper)

Cerebral Palsy | Childhood Cancer | Congenital Heart Disease | Chronic Lung Disease | Congenital Metabolic Disorder | Gastrostomy

United States
University Hospital, Bordeaux

Completed

Prevalence of Fabry's Disease in a Population of Patients With Chronic Pain (DOUFABIS)

Chronic Pain | Fabry's Disease

France
Rush University Medical Center
Icahn School of Medicine at Mount Sinai

Withdrawn

Telerobotic Ultrasound for Carotid Imaging - Feasibility Study

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Coronary Artery Disease | Stroke | Cerebrovascular Disorders | Coronary Disease | Arteriosclerosis | Arterial Occlusive Diseases | Cardiovascular Disease | Atherosclerosis | Peripheral Vascular Disease | Cerebral Infarction | Coronary Arteriosclerosis | Cerebrovascular... and other conditions
The University of Hong Kong

Completed

Oral Health Promotion Among Preschool Children With Special Needs

Epilepsy | Cerebral Palsy | Intellectual Disability | Down Syndrome | Developmental Disability | Developmental Delay | Learning Disorders | Autistic Spectrum Disorders | Developmental Disorders

China
Clinique Romande de Readaptation

Completed

LEAP a New Overground Body Weight Support Robot: Usability Trial (LEAP)

Stroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Spinal Cord Injuries | People With Impaired Lower Extremity Function

Switzerland
Baylor Research Institute
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Dosing Study of Replagal in Patients With Fabry Disease

Fabry Disease

United States
Johannes Gutenberg University Mainz

Unknown

Non-invasive Assessment of Intraocular Pressure in MPS by Use of the Ocular Response Analyzer. (MPSORA)

Mucopolysaccharidosis | Fabry Disease

Germany
Obslap Research LLC

Completed

My Scrivener® - Measuring Effectiveness and Dose Response in Children

Stroke | Cerebral Palsy | ADHD | Traumatic Brain Injury | Dyslexia | Attention Deficit Disorder | Asperger's Syndrome

United States
University of Parma

Unknown

Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides

Wegener's Granulomatosis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa

Italy
Tisento Therapeutics

Not yet recruiting

A Phase 2b Study of Zagociguat in Patients With MELAS (PRIZM)

Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

United States, Australia, Italy, Germany, Canada, United Kingdom
Sana Biotechnology

Recruiting

Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM) (GLEAM)

Systemic Lupus Erythematosus | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Lupus Erythematosus | SLE (Systemic Lupus) | Granulomatous Polyangiitis

United States
Sklifosovsky Institute of Emergency Care

Recruiting

Sonography-guided Resection of Brain Mass Lesions (SOMALI)

Arteriovenous Malformations | Tumor, Brain | Cavernoma | Intracerebral Hematoma

Russian Federation
Sanofi

Recruiting

A Study to Evaluate the Effect of Venglustat Tablets on Neuropathic and Abdominal Pain in Male and Female Participants ≥16 Years of Age With Fabry Disease (PERIDOT)

Fabry Disease

China, Finland, Germany, Norway, United Kingdom, United States, Denmark, Austria, Greece, Romania, Argentina, Brazil, Canada, Japan, Mexico, Poland, Italy, France, Turkey, Australia, Switzerland
Albina Nowak, MD
Swiss National Science Foundation

Recruiting

Effect of Cannabinoids on Pain in Fabry Disease Patients

Pain, Neuropathic

Switzerland
Universidad de Zaragoza
fundación española para el estudio y tratamiento de la Enfermedad de Gaucher... and other collaborators

Completed

Therapeutic Exercise to Treat Neuropathic Pain (Aps)

Fabry Disease | Gaucher Disease

Spain
Abant Izzet Baysal University
Hacettepe University

Unknown

Interrater Reliability of Infant Motor Profile (IMP)

Cerebral Palsy | Down Syndrome | Premature Infants | Spina Bifida | Metabolic Disorders | Low; Birthweight, Extremely (999 Grams or Less)
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors

Glioblastoma | Gliosarcoma | Medulloblastoma | Anaplastic Astrocytoma | Choroid Plexus Neoplasms | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Neuroectodermal Tumor, Primitive | Brainstem Tumors | Teratoid Tumor, Atypical

United States
Amicus Therapeutics

Completed

Safety and Pharmacokinetics of AT1001 (Migalastat HCl) in Healthy Subjects and Subjects With Impaired Renal Function

Fabry Disease

United States

Clinical Trials on Vertebral Metastasis

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