Clinical Trials on X-linked Lymphoproliferative Syndrome 2

Total 3516 results

Alcobra Ltd.

Completed

A 6-week, Study of MG01CI Low Dose and High Dose Compared With Placebo in Adults and Adolescents With Fragile X Syndrome

Fragile X Syndrome

United States, Israel
Novartis Pharmaceuticals

Terminated

Long-term, Safety, Tolerability and Efficacy Study of AFQ056 in Adult Patients With Fragile X Syndrome

Fragile X Syndrome

Germany, United States, Switzerland, Australia, Canada, Denmark, France, Italy, United Kingdom, Spain
Seaside Therapeutics, Inc.

Completed

Efficacy and Safety Study of STX209 (Arbaclofen) for the Treatment of Social Withdrawal in Children With Fragile X Syndrome (Harbor-C)

Fragile X Syndrome

United States
Stanford University

Completed

An Open-Label Trial of Donepezil in Fragile X Syndrome

Fragile X Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1

Growth Failure | X-linked Severe Combined Immunodeficiency (XSCID) | Growth Hormone Resistence

United States
Genethon

Active, not recruiting

Gene Therapy for X-linked Chronic Granulomatous Disease (X-CGD) (CGD)

X-Linked Chronic Granulomatous Disease

United Kingdom
Parc de Salut Mar
Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Hospital Universitario... and other collaborators

Completed

Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS) (PERSEUS)

Down Syndrome | Fragile X Syndrome

Spain
Children's Hospital of Philadelphia
National Institute of Neurological Disorders and Stroke (NINDS); Vanderbilt...

Recruiting

Neurophysiologic Biomarkers in Rett Syndrome

Rett Syndrome | Rett Syndrome, Atypical | RTT

United States
Craig Erickson
Healx Limited

Recruiting

Placebo-Controlled, Single-Dose Challenge Study of Gaboxadol in Adult Males With Fragile X Syndrome (FXS)

Fragile X Syndrome

United States
Elizabeth Berry-Kravis

Completed

Single Blind Study of Ergoloid Mesylates, 5-HTP and the Combination in Adult Males With Fragile X Syndrome

Fragile X Syndrome

United States
Novartis Pharmaceuticals

Completed

Clinical Study to Assess the Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of AFQ056 in Children With Fragile X Syndrome (FXS)

Fragile X Syndrome

United States, Spain
Rowan University
University of Pennsylvania; FRAXA Research Foundation

Unknown

Metformin in Patients With Fragile X

Fragile X Syndrome

United States
Hoffmann-La Roche

Completed

A Study of RO4917523 in Pediatric Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Hoffmann-La Roche

Completed

A Study of RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

France, Spain, United States, Peru, Canada, United Kingdom, Chile, Argentina, Mexico, Sweden
Yolanda de Diego Otero

Completed

Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome (SXF-TRA152)

Fragile X Syndrome

Spain
Seaside Therapeutics, Inc.

Completed

Safety, Tolerability and Efficacy Study of STX209 in Subjects With Fragile X Syndrome

Fragile X Syndrome

United States
Seaside Therapeutics, Inc.

Terminated

An Open Label Extension Study of STX209 in Subjects With Fragile X Syndrome

Fragile X Syndrome

United States
David Williams

Active, not recruiting

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Gene Therapy | Severe Combined Immunodeficiency, X Linked

United States, United Kingdom
National Institute of Allergy and Infectious Diseases...

Unknown

Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency (LVXSCID-OC)

X-Linked Combined Immunodeficiency Diseases

United States
National Institute of Allergy and Infectious Diseases...

Completed

Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)

Severe Combined Immunodeficiency

United States
ACADIA Pharmaceuticals Inc.

Completed

Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LILAC™)

Rett Syndrome

United States
ACADIA Pharmaceuticals Inc.

Completed

Open-Label Extension Study of Trofinetide for Rett Syndrome

Rett Syndrome

United States
IRCCS Eugenio Medea
Associazione Italiana Rett (AIRett) O.n.l.u.s.

Completed

Tolerability of the Immersive Virtual Reality System Grail in Subjects Affected by Rett Syndrome

Rett Syndrome

Italy
Rett Syndrome Research Trust
Duke University

Completed

Development of the ORCA Communication Measure for Rett Syndrome (Rett-ORCA)

Rett Syndrome

United States
Anavex Life Sciences Corp.
International Rett Syndrome Foundation Rettsyndrome.org

Completed

Study of ANAVEX2-73 in Patients With Rett Syndrome

Rett Syndrome

United States
Montefiore Medical Center
Rett Syndrome Research Trust

Completed

Pharmacological Treatment of Rett Syndrome With Statins (Statins)

Rett Syndrome

United States
Montefiore Medical Center
Rett Syndrome Research Trust

Completed

Pharmacological Treatment of Rett Syndrome With Glatiramer Acetate (Copaxone)

Rett Syndrome

United States
Assistance Publique Hopitaux De Marseille

Completed

Pilot Study of the Effects of the Desipramine on the Neurovegetative Parameters of the Child With Rett Syndrome

Rett Syndrome

France
Medical University of Vienna

Completed

Effects of Creatine Supplementation in Rett Syndrome

Rett Syndrome

Austria
Nova Mentis Life Science Corp
FourthWall Testing

Recruiting

Establishing a Diagnostic and Therapeutic Index in Autism Spectrum Disorder (ASD) and Fragile X Syndrome

Autism Spectrum Disorder | Fra(X) Syndrome

United States
Fundación Pública Andaluza para la Investigación...
Delos Clinical

Completed

Clinical Trial for Asses the Safety and Efficacy of Vitamin C and Vitamin E in Combination Versus Placebo for Treating Cognitive and Behavior Disorder in Children With Fragile X Syndrome (SXF2-8)

X Fragile Syndrome

Spain
Université de Sherbrooke
Canadian Institutes of Health Research (CIHR); Centre de recherche du Centre... and other collaborators

Not yet recruiting

Effect of CANnabidiol on Anxiety and GABAergic Function in Individuals With Fragile-X Syndrome (CANAX)

Fragile X Syndrome
Tetra Discovery Partners

Recruiting

A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome

Fragile X Syndrome

United States
Children's Hospital of Fudan University

Recruiting

Metformin in Children With Fragile X Syndrome

Fragile X Syndrome | Metformin

China
Tetra Discovery Partners

Enrolling by invitation

An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome

Fragile X Syndrome

United States
Healx Limited

Withdrawn

Investigation of Sulindac (HLX-0201) and Gaboxadol (HLX-0206) in Male Fragile X Syndrome Patients Aged 13-40 (IMPACT-FXS)

Fragile X Syndrome

United States, Australia
Children's Hospital Medical Center, Cincinnati

Completed

An Initial Study of AZD7325 in Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Université de Sherbrooke
FRAXA Research Foundation

Completed

Metformin in Children and Adults With Fragile X Syndrome

Fragile X Syndrome

Canada
Novartis

Completed

Efficacy, Safety and Tolerability of AFQ056 in Fragile X Patients

Fragile X Syndrome

France, Italy, Switzerland
Neuren Pharmaceuticals Limited

Completed

A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Randi J. Hagerman, MD

Completed

Trial of Sertraline to Treat Children With Fragile X Syndrome

Fragile X Syndrome

United States
Indiana University
Indiana Clinical and Translational Sciences Institute

Completed

Riluzole in Fragile X Syndrome

Fragile X Syndrome

United States
Indiana University School of Medicine

Completed

A Prospective Open-label Study of Aripiprazole in Fragile X Syndrome

Fragile X Syndrome

United States
Hoffmann-La Roche

Completed

A Study With RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Novartis Pharmaceuticals

Terminated

Long-term, Safety and Tolerability Study of AFQ056 in Adolescent Patients With Fragile X Syndrome (Open-label)

Fragile X Syndrome

United States, Belgium, Australia, Israel, Switzerland, Germany, Denmark, Italy, Netherlands, Spain, Sweden, United Kingdom, France
Stanford University
National Institute of Mental Health (NIMH); Autism Speaks

Completed

Randomized Controlled Study of Donepezil in Fragile X Syndrome

Fragile X Syndrome

United States
FRAXA Research Foundation
Fragile X Research Foundation of Canada

Completed

Add-on Pilot Trial of Minocycline to Treat Fragile X Syndrome

Fragile X Syndrome

Canada
Novartis Pharmaceuticals

Completed

Safety and Efficacy of AFQ056 in Adolescent Patients With Fragile X Syndrome

Fragile X Syndrome

United States, Belgium, Australia, Israel, Switzerland, Germany, France, Canada, Denmark, Indonesia, Italy, Netherlands, Spain, Sweden, Turkey, United Kingdom
Seaside Therapeutics, Inc.

Completed

Biomarker Testing and DNA Collection in Subjects Participating in Protocol 22001

Fragile X Syndrome

United States
Seaside Therapeutics, Inc.

Completed

Efficacy and Safety Study of STX209 (Arbaclofen) for Social Withdrawal in Adolescents and Adults With Fragile X Syndrome (Harbor-A)

Fragile X Syndrome

United States

Clinical Trials on X-linked Lymphoproliferative Syndrome 2

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