Clinical Trials on Wear, Tooth in Canada

Total 795 results

Pfizer

Terminated

A Study to Learn About the Effects of Sisunatovir in Infants With Respiratory Syncytial Virus Lower Respiratory Tract Infection. (REVIRAL 1)

Lower Resp Tract Infection | Respiratory Syncytial Virus (RSV)

Spain, Malaysia, Israel, Hungary, Poland, Taiwan, Costa Rica, United Kingdom, Thailand, Argentina, Canada, Chile, Korea, Republic of, New Zealand, Panama
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States, Canada
Laboratorios Leti, S.L.
Harrison Clinical Research

Terminated

Safety Study of Depigoid Vaccine Dermatophagoides Pteronyssinus or 50% Dermatophagoides Pteronyssinus / 50% Dermatophagoides Farinae (500 DPP/ml), to Treat Allergic Rhinitis or Rhinoconjunctivitis With or Without Asthma

Allergic Rhinitis | Mild Persistent Asthma | Rhinoconjunctivitis | Mild Intermittent Asthma

Spain
University of North Carolina, Chapel Hill
The Hospital for Sick Children; Washington University School of Medicine; McGill... and other collaborators

Recruiting

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

Primary Ciliary Dyskinesia | Kartagener Syndrome | Primary Immune Deficiency

United States, Canada
Novartis Pharmaceuticals

Withdrawn

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Basal Cell Carcinoma

Greece, Switzerland, Germany, United Kingdom, Belgium, Canada, Czechia, Finland, Italy, Spain
Columbia University
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) (NAMDC)

Mitochondrial Diseases | Mitochondrial Disorders | Mitochondrial Genetic Disorders | Disorder of Mitochondrial Respiratory Chain Complexes | Deletion and Duplication of Mitochondrial DNA

United States, Canada
Emory University
National Institute of Neurological Disorders and Stroke (NINDS); Allergan; Office... and other collaborators

Completed

The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias (DCP)

Dystonia

United States, Canada, Australia, Italy, Germany, France, United Kingdom
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0216, Combination Chemotherapy and RT in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Head and Neck Cancer

Canada, United States
GlaxoSmithKline

Completed

Study Of Adults And Adolescents With Vasomotor Rhinitis

Rhinitis, Vasomotor

United States, Germany, Canada, Czechia, Romania, Norway
University of North Carolina, Chapel Hill
National Institutes of Health (NIH); National Center for Research Resources... and other collaborators

Completed

Rare Genetic Disorders of the Breathing Airways

Cystic Fibrosis | Primary Ciliary Dyskinesia | Kartagener Syndrome | Pseudohypoaldosteronism

United States, Canada
National Cancer Institute (NCI)

Completed

Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors

Recurrent Salivary Gland Carcinoma | Salivary Gland Adenoid Cystic Carcinoma | Stage IV Major Salivary Gland Cancer AJCC v7 | Malignant Salivary Gland Neoplasm

United States, Canada
Takeda

Recruiting

A Study of Dexlansoprazole Delayed-Release Capsules to Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children

Gastroesophageal Reflux Disease (GERD)

United States, Lithuania, Mexico, Canada, Colombia, Poland
Shire

Completed

Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment (AIM-IT)

Hunter Syndrome

Spain, United States, Canada, United Kingdom, France, Australia, Mexico
Shire

Completed

An Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive Impairment

Hunter Syndrome

United States, United Kingdom, Canada
Novartis Pharmaceuticals

Recruiting

A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors

Mesothelioma

Australia, Switzerland, Italy, Spain, Canada, Germany, Japan, United Kingdom, Netherlands, United States, France
Adare Pharmaceuticals, Inc.

Completed

Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE) (FLUTE)

Eosinophilic Esophagitis

Spain, United States, Belgium, Switzerland, Germany, Canada
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION)

Head and Neck Cancer

United States, China, Belgium, Taiwan, Korea, Republic of, Japan, Israel, Brazil, Greece, Mexico, United Kingdom, Argentina, Austria, Czechia, France, Georgia, Germany, India, Italy, Portugal, Romania, Spain, Switzerland, Netherlands, P... and more
Novartis Pharmaceuticals

Active, not recruiting

Study of Safety and Tolerability of CFZ533 in Patients With Sjögren's Syndrome (TWINSS Extn)

Sjogren's Syndrome

United Kingdom, Netherlands, Australia, Austria, Israel, France, Germany, Greece, Hungary, Italy, United States, Korea, Republic of, Japan, Portugal, Russian Federation, Turkey, Colombia, Romania, Argentina, Chile, Brazil, Canada, S...
Abbott

Completed

Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis

Acute Bacterial Sinusitis (ABS)

Italy, Spain, Greece, United States, Canada, Poland, Lithuania, Hungary, Romania
Inmunotek S.L.

Recruiting

Efficacy and Safety Evaluation for the Treatment of Allergy Against Grass and Olive Pollen

Rhinitis, Allergic | Rhinoconjunctivitis | Asthma, Allergic

Spain
Hoffmann-La Roche

Completed

A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps (POLYP 1)

Nasal Polyps | Chronic Rhinosinusitis

Czechia, United States, Portugal, Germany, Canada, Ukraine, Poland, Mexico, Russian Federation, United Kingdom
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy and Radiation Therapy Following Surgery in Treating Patients With Head and Neck Cancer

Head and Neck Cancer

United States, Canada
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Pantoprazole in Neonates and Preterm Infants With GERD

Gastroesophageal Reflux

Belgium, Italy, United States, Australia, Canada, France, Germany, Netherlands, Poland, South Africa, Switzerland
Novartis Pharmaceuticals

Recruiting

A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced Cancers

Carcinoma, Renal Cell | Carcinoma, Non-Small-Cell Lung | Nasopharyngeal Carcinoma | Carcinoma, Ovarian Epithelial | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Neoplasms | Anal Cancer | Cutaneous Melanoma | Esophagogastric Cancer | Carcinoma, Thymic | High Microsatellite...

Italy, Spain, Singapore, Germany, Taiwan, Japan, Canada, Hong Kong, United States
Wyeth is now a wholly owned subsidiary of Pfizer
Nycomed

Completed

Study Evaluating Pantoprazole in Children With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux

United States, Canada
Ironwood Pharmaceuticals, Inc.

Completed

Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

Gastroesophageal Reflux Disease (GERD)

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy in Treating Patients With Stage II Cancer of the Vocal Cord

Head and Neck Cancer

United States, Canada
GlaxoSmithKline

Completed

Once-Daily Investigational Nasal Spray In Adults And Adolescents With Vasomotor Rhinitis

Vasomotor Rhinitis | Rhinitis, Vasomotor

United States, Romania, Czechia, Canada, Germany, Puerto Rico, Norway
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy and Cisplatin in Treating Patients With Advanced Head and Neck Cancer

Head and Neck Cancer

United States, Canada
Johns Hopkins University
Mayo Clinic; Medical University of Graz; Radboud University Medical Center; University... and other collaborators

Recruiting

Oral N-acetylcysteine for Retinitis Pigmentosa (NAC Attack)

Retinitis Pigmentosa

United States, Austria, Mexico, Netherlands, United Kingdom, Germany, Canada, Switzerland
GlaxoSmithKline

Completed

Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR)

Rhinitis, Allergic, Perennial

Australia, Estonia, United States, Germany, Canada, New Zealand, Russian Federation, Lithuania, Latvia
National Cancer Institute (NCI)
NRG Oncology

Terminated

Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer

Recurrent Nasopharyngeal Carcinoma | Stage IV Nasopharyngeal Carcinoma AJCC v8 | Metastatic Nasopharyngeal Carcinoma | Metastatic Nasopharyngeal Keratinizing Squamous Cell Carcinoma | Metastatic Nasopharyngeal Nonkeratinizing Carcinoma | Metastatic Nasopharyngeal Undifferentiated Carcinoma | Nasopharyngeal... and other conditions

United States, Canada, China, Singapore
AstraZeneca

Completed

Chest Pain Pilot Study

Chest Pain | Gastroesophageal Reflux

Sweden, Germany, Denmark, Norway, Canada, Netherlands
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy

Metastatic Colorectal Cancer | Squamous Cell Carcinoma of Head and Neck (SCCHN)

France, Belgium, Spain, Germany, Italy, Canada, United States
AnaptysBio, Inc.

Completed

Etokimab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Chronic Rhinosinusitis

United States
GlaxoSmithKline

Completed

Dose Finding Study of Fluticasone Furoate Nasal Spray for Uncomplicated Acute Rhinosinusitis

Sinusitis, Acute

Germany, Spain, Bulgaria, Czechia, Canada, Sweden, Netherlands, Estonia, Norway, Poland, Ukraine, Russian Federation
National Cancer Institute (NCI)
NRG Oncology

Suspended

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma | Squamous Cell Carcinoma | Basaloid Squamous Cell Carcinoma | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Papillary Squamous Cell Carcinoma | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States, Canada
Novartis Pharmaceuticals

Completed

Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome (TWINSS)

Sjögren Syndrome

United States, United Kingdom, Netherlands, Australia, Austria, Israel, France, Germany, Greece, Hungary, Italy, Korea, Republic of, Japan, Portugal, Russian Federation, Turkey, Canada, Colombia, Romania, Argentina, Chile, Brazil, S...
Braintree Laboratories

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Non-Erosive Reflux Disease

Non-erosive Reflux Disease

United States
Hoffmann-La Roche

Completed

A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas

Basal Cell Carcinoma

United States, Spain, France, Germany, Netherlands, Russian Federation, Italy, Mexico, Austria, Canada
St. Luke's-Roosevelt Hospital Center
National Eye Institute (NEI); University of Iowa; University of California, Davis and other collaborators

Completed

Idiopathic Intracranial Hypertension Treatment Trial (IIHTT)

Idiopathic Intracranial Hypertension

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Head and Neck Cancer

United States, Canada
Braintree Laboratories

Completed

Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease | GERD | Heartburn

United States
Novartis Pharmaceuticals

Recruiting

A Randomized, Double-blind 2-arm NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome. (NEPTUNUS-Ext)

Sjogrens Syndrome

United States, Spain, Austria, Belgium, Japan, Germany, Turkey, Hungary, Israel, Taiwan, Italy, France, Colombia, Argentina, Portugal, Sweden, Australia, Slovakia, United Kingdom, Guatemala, Brazil, Czechia, Poland, Bulgaria, Canada, Lith... and more
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Active, not recruiting

RT With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer

Head and Neck Cancer

United States, Canada, Saudi Arabia, China
GlaxoSmithKline
Bristol-Myers Squibb; CRF health

Completed

Effect of Mepolizumab in Severe Bilateral Nasal Polyps

Nasal Polyps

Australia, United States, Argentina, Netherlands, Russian Federation, Sweden, Germany, Korea, Republic of, United Kingdom, Canada, Romania
XenoPort, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy With or Without Epoetin Alfa in Treating Anemic Patients With Head and Neck Cancer

Head and Neck Cancer | Anemia

United States, Canada, Korea, Republic of
PellePharm, Inc.

Completed

Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)

Basal Cell Nevus Syndrome

United States, Spain, Germany, United Kingdom, Italy, France, Belgium, Canada, Denmark, Netherlands
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)

Allergic Fungal Rhinosinusitis

China, Argentina, Israel, United States, Canada, India, Japan, Saudi Arabia, Turkey

Clinical Trials on Wear, Tooth in Canada

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