Search clinical trials for: (-)-Epicatechin (EC)

Total 351 results

Veterans Medical Research Foundation
University of California, San Diego; National Institutes of Health (NIH); National... and other collaborators

Completed

Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Epicatechin)

Pre-diabetes

United States
Quadram Institute Bioscience
Danisco; Coressence LTD

Completed

Bioavailability and Vascular Effects of Apple Polyphenols (POLYMALUS)

Healthy

United Kingdom
University of Reading

Completed

An Investigation of the Dose-dependent Vascualr Effects of (-)-Epicatechin in Healthy Men

Vasodilation

United Kingdom
University of California, San Diego
The Hershey Company

Completed

Effects of Dark Chocolate on Exercise Capacity, and Mitochondrial Structure and Function

Heart Failure | Type 2 Diabetes

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Developing E-liquid Product Standards (Sweet Spot Study)

Nicotine | Nicotine Vaping | E-cigarette Use

United States
Enzychem Lifesciences Corporation

Completed

To Evaluate Safety and Efficacy of EC-18 in COVID-19 Infection to Pneumonia

COVID-19

Korea, Republic of
Ralitza Gavrilova
Cardero Therapeutics, Inc.

Completed

(+) Epicatechin to Treat Friedreich's Ataxia

Friedreich's Ataxia

United States
Radboud University Medical Center
Norgine

Unknown

Comparison of AMR and ADR Between Endocuff Vision-assisted and Conventional Colonoscopy: a Multicenter Randomized Trial (EXCEED)

Colorectal Neoplasms

Netherlands, Greece
University of California, Davis

Completed

Effects of Epicatechin-rich Cocoa on Collagen Synthesis (coca-dose)

Collagen Synthesis

United States
Enzychem Lifesciences Corporation

Completed

Management of Severe Chemotherapy-induced Neutropenia in Advanced Breast Cancer

Febrile Neutropenia

Korea, Republic of
Enzychem Lifesciences Corporation

Completed

A Safety and PK Study of EC-18 in Healthy Subjects

Chemotherapy-induced Neutropenia

United States
Craig McDonald, MD
Cardero Therapeutics, Inc.

Completed

(-)- Epicatechin Becker Muscular Dystrophy

Becker Muscular Dystrophy

United States
Danisco
University of Turku; 4Pharma Ltd.

Completed

Effect of an Apple Polyphenol Extract on Brachial Artery Flow-mediated Vasodilatory Function

Borderline Hypertension

Finland
Prof. Dominique de Quervain, MD

Completed

Influence of Chocolate With Plant Additives on Episodic Memory in Healthy Subjects Experiencing Test Anxiety (MaRS-Basel)

Test Anxiety

Switzerland
PENTAX Europe GmbH
Johannes Gutenberg University Mainz

Terminated

Endomicroscopy in Ulcerative Colitis

Ulcerative Colitis

Germany, Italy
Craig McDonald, MD
Cardero Therapeutics, Inc.

Completed

Plus Epicatechin Duchenne Muscular Dystrophy in Non-ambulatory Adolescents

Duchenne Muscular Dystrophy

United States
Veterans Medical Research Foundation
University of California, San Diego; National Institutes of Health (NIH); National... and other collaborators

Completed

Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2) (Epicatechin)

Pre-diabetes

United States
Cryonove Pharma

Not yet recruiting

Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face (CS5_10B)

Lentigo | Solar Lentigo | Post Inflammatory Hyperpigmentation
University of California, Davis
Mars, Inc.

Completed

Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans

Healthy

United States
University Ghent

Completed

The Influence of the Microbiome on the Pharmacokinetics of Flavan-3-ols (PhTI)

Diet Modification

Belgium
University of California, San Diego

Completed

Effects of Epicatechin on Functional Capacity, Skeletal Muscle Structure and Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction (HFPEF) (HFPEF)

Heart Failure

United States
National Polytechnic Institute, Mexico
Instituto Nacional de Salud Publica, Mexico; Universidad Nacional Autonoma... and other collaborators

Unknown

Effects of COcoa Supplement in OBese Adolescent Subjects (COOBA)

Childhood Obesity | Adolescent Obesity
Enzychem Lifesciences Corporation

Completed

Study to Evaluate the Safety, Tolerability and PK of EC-18 After Oral Administration in Healthy Volunteers

Chemotherapy-Induced Neutropenia

Korea, Republic of
University of California, San Francisco

Withdrawn

(-)-Epicatechin and Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States
Geisinger Clinic
Penn State University

Completed

Teaching Appropriate Gestational Weight Gain (TAGG)

Obesity

United States
Yale University
National Institutes of Health (NIH)

Not yet recruiting

Peer-led Implementation of TB-HIV Education and Adherence Counseling in Uganda (TEACH)

HIV | Tuberculosis

Uganda
Enzychem Lifesciences Corporation

Completed

EC-18 for Oral Mucositis in Patients With Concomitant Chemoirradiation

Stomatitis

United States
University of Chicago

Completed

Chicago Community Health Study (CCHS)

Smoking

United States
Lycera Corp.

Completed

An Efficacy and Safety Study of LYC-30937-EC in Subjects With Active Ulcerative Colitis

Colitis, Ulcerative

United States, Czechia, Hungary, Netherlands, Poland, Serbia, Canada
Ferdowsi University of Mashhad

Recruiting

Disgust Reduction Through Evaluative Conditioning (DREC) and tDCS in Contamination-Based OCD

Obsessive-Compulsive Disorder

Iran, Islamic Republic of
Epirium Bio Inc.

Completed

Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy

Becker Muscular Dystrophy

United States
University of California, Los Angeles

Completed

Promoting Resiliency in Veteran Families With Young Children (FOCUS-EC)

Depression | Stress, Psychological | Stress Disorders, Traumatic | Anxiety | Emotional Stress | Trauma, Psychological | Behavior, Child | Regulation, Self
Baylor College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

The Children in Action Feasibility Study (CIA)

Obesity | Motor Activity
Lycera Corp.

Completed

An Efficacy and Safety Study of LYC-30937-EC in Subjects With Moderate Chronic Plaque-type Psoriasis

Psoriasis

United States
Memorial Sloan Kettering Cancer Center
National Institute of Nursing Research (NINR); University of Virginia

Completed

Lung Cancer Informational Study (LCIS)

Cancer | Stage IV Lung Cancer | Stage III Lung Cancer | Decision-Making | Enhanced Care | Advance Lung Cancer

United States
Cancer Therapeutics Research Group
National Cancer Institute (NCI)

Completed

Irofulven in Treating Patients With Recurrent or Metastatic Gastric Cancer

Gastric Cancer

Australia, Singapore, Hong Kong, Korea, Republic of
Cedars-Sinai Medical Center
National Institutes of Health (NIH)

Completed

Surgical Indirect Revascularization For Symptomatic Intracranial Arterial Stenosis (ERSIAS)

Ischemic Stroke | Intracranial Atherosclerosis | Intracranial Arterial Stenosis | Cerebral Angiogenesis

United States
Enzychem Lifesciences Corporation

Recruiting

Prevention of COVID-19 Infection to Severe Pneumonia or ARDS

Covid19 Pneumonia

United States
University College, London
Cancer Research UK

Terminated

Electrocautery Ablation for the Prevention of Lung Cancer (EARL)

Lung Cancer Squamous Cell

United Kingdom
University of Chicago

Completed

Feasibility of Imaging in the Treatment of Patients With Advanced Head and Neck Cancer

Head and Neck Cancer

United States
Lycera Corp.

Terminated

Open-label Extension Study to Assess Safety and Tolerability of LYC-30937-EC in Subjects With Active Ulcerative Colitis

Colitis, Ulcerative

United States, Czechia, Hungary, Netherlands, Poland, Serbia
Vienna Institute for Research in Ocular Surgery

Completed

Aqueous Flare of a Hydrophobic Acrylic Single-piece Open-loop IOL With Modified Material Surface Properties (POL)

Diabetes | Cataract | Pseudoexfoliation Syndrome

Austria
Craig McDonald, MD
Cardero Therapeutics, Inc.

Completed

Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)

Becker Muscular Dystrophy

United States
Wageningen University
Top Institute Food and Nutrition

Completed

Comparison of Pure Epicatechin and Cocoa on Markers of Vascular Function (FLAVO2)

Endothelial Dysfunction | Bioavailability

Netherlands
Dendreon

Completed

Dose Escalation Study of EC D-3263 HCl in Advanced Solid Tumors

Solid Tumors

United States
University of Rochester
Johns Hopkins University; University of Arkansas

Recruiting

Telemedicine Enhanced Asthma Management - Uniting Providers for Teens (TEAM-UP for Teens)

Asthma in Children

United States
POZEN

Completed

A Pharmacokinetic (PK) Study Evaluating Naproxen and Esomeprazole Plasma Levels

Arthritis

United States
Quadram Institute Bioscience

Completed

The Effects of Apple Derived Flavanols on Cardiovascular Disease Risk (FLAVASCULAR Study) (FLAVASCULAR)

Blood Pressure

United Kingdom
Sorlandet Hospital HF

Completed

ColoAssist vs. MEI

Colorectal Cancer | Screening

Norway
University of Michigan
Michigan State University; One Mind Institute

Completed

Neurally Targeted Interventions to Reduce Early Childhood Anxiety

Anxiety Disorders

United States

Search clinical trials for: (-)-Epicatechin (EC)

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